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Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome Domenech-Moreno, Eva; Lim, Wei-Wen; Montrose, Melissa G.; Sevigny, Myriam; Brandt, Anders; Lemmetyinen, Toni T.; Viitala, Emma W.; Makela, Tomi P.; Cook, Stuart A.; Ollila, Saara Share Save
Interleukin-11 causes alveolar type 2 cell dysfunction and prevents alveolar regeneration Ng, Benjamin; Huang, Kevin Y.; Pua, Chee Jian; Viswanathan, Sivakumar; Lim, Wei-Wen; Kuthubudeen, Fathima F.; Liu, Yu-Ning; Hii, An An; George, Benjamin L.; Widjaja, Anissa A.; Petretto, Enrico; Cook, Stuart A. Share Save
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Genotype-Phenotype Taxonomy of Hypertrophic Cardiomyopathy Curran, Lara; de Marvao, Antonio; Inglese, Paolo; McGurk, Kathryn A.; Schiratti, Pierre-Raphael; Clement, Adam; Zheng, Sean L.; Li, Surui; Pua, Chee Jian; Shah, Mit; Jafari, Mina; Theotokis, Pantazis; Buchan, Rachel J.; Jurgens, Sean J.; Raphael, Claire E.; Baksi, Arun John; Pantazis, Antonis; Halliday, Brian P.; Pennell, Dudley J.; Bai, Wenjia; Chin, Calvin W. L.; Tadros, Rafik; Bezzina, Connie R.; Watkins, Hugh; Cook, Stuart A.; Prasad, Sanjay K.; Ware, James S.; O'Regan, Declan P. Share Save
The penetrance of rare variants in cardiomyopathy-associated genes: A cross-sectional approach to estimating penetrance for secondary findings Mcgurk, Kathryn A.; Zhang, Xiaolei; Theotokis, Pantazis; Thomson, Kate; Harper, Andrew; Buchan, Rachel J.; Mazaika, Erica; Ormondroyd, Elizabeth; Wright, William T.; Macaya, Daniela; Pua, Chee Jian; Funke, Birgit; Macarthur, Daniel G.; Prasad, Sanjay K.; Cook, Stuart A.; Allouba, Mona; Aguib, Yasmine; Yacoub, Magdi H.; O'Regan, Declan P.; Barton, Paul J. R.; Watkins, Hugh; Bottolo, Leonardo; Ware, James S. Share Save
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Integrin-linked kinase regulates endothelial cell survival and vascular development Friedrich, EB; Liu, E; Sinha, S; Cook, S; Milstone, DS; MacRae, CA; Mariotti, M; Kuhlencordt, PJ; Force, T; Rosenzweig, A; St-Arnaud, R; Dedhar, S; Gerszten, RE Share Save
The Singapore National Precision Medicine Strategy Wong, Eleanor; Bertin, Nicolas; Hebrard, Maxime; Tirado-Magallanes, Roberto; Bellis, Claire; Lim, Weng Khong; Chua, Chee Yong; Tong, Philomena Mei Lin; Chua, Raymond; Mak, Kenneth; Lim, Tit Meng; Cheong, Wei Yang; Thien, Kwee Eng; Goh, Khean Teik; Chai, Jin-Fang; Lee, Jimmy; Sung, Joseph Jao-Yiu; Wong, Tien Yin; Chin, Calvin Woon Loong D.; Gluckman, Peter; Goh, Liuh Ling; Ban, Kenneth Hon Kim; Tan, Tin Wee M.; Van Dam, Rob M.; Teo, Yik Ying; Loh, Marie; Eillot, Paul; Lee, Eng Sing; Ngeow, Joanne; Riboli, Elio; Dalan, Rinkoo; Kassam, Irfahan; Lakshmanan, Lakshmi Narayanan; Lim, Tock Han; Ng, Hong Kiat; Mina, Theresia; Tay, Darwin; Sabanayagam, Charumathi; Tham, Yih Chung; Rim, Tyler; Aung, Tin; Chee, Miao Ling; Li, Hengtong; Chee, Miao Li; Yeo, Khung Keong; Cook, Stuart Alexander; Pua, Chee Jian; Yang, Chengxi; Chong, Yap Seng; Eriksson, Johan Gunnar; Tan, Kok Hian; Yap, Fabian; Lim, Chia Wei; Tsai, Pi Kuang; Chew, Wen Jie; Sim, Wey Ching; Toh, Li-xian Grace; Lin, Clarabelle Bitong; Sia, Yee Yen; Koh, Tat Hung; Meah, Wee Yang; Tan, Joanna Hui Juan; Jeyakani, Justin; Ow, Jack; Ang, Shimin; Malik, Ashar J.; Kenanov, Dimitar; Sim, Xueling; Cheng, Ching-Yu; Davila, Sonia; Karnani, Neerja; Leong, Khai Pang; Liu, Jianjun; Prabhakar, Shyam; Maurer-Stroh, Sebastian; Verma, Chandra Shekhar; Krishnaswamy, Pavitra; Goh, Rick Siow Mong; Chia, Irenaeus; Ho, Clarissa; Low, Doreen; Virabhak, Suchin; Yong, Jacklyn; Zheng, Weiling; Seow, Shih Wee; Seck, Yee Kwang; Koh, Mingshi; Chambers, John C.; Tai, E. Shyong; Tan, Patrick Share Save
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease Widjaja, Anissa A.; Viswanathan, Sivakumar; Shekeran, Shamini G.; Adami, Eleonora; Lim, Wei-Wen; Chothani, Sonia; Tan, Jessie; Goh, Joyce Wei Ting; Chen, Hui Mei; Lim, Sze Yun; Boustany-Kari, Carine M.; Hawkins, Julie; Petretto, Enrico; Huebner, Norbert; Schafer, Sebastian; Coffman, Thomas M.; Cook, Stuart A. Share Save
Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation Tripathi, Madhulika; Singh, Brijesh Kumar; Zhou, Jin; Tikno, Keziah; Widjaja, Anissa; Sandireddy, Reddemma; Arul, Kabilesh; Ghani, Siti Aishah Binte Abdul; Bee, George Goh Boon; Wong, Kiraely Adam; Pei, Ho Jia; Shekeran, Shamini Guna; Sinha, Rohit Anthony; Singh, Manvendra K.; Cook, Stuart Alexander; Suzuki, Ayako; Lim, Teegan Reina; Cheah, Chang-Chuen; Wang, Jue; Xiao, Rui-Ping; Zhang, Xiuqing; Chow, Pierce Kah Hoe; Yen, Paul Michael Share Save
Genetic Architecture of Acute Myocarditis and the Overlap With Inherited Cardiomyopathy Lota, Amrit S.; Hazebroek, Mark R.; Theotokis, Pantazis; Wassall, Rebecca; Salmi, Sara; Halliday, Brian P.; Tayal, Upasana; Verdonschot, Job; Meena, Devendra; Owen, Ruth; de Marvao, Antonio; Iacob, Alma; Yazdani, Momina; Hammersley, Daniel J.; Jones, Richard E.; Wage, Riccardo; Buchan, Rachel; Vivian, Fredrik; Hafouda, Yakeen; Noseda, Michela; Gregson, John; Mittal, Tarun; Wong, Joyce; Robertus, Jan Lukas; Baksi, A. John; Vassiliou, Vassilios; Tzoulaki, Ioanna; Pantazis, Antonis; Cleland, John G. F.; Barton, Paul J. R.; Cook, Stuart A.; Pennell, Dudley J.; Garcia-Pavia, Pablo; Cooper, Leslie T., Jr.; Heymans, Stephane; Ware, James S.; Prasad, Sanjay K. Share Save
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression Zhou, Jin; Pang, Jeremy; Tripathi, Madhulika; Ho, Jia Pei; Widjaja, Anissa Anindya; Shekeran, Shamini Guna; Cook, Stuart Alexander; Suzuki, Ayako; Diehl, Anna Mae; Petretto, Enrico; Singh, Brijesh Kumar; Yen, Paul Michael Share Save
Markers of Focal and Diffuse Nonischemic Myocardial Fibrosis Are Associated With Adverse Cardiac Remodeling and Prognosis in Patients With Hypertension: The REMODEL Study Iyer, Nithin R.; Le, Thu-Thao; Kui, Michelle S. L.; Tang, Hak-Chiaw; Chin, Chee-Tang; Phua, Soon-Kieng; Bryant, Jennifer A.; Pua, Chee-Jian; Ang, Briana; Toh, Desiree-Faye; Aw, Tar-Choon; Lee, Chi-Hang; Cook, Stuart A.; Ugander, Martin; Chin, Calvin W. L. Share Save
A high-resolution map of human RNA translation Chothani, Sonia P.; Adami, Eleonora; Widjaja, Anissa A.; Langley, Sarah R.; Viswanathan, Sivakumar; Pua, Chee Jian; Zhihao, Nevin Tham; Harmston, Nathan; D'Agostino, Giuseppe; Whiffin, Nicola; Mao, Wang; Ouyang, John F.; Lim, Wei Wen; Lim, Shiqi; Lee, Cheryl Q. E.; Grubman, Alexandra; Chen, Joseph; Kovalik, J. P.; Tryggvason, Karl; Polo, Jose M.; Ho, Lena; Cook, Stuart A.; Rackham, Owen J. L.; Schafer, Sebastian Share Save
High-Resolution Digital Phenotypes From Consumer Wearables and Their Applications in Machine Learning of Cardiometabolic Risk Markers: Cohort Study Zhou, Weizhuang; Chan, Yu En; Foo, Chuan Sheng; Zhang, Jingxian; Teo, Jing Xian; Davila, Sonia; Huang, Weiting; Yap, Jonathan; Cook, Stuart; Tan, Patrick; Chin, Calvin Woon-Loong; Yeo, Khung Keong; Lim, Weng Khong; Krishnaswamy, Pavitra Share Save
Thyroid Hormone Decreases Hepatic Steatosis, Inflammation, and Fibrosis in a Dietary Mouse Model of Nonalcoholic Steatohepatitis Zhou, Jin; Tripathi, Madhulika; Ho, Jia Pei; Widjaja, Anissa Anindya; Shekeran, Shamini Guna; Camat, Macalinao Dominique; James, Anne; Wu, Yajun; Ching, Jianhong; Kovalik, Jean-Paul; Lim, Kiat-Hon; Cook, Stuart Alexander; Bay, Boon-Huat; Singh, Brijesh Kumar; Yen, Paul Michael Share Save
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome Lim, Wei-Wen; Dong, Jinrui; Ng, Benjamin; Widjaja, Anissa A.; Xie, Chen; Su, Liping; Kwek, Xiu-Yi; Tee, Nicole G. Z.; Pua, Chee Jian; Schafer, Sebastian; Viswanathan, Sivakumar; Cook, Stuart A. Share Save
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