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Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics Korell, Felix; Olson, Michael L.; Salas-Benito, Diego; Leick, Mark B.; Larson, Rebecca C.; Bouffard, Amanda; Silva, Harrison; Gasparetto, Alessandro; Berger, Trisha R.; Kann, Michael C.; Mergen, Markus; Kienka, Tamina; Wehrli, Marc; Haradhvala, Nicholas J.; Bailey, Stefanie R.; Letai, Anthony; Maus, Marcela V. Share Save
Stealth transgenes enable CAR-T cells to evade host immune responses Grauwet, Korneel; Berger, Trisha; Kann, Michael C.; Silva, Harrison; Larson, Rebecca; Leick, Mark B.; Bailey, Stefanie R.; Bouffard, Amanda A.; Millar, David; Gallagher, Kathleen; Turtle, Cameron J.; Frigault, Matthew J.; Maus, Marcela, V Share Save
Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma Wehrli, Marc; Guinn, Samantha; Birocchi, Filippo; Kuo, Adam; Sun, Yi; Larson, Rebecca C.; Almazan, Antonio J.; Scarfo, Irene; Bouffard, Amanda A.; Bailey, Stefanie R.; Anekal, Praju Vikas; Montero Llopis, Paula; Nieman, Linda T.; Song, Yuhui; Xu, Katherine H.; Berger, Trisha R.; Kann, Michael C.; Leick, Mark B.; Silva, Harrison; Salas-Benito, Diego; Kienka, Tamina; Grauwet, Korneel; Armstrong, Todd D.; Zhang, Rui; Zhu, Qingfeng; Fu, Juan; Schmidts, Andrea; Korell, Felix; Jan, Max; Choi, Bryan D.; Liss, Andrew S.; Boland, Genevieve M.; Ting, David T.; Burkhart, Richard A.; Jenkins, Russell W.; Zheng, Lei; Jaffee, Elizabeth M.; Zimmerman, Jacquelyn W.; Maus, Marcela V. Share Save
Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7 Kann, Michael C.; Schneider, Emily M.; Almazan, Antonio J.; Lane, Isabel C.; Bouffard, Amanda A.; Supper, Valentina M.; Takei, Hana N.; Tepper, Alexander; Leick, Mark B.; Larson, Rebecca C.; Ebert, Benjamin L.; Maus, Marcela V.; Jan, Max Share Save
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening Ramos, Azucena; Koch, Catherine E.; Liu-Lupo, Yunpeng; Hellinger, Riley D.; Kyung, Taeyoon; Abbott, Keene L.; Frose, Julia; Goulet, Daniel; Gordon, Khloe S.; Eidell, Keith P.; Leclerc, Paul; Whittaker, Charles A.; Larson, Rebecca C.; Muscato, Audrey J.; Yates, Kathleen B.; Dubrot, Juan; Doench, John G.; Regev, Aviv; Vander Heiden, Matthew G.; Maus, Marcela V.; Manguso, Robert T.; Birnbaum, Michael E.; Hemann, Michael T. Share Save
Anti-TACI single and dual-targeting CAR T cells overcome BCMA antigen loss in multiple myeloma Larson, Rebecca C.; Kann, Michael C.; Graham, Charlotte; Mount, Christopher W.; Castano, Ana P.; Lee, Won-Ho; Bouffard, Amanda A.; Takei, Hana N.; Almazan, Antonio J.; Scarfo, Irene; Berger, Trisha R.; Schmidts, Andrea; Frigault, Matthew J.; Gallagher, Kathleen M. E.; Maus, Marcela V. Share Save
Chimeric antigen receptor (CAR) T cells overexpressing Bcl-xL increase proliferation and antitumor activity alone and in combination with BH3 mimetics Korell, Felix; Olson, Michael; Salas-Benito, Diego; Leick, Mark B.; Larson, Rebecca C.; Silva, Harrison; Gasparetto, Alessandro; Berger, Trisha R.; Bouffard, Amanda; Kann, Michael C.; Mergen, Markus; Kienka, Tamina; Wehrli, Marc; Bailey, Stefanie R.; Letai, Anthony; Maus, Marcela V. Share Save
Systematic Interrogation of Tumor Cell Resistance to Chimeric Antigen Receptor T-cell Therapy in Pancreatic Cancer Hagel, Kimberly R.; Arafeh, Rand; Gang, Sydney; Arnoff, Taylor E.; Larson, Rebecca C.; Doench, John G.; Mathewson, Nathan D.; Wucherpfennig, Kai W.; Maus, Marcela, V; Hahn, William C. Share Save
Tandem chimeric antigen receptor (CAR) T cells targeting EGFRvIII and IL-13Rα2 are effective against heterogeneous glioblastoma Schmidts, Andrea; Srivastava, Ambike A.; Ramapriyan, Rishab; Bailey, Stefanie R.; Bouffard, Amanda A.; Cahill, Daniel P.; Carter, Bob S.; Curry, William T.; Dunn, Gavin P.; Frigault, Matthew J.; Gerstner, Elizabeth R.; Ghannam, Jack Y.; Kann, Michael C.; Larson, Rebecca C.; Leick, Mark B.; Nahed, Brian, V; Richardson, Leland G.; Scarfo, Irene; Sun, Jing; Wakimoto, Hiroaki; Maus, Marcela, V; Choi, Bryan D. Share Save
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma Haradhvala, Nicholas J.; Leick, Mark B.; Maurer, Katie; Gohil, Satyen H.; Larson, Rebecca C.; Yao, Ning; Gallagher, Kathleen M. E.; Katsis, Katelin; Frigault, Matthew J.; Southard, Jackson; Li, Shuqiang; Kann, Michael C.; Silva, Harrison; Jan, Max; Rhrissorrakrai, Kahn; Utro, Filippo; Levovitz, Chaya; Jacobs, Raquel A.; Slowik, Kara; Danysh, Brian P.; Livak, Kenneth J.; Parida, Laxmi; Ferry, Judith; Jacobson, Caron; Wu, Catherine J.; Getz, Gad; Maus, Marcela, V Share Save
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CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity Joung, Julia; Kirchgatterer, Paul C.; Singh, Ankita; Cho, Jang H.; Nety, Suchita P.; Larson, Rebecca C.; Macrae, Rhiannon K.; Deasy, Rebecca; Tseng, Yuen-Yi; Maus, Marcela, V; Zhang, Feng Share Save
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Blockade or Deletion of IFNγ Reduces Macrophage Activation without Compromising CAR T-cell Function in Hematologic Malignancies Bailey, Stefanie R.; Vatsa, Sonika; Larson, Rebecca C.; Bouffard, Amanda A.; Scarfo, Irene; Kann, Michael C.; Berger, Trisha R.; Leick, Mark B.; Wehrli, Marc; Schmidts, Andrea; Silva, Harrison; Lindell, Kevin A.; Demato, Ashley; Gallagher, Kathleen M. E.; Frigault, Matthew J.; Maus, Marcela, V Share Save
Antibody and T-cell responses to SARS-CoV-2 vaccination in myeloproliferative neoplasm patients How, Joan; Gallagher, Kathleen M. E.; Liu, Yiwen; Katsis, Katelin; Elder, Eva L.; Larson, Rebecca C.; Leick, Mark B.; Neuberg, Donna; Maus, Marcela V.; Hobbs, Gabriela S. Share Save
Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2 (vol 21, 580, 2021) Trombetta, Bianca A.; Kandigian, Savannah E.; Kitchen, Robert R.; Grauwet, Korneel; Webb, Pia Kivisakk; Miller, Glenn A.; Jennings, Charles G.; Jain, Sejal; Miller, Samara; Kuo, Yikai; Sweeney, Thadryan; Gilboa, Tal; Norman, Maia; Simmons, Daimon P.; Ramirez, Christopher E.; Bedard, Melissa; Fink, Catherine; Ko, Jina; Peralta, Esmarline J. De Leon; Watts, Gerald; Gomez-Rivas, Emma; Davis, Vannessa; Barilla, Rocky M.; Wang, Jianing; Cunin, Pierre; Bates, Samuel; Morrison-Smith, Chevaun; Nicholson, Benjamin; Wong, Edmond; El-Mufti, Leena; Kann, Michael; Bolling, Anna; Fortin, Brooke; Ventresca, Hayden; Zhou, Wen; Pardo, Santiago; Kwock, Megan; Hazra, Aditi; Cheng, Leo; Ahmad, Q. Rushdy; Toombs, James A.; Larson, Rebecca; Pleskow, Haley; Luo, Nell Meosky; Samaha, Christina; Pandya, Unnati M.; De Silva, Pushpamali; Zhou, Sally; Ganhadeiro, Zakary; Yohannes, Sara; Gay, Rakiesha; Slavik, Jacqueline; Mukerji, Shibani S.; Jarolim, Petr; Walt, David R.; Carlyle, Becky C.; Ritterhouse, Lauren L.; Suliman, Sara Share Save
Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2 Trombetta, Bianca A.; Kandigian, Savannah E.; Kitchen, Robert R.; Grauwet, Korneel; Webb, Pia Kivisaekk; Miller, Glenn A.; Jennings, Charles G.; Jain, Sejal; Miller, Samara; Kuo, Yikai; Sweeney, Thadryan; Gilboa, Tal; Norman, Maia; Simmons, Daimon P.; Ramirez, Christopher E.; Bedard, Melissa; Fink, Catherine; Ko, Jina; Peralta, Esmarline J. De Leon; Watts, Gerald; Gomez-Rivas, Emma; Davis, Vannessa; Barilla, Rocky M.; Wang, Jianing; Cunin, Pierre; Bates, Samuel; Morrison-Smith, Chevaun; Nicholson, Benjamin; Wong, Edmond; El-Mufti, Leena; Kann, Michael; Bolling, Anna; Fortin, Brooke; Ventresca, Hayden; Zhou, Wen; Pardo, Santiago; Kwock, Megan; Hazra, Aditi; Cheng, Leo; Ahmad, Q. Rushdy; Toombs, James A.; Larson, Rebecca; Pleskow, Haley; Luo, Nell Meosky; Samaha, Christina; Pandya, Unnati M.; De Silva, Pushpamali; Zhou, Sally; Ganhadeiro, Zakary; Yohannes, Sara; Gay, Rakeisha; Slavik, Jacqueline; Mukerji, Shibani S.; Jarolim, Petr; Walt, David R.; Carlyle, Becky C.; Ritterhouse, Lauren L.; Suliman, Sara Share Save
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