Not logged in The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome (vol 11, 200, 2025) Omar, Ramla; Lee, Michelle A. W.; Gonzalez-Trueba, Laura; Thomson, Cameron R.; Hansen, Uwe; Lianos, Spyridonas; Hazarika, Snoopy; El Abdallah, Omar H. M. E. H.; Ammar, Malak A.; Cassels, Jennifer; Michie, Alison M.; Bulleid, Neil J.; Malfait, Fransiska; Van Agtmael, Tom Share Save
The chemical chaperone 4-phenylbutyric acid rescues molecular cell defects of COL3A1 mutations that cause vascular Ehlers Danlos Syndrome Omar, Ramla; Lee, Michelle A. W.; Gonzalez-Trueba, Laura; Thomson, Cameron R.; Hansen, Uwe; Lianos, Spyridonas; Hazarika, Snoopy; El Abdallah, Omar El; Ammar, Malak A.; Cassels, Jennifer; Michie, Alison M.; Bulleid, Neil J.; Malfait, Fransiska; Van Agtmael, Tom Share Save
Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells Donnelly, Hannah; Ross, Ewan; Xiao, Yinbo; Hermantara, Rio; Taqi, Aqeel F.; Doherty-Boyd, W. Sebastian; Cassels, Jennifer; Tsimbouri, Penelope. M.; Dunn, Karen M.; Hay, Jodie; Cheng, Annie; Meek, R. M. Dominic; Jain, Nikhil; West, Christopher; Wheadon, Helen; Michie, Alison M.; Peault, Bruno; West, Adam G.; Salmeron-Sanchez, Manuel; Dalby, Matthew J. Share Save
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors Wiesheu, Robert; Edwards, Sarah C.; Hedley, Ann; Hall, Holly; Tosolini, Marie; da Silva, Marcelo Gregorio Filho Fares; Sumaria, Nital; Castenmiller, Suzanne M.; Wardak, Leyma; Optaczy, Yasmin; Lynn, Amy; Hill, David G.; Hayes, Alan J.; Hay, Jodie; Kilbey, Anna; Shaw, Robin; Whyte, Declan; Walsh, Peter J.; Michie, Alison M.; Graham, Gerard J.; Manoharan, Anand; Halsey, Christina; Blyth, Karen; Wolkers, Monika C.; Miller, Crispin; Pennington, Daniel J.; Jones, Gareth W.; Fournie, Jean-Jacques; Bekiaris, Vasileios; Coffelt, Seth B. Share Save
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Activating p53 abolishes self-renewal of quiescent leukaemic stem cells in residual CML disease Scott, Mary T.; Liu, Wei; Mitchell, Rebecca; Clarke, Cassie J.; Kinstrie, Ross; Warren, Felix; Almasoudi, Hassan; Stevens, Thomas; Dunn, Karen; Pritchard, John; Drotar, Mark E.; Michie, Alison M.; Jorgensen, Heather G.; Higgins, Brian; Copland, Mhairi; Vetrie, David Share Save
mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia Malik, Natasha; Hay, Jodie; Almuhanna, Hassan N. B.; Dunn, Karen M.; Lees, Jamie; Cassels, Jennifer; Li, Jiatian; Nakagawa, Rinako; Sansom, Owen J.; Michie, Alison M. Share Save
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Central nervous system involvement in childhood acute lymphoblastic leukemia is linked to upregulation of cholesterol biosynthetic pathways Cousins, A.; Olivares, O.; Markert, E.; Manoharan, A.; Bubnova, X.; Bresolin, S.; Degn, M.; Li, Z.; Silvestri, D.; McGregor, G.; Tumanov, S.; Sumpton, D.; Kamphorst, J. J.; Michie, A. M.; Herzyk, P.; Valsecchi, M. G.; Yeoh, A. E.; Schmiegelow, K.; te Kronnie, G.; Gottlieb, E.; Halsey, C. Share Save
ULK1 inhibition promotes oxidative stress-induced differentiation and sensitizes leukemic stem cells to targeted therapy Ianniciello, Angela; Zarou, Martha M.; Rattigan, Kevin M.; Scott, Mary; Dawson, Amy; Dunn, Karen; Brabcova, Zuzana; Kalkman, Eric R.; Nixon, Colin; Michie, Alison M.; Copland, Mhairi; Vetrie, David; Ambler, Martin; Saxty, Barbara; Helgason, G. Vignir Share Save
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A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival Massett, Matthew E.; Monaghan, Laura; Patterson, Shaun; Mannion, Niamh; Bunschoten, Roderick P.; Hoose, Alex; Marmiroli, Sandra; Liskamp, Robert M. J.; Jorgensen, Heather G.; Vetrie, David; Michie, Alison M.; Huang, Xu Share Save
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AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival Cosimo, Emilio; Tarafdar, Anuradha; Moles, Michael W.; Holroyd, Ailsa K.; Malik, Natasha; Catherwood, Mark A.; Hay, Jodie; Dunn, Karen M.; Macdonald, Alanm.; Guichard, SylvieM.; O'Rourke, Declan; Leach, Michael T.; Sansom, Owen J.; Cosulich, Sabina C.; McCaig, Alison M.; Michie, Alison M. Share Save
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors Baquero, Pablo; Dawson, Amy; Mukhopadhyay, Arunima; Kuntz, Elodie M.; Mitchell, Rebecca; Olivares, Orianne; Lanniciello, Angela; Scott, Mary T.; Dunn, Karen; Nicastri, Michael C.; Winkler, Jeffrey D.; Michie, Alison M.; Ryan, Kevin M.; Halsey, Christina; Gottlieb, Eyal; Keaney, Erin P.; Murphy, Leon O.; Amaravadi, Ravi K.; Holyoake, Tessa L.; Helgason, G. Vignir Share Save
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Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes Nakagawa, Rinako; Vukovic, Milica; Tarafdar, Anuradha; Cosimo, Emilio; Dunn, Karen; McCaig, Alison M.; Holroyd, Ailsa; McClanahan, Fabienne; Ramsay, Alan G.; Gribben, John G.; Michie, Alison M. Share Save
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