Not logged in The age of adult pilocytic astrocytoma cells Voronina, Natalia; Aichmueller, Christian; Kolb, Thorsten; Korshunov, Andrey; Ryzhova, Marina; Barnholtz-Sloan, Jill; Cioffi, Gino; Sill, Martin; von Deimling, Andreas; Pfister, Stefan M.; Gronych, Jan; Jones, David T. W.; Frisen, Jonas; Zapatka, Marc; Ernst, Aurelie Share Save
DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas Schramm, Kathrin; Iskar, Murat; Statz, Britta; Jaeger, Natalie; Haag, Daniel; Slabicki, Mikolaj; Pfister, Stefan M.; Zapatka, Marc; Gronych, Jan; Jones, David T. W.; Lichter, Peter Share Save
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Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors Bayindir-Buchhalter, Irem; Wolff, Gretchen; Lerch, Sarah; Sijmonsma, Tjeerd; Schuster, Maximilian; Gronych, Jan; Billeter, Adrian T.; Babaei, Rohollah; Krunic, Damir; Ketscher, Lars; Spielmann, Nadine; de Angelis, Martin Hrabe; Ruas, Jorge L.; Mueller-Stich, Beat P.; Heikenwalder, Mathias; Lichter, Peter; Herzig, Stephan; Vegiopoulos, Alexandros Share Save
Somatic CRISPR/Cas9-mediated gene editing enables versatile brain tumor modeling Zuckermann, Marc; Ismer, Britta; Hovestadt, Volker; Knobbe-Thomsen, Christiane B.; Zapatka, Marc; Northcott, Paul A.; Roussel, Martine F.; Reifenberger, Guido; Lichter, Peter; Pfister, Stefan M.; Kawauchi, Daisuke; Gronych, Jan; Jones, David T. Share Save
Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells Kawauchi, D.; Ogg, R. J.; Liu, L.; Shih, D. J. H.; Finkelstein, D.; Murphy, B. L.; Rehg, J. E.; Korshunov, A.; Calabrese, C.; Zindy, F.; Phoenix, T.; Kawaguchi, Y.; Gronych, J.; Gilbertson, R. J.; Lichter, P.; Gajjar, A.; Kool, M.; Northcott, P. A.; Pfister, S. M.; Roussel, M. F. Share Save
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme Feng, Weijun; Kawauchi, Daisuke; Koerkel-Qu, Huiqin; Deng, Huan; Serger, Elisabeth; Sieber, Laura; Ariel Lieberman, Jenna; Jimeno-Gonzalez, Silvia; Lambo, Sander; Hanna, Bola S.; Harim, Yassin; Jansen, Malin; Neuerburg, Anna; Friesen, Olga; Zuckermann, Marc; Rajendran, Vijayanad; Gronych, Jan; Ayrault, Olivier; Korshunov, Andrey; Jones, David T. W.; Kool, Marcel; Northcott, Paul A.; Lichter, Peter; Cortes-Ledesma, Felipe; Pfister, Stefan M.; Liu, Hai-Kun Share Save
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma Bender, Sebastian; Gronych, Jan; Warnatz, Hans-Joerg; Hutter, Barbara; Groebner, Susanne; Ryzhova, Marina; Pfaff, Elke; Hovestadt, Volker; Weinberg, Florian; Halbach, Sebastian; Kool, Marcel; Northcott, Paul A.; Sturm, Dominik; Bjerke, Lynn; Zichner, Thomas; Stutz, Adrian M.; Schramm, Kathrin; Huang, Bingding; Buchhalter, Ivo; Heinold, Michael; Risch, Thomas; Worst, Barbara C.; van Tilburg, Cornelis M.; Weber, Ursula D.; Zapatka, Marc; Raeder, Benjamin; Milford, David; Heiland, Sabine; von Kalle, Christof; Previti, Christopher; Lawerenz, Chris; Kulozik, Andreas E.; Unterberg, Andreas; Witt, Olaf; von Deimling, Andreas; Capper, David; Truffaux, Nathalene; Grill, Jacques; Jabado, Nada; Sehested, Astrid M.; Sumerauer, David; Hmida-Ben Brahim, Dorra; Trabelsi, Saoussen; Ng, Ho-Keung; Zagzag, David; Allen, Jeffrey C.; Karajannis, Matthias A.; Gottardo, Nicholas G.; Jones, Chris; Korbel, Jan; Schmidt, Sabine; Wolf, Stephan; Reifenberger, Guido; Felsberg, Jorg; Brors, Benedikt; Herold-Mende, Christel; Lehrach, Hans; Brummer, Tilman; Korshunov, Andrey; Eils, Roland; Yaspo, Marie-Laure; Pfister, Stefan M.; Lichter, Peter; Jones, David T. W. Share Save
TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus Senis, Elena; Mockenhaupt, Stefan; Rupp, Daniel; Bauer, Tobias; Paramasivam, Nagarajan; Knapp, Bettina; Gronych, Jan; Grosse, Stefanie; Windisch, Marc P.; Schmidt, Florian; Theis, Fabian J.; Eils, Roland; Lichter, Peter; Schlesner, Matthias; Bartenschlager, Ralf; Grimm, Dirk Share Save
Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling Zuckermann, Marc; Hovestadt, Volker; Knobbe-Thomsen, Christiane B.; Zapatka, Marc; Northcott, Paul A.; Schramm, Kathrin; Belic, Jelena; Jones, David T. W.; Tschida, Barbara; Moriarity, Branden; Largaespada, David; Roussel, Martine F.; Korshunov, Andrey; Reifenberger, Guido; Pfister, Stefan M.; Lichter, Peter; Kawauchi, Daisuke; Gronych, Jan Share Save
Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling Zuckermann, Marc; Hovestadt, Volker; Knobbe-Thomsen, Christiane B.; Zapatka, Marc; Northcott, Paul A.; Schramm, Kathrin; Belic, Jelena; Jones, David T. W.; Tschida, Barbara; Moriarity, Branden; Largaespada, David; Roussel, Martine F.; Korshunov, Andrey; Reifenberger, Guido; Pfister, Stefan M.; Lichter, Peter; Kawauchi, Daisuke; Gronych, Jan Share Save
Targeting Self-Renewal in High-Grade Brain Tumors Leads to Loss of Brain Tumor Stem Cells and Prolonged Survival Zhu, Zhe; Khan, Muhammad Amir; Weiler, Markus; Blaes, Jonas; Jestaedt, Leonie; Geibert, Madeleine; Zou, Peng; Gronych, Jan; Bernhardt, Olga; Korshunov, Andrey; Bugner, Verena; Lichter, Peter; Radlwimmer, Bernhard; Heiland, Sabine; Bendszus, Martin; Wick, Wolfgang; Liu, Hai-Kun Share Save
Suppression of proinvasive RGS4 by mTOR inhibition optimizes glioma treatment Weiler, M.; Pfenning, P-N; Thiepold, A-L; Blaes, J.; Jestaedt, L.; Gronych, J.; Dittmann, L. M.; Berger, B.; Jugold, M.; Kosch, M.; Combs, S. E.; von Deimling, A.; Weller, M.; Bendszus, M.; Platten, M.; Wick, W. Share Save
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Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro Dittmann, L. M.; Danner, A.; Gronych, J.; Wolter, M.; Stuehler, K.; Grzendowski, M.; Becker, N.; Bageritz, J.; Goidts, V.; Toedt, G.; Felsberg, J.; Sabel, M. C.; Barbus, S.; Reifenberger, G.; Lichter, P.; Tews, B. Share Save
Activated BRAF induces pilocytic astrocytomas in mice Gronych, Jan; Korshunov, Andrey; Bageritz, Josephine; Milde, Till; Jugold, Manfred; Jones, David T.; Hambardzumyan, Dolores; Remke, Marc; Hartmann, Christian; Witt, Hendrik; Witt, Olaf; Heiland, Sabine; Bendszus, Martin; Holland, Eric C.; Pfister, Stefan; Lichter, Peter Share Save
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice Gronych, Jan; Korshunov, Andrey; Bageritz, Josephine; Milde, Till; Jugold, Manfred; Hambardzumyan, Dolores; Remke, Marc; Hartmann, Christian; Witt, Hendrik; Jones, David T. W.; Witt, Olaf; Heiland, Sabine; Bendszus, Martin; Holland, Eric C.; Pfister, Stefan; Lichter, Peter Share Save
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