arrow
Back
T

Thomas Huber

novartis biomedical research, basel, switzerland

39H-index
158Paper Count
5.3KCitation Count
Published Papers 75
Publication Date
IL-17A complexes with therapeutic antibodies exhibit distinct size distributions, potentially contributing to clinically observed immunogenicity
errmAbs
IF7.3
err2025-10-19
err0
errOAAI
errDennis Ungan; Céline Be; Paulina Baczyk; Simon Mittermeier; Sylvie Lehmann; Christian Wiesmann; Thomas Huber; Frank Kolbinger; Jean-Michel Rondeau
errShare
errSave
Membrane protein hydration bridges polymer physics and biology
err2025-09-17
err0
PREAI
errC.Swathi K. Menon; Thomas Huber; Lauren E. Thaller; Andrey V. Struts; Evelyn W. Cheng; Zachary T. Bachler; Suchithranga M.D.C Perera; Thomas P. Sakmar; Michael F. Brown
errShare
errSave
errShare
errSave
The role of signaling pathways mediated by the GPCRs CysLTR1/2 in melanocyte proliferation and senescence
err2024-09-17
err0
PREAI
errHuber, Thomas; Horioka-Duplix, Mizuho; Chen, Yuanhuang; Saca, Victoria R.; Ceraudo, Emilie; Chen, Yu; Sakmar, Thomas P.
errShare
errSave
Redirecting an anti-IL-1β antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A
err2023-09-29
err0
errOAAI
errFischman, Sharon; Levin, Itay; Rondeau, Jean-Michel; Strajbl, Marek; Lehmann, Sylvie; Huber, Thomas; Nimrod, Guy; Cebe, Regis; Omer, Dotan; Kovarik, Jiri; Bernstein, Shmuel; Sasson, Yehezkel; Demishtein, Alik; Shlamkovich, Tomer; Bluvshtein, Olga; Grossman, Noam; Barak-Fuchs, Reut; Zhenin, Michael; Fastman, Yair; Twito, Shir; Vana, Tal; Zur, Nevet; Ofran, Yanay
errShare
errSave
Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins
err2023-05-01
err7
errOAAI
errKotliar, Ilana B.; Ceraudo, Emilie; Kemelmakher-Liben, Kevin; Oren, Deena A.; Lorenzen, Emily; Dodig-Crnkovic, Tea; Horioka-Duplix, Mizuho; Huber, Thomas; Schwenk, Jochen M.; Sakmar, Thomas P.
errShare
errSave
Bioorthogonal Tethering Enhances Drug Fragment Affinity for G Protein-Coupled Receptors in Live Cells
err2023-04-28
err6
errOAAI
errMattheisen, Jordan M.; Limberakis, Chris; Ruggeri, Roger B.; Dowling, Matthew S.; Ende, Christopher W. am; Ceraudo, Emilie; Huber, Thomas; McClendon, Christopher L.; Sakmar, Thomas P.
errShare
errSave
Frizzled BRET sensors based on bioorthogonal labeling of unnatural amino acids reveal WNT-induced dynamics of the cysteine-rich domain
err2021-11-12
err19
errOAAI
errKowalski-Jahn, Maria; Schihada, Hannes; Turku, Ainoleena; Huber, Thomas; Sakmar, Thomas P.; Schulte, Gunnar
errShare
errSave
Principles and practice for SARS-CoV-2 decontamination of N95 masks with UV-C
err2021-07-01
err17
errOAAI
errHuber, Thomas; Goldman, Olivia; Epstein, Alexander E.; Stella, Gianna; Sakmar, Thomas P.
errShare
errSave
Combined Inhibition of Gαq and MEK Enhances Therapeutic Efficacy in Uveal Melanoma
err2021-03-01
err37
errOAAI
errHitchman, Tyler D.; Bayshtok, Gabriella; Ceraudo, Emilie; Moore, Amanda R.; Lee, Cindy; Jia, Ruobing; Wang, Naitao; Pachai, Mohini R.; Shoushtari, Alexander N.; Francis, Jasmine H.; Guan, Youxin; Chen, Juliet; Chang, Matthew T.; Taylor, Barry S.; Sakmar, Thomas P.; Huber, Thomas; Chi, Ping; Chen, Yu
errShare
errSave
Direct evidence that the GPCR CysLTR2 mutant causative of uveal melanoma is constitutively active with highly biased signaling
err2021-01-01
err25
errOAAI
errCeraudo, Emilie; Horioka, Mizuho; Mattheisen, Jordan M.; Hitchman, Tyler D.; Moore, Amanda R.; Kazmi, Manija A.; Chi, Ping; Chen, Yu; Sakmar, Thomas P.; Huber, Thomas
errShare
errSave
Purinergic Receptors Crosstalk with CCR5 to Amplify Ca2+ Signaling
err2020-11-20
err13
errOAAI
errHorioka, Mizuho; Ceraudo, Emilie; Lorenzen, Emily; Sakmar, Thomas P.; Huber, Thomas
errShare
errSave
Playing Tag with Your Favorite GPCR Using CRISPR
err2020-06-01
err1
errOAAI
errHorioka, Mizuho; Huber, Thomas; Sakmar, Thomas P.
errShare
errSave
T cell epitope mapping of secukinumab and ixekizumab in healthy donors
errMABS
IF7.3
err2020-01-10
err28
errOAAI
errSpindeldreher, Sebastian; Karle, Anette; Correia, Evelyne; Tenon, Maxime; Gottlieb, Sascha; Huber, Thomas; Maniere, Bernard; Kolbinger, Frank
errShare
errSave
Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor
err2019-11-01
err24
errOAAI
errGagnon, Laurence; Cao, Yubo; Cho, Aaron; Sedki, Dana; Huber, Thomas; Sakmar, Thomas P.; Laporte, Stephane A.
errShare
errSave
Multiplexed analysis of the secretin-like GPCR-RAMP interactome
err2019-09-06
err58
errOAAI
errLorenzen, Emily; Dodig-Crnkovic, Tea; Kotliar, Ilana B.; Pin, Elisa; Ceraudo, Emilie; Vaughan, Roger D.; Uhlen, Mathias; Huber, Thomas; Schwenk, Jochen M.; Sakmar, Thomas P.
errShare
errSave
High-Affinity Binding of Chemokine Analogs that Display Ligand Bias at the HIV-1 Coreceptor CCR5
err2019-09-01
err11
errOAAI
errRico, Carlos A.; Berchiche, Yamina A.; Horioka, Mizuho; Peeler, Jennifer C.; Lorenzen, Emily; Tian, He; Kazmi, Manija A.; Fuerstenberg, Alexandre; Gaertner, Hubert; Hartley, Oliver; Sakmar, Thomas P.; Hubert, Thomas
errShare
errSave
Third-Party Capture of Elusive GPCR Dimers
err2019-01-01
err1
errOAAI
errHuber, Thomas; Sakmar, Thomas P.
errShare
errSave
G protein subtype-specific signaling bias in a series of CCR5 chemokine analogs
err2018-10-16
err31
PREAI
errLorenzen, Emily; Ceraudo, Emilie; Berchiche, Yamina A.; Rico, Carlos A.; Furstenberg, Alexandre; Sakmar, Thomas P.; Huber, Thomas
errShare
errSave
DNA-encircled lipid bilayers
err2018-01-01
err39
errOAAI
errIric, Katarina; Subramanian, Madhumalar; Oertel, Jana; Agarwal, Nayan P.; Matthies, Michael; Periole, Xavier; Sakmar, Thomas P.; Huber, Thomas; Fahmy, Karim; Schmidt, Thorsten L.
errShare
errSave