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J

John Hardy

university college london

207H-index
1.9KPaper Count
23.8WCitation Count
Published Papers 711
Publication Date
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Large-scale genetic characterization of Parkinson’s disease in the African and African admixed populations
errBrain
IF11.7
err2025-10-08
err0
errOAAI
errFulya Akçimen; Kimberly Paquette; Peter Wild Crea; Kathryn Step; Emily Waldo; Mathew J Koretsky; Paula Saffie-Awad; Charles Achoru; Funmilola Taiwo; Simon Ozomma; Gerald Onwuegbuzie; Marzieh Khani; Spencer Grant; Lukman Owolabi; Chiamaka Okereke; Olajumoke Oshinaike; Emmanuel Iwuozo; Suleyman Can Akerman; Paul Suhwan Lee; Shyngle Oyakhire; Nosakhare Osemwegie; Kensuke Daida; Sani Abubakar; Adedunni Olusanya; Mariam Isayan; Christiane Alvarez; Rami Traurig; Adebimpe Ogunmodede; Sarah Samuel; Mary B Makarious; Fadimatu Sa’ad; Rashidat Olanigan; Kristin Levine; Ewere Marie Ogbimi; Dan Vitale; Francis Odiase; Francis Ojini; Olanike Odeniyi; Zih-Hua Fang; Nkechi Obianozie; Deborah A Hall; Ernest Nwazor; Tao Xie; Francesca Nwaokorie; Mahesh Padmanaban; Paul Nwani; Ejaz A Shamim; Alero Nnama; David Standaert; Morenikeji Komolafe; Marissa Dean; Godwin Osaigbovo; Elizabeth Disbrow; Ismaila Ishola; Ashley Rawls; Frank Imarhiagbe; Shivika Chandra; Cyril Erameh; Vanessa Hinson; Naomi Louie; Ahmed Idowu; J Solle; Scott A Norris; Abdullahi Ibrahim; Camilla Kilbane; Gauthaman Sukumar; Lisa M Shulman; Daniel Ezuduemoih; Julia Staisch; Sarah Breaux; Clifton Dalgard; Erin R Foster; Abiodun Bello; Andrew Ameri; Raquel Real; Erica Ikwenu; Huw R Morris; Roosevelt Anyanwu; Erin Furr Stimming; Kimberley Billingsley; Wemimo Alaofin; Pilar Alvarez Jerez; Osigwe Agabi; Dena G Hernandez; Rufus Akinyemi; Sampath Arepalli; Laksh Malik; Raymond Owolabi; Yakub Nyandaiti; Hampton L Leonard; Kolawole Wahab; Oladunni Abiodun; Carlos F Hernandez; Fatima Abdulai; Hirotaka Iwaki; Soraya Bardien; Christine Klein; John Hardy; Henry Houlden; Kamalini Ghosh Galvelis; Mike A Nalls; Nabila Dahodwala; Whitley Aamodt; Emily Hill; Alberto Espay; Stewart Factor; Chantale Branson; Cornelis Blauwendraat; Andrew B Singleton; Oluwadamilola Ojo; Lana M Chahine; Njideka Okubadejo; Sara Bandres-Ciga; null
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Large-scale visualization of α-synuclein oligomers in Parkinson’s disease brain tissue
errNature Biomedical Engineering
IF26.6
err2025-10-01
err0
errOAAI
errRebecca Andrews; Bin Fu; Christina E. Toomey; Jonathan C. Breiter; Joanne Lachica; Joseph S. Beckwith; Ru Tian; Emma E. Brock; Lisa-Maria Needham; Gregory J. Chant; Camille Loiseau; Angèle Deconfin; Kenza Baspin; Rebeka Popovic; James Evans; Yen Goh; Begüm Kurt; Lenart Senicar; Marisa Edmonds; Tim Bartels; Nora Bengoa-Vergniory; Peter J. Magill; Zane Jaunmuktane; Oliver J. Freeman; Benjamin J. M. Taylor; John Hardy; Tammaryn Lashley; Mina Ryten; Michele Vendruscolo; Nicholas W. Wood; Lucien E. Weiss; Sonia Gandhi; Steven F. Lee
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errSave
Alzheimer's Disease: Treatment Challenges for the Future
errJournal of Neurochemistry
IF4
err2025-07-31
err0
errOAAI
errJohn Hardy
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errSave
Milestone Review: The History of Molecular Genetics Analysis of Alzheimer's Disease
errJournal of Neurochemistry
IF4
err2025-07-02
err0
errOAAI
errJohn Hardy
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errSave
What does heritability of Alzheimer's disease represent? (vol 18, e0281440, 2023)
errPLOS ONE
IF2.6
err2025-05-12
err0
errOAAI
errBaker, Emily; Leonenko, Ganna; Schmidt, Karl Michael; Hill, Matthew; Myers, Amanda J.; Shoai, Maryam; de Rojas, Itziar; Tesi, Niccolo; Holstege, Henne; van der Flier, Wiesje M.; Pijnenburg, Yolande A. L.; Ruiz, Agustin; Hardy, John; van der Lee, Sven; Escott-Price, Valentina
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Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis
errMOLECULAR NEURODEGENERATION
IF17.5
err2025-05-09
err0
errOAAI
errHardy, John; Lewis, Patrick
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The genetics of neurodegenerative diseases is the genetics of age-related damage clearance failure
errMOLECULAR PSYCHIATRY
IF10.1
err2025-01-29
err0
errOAAI
errHardy, J; Escott-Price, V
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Amelioration of signaling deficits underlying metabolic shortfall in TREM2R47H human iPSC-derived microglia
errFEBS JOURNAL
IF4.2
err2024-12-26
err1
errOAAI
errVasilopoulou, Foteini; Piers, Thomas M.; Wei, Jingzhang; Hardy, John; Pocock, Jennifer M.
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African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-12-12
err0
errOAAI
errJerez, Pilar Alvarez; Crea, Peter Wild; Ramos, Daniel M.; Gustavsson, Emil K.; Radefeldt, Mandy; Damianov, Andrey; Makarious, Mary B.; Ojo, Oluwadamilola O.; Billingsley, Kimberley J.; Malik, Laksh; Daida, Kensuke; Bromberek, Sarah; Hu, Fangle; Schneider, Zachary; Surapaneni, Aditya L.; Stadler, Julia; Rizig, Mie; Morris, Huw R.; Pantazis, Caroline B.; Leonard, Hampton L.; Screven, Laurel; Qi, Yue A.; Nalls, Mike A.; Bandres-Ciga, Sara; Hardy, John; Houlden, Henry; Eng, Celeste; Burchard, Esteban Gonzalez; Kachuri, Linda; Lin, Chia-Ho; Black, Douglas L.; Singleton, Andrew B.; Fischer, Steffen; Bauer, Peter; Reed, Xylena; Ryten, Mina; Beetz, Christian; Ward, Michael; Okubadejo, Njideka U.; Blauwendraat, Cornelis
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The ZFHX3 GGC Repeat Expansion Underlying Spinocerebellar Ataxia Type 4 has a Common Ancestral Founder
errMOVEMENT DISORDERS
IF7.6
err2024-12-05
err0
errOAAI
errChen, Zhongbo; Alvarez Jerez, Pilar; Anderson, Claire; Paucar, Martin; Lee, Jasmaine; Nilsson, Daniel; Macpherson, Hannah; Scardamaglia, Annarita; Montgomery, Kylie; Hardy, John; Singleton, Andrew B.; Tucci, Arianna; Mathews, Katherine D.; Fu, Ying-Hui; Engvall, Martin; Laffita-Mesa, Jose; Nennesmo, Inger; Wedell, Anna; Ptacek, Louis J.; Blauwendraat, Cornelis; Gustavsson, Emil K.; Svenningsson, Per; Ryten, Mina; Houlden, Henry
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Elucidating the genomic basis of rare pediatric neurological diseases in Central Asia and Transcaucasia
errNATURE GENETICS
IF31.8
err2024-11-22
err0
PREAI
errKaiyrzhanov, Rauan; Zharkinbekova, Nazira; Guliyeva, Ulviyya; Ganieva, Manizha; Tavadyan, Zaruhi; Gachechiladze, Tamar; Salayev, Kamran; Guliyeva, Sughra; Isayan, Mariam; Kekenadze, Mariam; Sukhudyan, Biayna; Gevorgyan, Ani; Hakobyan, Artsruni; Ibadova, Rima; Tabatadze, Nazi; Kurua, Ekaterina; Shatirishvili, Teona; Yerkhojayeva, Nigara; Koneev, Kairgali; Zhumakhanov, Dauren; Mukushev, Askhat; Jaxybayeva, Altynshash; Nauryzbayeva, Alissa; Isrofilov, Maksudjon; Badalova, Saadat; Zeyniyeva, Naila; Hajiyeva, Ilaha; Alakbarov, Leyla; Zeynalova, Aynur; Chelban, Viorica; Vandrovcova, Jana; Turchetti, Valentina; Murphy, David; Efthymiou, Stephanie; Alavi, Shahryar; Mohammad, Rahema; Tkemaladze, Tinatin; Shashkin, Chingiz; Tatishvili, Nana Nino; Beridze, Maia; Khachatryan, Samson G.; Melikishvili, Gia; Hardy, John; Maroofian, Reza; Houlden, Henry
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Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia
errACTA NEUROPATHOLOGICA
IF9.3
err2024-11-15
err0
errOAAI
errArber, Charles; Casey, Jackie M.; Crawford, Samuel; Rambarack, Naiomi; Yaman, Umran; Wiethoff, Sarah; Augustin, Emma; Piers, Thomas M.; Price, Matthew; Rostagno, Agueda; Ghiso, Jorge; Lewis, Patrick A.; Revesz, Tamas; Hardy, John; Pocock, Jennifer M.; Houlden, Henry; Schott, Jonathan M.; Salih, Dervis A.; Lashley, Tammaryn; Wray, Selina
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errSave
Divisions over the regulation of lecanemab
errLANCET
IF88.5
err2024-11-01
err0
PREAI
errDe Strooper, Bart; Haass, Christian; Hardy, John; Zetterberg, Henrik
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errSave
Assessing clinical progression measures in Alzheimer's disease trials: A systematic review and meta-analysis
errALZHEIMERS & DEMENTIA
IF11.1
err2024-10-22
err0
errOAAI
errMcLaughlin, Jonathan; Scotton, William J.; Ryan, Natalie S.; Hardy, John A.; Shoai, Maryam
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errSave
Increased frequency of repeat expansion mutations across different populations
errNATURE MEDICINE
IF50
err2024-10-01
err3
errOAAI
errIbanez, Kristina; Jadhav, Bharati; Zanovello, Matteo; Gagliardi, Delia; Clarkson, Christopher; Facchini, Stefano; Garg, Paras; Martin-Trujillo, Alejandro; Gies, Scott J.; Deforie, Valentina Galassi; Dalmia, Anupriya; Moss, Davina J. Hensman; Vandrovcova, Jana; Rocca, Clarissa; Moutsianas, Loukas; Marini-Bettolo, Chiara; Walker, Helen; Turner, Chris; Shoai, Maryam; Long, Jeffrey D.; Fratta, Pietro; Langbehn, Douglas R.; Tabrizi, Sarah J.; Caulfield, Mark J.; Cortese, Andrea; Escott-Price, Valentina; Hardy, John; Houlden, Henry; Sharp, Andrew J.; Tucci, Arianna
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NeuroBooster Array: A Genome-Wide Genotyping Platform to Study Neurological Disorders Across Diverse Populations
errMOVEMENT DISORDERS
IF7.6
err2024-09-16
err4
errOAAI
errBandres-Ciga, Sara; Faghri, Faraz; Majounie, Elisa; Koretsky, Mathew J.; Kim, Jeffrey; Levine, Kristin S.; Leonard, Hampton; Makarious, Mary B.; Iwaki, Hirotaka; Crea, Peter Wild; Hernandez, Dena G.; Arepalli, Sampath; Billingsley, Kimberley; Lohmann, Katja; Klein, Christine; Lubbe, Steven J.; Jabbari, Edwin; Saffie-Awad, Paula; Narendra, Derek; Reyes-Palomares, Armando; Quinn, John P.; Schulte, Claudia; Morris, Huw R.; Traynor, Bryan J.; Scholz, Sonja W.; Houlden, Henry; Hardy, John; Dumanis, Sonya; Riley, Ekemini; Blauwendraat, Cornelis; Singleton, Andrew; Nalls, Mike; Jeff, Janina; Vitale, Dan
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Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes
errNATURE COMMUNICATIONS
IF15.7
err2024-09-09
err0
errOAAI
errFarrell, Kurt; Humphrey, Jack; Chang, Timothy; Zhao, Yi; Leung, Yuk Yee; Kuksa, Pavel P.; Patil, Vishakha; Lee, Wan-Ping; Kuzma, Amanda B.; Valladares, Otto; Cantwell, Laura B.; Wang, Hui; Ravi, Ashvin; De Sanctis, Claudia; Han, Natalia; Christie, Thomas D.; Afzal, Robina; Kandoi, Shrishtee; Whitney, Kristen; Krassner, Margaret M.; Ressler, Hadley; Kim, SoongHo; Dangoor, Diana; Iida, Megan A.; Casella, Alicia; Walker, Ruth H.; Nirenberg, Melissa J.; Renton, Alan E.; Babrowicz, Bergan; Coppola, Giovanni; Raj, Towfique; Hoeglinger, Guenter U.; Mueller, Ulrich; Golbe, Lawrence I.; Morris, Huw R.; Hardy, John; Revesz, Tamas; Warner, Tom T.; Jaunmuktane, Zane; Mok, Kin Y.; Rademakers, Rosa; Dickson, Dennis W.; Ross, Owen A.; Wang, Li-San; Goate, Alison; Schellenberg, Gerard; Geschwind, Daniel H.; Crary, John F.; Naj, Adam
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Chromosome X-wide association study in case control studies of pathologically confirmed Alzheimer's disease in a European population
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2024-09-04
err2
errOAAI
errSimmonds, Emily; Leonenko, Ganna; Yaman, Umran; Bellou, Eftychia; Myers, Amanda; Morgan, Kevin; Brookes, Keeley; Hardy, John; Salih, Dervis; Escott-Price, Valentina
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Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models (vol 42, e113246, 2023)
errEMBO JOURNAL
IF8.3
err2024-07-31
err0
errOAAI
errRueda-Carrasco, Javier; Sokolova, Dimitra; Lee, Sang-Eun; Childs, Thomas; Jurcakova, Natalia; Crowley, Gerard; De Schepper, Sebastiaan; Ge, Judy Z.; Lachica, Joanne, I; Toomey, Christina E.; Freeman, Oliver J.; Hardy, John; Barnes, Samuel J.; Lashley, Tammaryn; Stevens, Beth; Chang, Sunghoe; Hong, Soyon
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errSave
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
errAMERICAN JOURNAL OF HUMAN GENETICS
IF8.1
err2024-07-01
err0
errOAAI
errManzoni, Claudia; Kia, Demis A.; Ferrari, Raffaele; Leonenko, Ganna; Costa, Beatrice; Saba, Valentina; Jabbari, Edwin; Tan, Manuela M. X.; Albani, Diego; Alvarez, Victoria; Alvarez, Ignacio; Andreassen, Ole A.; Angiolillo, Antonella; Arighi, Andrea; Baker, Matt; Benussi, Luisa; Bessi, Valentina; Binetti, Giuliano; Blackburn, Daniel J.; Boada, Merce; Boeve, Bradley F.; Borrego-Ecija, Sergi; Borroni, Barbara; Brathen, Geir; Brooks, William S.; Bruni, Amalia C.; Caroppo, Paola; Bandres-Ciga, Sara; Clarimon, Jordi; Colao, Rosanna; Cruchaga, Carlos; Danek, Adrian; de Boer, Sterre C. M.; de Rojas, Itziar; di Costanzo, Alfonso; Dickson, Dennis W.; Diehl-Schmid, Janine; Dobson-Stone, Carol; Dols-Icardo, Oriol; Donizetti, Aldo; Dopper, Elise; Durante, Elisabetta; Ferrari, Camilla; Forloni, Gianluigi; Frangipane, Francesca; Fratiglioni, Laura; Kramberger, Milica G.; Galimberti, Daniela; Gallucci, Maurizio; Garcia-Gonzalez, Pablo; Ghidoni, Roberta; Giaccone, Giorgio; Graff, Caroline; Graff-Radford, Neill R.; Grafman, Jordan; Halliday, Glenda M.; Hernandez, Dena G.; Hjermind, Lena E.; Hodges, John R.; Holloway, Guy; Huey, Edward D.; Illan-Gala, Ignacio; Josephs, Keith A.; Knopman, David S.; Kristiansen, Mark; Kwok, John B.; Leber, Isabelle; Leonard, Hampton L.; Libri, Ilenia; Lleo, Alberto; Mackenzie, Ian R.; Madhan, Gaganjit K.; Maletta, Raffaele; Marquie, Marta; Maver, Ales; Menendez-Gonzalez, Manuel; Milan, Graziella; Miller, Bruce L.; Morris, Christopher M.; Morris, Huw R.; Nacmias, Benedetta; Newton, Judith; Nielsen, Jorgen E.; Nilsson, Christer; Novelli, Valeria; Padovani, Alessandro; Pal, Suvankar; Pasquier, Florence; Pastor, Pau; Perneczky, Robert; Peterlin, Borut; Petersen, Ronald C.; Piguet, Olivier; Pijnenburg, Yolande A. L.; Puca, Annibale A.; Rademakers, Rosa; Rainero, Innocenzo; Reus, Lianne M.; Richardson, Anna M. T.; Riemenschneider, Matthias; Rogaeva, Ekaterina; Rogelj, Boris; Rollinson, Sara; Rosen, Howard; Rossi, Giacomina; Rowe, James B.; Rubino, Elisa; Ruiz, Agustin; Salvi, Erika; Sanchez-Valle, Raquel; Sando, Sigrid Botne; Santillo, Alexander F.; Saxon, Jennifer A.; Schlachetzki, Johannes C. M.; Scholz, Sonja W.; Seelaar, Harro; Seeley, William W.; Serpente, Maria; Sorbi, Sandro; Sordon, Sabrina; St George-Hyslop, Peter; Thompson, Jennifer C.; Van Broeckhoven, Christine; Van Deerlin, Vivianna M.; Van der Lee, Sven J.; Van Swieten, John; Tagliavini, Fabrizio; van der Zee, Julie; Veronesi, Arianna; Vitale, Emilia; Waldo, Maria Landqvist; Yokoyama, Jennifer S.; Nalls, Mike A.; Momeni, Parastoo; Singleton, Andrew B.; Hardy, John; Escott-Price, Valentina
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Research Directions

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Co-authors
Cooperation Journals
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