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William J. Quinn

university of pennsylvania
H-index:32
Citation Count:5,481
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mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b

mTORC1通过Ppp1r3b控制小鼠餐后肝糖原合成

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-01-301
OAAI
Uehara, Kahealani; Lee, Won Dong; Stefkovich, Megan; Biswas, Dipsikha; Santoleri, Dominic; Whitlock, Anna Garcia; Quinn III, William; Coopersmith, Talia; Creasy, Kate Townsend; Rader, Daniel J.; Sakamoto, Kei; Rabinowitz, Joshua D.; Titchenell, Paul M.
Evolution of KT-A112, an AAVMediated Gene Therapy for the Treatment of Type 1 Diabetes
DIABETES
IF7.5
2023-06-200
PRE
Smith, Chari; Harrington, William W.; Stone, Michele; Karadge, Uma; Liu, Jiewu; Quinn, William J., III; Bassiri, Ashlyn; Mallory, Jason; Jimenez, Veronica; Bosch, Fatima; Rhodes, Melissa
Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX
MOLECULAR AND CELLULAR BIOLOGY
IF2.7
2023-03-2717
OAAI
Perchonock, Claire E.; Fernando, Melissa C.; Quinn, William J., III; Nguyen, Chau T.; Sun, Jing; Shapiro, Michael J.; Shapiro, Virginia Smith
Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood
FRONTIERS IN IMMUNOLOGY
IF5.9
2022-09-1637
OAAI
Smith, Corinne J. J.; Ross, Nikki; Kamal, Ali; Kim, Kevin Y.; Kropf, Elizabeth; Deschatelets, Pascal; Francois, Cedric; Quinn, William J.; Singh, Inderpal; Majowicz, Anna; Mingozzi, Federico; Kuranda, Klaudia
Hepatic expression of GAA results in enhanced enzyme bioavailability in mice and non-human primates
NATURE COMMUNICATIONS
IF15.7
2021-11-0422
OAAI
Costa-Verdera, Helena; Collaud, Fanny; Riling, Christopher R.; Sellier, Pauline; Nordin, Jayme M. L.; Preston, G. Michael; Cagin, Umut; Fabregue, Julien; Barral, Simon; Moya-Nilges, Maryse; Krijnse-Locker, Jacomina; van Wittenberghe, Laetitia; Daniele, Natalie; Gjata, Bernard; Cosette, Jeremie; Abad, Catalina; Simon-Sola, Marcelo; Charles, Severine; Li, Mathew; Crosariol, Marco; Antrilli, Tom; Quinn, William J.; Gross, David A.; Boyer, Olivier; Anguela, Xavier M.; Armour, Sean M.; Colella, Pasqualina; Ronzitti, Giuseppe; Mingozzi, Federico
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
CELL METABOLISM
IF30.9
2021-05-01219
OA
Yu, Deyang; Richardson, Nicole E.; Green, Cara L.; Spicer, Alexandra B.; Murphy, Michaela E.; Flores, Victoria; Jang, Cholsoon; Kasza, Ildiko; Nikodemova, Maria; Wakai, Matthew H.; Tomasiewicz, Jay L.; Yang, Shany E.; Miller, Blake R.; Pak, Heidi H.; Brinkman, Jacqueline A.; Rojas, Jennifer M.; Quinn, William J.; Cheng, Eunhae P.; Konon, Elizabeth N.; Haider, Lexington R.; Finke, Megan; Sonsalla, Michelle; Alexander, Caroline M.; Rabinowitz, Joshua D.; Baur, Joseph A.; Malecki, Kristen C.; Lamming, Dudley W.
Lactate Limits T Cell Proliferation via the NAD(H) Redox State

乳酸通过NAD(H) 氧化还原状态限制T细胞增殖

CELL REPORTS
IF6.9
2020-12-01188
OAAI
Quinn, William J., III; Jiao, Jing; TeSlaa, Tara; Stadanlick, Jason; Wang, Zhonglin; Wang, Liqing; Akimova, Tatiana; Angelin, Alessia; Schafer, Patrick M.; Cully, Michelle D.; Perry, Caroline; Kopinski, Piotr K.; Guo, Lili; Blair, Ian A.; Ghanem, Louis R.; Leibowitz, Michael S.; Hancock, Wayne W.; Moon, Edmund K.; Levine, Matthew H.; Eruslanov, Evgeniy B.; Wallace, Douglas C.; Baur, Joseph A.; Beier, Ulf H.
Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser
ELIFE
IF0
2020-11-1012
OA
Gnanapradeepan, Keerthana; Leu, Julia I-Ju; Basu, Subhasree; Barnoud, Thibaut; Good, Madeline; Lee, Joyce, V; Quinn, William J.; Kung, Che-Pei; Ahima, Rexford; Baur, Joseph A.; Wellen, Kathryn E.; Liu, Qin; Schug, Zachary T.; George, Donna L.; Murphy, Maureen E.
Preclinical development of SPK-3006, an investigational liver-directed AAV gene therapy for the treatment of Pompe disease
MOLECULAR GENETICS AND METABOLISM
IF3.5
2020-02-010
PREAI
Armour, Sean M.; Nordin, Jayme M. L.; Verdera, Helena Costa; Sellier, Pauline; Preston, George M.; Riling, Christopher; Cohen, Daniel M.; Collaud, Fanny; Crosariol, Marco; Quinn, William J.; Hanby, Hayley; Cagin, Umut; Puzzo, Francesco; Haurigot, Virginia; Ronzitti, Giuseppe; Colella, Pasqualina; Anguela, Xavier M.; Mingozzi, Federico
Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions

Interleukin-15受体 α 消融对体内等距肌肉收缩模拟的中等运动代谢反应的影响

FRONTIERS IN PHYSIOLOGY
IF3.4
2019-11-266
OAAI
Loro, Emanuele; Jang, Cholsoon; Quinn, William J., III; Baur, Joseph A.; Arany, Zoltan P.; Khurana, Tejvir S.
The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis

骨骼肌Akt在调节肌肉质量和葡萄糖稳态中的作用

MOLECULAR METABOLISM
IF6.6
2019-10-01129
OAAI
Jaiswal, N.; Gavin, M. G.; Quinn, W. J., III; Luongo, T. S.; Gelfer, R. G.; Baur, J. A.; Titchenell, P. M.
The African-specific S47 variant of the p53 tumor suppressor gene alters cell metabolism
CANCER RESEARCH
IF16.6
2019-07-010
PRE
Gnanapradeepan, Keerthana; Basu, Subhasree; Kung, Che-Pei; Barnoud, Thibaut; Good, Madeline; Quinn, William; Lee, Joyce; Wellen, Kathryn; Schug, Zachary; Baur, Joseph; George, Donna; Murphy, Maureen
Blockade of MCU-Mediated Ca2+ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation
CELL REPORTS
IF6.9
2019-03-0177
OAAI
Tomar, Dhanendra; Jana, Fabian; Dong, Zhiwei; Quinn, William J., III; Jadiya, Pooja; Breves, Sarah L.; Daw, Cassidy C.; Srikantan, Subramanya; Shanmughapriya, Santhanam; Nemani, Neeharika; Carvalho, Edmund; Tripathi, Aparna; Worth, Alison M.; Zhang, Xueqian; Razmpour, Roshanak; Seelam, Ajay; Rhode, Stephen; Mehta, Anuj, V; Murray, Michael; Slade, Daniel; Ramirez, Servio H.; Mishra, Prashant; Gerhard, Glenn S.; Caplan, Jeffrey; Norton, Luke; Sharma, Kumar; Rajan, Sudarsan; Balciunas, Darius; Wijesinghe, Dayanjan S.; Ahima, Rexford S.; Baur, Joseph A.; Madesh, Muniswamy
Oral nitrite restores age-dependent phenotypes in eNOS-null mice
JCI INSIGHT
IF6.1
2018-08-239
OA
Tenopoulou, Margarita; Doulias, Paschalis-Thomas; Nakamoto, Kent; Berrios, Kiara; Zura, Gabriella; Li, Chenxi; Faust, Michael; Yakovishina, Veronika; Evans, Perry; Tan, Lu; Bennett, Michael J.; Snyder, Nathaniel W.; Quinn, William J., III; Baur, Joseph A.; Atochin, Dmitriy N.; Huang, Paul L.; Ischiropoulos, Harry
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

NAD合成击穿通量的定量分析

CELL METABOLISM
IF30.9
2018-05-01399
OAAI
Liu, Ling; Su, Xiaoyang; Quinn, William J., III; Hui, Sheng; Krukenberg, Kristin; Frederick, David W.; Redpath, Philip; Zhan, Le; Chellappa, Karthikeyani; White, Eileen; Migaud, Marie; Mitchison, Timothy J.; Baur, Joseph A.; Rabinowitz, Joshua D.
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2017-10-1676
OA
Quinn, William J., III; Wan, Min; Shewale, Swapnil V.; Gelfer, Rebecca; Rader, Daniel J.; Birnbaum, Morris J.; Titchenell, Paul M.
Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments

Foxp3重新编程T细胞代谢以在低葡萄糖，高乳酸环境中发挥作用

CELL METABOLISM
IF30.9
2017-06-01841
OAAI
Angelin, Alessia; Gil-de-Gomez, Luis; Dahiya, Satinder; Jiao, Jing; Guo, Lili; Levine, Matthew H.; Wang, Zhonglin; Quinn, William J., III; Kopinski, Piotr K.; Wang, Liqing; Akimova, Tatiana; Liu, Yujie; Bhatti, Tricia R.; Han, Rongxiang; Laskin, Benjamin L.; Baur, Joseph A.; Blair, Ian A.; Wallace, Douglas C.; Hancock, Wayne W.; Beier, Ulf H.
T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow
CELL REPORTS
IF6.9
2017-02-0197
OAAI
Zaretsky, Arielle Glatman; Konradt, Christoph; Depis, Fabien; Wing, James B.; Goenka, Radhika; Atria, Daniela Gomez; Silver, Jonathan S.; Cho, Sunglim; Wolf, Amaya I.; Quinn, William J.; Engiles, Julie B.; Brown, Dorothy C.; Beiting, Daniel; Erikson, Jan; Allman, David; Cancro, Michael P.; Sakaguchi, Shimon; Lu, Li-Fan; Benoist, Christophe O.; Hunter, Christopher A.
Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production
CELL METABOLISM
IF30.9
2016-06-01238
OAAI
Titchenell, Paul M.; Quinn, William J.; Lu, Mingjian; Chu, Qingwei; Lu, Wenyun; Li, Changhong; Chen, Helen; Monks, Bobby R.; Chen, Julia; Rabinowitz, Joshua D.; Birnbaum, Morris J.
YY1 controls lgκ repertoire and B-cell development, and localizes with condensin on the Igκ locus
EMBO JOURNAL
IF8.3
2013-03-2665
OA
Pan, Xuan; Papasani, Madhusudhan; Hao, Yi; Calamito, Marco; Wei, Fang; Quinn, William J., III; Basu, Arindam; Wang, Junwen; Hodawadekar, Suchita; Zaprazna, Kristina; Liu, Huifei; Shi, Yang; Allman, David; Cancro, Michael; Atchison, Michael L.

Research Directions

The data has not been retrieved yet.
M
Michael P. Cancro
H-index:63Papers:233Citations:1.2万
J
Joseph A. Baur
H-index:73Papers:241Citations:3.3万
D
David Allman
H-index:0Papers:1Citations:0
R
Radhika Goenka
H-index:19Papers:25Citations:1,631
P
Paul M. Titchenell
H-index:26Papers:80Citations:4,053
J
Joshua D. Rabinowitz
H-index:127Papers:777Citations:7.1万
J
Jean L. Scholz
H-index:17Papers:45Citations:2,062
J
Jenni E. Crowley
H-index:8Papers:20Citations:435
M
Morris J. Birnbaum
H-index:109Papers:315Citations:5.1万
J
Jason Stadanlick
H-index:25Papers:98Citations:2,438