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T

Tom W. Claydon

Simon Fraser University

21H-index
81Paper Count
1.4KCitation Count
Published Papers 43
Publication Date
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Electrophysiological Phenotyping of hiPSC-Derived Atrial Cardiomyocytes Using Automated Patch-Clamp: A Platform for Studying Atrial Inherited Arrhythmias
errCells 2025, Vol. 14, Page 1941
IF5.2
err2025-12-06
err0
errOAAI
errVerónica Jiménez-Sábado; Hosna Babini; Peter C. Ruben; Eric A. Accili; Thomas W. Claydon; Leif Hove-Madsen; Glen F. Tibbits
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Development of an Absolute Quantification Method for hERG Using PRM with Single Isotopologue in-Sample Calibration
errACS OMEGA
IF4.3
err2024-07-25
err0
errOAAI
errChang, Ge; Aroge, Fabusuyi A.; Venkateshappa, Ravichandra; Claydon, Tom W.; Sun, Bingyun
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errSave
Ion channel model reduction using manifold boundaries
errJOURNAL OF THE ROYAL SOCIETY INTERFACE
IF3.5
err2022-08-10
err4
errOAAI
errWhittaker, Dominic G.; Wang, Jiahui; Shuttleworth, Joseph G.; Venkateshappa, Ravichandra; Kemp, Jacob M.; Claydon, Thomas W.; Mirams, Gary R.
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Electrophysiological characterization of the hERG R56Q LQTS variant and targeted rescue by the activator RPR260243
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2021-08-16
err8
errOAAI
errKemp, Jacob M.; Whittaker, Dominic G.; Venkateshappa, Ravichandra; Pang, ZhaoKai; Johal, Raj; Sergeev, Valentine; Tibbits, Glen F.; Mirams, Gary R.; Claydon, Thomas W.
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errSave
Utility of Zebrafish Models of Acquired and Inherited Long QT Syndrome
errFRONTIERS IN PHYSIOLOGY
IF3.4
err2021-01-15
err8
errOAAI
errSimpson, Kyle E.; Venkateshappa, Ravichandra; Pang, Zhao Kai; Faizi, Shoaib; Tibbits, Glen F.; Claydon, Tom W.
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errSave
Extracellular protons accelerate hERG channe deactivation by destabilizing voltage sensor relaxation
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2018-12-07
err18
errOAAI
errShi, Yu Patrick; Thouta, Samrat; Cheng, Yen May; Claydon, Tom W.
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errSave
Investigating the state dependence of drug binding in hERG channels using a trapped-open channel phenotype
errSCIENTIFIC REPORTS
IF3.9
err2018-03-21
err9
errOAAI
errThouta, Samrat; Lo, Garman; Grajauskas, Lukas; Claydon, Tom
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Comparison of hERG and zERG Potassium Channel Function and Pharmacology
errBIOPHYSICAL JOURNAL
IF3.1
err2018-02-01
err0
errOAAI
errHull, Christina M.; Genge, Christine E.; Tibbits, Glen F.; Claydon, Thomas W.
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errSave
Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker
errBIOPHYSICAL JOURNAL
IF3.1
err2017-01-01
err12
errOAAI
errThouta, Samrat; Hull, Christina M.; Shi, Yu Patrick; Sergeev, Valentine; Young, James; Cheng, Yen M.; Claydon, Thomas W.
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errSave
Polyunsaturated fatty acids inhibit Kv1.4 by interacting with positively charged extracellular pore residues
errAMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
IF4.7
err2016-08-01
err8
errOAAI
errFarag, N. E.; Jeong, D.; Claydon, T.; Warwicker, J.; Boyett, M. R.
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errSave
NS1643 Interacts around L529 of hERG to Alter Voltage Sensor Movement on the Path to Activation
errBIOPHYSICAL JOURNAL
IF3.1
err2015-03-01
err27
errOAAI
errGuo, Jiqing; Cheng, Yen May; Lees-Miller, James P.; Perissinotti, Laura L.; Claydon, Tom W.; Hull, Christina M.; Thouta, Samrat; Roach, Daniel E.; Durdagi, Serdar; Noskov, Sergei Y.; Duff, Henry J.
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errSave
External Protons Destabilize the Relaxed State of the hERG Channel Voltage Sensor
errBIOPHYSICAL JOURNAL
IF3.1
err2015-01-01
err1
PREAI
errShi, Yu Patrick; Thouta, Samrat; Cheng, Yen May; Claydon, Tom W.
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errSave
Time-Dependent Voltage Sensor Relaxation in hERG Channels
errBIOPHYSICAL JOURNAL
IF3.1
err2015-01-01
err0
errOAAI
errThouta, Samrat; Shi, Yu Patrick; Sokolov, Stanislav; Cheng, Yen May; Claydon, Tom W.
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errSave
Closed-state inactivation induced in KV1 channels by extracellular acidification
errCHANNELS
IF3.2
err2014-10-27
err7
errOAAI
errClaydon, Thomas W.; Kehl, Steven J.; Fedida, David
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errSave
Pro line Scan of the hERG Channel S6 Helix Reveals the Location of the Intracellular Pore Gate
errBIOPHYSICAL JOURNAL
IF3.1
err2014-03-01
err29
errOAAI
errThouta, Samrat; Sokolov, Stanislav; Abe, Yuki; Clark, Sheldon J.; Cheng, Yen M.; Claydon, Tom W.
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errSave
Functional interactions of voltage sensor charges with an S2 hydrophobic plug in hERG channels
errJOURNAL OF GENERAL PHYSIOLOGY
IF2.9
err2013-08-26
err24
errOAAI
errCheng, Yen May; Hull, Christina M.; Niven, Christine M.; Qi, Ji; Allard, Charlene R.; Claydon, Tom W.
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errSave
Extracellular Protons Inhibit Charge Immobilization in the Cardiac Voltage-Gated Sodium Channel
errBIOPHYSICAL JOURNAL
IF3.1
err2013-07-01
err12
errOAAI
errJones, D. K.; Claydon, T. W.; Ruben, P. C.
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errSave
Proton Sensors in the Pore Domain of the Cardiac Voltage-gated Sodium Channel
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2013-02-01
err24
errOAAI
errJones, David K.; Peters, Colin H.; Allard, Charlene R.; Claydon, Tom W.; Ruben, Peter C.
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errSave
A Proline Scan Approach to Investigate the Activation Gate of hERG Channels
errBIOPHYSICAL JOURNAL
IF3.1
err2013-01-01
err0
errOAAI
errThouta, Samrat; Abe, Yuki; Clark, Sheldon; Horsting, Kelsey; Qi, Ji; Claydon, Tom
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errSave
S4-S5 Linker Flexibility Stabilizes hERG Channel Closed States
errBIOPHYSICAL JOURNAL
IF3.1
err2013-01-01
err0
errOAAI
errHull, Christina M.; Van Slyke, Aaron C.; Qi, Ji; Claydon, Tom W.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
C
Colin G. Nichols
H-index: 77 · Papers: 492
M
Mark R. Boyett
H-index: 71 · Papers: 473
V
Vijay Viswanathan
H-index: 67 · Papers: 561
H
Henry J. Duff
H-index: 55 · Papers: 293
D
David Fedida
H-index: 51 · Papers: 365
View more