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Modulation of antigen delivery and lymph node activation in nonhuman primates by saponin adjuvant saponin/monophosphoryl lipid A nanoparticle Yousefpour, Parisa; Zhang, Yiming J.; Maiorino, Laura; Melo, Mariane B.; Arainga Ramirez, Mariluz A.; Kumarapperuma, Sidath C.; Xiao, Peng; Silva, Murillo; Li, Na; Michaels, Katarzyna K.; Georgeson, Erik; Eskandarzadeh, Saman; Kubitz, Michael; Groschel, Bettina; Qureshi, Kashif; Fontenot, Jane; Hangartner, Lars; Nedellec, Rebecca; Love, J. Christopher; Burton, Dennis R.; Schief, William R.; Villinger, Francois J.; Irvine, Darrell J. Share Save
Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii Yang, Yuchen; Dalvie, Neil C.; Brady, Joseph R.; Naranjo, Christopher A.; Lorgeree, Timothy; Rodriguez-Aponte, Sergio A.; Johnston, Ryan S.; Tracey, Mary K.; Elenberger, Carmen M.; Lee, Eric; Tie, Mark; Love, Kerry R.; Love, J. Christopher Share Save
Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to pneumococcal vaccination Morgan, Duncan M.; Zhang, Yiming J.; Kim, Jin-Hwan; Murillo, Maryann; Singh, Suddham; Loschko, Jakob; Surendran, Naveen; Sekulovic, Ognjen; Feng, Ellie; Shi, Shuting; Irvine, Darrell J.; Patil, Sarita U.; Kanevsky, Isis; Chorro, Laurent; Love, J. Christopher Share Save
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CRISPR-Cas9 knockout screen informs efficient reduction of the Komagataella phaffii secretome Dalvie, Neil C.; Lorgeree, Timothy R.; Yang, Yuchen; Rodriguez-Aponte, Sergio A.; Whittaker, Charles A.; Hinckley, Joshua A.; Clark, John J.; Del Rosario, Amanda M.; Love, Kerry R.; Love, J. Christopher Share Save
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Large-Scale Purification and Characterization of Recombinant Receptor-Binding Domain (RBD) of SARS-CoV-2 Spike Protein Expressed in Yeast Nagar, Gaurav; Jain, Siddharth; Rajurkar, Meghraj; Lothe, Rakesh; Rao, Harish; Majumdar, Sourav; Gautam, Manish; Rodriguez-Aponte, Sergio A.; Crowell, Laura E.; Love, J. Christopher; Dandekar, Prajakta; Puranik, Amita; Gairola, Sunil; Shaligram, Umesh; Jain, Ratnesh Share Save
Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018™ Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen Bajoria, Sakshi; Kumru, Ozan S.; Doering, Jennifer; Berman, Katherine; Van Slyke, Greta; Prigodich, Anneka; Rodriguez-Aponte, Sergio A.; Kleanthous, Harry; Love, J. Christopher; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. Share Save
A DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies Tabrizi, Shervin; Martin-Alonso, Carmen; Xiong, Kan; Blewett, Timothy; Sridhar, Sainetra; An, Zhenyi; Patel, Sahil; Rodriguez-Aponte, Sergio; Naranjo, Christopher; Shea, Douglas; Golub, Todd; Bhatia, Sangeeta N.; Adalsteinsson, Viktor A.; Love, J. Christopher Share Save
Minimal purification method enables developability assessment of recombinant proteins Rodriguez-Aponte, Sergio A.; Naranjo, Christopher A.; Johnston, Ryan S.; Dalvie, Neil C.; Crowell, Laura E.; Bajoria, Sakshi; Kumru, Ozan S.; Joshi, Sangeeta B.; Volkin, David B.; Love, J. Christopher Share Save
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer Zagorulya, Maria; Yim, Leon; Morgan, Duncan M.; Edwards, Austin; Torres-Mejia, Elen; Momin, Noor; McCreery, Chloe V.; Zamora, Izabella L.; Horton, Brendan L.; Fox, James G.; Wittrup, K. Dane; Love, J. Christopher; Spranger, Stefani Share Save
Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy LaHood, Nicole A.; Min, Jungki; Keswani, Tarun; Richardson, Crystal M.; Amoako, Kwasi; Zhou, Jingjia; Marini-Rapoport, Orlee; Bernard, Herve; Hazebrouck, Stephane; Shreffler, Wayne G.; Love, J. Christopher; Pomes, Anna; Pedersen, Lars C.; Mueller, Geoffrey A.; Patil, Sarita U. Share Save
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RBD-VLP Vaccines Adjuvanted with Alum or SWE Protect K18-hACE2 Mice against SARS-CoV-2 VOC Challenge Wong, Ting Y.; Russ, Brynnan P.; Lee, Katherine S.; Miller, Olivia A.; Kang, Jason; Cooper, Melissa; Winters, Michael T.; Rodriguez-Aponte, Sergio A.; Dalvie, Neil C.; Johnston, Ryan S.; Rader, Nathaniel A.; Wong, Zeriel Y.; Cyphert, Holly A.; Martinez, Ivan; Shaligram, Umesh; Batwal, Saurabh; Lothe, Rakesh; Chandrasekaran, Rahul; Nagar, Gaurav; Rajurkar, Meghraj; Rao, Harish; Bevere, Justin R.; Barbier, Mariette; Love, J. Christopher; Damron, F. Heath Share Save
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity Hartwell, Brittany L.; Melo, Mariane B.; Xiao, Peng; Lemnios, Ashley A.; Li, Na; Chang, Jason Y. H.; Yu, Jingyou; Gebre, Makda S.; Chang, Aiquan; Maiorino, Laura; Carter, Crystal; Moyer, Tyson J.; Dalvie, Neil C.; Rodriguez-Aponte, Sergio A.; Rodrigues, Kristen A.; Silva, Murillo; Suh, Heikyung; Adams, Josetta; Fontenot, Jane; Love, J. Christopher; Barouch, Dan H.; Villinger, Francois; Ruprecht, Ruth M.; Irvine, Darrell J. Share Save
Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma Grace, Beth E.; Backlund, Coralie M.; Morgan, Duncan M.; Kang, Byong H.; Singh, Nishant K.; Huisman, Brooke D.; Rappazzo, C. Garrett; Moynihan, Kelly D.; Maiorino, Laura; Dobson, Connor S.; Kyung, Taeyoon; Gordon, Khloe S.; Holec, Patrick, V; Mbah, Overbeck C. Takou; Garafola, Daniel; Wu, Shengwei; Love, J. Christopher; Wittrup, K. Dane; Irvine, Darrell J.; Birnbaum, Michael E. Share Save
Antigen-adjuvant interactions, stability, and immunogenicity profiles of a SARS-CoV-2 receptor-binding domain (RBD) antigen formulated with aluminum salt and CpG adjuvants Bajoria, Sakshi; Kaur, Kawaljit; Kumru, Ozan S.; Van Slyke, Greta; Doering, Jennifer; Novak, Hayley; Rodriguez Aponte, Sergio A.; Dalvie, Neil C.; Naranjo, Christopher A.; Johnston, Ryan S.; Silverman, Judith Maxwell; Kleanthous, Harry; Love, J. Christopher; Mantis, Nicholas J.; Joshi, Sangeeta B.; Volkin, David B. Share Save
Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control Gideon, Hannah P.; Hughes, Travis K.; Tzouanas, Constantine N.; Wadsworth, Marc H., II; Tu, Ang Andy; Gierahn, Todd M.; Peters, Joshua M.; Hopkins, Forrest F.; Wei, Jun-Rong; Kummerlowe, Conner; Nargan, Kievershen; Phuah, Jia Yao; Borish, H. Jacob; Maiello, Pauline; White, Alexander G.; Winchell, Caylin G.; Nyquist, Sarah K.; Ganchua, Sharie Keanne C.; Myers, Amy; V. Patel, Kush; Ameel, Cassaundra L.; Cochran, Catherine T.; Ibrahim, Samira; Tomko, Jaime A.; Frye, Lonnie James; Rosenberg, Jacob M.; Shih, Angela; Chao, Michael; Klein, Edwin; Scanga, Charles A.; Ordovas-Montanes, Jose; Berger, Bonnie; Mattila, Joshua T.; Madansein, Rajhmun; Love, J. Christopher; Lin, Philana Ling; Leslie, Alasdair; Behar, Samuel M.; Bryson, Bryan; Flynn, JoAnne L.; Fortune, Sarah M.; Shalek, Alex K. Share Save
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