Not logged in Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury Kim, Han G.; Gauthier, Marie-Pierre L.; Higgs, Aidan; Hernandez, Denise A.; Zhou, Mingqi; Brant, Jason O.; Bacher, Rhonda L.; Darden, Dijoia B.; Wallet, Shannon M.; Mathews, Clayton E.; Moldawer, Lyle L.; Efron, Philip A.; Kladde, Michael P.; Maile, Robert Share Save
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Innate immune training in the neonatal response to sepsis Rincon, Jaimar C.; Wang, Dayuan; Polcz, Valerie E.; Barrios, Evan L.; Dirain, Marvin L.; Ungaro, Ricardo F.; Nacionales, Dina C.; Zeumer-Spataro, Leilani; Xiao, Feifei; Efron, Philip A.; Moldawer, Lyle L.; Cai, Guoshuai; Larson, Shawn D. Share Save
Determining potential immunomodulatory drug efficacy in sepsis using ELISpot Walton, Andrew H.; Mazer, Monty B.; Remy, Kenneth E.; Osborne, Dale F.; Davitt, Ethan B.; Griffith, Thomas S.; Gould, Robert W.; Badovinac, Vladimir P.; Brakenridge, Scott C.; Drewry, Anne M.; Ungaro, Ricardo F.; Rocha, Ivanna L.; Loftus, Tyler J.; Efron, Philip A.; Moldawer, Lyle L.; Caldwell, Charles C. Share Save
Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner (vol 305, 120995, 2025) Vo, Quan; Simon, Zachary D.; Park, Gwoncheol; Nacionales, Dina C.; Gorski, Carmelina; Barrios, Evan L.; Casadesus, Gemma; Efron, Philip A.; Moldawer, Lyle L.; Nagpal, Ravinder; Febo, Marcelo Share Save
Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness Barrios, Evan L.; Balzano-Nogueira, Leandro; Polcz, Valerie E.; Rodhouse, Christine; Leary, Jack R.; Darden, Dijoia B.; Rincon, Jaimar C.; Dirain, Marvin L.; Ungaro, Ricardo; Nacionales, Dina C.; Larson, Shawn D.; Sharma, Ashish; Upchurch, Gilburt; Wallet, Shannon M.; Brusko, Todd M.; Loftus, Tyler J.; Mohr, Alicia M.; Maile, Robert; Bacher, Rhonda; Cai, Guoshuai; Kladde, Michael P.; Mathews, Clayton E.; Moldawer, Lyle L.; Brusko, Maigan A.; Efron, Philip A. Share Save
Severe trauma leads to sustained muscle loss, induced frailty, and distinct temporal changes in myokine and chemokine profiles of older patients Polcz, Valerie E.; Barrios, Evan L.; Cox, Michael C.; Rocha, Ivanna; Liang, Muxuan; Hawkins, Russell B.; Darden, Dijoia; Ungaro, Ricardo; Dirain, Marvin; Mankowski, Robert; Mohr, Alicia M.; Moore, Frederick A.; Moldawer, Lyle L.; Efron, Philip A.; Brakenridge, Scott C.; Loftus, Tyler J. Share Save
Surviving septic patients endotyped with a functional assay demonstrate active immune responses Price, Adam D.; Becker, Ellen R.; Barrios, Evan L.; Mazer, Monty B.; McGonagill, Patrick W.; Bergmann, Christian B.; Goodman, Michael D.; Gould, Robert W.; Rao, Mahil; Polcz, Valerie E.; Kucaba, Tamara A.; Walton, Andrew H.; Miles, Sydney; Xu, Julie; Liang, Muxuan; Loftus, Tyler J.; Efron, Philip A.; Remy, Kenneth E.; Brakenridge, Scott C.; Badovinac, Vladimir P.; Griffith, Thomas S.; Moldawer, Lyle L.; Hotchkiss, Richard S.; Caldwell, Charles C. Share Save
Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation Bellotti, Paolo; Ladd, Zachary; Leroy, Victoria; Su, Gang; Sharma, Shiven; Hartman, Joseph B.; Krebs, Jonathan; Viscardi, Chelsea; Maile, Robert; Moldawer, Lyle L.; Efron, Phillip A.; Sharma, Ashish K.; Upchurch Jr, Gilbert R. Share Save
MerTK-dependent efferocytosis by monocytic-MDSCs mediates resolution ofischemia/reperfusion injury after lung transplant Leroy, Victoria; Kollareth, Denny J. Manual; Tu, Zhenxiao; Valisno, Jeff Arni C.; Woolet-Stockton, Makena; Saha, Biplab; Emtiazjoo, Amir M.; Rackauskas, Mindaugas; Moldawer, Lyle L.; Efron, Philip A.; Cai, Guoshuai; Atkinson, Carl; Upchurch Jr, Gilbert R.; Sharma, Ashish K. Share Save
Persistence and Sexual Dimorphism of Gut Dysbiosis and Pathobiome after Sepsis and Trauma Munley, Jennifer A.; Park, Gwoncheol; Kelly, Lauren S.; Kannan, Kolenkode B.; Mankowski, Robert T.; Casadesus, Gemma; Chakrabarty, Paramita; Wallet, Shannon M.; Maile, Robert; Bible, Letitia E.; Wang, Bo; Moldawer, Lyle L.; Mohr, Alicia M.; Nagpal, Ravinder; Efron, Philip A. Share Save
The post-septic peripheral myeloid compartment reveals unexpected diversity in myeloid-derived suppressor cells Barrios, Evan L.; Leary, Jack R.; Darden, Dijoia B.; Rincon, Jaimar C.; Willis, Micah; Polcz, Valerie E.; Gillies, Gwendolyn S.; Munley, Jennifer A.; Dirain, Marvin L.; Ungaro, Ricardo; Nacionales, Dina C.; Gauthier, Marie-Pierre L.; Larson, Shawn D.; Morel, Laurence; Loftus, Tyler J.; Mohr, Alicia M.; Maile, Robert; Kladde, Michael P.; Mathews, Clayton E.; Brusko, Maigan A.; Brusko, Todd M.; Moldawer, Lyle L.; Bacher, Rhonda; Efron, Philip A. Share Save
The Lipid Intensive Drug Therapy for Sepsis Phase II Pilot Clinical Trial Guirgis, Faheem W.; Black, Lauren Page; Henson, Morgan; Bertrand, Andrew; Devos, Elizabeth; Ferreira, Jason; Gao, Hanzhi; Wu, Samuel S.; Leeuwenburgh, Christiaan; Moldawer, Lyle; Moore, Frederick; Reddy, Srinivasa T. Share Save
Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot Barrios, Evan L.; Mazer, Monty B.; Mcgonagill, Patrick W.; Bergmann, Christian B.; Goodman, Michael D.; Gould, Robert W.; Rao, Mahil; Polcz, Valerie E.; Davis, Ruth J.; Toro, Drew E. Del; Dirain, Marvin L. S.; Dram, Alexandra; Hale, Lucas O.; Heidarian, Mohammad; Kim, Caleb Y.; Kucaba, Tamara A.; Lanz, Jennifer P.; Mccray, Ashley E.; Meszaros, Sandra; Miles, Sydney; Nelson, Candace R.; Rocha, Ivanna L.; Silva, Elvia E.; Ungaro, Ricardo F.; Walton, Andrew H.; Xu, Julie; Zeumer-Spataro, Leilani; Drewry, Anne M.; Liang, Muxuan; Bible, Letitia E.; Loftus, Tyler J.; Turnbull, Isaiah R.; Efron, Philip A.; Remy, Kenneth E.; Brakenridge, Scott C.; Badovinac, Vladimir P.; Griffith, Thomas S.; Moldawer, Lyle L.; Hotchkiss, Richard S.; Caldwell, Charles C. Share Save
Gut mycobiome dysbiosis after sepsis and trauma Park, Gwoncheol; Munley, Jennifer A.; Kelly, Lauren S.; Kannan, Kolenkode B.; Mankowski, Robert T.; Sharma, Ashish; Upchurch, Gilbert; Casadesus, Gemma; Chakrabarty, Paramita; Wallet, Shannon M.; Maile, Robert; Bible, Letitia E.; Wang, Bo; Moldawer, Lyle L.; Mohr, Alicia M.; Efron, Philip A.; Nagpal, Ravinder Share Save
The persistent inflammation, immunosuppression, and catabolism syndrome 10 years later Efron, Philip A.; Brakenridge, Scott C.; Mohr, Alicia M.; Barrios, Evan L.; Polcz, Valerie E.; Anton, Stephen; Ozrazgat-Baslanti, Tezcan; Bihorac, Azra; Guirgis, Faheem; Loftus, Tyler J.; Rosenthal, Martin; Leeuwenburgh, Christian; Mankowski, Robert; Moldawer, Lyle L.; Moore, Frederick A. Share Save
Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study Balch, Jeremy A.; Chen, Uan-, I; Liesenfeld, Oliver; Starostik, Petr; Loftus, Tyler J.; Efron, Philip A.; Brakenridge, Scott C.; Sweeney, Timothy E.; Moldawer, Lyle L. Share Save
Sex, sepsis and the brain: defining the role of sexual dimorphism on neurocognitive outcomes after infection Polcz, Valerie E.; Barrios, Evan L.; Chapin, Benjamin; Price, Catherine C.; Nagpal, Ravinder; Chakrabarty, Paramita; Casadesus, Gemma; Foster, Thomas; Moldawer, Lyle L.; Efron, Philip A. Share Save
Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial Daix, Thomas; Mathonnet, Armelle; Brakenridge, Scott; Dequin, Pierre-Francois; Mira, Jean-Paul; Berbille, Frederique; Morre, Michel; Jeannet, Robin; Blood, Teresa; Unsinger, Jacqueline; Blood, Jane; Walton, Andrew; Moldawer, Lyle L.; Hotchkiss, Richard; Francois, Bruno Share Save