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Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs Lumeau, Audrey; Bery, Nicolas; Frances, Audrey; Gayral, Marion; Labrousse, Guillaume; Ribeyre, Cyril; Lopez, Charlene; Nevot, Adele; El Kaoutari, Abdessamad; Hanoun, Naima; Sarot, Emeline; Perrier, Marion; Pont, Frederic; Cerapio, Juan-Pablo; Fournie, Jean-Jacques; Lopez, Frederic; Madrid-Mencia, Miguel; Pancaldi, Vera; Pillaire, Marie-Jeanne; Bergoglio, Valerie; Torrisani, Jerome; Dusetti, Nelson; Hoffmann, Jean-Sebastien; Buscail, Louis; Lutzmann, Malik; Cordelier, Pierre Share Save
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The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity Labrousse, Guillaume; Vande Perre, Pierre; Parra, Genis; Jaffrelot, Marion; Leroy, Laura; Chibon, Frederic; Escudie, Frederic; Selves, Janick; Hoffmann, Jean-Sebastien; Guimbaud, Rosine; Lutzmann, Malik Share Save
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EMT Transcription Factor ZEB1 Represses the Mutagenic POLθ-Mediated End-Joining Pathway in Breast Cancers Prodhomme, Melanie K.; Pommier, Roxane M.; Franchet, Camille; Fauvet, Frederique; Bergoglio, Valerie; Brousset, Pierre; Morel, Anne-Pierre; Brunac, Anne-Cecile; Devouassoux-Shisheboran, Mojgan; Petrilli, Virginie; Moyret-Lalle, Caroline; Hoffmann, Jean-Sebastien; Puisieux, Alain; Tissier, Agnes Share Save
eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss i n pancreatic cancer Muller, David; Shin, Sauyeun; de Rugy, Theo Goullet; Samain, Remi; Baer, Romain; Strehaiano, Manon; Masvidal-Sanz, Laia; Guillermet-Guibert, Julie; Jean, Christine; Tsukumo, Yoshinori; Sonenberg, Nahum; Marion, Frederic; Guilbaud, Nicolas; Hoffmann, Jean-Sebastien; Larsson, Ola; Bousquet, Corinne; Pyronnet, Stephane; Martineau, Yvan Share Save
MCM8- and MCM9 Deficiencies Cause Lifelong Increased Hematopoietic DNA Damage Driving p53-Dependent Myeloid Tumors Lutzmann, Malik; Bernex, Florence; de Jesus, Cindy da Costa; Hodroj, Dana; Marty, Caroline; Plo, Isabelle; Vainchenker, William; Tosolini, Marie; Forichon, Luc; Bret, Caroline; Queille, Sophie; Marchive, Candice; Hoffmann, Jean-Sebastien; Mechali, Marcel Share Save
Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing Gonzalez Besteiro, Marina A.; Calzetta, Nicolas L.; Loureiro, Sofia M.; Habif, Martin; Betous, Remy; Pillaire, Marie-Jeanne; Maffia, Antonio; Sabbioneda, Simone; Hoffmann, Jean-Sebastien; Gottifredi, Vanesa Share Save
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner Bianco, Julien N.; Bergoglio, Valerie; Lin, Yea-Lih; Pillaire, Marie-Jeanne; Schmitz, Anne-Lyne; Gilhodes, Julia; Lusque, Amelie; Mazieres, Julien; Lacroix-Triki, Magali; Roumeliotis, Theodoros, I; Choudhary, Jyoti; Moreaux, Jerome; Hoffmann, Jean-Sebastien; Tourriere, Helene; Pasero, Philippe Share Save
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DNA polymerase v gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status Grgurevic, Srdana; Montilla-Perez, Patricia; Bradbury, Alice; Gilhodes, Julia; Queille, Sophie; Pelofy, Sandrine; Bancaud, Aurelien; Filleron, Thomas; Ysebaert, Loic; Recher, Christian; Laurent, Guy; Fournie, Jean-Jacques; Cazaux, Christophe; Quillet-Mary, Anne; Hoffmann, Jean-Sebastien Share Save
MUS81 nuclease activity is essential for replication stress tolerance and chromosome segregation in BRCA2-deficient cells (vol 8, 15983, 2017) Lai, Xianning; Broderick, Ronan; Bergoglio, Valerie; Zimmer, Jutta; Badie, Sophie; Niedzwiedz, Wojciech; Hoffmann, Jean-Sebastien; Tarsounas, Madalena Share Save
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Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres Garcia-Exposito, Laura; Bournique, Elodie; Bergoglio, Valerie; Bose, Arindam; Barroso-Gonzalez, Jonathan; Zhang, Sufang; Roncaioli, Justin L.; Lee, Marietta; Wallace, Callen T.; Watkins, Simon C.; Opresko, Patricia L.; Hoffmann, Jean-Sebastien; O'Sullivan, Roderick J. Share Save
Cyclin Kinase-independent role of p21cDKN1A in the promotion of nascent DNA elongation in unstressed cells Mansilla, Sabrina F.; Bertolin, Agustina P.; Bergoglio, Valerie; Pillaire, Marie-Jeanne; Besteiro, Marina A. Gonzalez; Luzzani, Carlos; Miriuka, Santiago G.; Cazaux, Christophe; Hoffmann, Jean-Sebastien; Gottifredi, Vanesa Share Save
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