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Amy F.T. Arnsten

Yale University

84H-index
262Paper Count
3.2WCitation Count
Published Papers 111
Publication Date
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Region-specific proteomic analysis of aging rhesus macaques following chronic glutamate-carboxypeptidase-II (GCPII) inhibition elucidates potential treatment strategies for sporadic Alzheimer’s disease
errActa Neuropathologica Communications
IF5.7
err2026-10-03
err0
errOAAI
errAlexandra D. Steigmeyer; Alexandria S. Battison; Iris R. Liebman; Christopher H. van Dyck; Barbara S. Slusher; Amy F. T. Arnsten; Stacy A. Malaker; Dibyadeep Datta
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errSave
322. Dysregulation of Cav3.1 and Cav1.2 in vulnerable DLPFC pyramidal neurons: a mechanistic link to cognitive disorders
errInternational Journal of Neuropsychopharmacology
IF3.7
err2026-09-09
err0
errOAAI
errD Datta; S Yang; G Gonzalez-Burgos; J Enwright; D Arion; D Lewis; M Wang; A Arnsten
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errSave
Distinctive molecular mechanisms in higher cortical circuits confer vulnerability to mental disorders
errBiological Psychiatry
IF9
err2026-06-19
err0
errOAAI
errMin Wang; Veronica C. Galvin; Mary Kate P. Joyce; Dibyadeep Datta; Shengtao Yang; Anita A. Disney; Amy F.T. Arnsten
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errSave
Intrinsic neuronal diversity as a substrate for cortical area specialization in primate vision
errNature Communications
IF15.7
err2026-06-09
err0
errOAAI
errM. Feyerabend; S. Pommer; S. Mestern; M. S. Jimenez-Sosa; J. Rachel; J. Sunstrum; F. Preuss; V. A. Khatibi; R. Hinkel; M. Mietsch; S. Vijayraghavan; S. Everling; S. Treue; A. F. T. Arnsten; D. A. Lewis; S. J. Tripathy; G. Gonzalez-Burgos; W. Inoue; A. Neef; J. F. Staiger; J. Martinez-Trujillo
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Kynurenic acid signaling expands in human and nonhuman primates and impairs dorsolateral prefrontal cortical cognition that is key to mental illness
errMolecular Psychiatry
IF10.1
err2025-12-18
err0
PREAI
errShengtao Yang; Dibyadeep Datta; Fenna M. Krienen; Elizabeth Woo; Athena May; George M. Anderson; Veronica C. Galvin; Guillermo Gonzalez-Burgos; David A. Lewis; Emi Ling; Steven A. McCarroll; Amy FT Arnsten; Min Wang
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errSave
Ryanodine receptor 2-mediated calcium leak is associated with increased glyoxalase I in the aging brain
errJCI INSIGHT
IF6.1
err2025-11-24
err0
errOAAI
errWoo, Elizabeth; Datta, Dibyadeep; Bathla, Shveta; Beatty, Hannah; Caglayan, Pinar; Albizu, Ashley Kristant; Lam, Tukiet T.; Kanyo, Jean; Joyce, Mary Kate; Leslie, Shannon; Uchendu, Stacy; Delong, Jonathan; Guan, Qinyue Stacy; Li, Jiaxin; Abramson, Efrat; Herman, Alison L.; Cooper, Dawson; Licznerski, Pawel; Horvath, Tamas L.; Jonas, Elizabeth A.; Nairn, Angus C.; Arnsten, Amy F. T.; Sansing, Lauren H.
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errSave
A novel multimodal pharmacologic approach using guanfacine, N-acetylcysteine, and donepezil in severe TBI: a case series
errFRONTIERS IN REHABILITATION SCIENCES
IF1.9
err2025-10-24
err0
errOAAI
errFesharaki-Zadeh, Arman; Belliveau, Timothy; Pietrzak, Robert H.; Arnsten, Amy
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errSave
Prefrontal cortical NR2B-containing NMDA receptors are essential for spatial working memory performance
errTranslational Psychiatry
IF6.2
err2025-10-06
err0
errOAAI
errJiyun Peng; Gongwu Wang; Yingying Han; Lili Qu; Min Wang; Amy F. T. Arnsten; Jingxia Cai; Baoming Li
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errSave
An integrated view of the relationships between amyloid, tau, and inflammatory pathophysiology in Alzheimer's disease
errAlzheimer's & Dementia
IF11.1
err2025-08-06
err0
errOAAI
errAmy F. T. Arnsten; Kelly Del Tredici; Nicolas R. Barthélemy; Mariano Gabitto; Christopher H. van Dyck; Edward Lein; Heiko Braak; Dibyadeep Datta
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errSave
The neuropathologic basis for translational biomarker development in the macaque model of late-onset Alzheimer's disease
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2025-03-01
err0
PREAI
errZeiss, Caroline J.; Huttner, Anita; Nairn, Angus C.; Arnsten, Amy; Datta, Dibyadeep; Strittmatter, Stephen M.; Wyk, Brent Vander; Duque, Alvaro
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errSave
SUSCEPTIBLE PYRAMIDAL NEURONS IN PRIMATE DORSOLATERAL PREFRONTAL CORTEX EXPRESS AN ENRICHED CALCIUM INTERACTOME: CRITICAL ROLE OF CALBINDIN AND CAV1.2 IN HIGHER-ORDER COGNITION
errINTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
IF3.7
err2025-02-12
err0
errOAAI
errDatta, Dibyadeep; Yang, Shengtao; Joyce, Mary Kate; Woo, Elizabeth; Mccarroll, Steven; Gonzalez-Burgos, Guillermo; Perone, Isabella; Uchendu, Stacy; Ling, Emi; Goldman, Raye; Berretta, Sabrina; Murray, John; Morozov, Yury; Arellano, Jon; Duque, Alvaro; Rakic, Pasko; O'dell, Ryan; van Dyck, Christopher H.; Lewis, David A.; Wang, Min; Krienen, Fenna; Arnsten, Amy
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Stress and Inflammation Target Dorsolateral Prefrontal Cortex Function: Neural Mechanisms Underlying Weakened Cognitive Control
errBIOLOGICAL PSYCHIATRY
IF9
err2025-02-01
err7
PREAI
errJoyce, Mary Kate P.; Uchendu, Stacy; Arnsten, Amy F. T.
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errSave
The etiology and prevention of early-stage tau pathology in higher cortical circuits: Insights from aging rhesus macaques
errALZHEIMERS & DEMENTIA
IF11.1
err2025-01-08
err0
errOAAI
errDatta, D; Arnsten, AFT
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errSave
β1-adrenoceptor expression on GABAergic interneurons in primate dorsolateral prefrontal cortex: potential role in stress-induced cognitive dysfunction
errNEUROBIOLOGY OF STRESS
IF3.6
err2024-05-01
err6
errOAAI
errJoyce, M. K. P.; Yang, S.; Morin, K.; Duque, A.; Arellano, J.; Datta, D.; Wang, M.; Arnsten, A. F. T.
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errSave
Nanoscale imaging of pT217-tau in aged rhesusmacaque entorhinal and dorsolateral prefrontal cortex: Evidence of interneuronal trafficking and early-stage neurodegeneration
errALZHEIMERS & DEMENTIA
IF11.1
err2024-03-06
err2
errOAAI
errDatta, Dibyadeep; Perone, Isabella; Wijegunawardana, Denethi; Liang, Feng; Morozov, Yury M.; Arellano, Jon; Duque, Alvaro; Xie, Zhongcong; van Dyck, Christopher H.; Joyce, Mary Kate P.; Arnsten, Amy F. T.
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Nanoscale imaging of pT217-tau in aged rhesus macaque: Trans-synaptic propagation and seeding of tau pathology in entorhinal cortex
errJOURNAL OF THE NEUROLOGICAL SCIENCES
IF3.2
err2023-12-01
err0
PREAI
errDatta, Dibyadeep; Arnsten, Amy
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The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J
errEuropean Journal of Nuclear Medicine and Molecular Imaging
IF7.6
err2023-11-13
err4
PREAI
errToyonaga, Takuya; Khattar, Nikkita; Wu, Yanjun; Lu, Yihuan; Naganawa, Mika; Gallezot, Jean-Dominique; Matuskey, David; Mecca, Adam P.; Pittman, Brian; Dias, Mark; Nabulsi, Nabeel B.; Finnema, Sjoerd J.; Chen, Ming-Kai; Arnsten, Amy; Radhakrishnan, Rajiv; Skosnik, Patrick D.; D'Souza, Deepak Cyril; Esterlis, Irina; Huang, Yiyun; van Dyck, Christopher H.; Carson, Richard E.
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Chronic GCPII (glutamate-carboxypeptidase-II) inhibition reduces pT217Tau levels in the entorhinal and dorsolateral prefrontal cortices of aged macaques
errALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS
IF6.8
err2023-10-31
err4
errOAAI
errBathla, Shveta; Datta, Dibyadeep; Liang, Feng; Barthelemy, Nicolas; Wiseman, Robyn; Slusher, Barbara S.; Asher, Jennifer; Zeiss, Caroline; Ekanayake-Alper, Dil; Holden, Daniel; Terwilliger, Gordon; Duque, Alvaro; Arellano, Jon; van Dyck, Christopher; Bateman, Randall J.; Xie, Zhongcong; Nairn, Angus C.; Arnsten, Amy F. T.
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Scientific Rationale for the Treatment of Cognitive Deficits from Long COVID
errNEUROLOGY INTERNATIONAL
IF3
err2023-05-31
err14
errOAAI
errZadeh, Arman Fesharaki; Arnsten, Amy F. T.; Wang, Min
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errSave
Scientific rationale for the use of α2A-adrenoceptor agonists in treating neuroinflammatory cognitive disorders
errMOLECULAR PSYCHIATRY
IF10.1
err2023-04-07
err5
errOAAI
errArnsten, Amy F. T.; Ishizawa, Yumiko; Xie, Zhongcong
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errSave

Research Directions

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Co-authors
Cooperation Journals
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Trevor W. Robbins
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Eric J. Nestler
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Edward T. Bullmore
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D
Dennis S. Charney
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M
Michael O’Donovan
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