Not logged inThe miR-124-AMPAR pathway connects polygenic risks with behavioral changes shared between schizophrenia and bipolar disorder
Namkung, Ho; Yukitake, Hiroshi; Fukudome, Daisuke; Lee, Brian J.; Tian, Mengnan; Ursini, Gianluca; Saito, Atsushi; Lam, Shravika; Kannan, Suvarnambiga; Srivastava, Rupali; Niwa, Minae; Sharma, Kamal; Zandi, Peter; Jaaro-Peled, Hanna; Ishizuka, Koko; Chatterjee, Nilanjan; Huganir, Richard L.; Sawa, Akira .png)
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SaveSex-specific involvement of the Notch-JAG pathway in social recognitionJaaro-Peled, Hanna; Landek-Salgado, Melissa A.; Cascella, Nicola G.; Nucifora, Frederick C. Jr Jr; Coughlin, Jennifer M.; Nestadt, Gerald; Sedlak, Thomas W.; Lavoie, Joelle; De Silva, Sarah; Lee, Somin; Tajinda, Katsunori; Hiyama, Hideki; Ishizuka, Koko; Yang, Kun; Sawa, Akira Share Save Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuitJaaro-Peled, Hanna; Kumar, Sunil; Hughes, Dalton; Sumitomo, Akiko; Kim, Sun-Hong; Zoubovsky, Sandra; Hirota-Tsuyada, Yuki; Zala, Diana; Bruyere, Julie; Katz, Brittany M.; Huang, Beverly; Flores, Rafael; Narayan, Soumya; Hou, Zhipeng; Economides, Aris N.; Hikida, Takatoshi; Wetsel, William C.; Deisseroth, Karl; Mori, Susumu; Brandon, Nicholas J.; Tanaka, Motomasa; Ishizuka, Koko; Houslay, Miles D.; Saudou, Frederic; Dzirasa, Kafui; Sawa, Akira; Tomoda, Toshifumi Share Save Share Save [11C](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired miceOoms, Maarten; Tsujikawa, Tetsuya; Lohith, Talakad G.; Mabins, Sanche N.; Zoghbi, Sami S.; Sumitomo, Akiko; Jaaro-Peled, Hanna; Kimura, Yasuyuki; Telu, Sanjay; Pike, Victor W.; Tomoda, Toshifumi; Innis, Robert B.; Sawa, Akira; Fujita, Masahiro Share Save Share Save DISC1 a key molecular lead in psychiatry and neurodevelopment: No-More Disrupted-in-Schizophrenia 1Niwa, M.; Cash-Padgett, T.; Kubo, K-I; Saito, A.; Ishii, K.; Sumitomo, A.; Taniguchi, Y.; Ishizuka, K.; Jaaro-Peled, H.; Tomoda, T.; Nakajima, K.; Sawa, A.; Kamiya, A. Share Save Interneuronal DISC1 regulates NRG1-ErbB4 signalling and excitatory-inhibitory synapse formation in the mature cortexSeshadri, Saurav; Faust, Travis; Ishizuka, Koko; Delevich, Kristen; Chung, Youjin; Kim, Sun-Hong; Cowles, Martis; Niwa, Minae; Jaaro-Peled, Hanna; Tomoda, Toshifumi; Lai, Cary; Anton, E. S.; Li, Bo; Sawa, Akira Share Save Adolescent cannabis exposure interacts with mutant DISC1 to produce impaired adult emotional memoryBallinger, Michael D.; Saito, Atsushi; Abazyan, Bagrat; Taniguchi, Yu; Huang, Ching-Hsun; Ito, Koki; Zhu, Xiaolei; Segal, Hadar; Jaaro-Peled, Hanna; Sawa, Akira; Mackie, Ken; Pletnikov, Mikhail V.; Kamiya, Atsushi Share Save Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pickl knockout miceNomura, J.; Jaaro-Peled, H.; Lewis, E.; Nunez-Abades, P.; Huppe-Gourgues, F.; Cash-Padgett, T.; Emiliani, F.; Kondo, M. A.; Furuya, A.; Landek-Salgado, M. A.; Ayhan, Y.; Kamiya, A.; Takumi, T.; Huganir, R.; Pletnikov, M.; O'Donnell, P.; Sawa, A. Share Save DISC1 regulates trafficking and processing of APP and Aβ generationShahani, N.; Seshadri, S.; Jaaro-Peled, H.; Ishizuka, K.; Hirota-Tsuyada, Y.; Wang, Q.; Koga, M.; Sedlak, T. W.; Korth, C.; Brandon, N. J.; Kamiya, A.; Subramaniam, S.; Tomoda, T.; Sawa, A. Share Save Share Save Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate controlKondo, M. A.; Tajinda, K.; Colantuoni, C.; Hiyama, H.; Seshadri, S.; Huang, B.; Pou, S.; Furukori, K.; Hookway, C.; Jaaro-Peled, H.; Kano, S-I; Matsuoka, N.; Harada, K.; Ni, K.; Pevsner, J.; Sawa, A. Share Save Subcortical dopaminergic deficits in a DISC1 mutant model: a study in direct reference to human molecular brain imagingJaaro-Peled, Hanna; Niwa, Minae; Foss, Catherine A.; Murai, Rina; de los Reyes, Samantha; Kamiya, Atsushi; Mateo, Yolanda; O'Donnell, Patricio; Cascella, Nicola G.; Nabeshima, Toshitaka; Guilarte, Tomas R.; Pomper, Martin G.; Sawa, Akira Share Save Share Save Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral DeficitsNiwa, Minae; Kamiya, Atsushi; Murai, Rina; Kubo, Ken-ichiro; Gruber, Aaron J.; Tomita, Keni; Lu, Lingling; Tomisato, Shuta; Jaaro-Peled, Hanna; Seshadri, Saurav; Hiyama, Hideki; Huang, Beverly; Kohda, Kazuhisa; Noda, Yukihiro; O'Donnell, Patricio; Nakajima, Kazunori; Sawa, Akira; Nabeshima, Toshitaka Share Save Share Save Share Save Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humansHikida, Takatoshi; Jaaro-Peled, Hanna; Seshadri, Saurav; Oishi, Kenichi; Hookway, Caroline; Kong, Stephanie; Wu, Di; Xue, Rong; Andrade, Manuella; Tankou, Stephanie; Mori, Susumu; Gallagher, Michela; Ishizuka, Koko; Pletnikov, Mikhail; Kida, Satoshi; Sawa, Akira Share Save 
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