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Frederick A. Schmitt

University of Kentucky

81H-index
425Paper Count
2.5WCitation Count
Published Papers 149
Publication Date
The association between APOE 𝜀4 carrierships and the detection of amyloid positivity using an Alzheimer's disease proteomic blood test in asymptomatic Down syndrome
err2026-04-11
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errOAAI
errLubnaa Badriyyah Abdullah; Fan Zhang; Melissa Petersen; James Hall; Benjamin L. Handen; Mark Mapstone; Brad Christian; Elizabeth Head; Sigan Harley; Howard Andrews; Joseph H Lee; Dana Tudorascu; Christy Hom; Shahid Zaman; Adam M Brickman; Diana Rosas; Annie Cohen; Jordan P Harp; Frederick Schmitt; Lauren Ptomey; Jeffrey M. Burns; Ira T Lott; Florence Lai; Charles Laymon; Carlos Cruchaga; Sid O'Bryant; Beau M. Ances
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Imaging and plasma biomarkers for pathological accumulation in Down syndrome
errBrain
IF11.7
err2025-11-05
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PREAI
errJulie K Wisch; Ziqiao Jiao; James T Kennedy; Ann D Cohen; Zinayida Schlachetzki; Melissa Petersen; Benjamin L Handen; Bradley T Christian; Mark Mapstone; H Diana Rosas; Florence Lai; Joseph H Lee; Sharon J Krinsky-McHale; Frederick A Schmitt; Jordan P Harp; Christy Hom; Ira T Lott; Sigan Hartley; Shahid Zaman; Lauren Ptomey; Jeffrey M Burns; Dana Tudorascu; Laura Ibanez; Michael S Rafii; Elizabeth Head; Beau M Ances
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Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer's disease in down syndrome
err2025-09-21
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errOAAI
errCherie A. Stringer; Haley K.S. Miyasato; Kevin A. Camey; Krina A. Ghadia; Elizabeth J. Andrews; Phong T. Ngo; Jesse R. Pascual; Sierra T. Wright; Justine A. Silva; Brianna M. Gawronski; Lourdes Gonzalez; Kevin A. Wood; Michael J. Phelan; Florence Lai; Frederick A. Schmitt; Jordan P. Harp; Adam M. Brickman; Patrick J. Lao; Mark E. Mapstone; Julia K. Kofler; Milos D. Ikonomovic; Elizabeth Head
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Age and sex are associated with Alzheimer's disease neuropathology in Down syndrome
err2025-07-17
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errElizabeth J. Andrews; Phong T. Ngo; Jesse R. Pascual; Freddy Gonzalez; Michael Phelan; Sierra T. Wright; Jordan Harp; Frederick Schmitt; Florence Lai
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Estimation of events in cohort studies based on probability of cognitive impairment
err2025-06-26
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PREAI
errJiyeon Park; Erin L Abner; Pei Wang; Changrui Liu; Gregory Jicha; Jordan P Harp; Frederick A Schmitt; Richard J Kryscio
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Longitudinal investigation of gait and Alzheimer's disease in adults with Down syndrome
err2025-04-28
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errBarry, A; Peven, JC; Handen, BL; Bolt, D; Krinsky-McHale, SJ; Hom, CL; Clare, ICH; Glueck, A; Harp, J; Schmitt, F; Zammit, M; Minhas, D; Luo, WQ; Laymon, C; Price, J; Lee, JH; Lott, I; Cohen, A; Ances, BM; Pulsifer, M; Rosa, HD; Lai, F; Zaman, SH; Head, E; Mapstone, M; Christian, BT; Hartley, SL
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Two-year feasibility and safety of open-label autologous peripheral nerve tissue implantation during deep brain stimulation in patients with Parkinson's disease
err2025-02-25
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errQuintero, Jorge E.; Chau, Monica J.; Slevin, John T.; Koehl, Lisa; Gurwell, Julie A.; Wallace, Elizabeth; Kryscio, Richard J.; El Khouli, Riham; Anderson-Mooney, Amelia J.; Schmitt, Frederick A.; Gerhardt, Greg A.; van Horne, Craig G.
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Breast cancer lighthouse non-interventional hybrid real-world study: Molecular characterization and 2-year effectiveness data
err2024-09-01
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PREAI
errNogal Dias, A. M.; Matos, A. L. V.; Gosalbez Pequeno, B. E.; Braga, S.; Pinto, L. I.; Pego, A.; Abreu, C. D.; Ferreira, M. I. R.; Gago, P. F.; Faustino, I.; Matos Pina, I. M.; Marques, C. P.; Passos-Coelho, J. L. C.; Branco, F. P.; Simoes, J. C. D. L.; Luis, I. V. Vaz; Schmitt, F.; Costa, L.; Domingues, M.; Bras, D.
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Associations between IL-1(3, (3 , IL-6, and TNFα α polymorphisms and longitudinal trajectories of cognitive function in non-demented older adults
err2024-08-01
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errLawrence, Karen A.; Gloger, Elana M.; Pinheiro, Cristina N.; Schmitt, Frederick A.; Segerstrom, Suzanne C.
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A blunted TH17 cytokine signature in women with mild cognitive impairment: insights from inflammatory profiling of a community-based cohort of older adults
err2023-10-07
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errOAAI
errBachstetter, Adam D.; Lutshumba, Jenny; Winford, Edric; Abner, Erin L.; Martin, Barbra J.; Harp, Jordan P.; Van Eldik, Linda J.; Schmitt, Frederick A.; Wilcock, Donna M.; Stowe, Ann M.; Jicha, Gregory A.; Nikolajczyk, Barbara S.
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A neuropathologic feature of brain aging: multi-lumen vascular profiles
err2023-08-28
err1
errOAAI
errIghodaro, Eseosa T.; Shahidehpour, Ryan K.; Bachstetter, Adam D.; Abner, Erin L.; Nelson, Ruth S.; Fardo, David W.; Shih, Andy Y.; Grant, Roger I.; Neltner, Janna H.; Schmitt, Frederick A.; Jicha, Gregory A.; Kryscio, Richard J.; Wilcock, Donna M.; Van Eldik, Linda J.; Nelson, Peter T.
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Plasma NT1-tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts
err2023-07-12
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errStern, Andrew M.; Van Pelt, Kathryn L.; Liu, Lei; Anderson, Amirah K.; Ostaszewski, Beth; Mapstone, Mark; O'Bryant, Sid; Petersen, Melissa E.; Christian, Bradley T.; Handen, Benjamin L.; Selkoe, Dennis J.; Schmitt, Frederick; Head, Elizabeth
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Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort
err2023-06-02
err18
errOAAI
errNelson, Ruth S.; Abner, Erin L.; Jicha, Gregory A.; Schmitt, Frederick A.; Di, Jing; Wilcock, Donna M.; Barber, Justin M.; Van Eldik, Linda J.; Katsumata, Yuriko; Fardo, David W.; Nelson, Peter T.
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Primitive Reflexes and Dementia in Adults With Down Syndrome
err2022-02-01
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errHarp, Jordan; Koehl, Lisa; Van Pelt, Kathryn; Head, Elizabeth; Jicha, Gregory; Robertson, William; Lightner, Donita; Lott, Ira; Schmitt, Frederick
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Cancer diagnosis is associated with a lower burden of dementia and less Alzheimer's-type neuropathology
errBRAIN
IF11.7
err2022-01-30
err18
errOAAI
errKaranth, Shama D.; Katsumata, Yuriko; Nelson, Peter T.; Fardo, David W.; McDowell, Jaclyn K.; Schmitt, Frederick A.; Kryscio, Richard J.; Browning, Steven R.; Braithwaite, Dejana; Arnold, Susanne M.; Abner, Erin L.
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Selective Impairment of Long-Range Default Mode Network Functional Connectivity as a Biomarker for Preclinical Alzheimer's Disease in People with Down Syndrome
err2022-01-04
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errOAAI
errDiProspero, Natalie D.; Keator, David B.; Phelan, Michael; van Erp, Theo G. M.; Doran, Eric; Powell, David K.; Van Pelt, Kathryn L.; Schmitt, Frederick A.; Head, Elizabeth; Lott, Ira T.; Yassa, Michael A.
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Identifying dementia in Down syndrome with the Severe Impairment Battery, Brief Praxis Test and Dementia Scale for People with Learning Disabilities
err2021-11-16
err4
errOAAI
errWallace, E. R.; Harp, J. P.; Van Pelt, K. L.; Koehl, L. M.; Caban-Holt, A. M.; Anderson-Mooney, A. J.; Jicha, G. A.; Lightner, D. D.; Robertson, W. C.; Head, E.; Schmitt, F. A.
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Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome
err2021-08-25
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errOAAI
errHarp, Jordan P.; Koehl, Lisa M.; Van Pelt, Kathryn L.; Hom, Christy L.; Doran, Eric; Head, Elizabeth; Lott, Ira T.; Schmitt, Frederick A.
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Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies
err2021-07-21
err14
errOAAI
errKaranth, Shama D.; Schmitt, Frederick A.; Nelson, Peter T.; Katsumata, Yuriko; Kryscio, Richard J.; Fardo, David W.; Harp, Jordan P.; Abner, Erin L.
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