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J

James R. Sellers

National Heart, Lung, and Blood Institute

81H-index
359Paper Count
2.2WCitation Count
Published Papers 104
Publication Date
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Structural basis of nonmuscle myosin-2 autoinhibition mechanisms
errNature Communications
IF15.7
err2026-06-20
err0
errOAAI
errSarah M. Heissler; Giovanna Grandinetti; James R. Sellers; Krishna Chinthalapudi
errShare
errSave
Src-dependent tyrosine-phosphorylation of NM2A has a protective role against bacterial pore-forming toxins
errPLoS Pathogens
IF4.9
err2026-02-23
err0
PREAI
errBrito, Claudia; Mesquita, Francisco S.; Pereira, Joana M.; Osorio, Daniel S.; Billington, Neil; Lima, Ricardo R.; Vale-Costa, Silvia; Sellers, James R.; Cabanes, Didier; Carvalho, Ana X.; Sousa, Sandra
errShare
errSave
Effect of Load on Non-Muscle Myosin 2 Paralog Filaments in a Biomimetic Contractile Actin Array
errSMALL
IF12.1
err2025-11-01
err0
errOAAI
errBleicher, Philip; Han, David; Billington, Neil; Hart, Ryan; Combs, Christian A.; Qazi, Shureed; Chandrasekar, Indra; Knutson, Jay R.; Sellers, James R.
errShare
errSave
Development of clinically viable non-muscle myosin II small molecule inhibitors
errCell
IF42.5
err2025-07-01
err0
PREAI
errLaszlo Radnai; Erica J. Young; Carlos Kikuti; Katalin Toth; Minghai Zhou; Madalyn Hafenbreidel; Rebecca F. Stremel; Li Lin; Paolo Pasetto; Xiaomin Jin; Aagam Patel; Michael Conlon; Sherri B. Briggs; Leïla Heidsieck; H. Lee Sweeney; James Sellers; Teresa Krieger-Burke; William H. Martin; Jay Sisco; Steven Young; Paul Pearson; Gavin Rumbaugh; Gian Luca Araldi; Steven K. Duddy; Michael D. Cameron; Matthew Surman; Anne Houdusse; Patrick R. Griffin; Theodore M. Kamenecka; Courtney A. Miller
errShare
errSave
Myosin-5 varies its step length to carry cargo straight along the irregular F-actin track
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-20
err2
errOAAI
errFineberga, Adam; Takagi, Yasuharu; Thirumurugan, Kavitha; Andrecka, Joanna; Billingtonc, Neil; Young, Gavin; Cole, Daniel; Burgess, Stan A.; Curd, Alistair P.; Hammer, John A.; Sellers, James R.; Kukura, Philipp; Knight, Peter J.
errShare
errSave
Molecular regulatory mechanism of human myosin-7a
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-10-01
err3
errOAAI
errHollo, Alexandra; Billington, Neil; Takagi, Yasuharu; Kengyel, Andras; Sellers, James R.; Liu, Rong
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errSave
A brain specific alternatively spliced isoform of nonmuscle myosin IIA lacks its mechanoenzymatic activities
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-09-01
err2
errOAAI
errDas, Samprita; Mallick, Ditipriya; Sarkar, Sourav; Billington, Neil; Sellers, James R.; Jana, Siddhartha S.
errShare
errSave
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism
errJOURNAL OF CELL BIOLOGY
IF6.4
err2023-02-14
err4
errOAAI
errCannon, Kevin S.; Vargas-Muniz, Jose M.; Billington, Neil; Seim, Ian; Ekena, Joanne; Sellers, James R.; Gladfelter, Amy. S.
errShare
errSave
Flagella-like beating of actin bundles driven by self-organized myosin waves
errNATURE PHYSICS
IF18.4
err2022-08-08
err8
errOAAI
errPochitaloff, Marie; Miranda, Martin; Richard, Mathieu; Chaiyasitdhi, Atitheb; Takagi, Yasuharu; Cao, Wenxiang; De la Cruz, Enrique M.; Sellers, James R.; Joanny, Jean-Francois; Juelicher, Frank; Blanchoin, Laurent; Martin, Pascal
errShare
errSave
Pericentrin interacts with Kinesin-1 to drive centriole motility
errJOURNAL OF CELL BIOLOGY
IF6.4
err2022-08-05
err3
errOAAI
errHannaford, Matthew R.; Liu, Rong; Billington, Neil; Swider, Zachary T.; Galletta, Brian J.; Fagerstrom, Carey J.; Combs, Christian; Sellers, James R.; Rusan, Nasser M.
errShare
errSave
Cryo-EM structure of the autoinhibited state of myosin-2
errSCIENCE ADVANCES
IF12.5
err2021-12-24
err25
errOAAI
errHeissler, Sarah M.; Arora, Amandeep S.; Billington, Neil; Sellers, James R.; Chinthalapudi, Krishna
errShare
errSave
Discovery of Selective Inhibitors for In Vitro and In Vivo Interrogation of Skeletal Myosin II
errACS CHEMICAL BIOLOGY
IF3.8
err2021-09-24
err4
PREAI
errRadnai, Laszlo; Surman, Matthew; Hafenbreidel, Madalyn; Young, Erica J.; Stremel, Rebecca F.; Lin, Li; Bdiri, Bilel; Pasetto, Paolo; Jin, Xiaomin; Geedy, Mackenzie; Partridge, Joni-Rae; Patel, Aagam; Conlon, Michael; Sellers, James R.; Cameron, Michael D.; Rumbaugh, Gavin; Griffin, Patrick R.; Kamenecka, Theodore M.; Miller, Courtney A.
errShare
errSave
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily
errJOURNAL OF CELL SCIENCE
IF3.6
err2021-04-27
err43
errOAAI
errNishimura, Yukako; Shi, Shidong; Zhang, Fang; Liu, Rong; Takagi, Yasuharu; Bershadsky, Alexander D.; Viasnoff, Virgile; Sellers, James R.
errShare
errSave
A binding protein regulates myosin-7a dimerization and actin bundle assembly
errNATURE COMMUNICATIONS
IF15.7
err2021-01-25
err17
errOAAI
errLiu, Rong; Billington, Neil; Yang, Yi; Bond, Charles; Hong, Amy; Siththanandan, Verl; Takagi, Yasuharu; Sellers, James R.
errShare
errSave
The ATPase mechanism of myosin 15, the molecular motor mutated in DFNB3 human deafness
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-01-01
err12
errOAAI
errJiang, Fangfang; Takagi, Yasuharu; Shams, Arik; Heissler, Sarah M.; Friedman, Thomas B.; Sellers, James R.; Bird, Jonathan E.
errShare
errSave
Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells
errCURRENT BIOLOGY
IF7.5
err2020-07-01
err24
errOAAI
errAguilar-Cuenca, Rocio; Llorente-Gonzalez, Clara; Chapman, Jessica R.; Talayero, Vanessa C.; Garrido-Casado, Marina; Delgado-Arevalo, Cristina; Millan-Salanova, Maria; Shabanowitz, Jeffrey; Hunt, Donald F.; Sellers, James R.; Heissler, Sarah M.; Vicente-Manzanares, Miguel
errShare
errSave
Competition between kinesin-1 and myosin-V defines Drosophila posterior determination
errELIFE
IF0
err2020-02-14
err42
errOAAI
errLu, Wen; Lakonishok, Margot; Liu, Rong; Billington, Neil; Rich, Ashley; Glotzer, Michael; Sellers, James R.; Gelfand, Vladimir, I
errShare
errSave
Perfringolysin O-Induced Plasma Membrane Pores Trigger Actomyosin Remodeling and Endoplasmic Reticulum Redistribution
errTOXINS
IF4
err2019-07-17
err9
errOAAI
errBrito, Claudia; Mesquita, Francisco S.; Bleck, Christopher K. E.; Sellers, James R.; Cabanes, Didier; Sousa, Sandra
errShare
errSave
Remarkable Rigidity of the Single α-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-05-22
err34
errOAAI
errBarnes, C. Ashley; Shen, Yang; Ying, Jinfa; Takagi, Yasuharu; Torchia, Dennis A.; Sellers, James R.; Bax, Ad
errShare
errSave
Nonmuscle myosin-2 isoforms
errCURRENT BIOLOGY
IF7.5
err2019-04-01
err28
errOAAI
errSellers, James R.; Heissler, Sarah M.
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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Ad Bax
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Martin A. Schwartz
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李
李林 (Lin Li)
H-index: 115 · Papers: 3.0K
J
Jeffrey Shabanowitz
H-index: 112 · Papers: 392
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