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Combination of the Novel RAF Dimer Inhibitor Brimarafenib With the MEK Inhibitor Mirdametinib Is Effective Against NRAS Mutant Melanoma Tellenbach, Flavia L.; Seiler, Luzia; Johnson, Mark; Rehrauer, Hubert; Schukla, Prachi; Martinez-Gomez, Julia; Stoffel, Corinne I.; Kamal, Adeela; Dummer, Reinhard; Levesque, Mitchell P.; Eichhoff, Ossia M. Share Save
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Measurement report: In-flight and ground-based measurements of nitrogen oxide emissions from latest-generation jet engines and 100 % sustainable aviation fuel Harlass, Theresa; Dischl, Rebecca; Kaufmann, Stefan; Maerkl, Raphael; Sauer, Daniel; Scheibe, Monika; Stock, Paul; Braeuer, Tiziana; Doernbrack, Andreas; Roiger, Anke; Schlager, Hans; Schumann, Ulrich; Puehl, Magdalena; Schripp, Tobias; Grein, Tobias; Bondorf, Linda; Renard, Charles; Gauthier, Maxime; Johnson, Mark; Luff, Darren; Madden, Paul; Swann, Peter; Ahrens, Denise; Sallinen, Reetu; Voigt, Christiane Share Save
TEAD inhibition by SW-682 potentiates activity of targeted therapies in NSCLC models Chen, L.; Jove, V.; de Marval, P. Miliani; DuBose, R.; Saha, S.; Johnson, M.; Ahn, S.; Powell, K.; Liu, F.; Lawhorn, B.; Gwaltney, S.; Shao, W.; Lin, T. A. Share Save
Rational combination of pan-TEAD inhibitor SW-682 and MEK inhibitor mirdametinib in head and neck squamous cell carcinomas leads to synergistic response Schirmer, A.; Chen, L.; Celentano, L.; Chanelo, A.; Jove, V.; DuBose, R.; Saha, S.; Johnson, M.; Lawhorn, B.; Gwaltney, S.; Lin, T. A.; de Marval, P. Miliani Share Save
Xeniaphyllane and Xeniolide Diterpenes from the Deep-Sea Soft Coral Paragorgia arborea Afoullouss, Sam; Young, Ryan M.; Jennings, Laurence K.; Doyle, Jason; Croke, Karen; Livorsi, Debora; Adams, John H.; Johnson, Mark P.; Thomas, Olivier P.; Allcock, A. Louise Share Save
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Characterizing and Predicting nvPM Size Distributions for Aviation Emission Inventories and Environmental Impact Durdina, Lukas; Durand, Eliot; Edebeli, Jacinta; Spirig, Curdin; Brem, Benjamin T.; Elser, Miriam; Siegerist, Frithjof; Johnson, Mark; Sevcenco, Yura A.; Crayford, Andrew P. Share Save
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A first-in-human, phase 1a/1b, open-label, dose-escalation and expansion study to investigate the safety, pharmacokinetics, and antitumor activity of the RAF dimer inhibitor BGB-3245 in patients with advanced or refractory tumors Schram, Alison M.; Subbiah, Vivek; Sullivan, Ryan; Cosman, Rasha; Liu, Jia; Sbar, Eric I.; Thuy Hoang; Chen, Jiarong; Johnson, Mark; Amoruccio, Vincent; Shearer, Todd; Kamal, Adeela; Lewis, Jocelyn; Shao, Wenlin; Edris, Badreddin; Luo, Lusong; Desai, Jayesh Share Save
SW-682: A novel TEAD inhibitor for the treatment of cancers bearing mutations in the Hippo signaling pathway Chen, Lei; de Marval, Paula Milani; Powell, Kendall; Johnson, Mark; Falls, Greg; Lawhorn, Brian; Candi, Aurelie; Kilonda, Amuri; Vanderhoydonck, Bart; Marchand, Arnaud; Versele, Matthias; Halder, Georg; Gwaltney, Stephen L.; Kamal, Adeela Share Save
Correction for particle loss in a regulatory aviation nvPM emissions system using measured particle size Durand, Eliot; Durdina, Lukas; Smallwood, Greg; Johnson, Mark; Spirig, Curdin; Edebeli, Jacinta; Roth, Manuel; Brem, Benjamin; Sevcenco, Yura; Crayford, Andrew Share Save
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Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme Avalon, Nicole E.; Nafie, Jordan; Verissimo, Carolina De Marco; Warrensford, Luke C.; Dietrick, Sarah G.; Pittman, Amanda R.; Young, Ryan M.; Kearns, Fiona L.; Smalley, Tracess; Binning, Jennifer M.; Dalton, John P.; Johnson, Mark P.; Woodcock, H. Lee; Allcock, A. Louise; Baker, Bill J. Share Save