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Atrial Fibrillation Related Titin Truncation Is Associated With Atrial Myopathy in Patient-Derived Induced Pluripotent Stem Cell Disease Models Huang, Kate; Ashraf, Mishal; Rohani, Leili; Luo, Yinhan; Sacayanan, Ardin; Huang, Haojun; Haegert, Anne; Volik, Stanislav; Sar, Funda; Lebihan, Stephane; Liew, Janet; Backx, Peter H.; Roberts, Jason D.; Tibbits, Glen F.; Churko, Jared M.; Sanatani, Shubhayan; Collins, Colin; Brunham, Liam R.; Laksman, Zachary Share Save
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Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways Hamidzada, Homaira; Pascual-Gil, Simon; Wu, Qinghua; Kent, Gregory M.; Masse, Stephane; Kantores, Crystal; Kuzmanov, Uros; Gomez-Garcia, M. Juliana; Rafatian, Naimeh; Gorman, Renee A.; Wauchop, Marianne; Chen, Wenliang; Landau, Shira; Subha, Tasnia; Atkins, Michael H.; Zhao, Yimu; Beroncal, Erika; Fernandes, Ian; Nanthakumar, Jared; Vohra, Shabana; Wang, Erika Y.; Sadikov, Tamilla Valdman; Razani, Babak; McGaha, Tracy L.; Andreazza, Ana C.; Gramolini, Anthony; Backx, Peter H.; Nanthakumar, Kumaraswamy; Laflamme, Michael A.; Keller, Gordon; Radisic, Milica; Epelman, Slava Share Save
TAK1 Activation by NLRP3 Deficiency Confers Cardioprotection Against Pressure Overload-Induced Cardiomyocyte Pyroptosis and Hypertrophy Li, Xuan; You, Jieyun; Dai, Fangjie; Wang, Shijun; Yang, Feng Hua; Wang, Xingxu; Ding, Zhiwen; Huang, Jiayuan; Chen, Liming; Abudureyimu, Miyesaier; Tang, Haiyang; Yang, Xiangdong; Xiang, Yaozu; Backx, Peter H.; Ren, Jun; Ge, Junbo; Zou, Yunzeng; Wu, Jian Share Save
Maturation of iPSC-derived cardiomyocytes in a heart-on-a-chip device enables modeling of dilated cardiomyopathy caused by R222Q-SCN5A mutation Wauchop, Marianne; Rafatian, Naimeh; Zhao, Yimu; Chen, Wenliang; Gagliardi, Mark; Masse, Stephane; Cox, Brian J.; Lai, Patrick; Liang, Timothy; Landau, Shira; Protze, Stephanie; Gao, Xiao Dong; Wang, Erika Yan; Tung, Kelvin Chan; Laksman, Zachary; Lu, Rick Xing Ze; Keller, Gordon; Nanthakumar, Kumaraswamy; Radisic, Milica; Backx, Peter H. Share Save
Phosphorylation Signatures Of Human Heart Failure: Characterizing Dilated Cardiomyopathy-associated Signaling Pathways At The Cardiomyocyte Intercalated Disc Reitz, Cristine J.; Tavassoli, Marjan; Kim, Da Hye; Shah, Saumya; Lakin, Robert; Teng, Allen; Zhou, Yu-Qing; Li, Wenping; Hadipour-Lakmehsari, Sina; Backx, Peter; Emili, Andrew; Oudit, Gavin Y.; Kuzmanov, Uros; Gramolini, Anthony Share Save
Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3 Reitz, Cristine J.; Tavassoli, Marjan; Kim, Da Hye; Shah, Saumya; Lakin, Robert; Teng, Allen C. T.; Zhou, Yu-Qing; Li, Wenping; Hadipour-Lakmehsari, Sina; Backx, Peter H.; Emili, Andrew; Oudit, Gavin Y.; Kuzmanov, Uros; Gramolini, Anthony O. Share Save
Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy Joza, N; Oudit, GY; Brown, D; Bénit, P; Kassiri, Z; Vahsen, N; Benoit, L; Patel, MM; Nowikovsky, K; Vassault, A; Backx, PH; Wada, T; Kroerner, G; Rustin, P; Penninger, JA Share Save
Increased BRAF Heterodimerization Is the Common Pathogenic Mechanism for Noonan Syndrome-Associated RAF1 Mutants Wu, Xue; Yin, Jiani; Simpson, Jeremy; Kim, Kyoung-Han; Gu, Shengqing; Hong, Jenny H.; Bayliss, Peter; Backx, Peter H.; Neel, Benjamin G.; Araki, Toshiyuki Share Save
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts Teng, Allen; Gu, Liyang; Di Paola, Michelle; Lakin, Robert; Williams, Zachary; Au, Aaron; ChenLeo, Wenliang; Callaghan, Neal; Hakem-Zadeh, Farigol; Zhou, Yu-Qing; Fatah, Meena; Chatterjee, Diptendu; Jourdan, L. Jane; Liu, Jack; Simmons, Craig; Kislinger, Thomas; Yip, Christopher; Backx, Peter; Gourdie, Robert; Hamilton, Robert; Gramolini, Anthony Share Save
Tmem65 is critical for the structure and function of the intercalated discs in mouse hearts Teng, Allen C. T.; Gu, Liyang; Di Paola, Michelle; Lakin, Robert; Williams, Zachary J.; Au, Aaron; Chen, Wenliang; Callaghan, Neal, I; Zadeh, Farigol Hakem; Zhou, Yu-Qing; Fatah, Meena; Chatterjee, Diptendu; Jourdan, L. Jane; Liu, Jack; Simmons, Craig A.; Kislinger, Thomas; Yip, Christopher M.; Backx, Peter H.; Gourdie, Robert G.; Hamilton, Robert M.; Gramolini, Anthony O. Share Save
Tmem65 Is Critical For The Structure And Function Of The Intercalated Discs In Mouse Hearts Teng, Allen; Gu, Liyang; Di Paola, Michelle; Lakin, Robert; Williams, Zachary; Au, Aaron; Chen, Wenliang; Callaghan, Neal I.; Zadeh, Farigol Hakem; Zhou, Yu-Qing; Fatah, Meena; Chatterjee, Diptendu; Jourdan, Jane; Jack, Liu; Simmons, Craig A.; Kislinger, Thomas; Yip, Christopher; Backx, Peter; Gourdie, Robert G.; Hamilton, Robert M.; Gramolini, Anthony Share Save
Differential mRNA Expression and Circular RNA-Based Competitive Endogenous RNA Networks in the Three Stages of Heart Failure in Transverse Aortic Constriction Mice Li, Xiang; Tan, Weijiang; Zheng, Shuang; Pyle, W. Glen; Zhu, Caiyi; Chen, Honghua; Kang, Le; Wu, Jian; Zou, Yunzeng; Backx, Peter H.; Yang, Feng Hua Share Save
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Transcriptomic Bioinformatic Analyses of Atria Uncover Involvement of Pathways Related to Strain and Post-translational Modification of Collagen in Increased Atrial Fibrillation Vulnerability in Intensely Exercised Mice Oh, Yena; Yang, Sibao; Liu, Xueyan; Jana, Sayantan; Izaddoustdar, Farzad; Gao, Xiaodong; Debi, Ryan; Kim, Dae-Kyum; Kim, Kyoung-Han; Yang, Ping; Kassiri, Zamaneh; Lakin, Robert; Backx, Peter H. Share Save
Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation Kim, Young M.; Lakin, Robert; Zhang, Hao; Liu, Jack; Sachedina, Ayaaz; Singh, Maneesh; Wilson, Emily; Perez, Marco; Verma, Subodh; Quertermous, Thomas; Olgin, Jeffrey; Backx, Peter H.; Ashley, Euan A. Share Save
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