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Paula M. Canas

cibb

38H-index
84Paper Count
4.5KCitation Count
Published Papers 39
Publication Date
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Genetic deletion of adenosine A2A receptors attenuates memory deterioration and alterations of synaptic plasticity and metabolic controllers in the hippocampus and prefrontal cortex of aged mice
errGeroScience
IF5.4
err2026-03-30
err0
errOAAI
errCátia R. Lopes; Daniela Madeira; Madalena Piteira; Pedro Valada; Joana Santos; Henrique B. Silva; Francisco Q. Gonçalves; Ângelo R. Tomé; Paula M. Canas; João Pedro Lopes; Samira G. Ferreira; Paula Agostinho; Rodrigo A. Cunha
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Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer's Disease
errJOURNAL OF ALZHEIMERS DISEASE
IF3.1
err2025-02-06
err16
PREAI
errAmorim, Joao A.; Canas, Paula M.; Tome, Angelo R.; Rolo, Anabela P.; Agostinho, Paula; Palmeira, Carlos M.; Cunha, Rodrigo A.
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Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2023-10-29
err3
errOAAI
errMadeira, Daniela; Domingues, Joana; Lopes, Catia R.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula
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Adenosine A2A receptors control generalization of contextual fear in rats
errTRANSLATIONAL PSYCHIATRY
IF6.2
err2023-10-12
err3
errOAAI
errSimoes, Ana P.; Portes, Marina A. M.; Lopes, Catia R.; Vanz, Felipe; Lourenco, Vanessa S.; Pliassova, Anna; Gaspar, Ingride L.; Silva, Henrique B.; Tome, Angelo R.; Canas, Paula M.; Prediger, Rui D.; Cunha, Rodrigo A.
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Astrocytic A2A receptors silencing negatively impacts hippocampal synaptic plasticity and memory of adult mice
errGLIA
IF5.1
err2023-05-15
err4
PREAI
errMadeira, Daniela; Lopes, Catia R.; Simoes, Ana P.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula
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Redox signalling and proteostasis in neurodegeneration: In vivo effects of the mitochondria-targeted antioxidant MitoQ in Huntington's disease mice
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2023-03-01
err0
PREAI
errPinho, Brigida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M. A.
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Adenosine A2A receptors blockade attenuates dexamethasone-induced alterations in cultured astrocytes
errPURINERGIC SIGNALLING
IF2.4
err2022-04-27
err6
errOAAI
errMadeira, Daniela; Dias, Liliana; Santos, Patricia; Cunha, Rodrigo A.; Agostinho, Paula; Canas, Paula M.
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Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunction
errNEUROBIOLOGY OF DISEASE
IF5.6
err2021-09-01
err21
errOAAI
errAugusto, Elisabete; Goncalves, Francisco Q.; Real, Joana E.; Silva, Henrique B.; Pochmann, Daniela; Silva, Tiago S.; Matos, Marco; Goncalves, Nelio; Tome, Angelo R.; Chen, Jiang-Fan; Canas, Paula M.; Cunha, Rodrigo A.
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Adenosine A2A Receptors as Biomarkers of Brain Diseases
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2021-07-16
err21
errOAAI
errMoreira-de-Sa, Ana; Lourenco, Vanessa S.; Canas, Paula M.; Cunha, Rodrigo A.
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Deletion of CD73 increases exercise power in mice
errPURINERGIC SIGNALLING
IF2.4
err2021-07-03
err5
errOAAI
errAguiar, Aderbal S., Jr.; Speck, Ana Elisa; Canas, Paula M.; Cunha, Rodrigo A.
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L-α-aminoadipate causes astrocyte pathology with negative impact on mouse hippocampal synaptic plasticity and memory
errFASEB JOURNAL
IF4.2
err2021-07-01
err13
PREAI
errPereira, Marlene F.; Amaral, Ines M.; Lopes, Catia; Leitao, Catarina; Madeira, Daniela; Lopes, Joao P.; Goncalves, Francisco Q.; Canas, Paula M.; Cunha, Rodrigo A.; Agostinho, Paula
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Use of knockout mice to explore CNS effects of adenosine
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2021-05-01
err8
PREAI
errLopes, Catia R.; Lourenco, Vanessa S.; Tome, Angelo R.; Cunha, Rodrigo A.; Canas, Paula M.
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Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndrome
errNEUROBIOLOGY OF DISEASE
IF5.6
err2020-12-01
err14
errOAAI
errMoreira-de-Sa, Ana; Goncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Tome, Angelo R.; Cunha, Rodrigo A.; Canas, Paula M.
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errSave
Purinergic signaling orchestrating neuron-glia communication
errPHARMACOLOGICAL RESEARCH
IF10.5
err2020-12-01
err63
PREAI
errAgostinho, Paula; Madeira, Daniela; Dias, Liliana; Simoes, Ana Patricia; Cunha, Rodrigo A.; Canas, Paula M.
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errSave
Neuronal adenosine A2A receptors signal ergogenic effects of caffeine
errSCIENTIFIC REPORTS
IF3.9
err2020-08-07
err50
errOAAI
errAguiar, Aderbal S., Jr.; Speck, Ana Elisa; Canas, Paula M.; Cunha, Rodrigo A.
errShare
errSave
The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2020-01-01
err46
errOAAI
errPinho, Brigida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M. A.
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errSave
Synaptic and memory dysfunction in a β-amyloid model of early Alzheimer's disease depends on increased formation of ATP-derived extracellular adenosine
errNEUROBIOLOGY OF DISEASE
IF5.6
err2019-12-01
err91
errOAAI
errGoncalves, Francisco Q.; Lopes, Joao P.; Silva, Henrique B.; Lemos, Cristina; Silva, Antonio C.; Goncalves, Nell; Tome, Angelo R.; Ferreira, Samira G.; Canas, Paula M.; Rial, Daniel; Agostinho, Paula; Cunha, Rodrigo A.
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Enhanced ATP release and CD73-mediated adenosine formation sustain adenosine A2A receptor over-activation in a rat model of Parkinson's disease
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2019-08-01
err45
errOAAI
errCarmo, Marta; Goncalves, Francisco Q.; Anas, Paula M. C.; Oses, Jean-Pierre; Fernandes, Francisco D.; Duarte, Filipe, V; Palmeira, Carlos M.; Tome, Angelo R.; Agostinho, Paula; Andrade, Geanne M.; Cunha, Rodrigo A.
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Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in Rats
errFRONTIERS IN NEUROSCIENCE
IF3.2
err2018-09-21
err47
errOAAI
errMoreira-Silva, Daniel; Carrettiero, Daniel C.; Oliveira, Adriele S. A.; Rodrigues, Samanta; dos Santos-Lopes, Joyce; Canas, Paula M.; Cunha, Rodrigo A.; Almeida, Maria C.; Ferreira, Tatiana L.
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Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease
errNEUROBIOLOGY OF DISEASE
IF5.6
err2018-09-01
err71
PREAI
errSilva, Antonio C.; Lemos, Cristina; Goncalves, Francisco Q.; Pliassova, Anna V.; Machado, Nuno J.; Silva, Henrique B.; Canas, Paula M.; Cunha, Rodrigo A.; Lopes, Joao Pedro; Agostinho, Paula
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Research Directions

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Co-authors
Cooperation Journals
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Michael P. Murphy
H-index: 142 · Papers: 777
M
Michael Bäder
H-index: 117 · Papers: 1.4K
F
Félix Carvalho
H-index: 104 · Papers: 780
C
Catarina R. Oliveira
H-index: 97 · Papers: 512
E
Edward S. Boyden
H-index: 95 · Papers: 622
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