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Nicolas Servant

Institut Curie

49H-index
265Paper Count
1.7WCitation Count
Published Papers 108
Publication Date
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AI-driven multi-omics integration in cancer research and precision oncology
errnpj Precision Oncology
IF8
err2026-08-07
err0
errOAAI
errDorian Bochaton; Nicolas Servant; Hakim Benkirane; Sarah Watson; Julien Vibert
errShare
errSave
Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid leukaemia
errNature Communications
IF15.7
err2026-07-28
err0
errOAAI
errAlessandro Donada; Gurvan Hermange; Tiziana Tocci; Adil Midoun; Giulio Prevedello; Louisa Hadj Abed; Délia Dupré; Wenjie Sun; Idan Milo; Sabrina Tenreira Bento; Constandina Pospori; Andrew J. Innes; Christophe Willekens; Jacques Vargaftig; David Michonneau; Cristina Lo Celso; Nicolas Servant; Ken R. Duffy; Hervé Isambert; Paul-Henry Cournède; Lucie Laplane; Leïla Perié
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errSave
Integrative genomic and transcriptomic profiles from a prospective cervical cancer study
errnpj Precision Oncology
IF8
err2026-07-22
err0
errOAAI
errSolenn Barraud; Lolita Lecompte; Rebecca Loison; Stacy Cyrille; Emmanuelle Jeannot; Elodie Girard; Sylvain Baulande; Patricia Legoix; Abderaouf Hamza; Fabrice Lecuru; Léa Pauly; Constance Lamy; Célia Dupain; Olfa Chouchane-Mlik; Alexandra Oniga; Michel Mittelbronn; Christophe Le Tourneau; Aurélien Latouche; Nicolas Servant; Ivan Bièche; Suzy M. Scholl; Maud Kamal
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errSave
Constitutional BRCA1 Methylation is associated with high level of tumoral BRCA1 methylation and homologous recombination deficiency in triple-negative breast cancer
errnpj Breast Cancer
IF7.6
err2026-02-07
err0
errOAAI
errJustine Pasanisi; Constance Lamy; Lolita Lecompte; Sophie Vacher; Mathias Schwartz; Abderaouf Hamza; Sandrine M. Caputo; Sabrina Ibadioune; Laura Courtois; Frédérique Berger; Vincent Cockenpot; Sylvain Baulande; Jean-Yves Pierga; Celine Callens; Samia Melaabi; Chrystelle Colas; Eric Pasmant; Maud Kamal; Célia Dupain; Nicolas Servant; Christophe Le Tourneau; Ivan Bièche
errShare
errSave
Ether lipids influence cancer cell fate by modulating iron uptake
errNature Communications
IF15.7
err2026-01-27
err0
errOAAI
errRyan P. Mansell; Sebastian Müller; Jia-Shu Yang; Sarah Innes-Gold; Sunny Das; Ferenc Reinhardt; Kim Janina Sigmund; Vaishnavi V. Phadnis; Zhengpeng Wan; Jillian Stark; Daehee Hwang; Fabien Sindikubwabo; Laurène Syx; Nicolas Servant; Elinor Ng Eaton; Julio L. Sampaio; George W. Bell; Prathapan Thiru; Amartya Viravalli; Amy Deik; Clary B. Clish; Paula T. Hammond; Roger D. Kamm; Adam E. Cohen; Ilya Levental; Natalie Boehnke; Victor W. Hsu; Kandice R. Levental; Raphaël Rodriguez; Robert A. Weinberg; Whitney S. Henry
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Escape from X inactivation is directly modulated by Xist noncoding RNA
errNature Cell Biology
IF19.1
err2025-12-15
err0
errOAAI
errAntonia Hauth; Jasper Panten; Emma Kneuss; Christel Picard; Nicolas Servant; Isabell Rall; Yuvia A. Pérez-Rico; Lena Clerquin; Nila Servaas; Laura Villacorta; Ferris Jung; Christy Luong; Howard Y. Chang; Judith B. Zaugg; Oliver Stegle; Duncan T. Odom; Edith Heard; Agnese Loda
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errSave
A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription
errNature Communications
IF15.7
err2025-12-10
err0
errOAAI
errAnna Minello; Jesus Gomez-Escudero; Sreerama Chaitanya Sridhara; Charlotte Martin; Elodie Girard; Juan C. Cañas; Yasin Memari; Maria Rose Bustos; Antonio Galarreta; Virginie Boucherit; Evgeny Imyanitov; Sigridur Klara Bodvarsdottir; Sylvain Baulande; Anne Vincent-Salomon; Nicolas Servant; Matthias Altmeyer; Stefan Sigurdsson; Dominique Stoppa-Lyonnet; Serena Nik-Zainal; Aura Carreira
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errSave
Management and survival of patients with cancer of unknown primary discussed by a French national multidisciplinary tumour board: a retrospective analysis
errThe Lancet Regional Health - Europe
IF0
err2025-11-07
err0
errOAAI
errCélia Dupain; Nicolas Jacquin; Aurélien Latouche; Zoé Nevière; Pierre Gestraud; Abderaouf Hamza; Kenza Nedara; Vincent Cockenpot; Janick Selves; Yves Allory; Laëtitia Chanas; Maud Milder; Isabelle Soubeyran; Hélène Blons; Anna Patrikidou; Axel de Bernardi; Julien Masliah-Planchon; Odette Mariani; Etienne Rouleau; Fabienne Escande; Sandrine Boyault; Pierre Saintigny; Florence de Fraipont; Pierre Blanc; Jennifer Wong; Camille Tlemsani; Isabelle Guillou; Julie Flavius; Noemie Fuentealba; Maud Kamal; Ivan Bièche; Nicolas Servant; Christophe Le Tourneau; Sarah Watson
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errSave
Identification of microprotein-coding intronic polyadenylation isoforms and function in genotoxic anticancer drug response
errGenome Biology
IF9.4
err2025-10-24
err0
errOAAI
errAlexandre Devaux; Iris Tanaka; Quentin Fouilleul; Amélie Heneman-Masurel; Mandy Cadix; Sophie Michallet; Alina Chakraborty; Céline M. Labbé; Nicolas Fontrodona; Subhadarsini Sahoo; Jean-Baptiste Claude; Marc Deloger; Pierre Gestraud; Ludovic Tessier; Hussein Mortada; Sonia Lameiras; Virginie Raynal; Sylvain Baulande; Nicolas Servant; Didier Auboeuf; Béatrice Eymin; Stéphan Vagner; Martin Dutertre
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errSave
Steady-state neuron-predominant LINE-1 encoded ORF1p protein and LINE-1 RNA increase with aging in the mouse and human brain
errELIFE
IF0
err2025-09-25
err0
PREAI
errBonnifet, Tom; Sinnassamy, Sandra; Massiani-Beaudoin, Olivia; Mailly, Philippe; Monnet, Heloise; Loew, Damarys; Lombard, Berangere; Servant, Nicolas; Joshi, Rajiv L.; Fuchs, Julia
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errSave
Molecular analysis of lung adenocarcinomas from the SAFIR02-Lung cohort reveals new metastasis-associated copy-number alterations including frequent mutant-specific KRAS-allelic imbalance and identifies CDKN2A homozygous deletions as an independent biomarker of poor prognosis
errBritish Journal of Cancer
IF6.8
err2025-09-11
err0
PREAI
errAbderaouf Hamza; Pierre Gestraud; Maryam Karimi; Alicia Tran-Dien; Laurène Syx; Sophie Vacher; Quentin Peretti; Ludovic Lacroix; Valery Attignon; Isabelle Soubeyran; Pascal Jézéquel; David Planchard; Samia Melaabi; Trenton Dailey-Chwalibóg; Marta Jimenez; Stefan Michiels; Nicolas Servant; Christophe Le Tourneau; Nicolas Girard; Fabrice André; Benjamin Besse; Maud Kamal; Fabrice Barlesi; Ivan Bièche
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errSave
Internal validation strategy for high dimensional prognosis model: A simulation study and application to transcriptomic in head and neck tumors
errComputational and Structural Biotechnology Journal
IF4.1
err2025-09-03
err0
errOAAI
errAntoine DUBRAY-VAUTRIN; Victor GRAVRAND; Grégoire MARRET; Constance LAMY; Jerzy KLIJANIENKO; Sophie VACHER; Ladidi AHMANACHE; Maud KAMAL; Olivier CHOUSSY; Nicolas SERVANT; Célia DUPAIN; Christophe LE TOURNEAU; Jimmy MULLAERT
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errSave
Efficacy of pembrolizumab and vorinostat combination in patients with recurrent and/or metastatic squamous cell carcinomas: a phase 2 basket trial
errNature Cancer
IF28.5
err2025-06-30
err0
errOAAI
errEdith Borcoman; Bastien Cabarrou; Miguel Francisco; Frédéric Bigot; François Ghiringhelli; Damien Vansteene; François Legrand; Maral Halladjian; Célia Dupain; Olivia Le Saux; Clelia Coutzac; Christian Borel; Raphael Chaltiel; Benoit You; Carlos Gomez-Roca; Sophie Cousin; Elodie Coquan; Aurélien Lambert; Esma Saada-Bouzid; Xavier Durando; Mathilde Saint-Ghislain; Gianmaria Frige; Elena Guerini-Rocco; Maria Manuela Tonini; Ivan Bièche; Zahra Castel-Ajgal; Grégoire Marret; Marie-Paule Sablin; Emmanuelle Jeannot; Fabrice Andre; Thomas Filleron; Marta Jimenez; Luca Mazzarella; Nicolas Servant; Maud Kamal; Christophe Le Tourneau
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errSave
Activation of lysosomal iron triggers ferroptosis in cancer
errNATURE
IF48.5
err2025-05-07
err0
errOAAI
errCaneque, Tatiana; Baron, Leeroy; Mueller, Sebastian; Carmona, Alanis; Colombeau, Ludovic; Versini, Antoine; Solier, Stephanie; Gaillet, Christine; Sindikubwabo, Fabien; Sampaio, Julio L.; Sabatier, Marie; Mishima, Eikan; Picard-Bernes, Armel; Syx, Laurene; Servant, Nicolas; Lombard, Berangere; Loew, Damarys; Zheng, Jiashuo; Proneth, Bettina; Thoidingjam, Leishemba K.; Grimaud, Laurence; Fraser, Cameron S.; Szylo, Krystina J.; Kazarian, Emma Der; Bonnet, Caroline; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe; Santofimia-Castano, Patricia; Estaras, Matias; Dusetti, Nelson; Iovanna, Juan Lucio; Cunha, Antonio Sa; Pittau, Gabriella; Hammel, Pascal; Tzanis, Dimitri; Bonvalot, Sylvie; Watson, Sarah; Upadhyay, Aditya; Pratt, Derek A.; Freitas, Florencio Porto; Angeli, Jose Pedro Friedmann; Stockwell, Brent R.; Conrad, Marcus; Ubellacker, Jessalyn M.
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Deciphering molecular relapse and intra-tumor heterogeneity in non-metastatic resectable head and neck squamous cell carcinoma using circulating tumor DNA
errORAL ONCOLOGY
IF3.9
err2025-01-01
err0
PREAI
errMarret, Gregoire; Lamy, Constance; Vacher, Sophie; Cabel, Luc; Sene, Mathieu; Ahmanache, Ladidi; Courtois, Laura; El Beaino, Zakhia; Klijanienko, Jerzy; Martinat, Charlotte; Servant, Nicolas; Kamoun, Choumouss; Halladjian, Maral; Bronzini, Thierry; Balsat, Cedric; Laes, Jean-Francois; Prevot, Aubray; Sauvage, Sebastien; Lienard, Maxime; Martin, Emmanuel; Genin, Berengere; Badois, Nathalie; Lesnik, Maria; Dubray-Vautrin, Antoine; Choussy, Olivier; Ghanem, Wahib; Taouachi, Rabah; Planchon, Julien Masliah; Bieche, Ivan; Le Tourneau, Christophe; Kamal, Maud
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Methylation, Gene Expression, and Risk Genotypes at the TERT-CLPTM1L Locus in Cervical Cancer
errMOLECULAR CARCINOGENESIS
IF3.2
err2024-10-01
err1
PREAI
errRamachandran, Dhanya; Mao, Qianqian; Liao, Dandan; Kamal, Maud; Schuermann, Peter; Eisenblaetter, Rieke; Geffers, Robert; Balint, Balazs; Lecompte, Lolita; Servant, Nicolas; Cherif, Linda Larbi; Lamy, Constance; Baulande, Sylvain; Legoix, Patricia; Le Tourneau, Christophe; Latouche, Aurelien; Hillemanns, Peter; Scholl, Suzy; Doerk, Thilo
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Copy number alterations in metastatic and early breast tumours: prognostic and acquired biomarkers of resistance to CDK4/6 inhibitors
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-08-02
err0
errOAAI
errSablin, Marie-Paule; Gestraud, Pierre; Jonas, Sarah Flora; Lamy, Constance; Lacroix-Triki, Magali; Bachelot, Thomas; Filleron, Thomas; Lacroix, Ludovic; Tran-Dien, Alicia; Jezequel, Pascal; Mauduit, Marjorie; Barros Monteiro, Janice; Jimenez, Marta; Michiels, Stefan; Attignon, Valery; Soubeyran, Isabelle; Driouch, Keltouma; Servant, Nicolas; Le Tourneau, Christophe; Kamal, Maud; Andre, Fabrice; Bieche, Ivan
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Metastatic renal cell carcinoma with occult primary: a multicenter prospective cohort
errNPJ PRECISION ONCOLOGY
IF8
err2024-07-18
err0
errOAAI
errJacquin, Nicolas; Flippot, Ronan; Masliah-Planchon, Julien; Grisay, Guillaume; Brillet, Riwan; Dupain, Celia; Kamal, Maud; Guillou, Isabelle; Gruel, Nadege; Servant, Nicolas; Gestraud, Pierre; Wong, Jennifer; Cockenpot, Vincent; Goncalves, Andreia; Selves, Janick; Blons, Helene; Rouleau, Etienne; Delattre, Olivier; Gervais, Claire; Le Tourneau, Christophe; Bieche, Ivan; Allory, Yves; Albiges, Laurence; Watson, Sarah
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NANOPORE SEQUENCING AS A CUTTING-EDGE TECHNOLOGY FOR MEDULLOBLASTOMA CLASSIFICATION
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errFilser, Mathilde; Torrejon, Jacob; Merchadou, Kevin; Girard, Elodie; Bourneix, Christine; Lemaitre, Elisa; Brillet, Riwan; Wong, Jennifer; Gentien, David; Rapinat, Audrey; Servant, Nicolas; Vasiljevic, Alexandre; Bertozzi, Anne-Isabelle; Raimbault, Sandra; Tauziede-Espariat, Arnault; Lhermitte, Benoit; Faure-Conter, Cecile; Icher, Celine; Berger, Claire; Maurage, Claude-Alain; Bodet, Damien; Meyronet, David; Uro-Coste, Emmanuelle; De Carli, Emilie; Forest, Fabien; Palenzuela, Gilles; Chotard, Guillaume; Gauchotte, Guillaume; Sudour, Helene; Mansuy, Ludovic; Deparis, Mariana; Machet, Marie-Christine; Faisant, Maxime; Entz-Werle, Natacha; Varlet, Pascale; Leblond, Pierre; Michalak-Provost, Sophie; Houdemont, Stephanie Proust; Rigau, Valerie; Doz, Francois; Bourdeaut, Franck; Delattre, Olivier; Ayrault, Olivier; Masliah-Planchon, Julien
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VC-resist glioblastoma cell state: vessel co-option as a key driver of chemoradiation resistance
errNATURE COMMUNICATIONS
IF15.7
err2024-04-29
err3
errOAAI
errPichol-Thievend, Cathy; Anezo, Oceane; Pettiwala, Aafrin M.; Bourmeau, Guillaume; Montagne, Remi; Lyne, Anne-Marie; Guichet, Pierre-Olivier; Deshors, Pauline; Ballestin, Alberto; Blanchard, Benjamin; Reveilles, Juliette; Ravi, Vidhya M.; Joseph, Kevin; Heiland, Dieter H.; Julien, Boris; Leboucher, Sophie; Besse, Laetitia; Legoix, Patricia; Dingli, Florent; Liva, Stephane; Loew, Damarys; Giani, Elisa; Ribecco, Valentino; Furumaya, Charita; Marcos-Kovandzic, Laura; Masliantsev, Konstantin; Daubon, Thomas; Wang, Lin; Diaz, Aaron A.; Schnell, Oliver; Beck, Jugen; Servant, Nicolas; Karayan-Tapon, Lucie; Cavalli, Florence M. G.; Seano, Giorgio
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Research Directions

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Co-authors
Cooperation Journals
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