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M

Markus Zweckstetter

german center for neurodegenerative diseases

90H-index
429Paper Count
2.8WCitation Count
Published Papers 196
Publication Date
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IFI16 restricts SARS-CoV-2 replication by disrupting nucleocapsid-driven phase separation
errCommunications Biology
IF5.1
err2026-06-01
err0
errOAAI
errIlaria Cislaghi; Sarah Turati; Dalila Vicario; Gloria Griffante; Shikha Chandel; Irene Lo Cigno; Ranieri Bizzarri; Barbara Storti; Tina Ukmar Godec; Milan Zachrdla; Markus Zweckstetter; Lucia Signorini; Kevin Kamau Maina; Serena Delbue; Cinzia Borgogna; Marisa Gariglio
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errSave
Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
errCell Reports
IF6.9
err2026-05-21
err0
errOAAI
errMichel Fricke; Anna Mechel; Lennart Evers; Björn Twellsieck; Jessica M. Grein; Maria-Sol Cima-Omori; Mohammed Al-Azzani; Tiago F. Outeiro; Markus Zweckstetter; Erika L.F. Holzbaur; C. Alexander Boecker
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errSave
A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features
errMolecular Neurodegeneration
IF17.5
err2025-09-28
err0
errOAAI
errChristof Brücke; Mohammed Al-Azzani; Nagendran Ramalingam; Maria Ramón; Rita L. Sousa; Fiamma Buratti; Michael Zech; Kevin Sicking; Leslie Amaral; Ellen Gelpi; Aswathy Chandran; Aishwarya Agarwal; Susana R. Chaves; Claudio O. Fernández; Ulf Dettmer; Janin Lautenschläger; Markus Zweckstetter; Ruben Fernandez Busnadiego; Alexander Zimprich; Tiago Fleming Outeiro
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errSave
A Novel α-Synuclein K58N Missense Variant in a Patient with Parkinson's Disease
errMovement Disorders
IF7.6
err2025-09-04
err0
errOAAI
errMohammed Al-Azzani PhD; Sandrina Weber MD; Nagendran Ramalingam PhD; Maria Ramón MSc; Liana Shvachiy PhD; Gonçalo Mestre MSc; Michael Zech MD; Kevin Sicking PhD; Alain Ibáñez de Opakua PhD; Vidyashree Jayanthi BSc; Leslie Amaral PhD; Aishwarya Agarwal PhD; Aswathy Chandran PhD; Susana R. Chaves PhD; Juliane Winkelmann MD; Claudia Trenkwalder MD; Maike Schwager MSc; Silke Pauli PhD; Ulf Dettmer PhD; Claudio O. Fernández PhD; Janin Lautenschläger PhD; Markus Zweckstetter PhD; Ruben Fernandez Busnadiego PhD; Brit Mollenhauer MD; Tiago Fleming Outeiro PhD
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Current practices in the study of biomolecular condensates: a community comment
errNature Communications
IF15.7
err2025-08-19
err0
errOAAI
errSimon Alberti; Paolo Arosio; Robert B. Best; Steven Boeynaems; Danfeng Cai; Rosana Collepardo-Guevara; Gregory L. Dignon; Rumiana Dimova; Shana Elbaum-Garfinkle; Nicolas L. Fawzi; Monika Fuxreiter; Amy S. Gladfelter; Alf Honigmann; Ankur Jain; Jerelle A. Joseph; Tuomas P. J. Knowles; Keren Lasker; Edward A. Lemke; Kresten Lindorff-Larsen; Reinhard Lipowsky; Jeetain Mittal; Samrat Mukhopadhyay; Sua Myong; Rohit V. Pappu; Karsten Rippe; Tatyana A. Shelkovnikova; Anthony G. Vecchiarelli; Susanne Wegmann; Huaiying Zhang; Mingjie Zhang; Chloe Zubieta; Markus Zweckstetter; Dorothee Dormann; Tanja Mittag
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errSave
Deep learning empowered sensor fusion boosts infant movement classification
errCOMMUNICATIONS MEDICINE
IF6.3
err2025-01-14
err0
errOAAI
errKulvicius, Tomas; Zhang, Dajie; Poustka, Luise; Boelte, Sven; Jahn, Lennart; Fluegge, Sarah; Kraft, Marc; Zweckstetter, Markus; Nielsen-Saines, Karin; Woergoetter, Florentin; Marschik, Peter B.
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errSave
Impact of distinct FG nucleoporin repeats on Nup98 self-association
errNATURE COMMUNICATIONS
IF15.7
err2024-05-07
err1
errOAAI
errde Opakua, Alain Ibanez; Pantoja, Christian F.; Cima-Omori, Maria-Sol; Dienemann, Christian; Zweckstetter, Markus
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errSave
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions
errNATURE COMMUNICATIONS
IF15.7
err2024-03-02
err3
errOAAI
errAnton, Rosa; Trevino, Miguel A.; Pantoja-Uceda, David; Felix, Sara; Babu, Maria; Cabrita, Eurico J.; Zweckstetter, Markus; Tinnefeld, Philip; Vera, Andres M.; Oroz, Javier
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errSave
Regulation of tau by peptidyl-prolyl isomerases
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2024-02-01
err1
errOAAI
errZhuang, Shannon; Chakraborty, Pijush; Zweckstetter, Markus
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errSave
Multimodal interactions drive chromatin phase separation and compaction
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2023-12-04
err4
errOAAI
errUkmar-Godec, Tina; Cima-Omori, Maria- Sol; Yerkesh, Zhadyra; Eswara, Karthik; Yu, Taekyung; Ramesh, Reshma; Riviere, Gwladys; de Opakua, Alain Ibanez; Fischle, Wolfgang; Zweckstetter, Markus
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errSave
Multivalent Tau/PSD-95 interactions arrest in vitro condensates and clusters mimicking the postsynaptic density
errNATURE COMMUNICATIONS
IF15.7
err2023-10-27
err12
errOAAI
errShen, Zheng; Sun, Daxiao; Savastano, Adriana; Varga, Sara Joana; Cima-Omori, Maria-Sol; Becker, Stefan; Honigmann, Alf; Zweckstetter, Markus
errShare
errSave
Role of aberrant phase separation in pathological protein aggregation
errCURRENT OPINION IN STRUCTURAL BIOLOGY
IF7
err2023-10-01
err20
PREAI
errChakraborty, Pijush; Zweckstetter, Markus
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errSave
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II
errNATURE COMMUNICATIONS
IF15.7
err2023-09-25
err15
errOAAI
errFlores-Solis, David; Lushpinskaia, Irina P.; Polyansky, Anton A.; Changiarath, Arya; Boehning, Marc; Mirkovic, Milana; Walshe, James; Pietrek, Lisa M.; Cramer, Patrick; Stelzl, Lukas S.; Zagrovic, Bojan; Zweckstetter, Markus
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errSave
Acetylation discriminates disease-specific tau deposition
errNATURE COMMUNICATIONS
IF15.7
err2023-09-22
err10
errOAAI
errChakraborty, Pijush; Riviere, Gwladys; Hebestreit, Alina; de Opakua, Alain Ibanez; Vorberg, Ina M.; Andreas, Loren B.; Zweckstetter, Markus
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errSave
Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology
errNATURE COMMUNICATIONS
IF15.7
err2023-09-06
err8
errOAAI
errHuang, Yongqi; Wen, Jitao; Ramirez, Lisa-Marie; Guemuesdil, Eymen; Pokhrel, Pravin; Man, Viet H.; Ye, Haiqiong; Han, Yue; Liu, Yunfei; Li, Ping; Su, Zhengding; Wang, Junmei; Mao, Hanbin; Zweckstetter, Markus; Perrett, Sarah; Wu, Si; Gao, Meng
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errSave
Alpha-synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain
errBRAIN PATHOLOGY
IF6.2
err2023-07-24
err8
errOAAI
errZhang, Shuyu; Dauer, Karina; Strohaeker, Timo; Tatenhorst, Lars; Gomes, Lucas Caldi; Mayer, Simon; Jung, Byung Chul; Kim, Woojin S. S.; Lee, Seung-Jae; Becker, Stefan; Liesche-Starnecker, Friederike; Zweckstetter, Markus; Lingor, Paul
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errSave
Molecular-level interplay between intrinsically disordered clients and Hsp90
errCURRENT OPINION IN CHEMICAL BIOLOGY
IF6.1
err2023-06-01
err2
PREAI
errRamirez, Lisa Marie; Zweckstetter, Markus
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errSave
Phosphatidylserine-dependent structure of synaptogyrin remodels the synaptic vesicle membrane
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2023-05-22
err7
errOAAI
errYu, Taekyung; Flores-Solis, David; Eastep, Gunnar N.; Becker, Stefan; Zweckstetter, Markus
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errSave
Tenth International Symposium on the Hsp90 chaperone machine Switzerland, October 19-23, 2022
errCELL STRESS & CHAPERONES
IF3.2
err2023-05-01
err1
errOAAI
errEdkins, Adrienne L. L.; Zweckstetter, Markus; Sawarkar, Ritwick
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errSave
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage
errNATURE COMMUNICATIONS
IF15.7
err2023-04-06
err6
errOAAI
errRosado-Ramos, Rita; Pocas, Goncalo M.; Marques, Daniela; Foito, Alexandre; Sevillano, David M.; Lopes-da-Silva, Mafalda; Goncalves, Luis G.; Menezes, Regina; Ottens, Marcel; Stewart, Derek; de Opakua, Alain Ibanez; Zweckstetter, Markus; Seabra, Miguel C.; Mendes, Cesar S.; Outeiro, Tiago Fleming; Domingos, Pedro M.; Santos, Claudia N.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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A
Ad Bax
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Glenda M. Halliday
H-index: 138 · Papers: 1.0K
T
Thomas Gasser
H-index: 137 · Papers: 1.4K
G
G. Marius Clore
H-index: 125 · Papers: 725
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