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M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors Smith, Kyle S.; Fischer, Tom T.; Han, Katie; Kostecka, Anna; Lin, Hong; Senfter, Daniel; Soliman, Taha; Stepien, Natalia; Volz, Stefanie; Schwarz, Nathalie; Wedig, Tatjana; Madlener, Sibylle; Haberler, Christine; Dhanda, Sandeep K.; Upadhyaya, Santhosh A.; Blackburn, Patrick R.; Schmook, Maria T.; De Bont, Judith; Haapasalo, Hannu; Dargvainiene, Justina; Leypoldt, Frank; Pfister, Stefan M.; Hulleman, Esther; Orr, Brent A.; Gajjar, Amar; Robinson, Giles W.; Haapasalo, Joonas; Nordfors, Kristiina; Gojo, Johannes; Pajtler, Kristian W.; Maass, Kendra K.; Northcott, Paul A. Share Save
Toward reducing the risk of cerebellar mutism syndrome: consensus statement from the Posterior Fossa Society Toescu, Sebastian M.; Pizer, Barry; Gump, William; Aquilina, Kristian; Avula, Shivaram; Mallucci, Conor; Parks, Christopher; Carai, Andrea; Robinson, Giles; Aldave, Guillermo; Baird, Lissa; Niazi, Toba; Keating, Robert; Klimo Jr, Paul Share Save
Efficacy and tolerability of mirdametinib (PD-0325901) in children, adolescents, and young adults with recurrent/progressive low-grade glioma: update from the SJ901 (NCT04923126) phase 1/2 clinical trial Vinitsky, Anna; Bag, Asim K.; Chiang, Jason; Li, Quian; Lin, Tong; Hoehn, Mary Ellen; Edwards, Angela; Storment, Diana; Singh, Anjali; Larkin, Jennifer; Bakare, Deborah; Simpson, Raven; Bertrand, Kelsey C.; Bagchi, Aditi; Weber, Michael D.; Qaddoumi, Ibrahim; Moreira, Daniel; Robinson, Giles W. Share Save
DIVERGENT MEDULLOBLASTOMA CHROMATIN STATES DISCLOSE KDM2B AS A SELECTIVE DEPENDENCY Tao, Ran; Erkek-Ozhan, Serap; Xu, Beisi; Matsui, Yurika; Mittal, Priya; Smith, Kyle; Li, Yiran; Gao, Qingsong; Darrow, Emily; Xu, Ruijie; Djekidel, Nadhir; Bajpai, Richa; Kumar, Rahul; Reilly, Colleen; Soliman, Taha; Hadley, Jennifer; Batts, Melissa; Bhanu, Natarajan; Gudenas, Brian; Paul, Leena; Lin, Hong; Lowe, Kim; Kutscher, Lena; Garcia, Benjamin; Pruett-Miller, Shondra; Zhou, Xin; Orr, Brent; Robinson, Giles; Wu, Gang; Korbel, Jan; Peng, Jamy; Pfister, Stefan; Northcott, Paul Share Save
PHASE 2 STUDY OF ALISERTIB IN COMBINATION THERAPY FOR NEWLY DIAGNOSED ATYPICAL TERATOID/RHABDOID TUMOR (AT/RT)- RESULTS FROM SJATRT STRATA B AND C Bagchi, Aditi; Upadhyaya, Santhosh A.; Dhanda, Sandeep; Billups, Catherine; Baxter, Patricia; Bendel, Anne; Aguillera, Dolly; Kilburn, Lindsey; Crawford, John; Partap, Sonia; Hanzlik, Emily; Tran, Quynh; Breuer, Alex; Qi, Wenjie; Lu, Congyu; Singh, Anjali; Richardson, Miya; Soans, Eroica; Klimo, Paul; Zhou, Xin; Thomas, Arzu O.; Orr, Brent; Merchant, Thomas; Robinson, Giles W.; Gajjar, Amar Share Save
An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival Smith, Kyle S.; Dhanda, Sandeep K.; Billups, Catherine A.; Sioson, Edgar; Lu, Congyu; Peraza, Airen Zaldivar; Gangwani, Karishma; Li, Yimei; Li, Qian; Lin, Tong; Michalski, Jeff M.; Packer, Roger J.; Olson, James M.; Leary, Sarah E. S.; Fouladi, Maryam; Gajjar, Amar; Zhou, Xin; Onar-Thomas, Arzu; Northcott, Paul A.; Robinson, Giles W. Share Save
Enhancing Medulloblastoma Classification: Integrating IHC and DNA Methylation Data from the SJMB12 Clinical Trial Dhanda, Sandeep Kumar; Breuer, Alexander; Tran, Quynh T.; Smith, Kyle; Strother, Douglas; Fisher, Michael; Bendel, Anne; Hwang, Eugene; Zhao, Sibo; Gottardo, Nick; Hassall, Timothy; Elster, Jennifer; Perreault, Sebastien; Ramaswamy, Vijay; Partap, Sonia; Laughton, Stephen; Cohn, Richard; Chintagumpala, Murali; McCowage, Geoff; Sullivan, Michale; Sayour, Elias; Bowers, Daniel C.; Marks, Asher; Wright, Avery; Onar-Thomas, Arzu; Ellison, David; Northcott, Paul A.; Gajjar, Amar; Robinson, Giles W.; Orr, Brent A. Share Save
Molecular insights into response and resistance in children with relapsed/refractory brain tumors on ribociclib combination therapy: results from SJDAWN Han, Katie; Robinson, Giles W.; Smith, Kyle S.; Kostecka, Anna; Dhanda, Sandeep K.; Lin, Tong; Filipovic, David; Lin, Hong; Mikkelsen, Margit; Sabin, Noah D.; Onar-Thomas, Arzu; Roussel, Martine F.; Stewart, Clinton; Orr, Brent A.; Gajjar, Amar; Northcott, Paul A. Share Save
AN ONCOGENIC PHOTORECEPTOR PROGRAM UNIFIES DISTINCT CENTRAL NERVOUS SYSTEM TUMORS Gudenas, Brian; Ahmad, Shiekh; Englinger, Bernhard; Liu, Anthony; Zhao, Miao; Paul, Leena; Hadley, Jennifer; Lin, Hong; Li, Yiran; Batts, Melissa; Mittal, Priya; Wu, Stephanie; Lewis, Sara; Han, Katie; Soliman, Taha; Janke, Laure; Meredith, David; Pfaff, Elke; Gojo, Johannes; Cotter, Jennifer; Klimo, Paul; Boop, Frederick; Gajjar, Amar; Robinson, Giles; Rosen, Gabriela; Alexandrescu, Sanda; Jones, David; Orr, Brent; Swartling, Fredrik; Filbin, Mariella; Northcott, Paul Share Save
Robust classification of pediatric brain tumors from cell-free DNA methylomes Smith, Kyle; Fischer, Tom; Han, Katie; Kostecka, Anna; Lin, Hong; Senfter, Daniel; Stepien, Natalia; Volz, Stefanie; Schwarz, Nathalie; Wedig, Tatjana; Madlener, Sibylle; Haberler, Christine; Dhanda, Sandeep; Upadhyaya, Santhosh; Schmook, Maria; De Bont, Judith; Haapasalo, Hannu; Dargvainiene, Justina; Leypoldt, Frank; Pfister, Stefan; Hulleman, Esther; Gajjar, Amar; Robinson, Giles; Haapasalo, Joonas; Nordfors, Kristiina; Gojo, Johannes; Maass, Kendra; Pajtler, Kristian; Northcott, Paul Share Save
Locoregional B7-H3 CAR-T cells for relapsed/refractory CNS tumors: preliminary clinical experience of the Loc3CAR trial Bertrand, Kelsey; Hanzlik, Emily; Chiang, Jason; Pinto, Soniya; Selukar, Subodh; Kosteka, Anna; Smith, Kyle; Han, Katie; Ibanez, Jorge; Tlais, Dana; Orr, Brent; Langfitt, Deanna; Metais, Jean-Yves; Lockey, Timothy; Willis, Catherine; Fazio, Frank; Shanmugmam, Raghu; Tian, Liqing; Walhart, Tara; Wang, Yu; Allmon, Patricia; Perry, Scott; Schell, Sarah; Adams, Polly; Ward, Meghan; Meehl, Michaela; Akel, Salem; Poston, Leigh; Bag, Asim; Mack, Stephen; Klimo, Paul; Gajjar, Amar; Thomas, Paul; Crawford, Jeremy; Robinson, Giles; Park, Julie; Northcott, Paul; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher Share Save
Tumor inflammation-associated neurotoxicities for patients treated with intracranial B7-H3-CAR T cells on a phase I clinical trial Hanzlik, Emily M.; Bertrand, Kelsey C.; Chiang, Jason; Pinto, Soniya; Khan, Raja B.; Solanki, Arun; Selukar, Subodh; Wang, Yu; Bakare, Deborah; Swartz, Kate; Gajjar, Amar; Robinson, Giles W.; Park, Julie R.; Gottschalk, Stephen; Krenciute, Giedre; Derenzo, Christopher Share Save
Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target Ahmad, Shiekh Tanveer; Li, Yiran; Garcia-Lopez, Jesus; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Wu, Stephanie; Refaat, Alaa; Kojic, Marija; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Arnskotter, Frederik; Zindy, Frederique; Jones, Alun; Twarog, Nathaniel; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Lewis, Sara; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Shelat, Anang; Waszak, Sebastian; Kutscher, Lena; Lin, Hong; Northcott, Paul Share Save
Nuclear Transport as a Therapeutic Vulnerability in ZFTA-RELA Ependymoma Ippagunta, Siri; Arabzade, Amir; Varadharajan, Srinidhi; Emanus, Erik; Bland, Amanda; Kardian, Alisha; Laboe, Nicolas; Sun, Hua; Zheng, Tuyu; Orisme, Wilda; Johnson, Melissa; Rodgers, Britanny; Turner, Gregory; Steinberg, Jeffrey; Freeman, Burgess; Roussel, Martine; Shelat, Anang; Kriwacki, Richard; Merchant, Thomas; Deneen, Benjamin; Miller, Shondra; Kavirayani, Anoop Murthy; Ellison, David; Onar-thomas, Arzu; Robinson, Giles; Mack, Stephen; Bertrand, Kelsey Share Save
Molecular characterization of the SJMB12 clinical trial for children and young adults with newly diagnosed medulloblastoma Filipovic, David; Smith, Kyle; Dhanda, Sandeep; Strother, Doug; Fisher, Micheal J.; Bendel, Anne; Hwang, Eugene, I; Zhao, Sibo; Gottardo, Nicholas G.; Hassall, Timothy E. G.; Elster, Jennifer; Perreault, Sebastien; Ramaswamy, Vijay; Partap, Sonia; Laughton, Stephen; Cohn, Richard; Chintagumpala, Murali; Mccowage, Geoffrey; Sullivan, Michael; Sayour, Elias; Bowers, Daniel C.; Marks, Asher; Wright, Avery C.; Onar-Thomas, Arzu; Gajjar, Amar; Robinson, Giles W.; Northcott, Paul A. Share Save
INTEGRATED MULTI-OMIC PROFILING REVEALS PROTEOMIC HETEROGENEITY AND PATHWAY DYNAMICS IN MEDULLOBLASTOMA Li, Yiran; North, Kelsey; Lin, Hong; Wu, Stephine; Gudenas, Brian; Smith, Kyle; Yuan, Zuo-Fei; Soliman, Taha; Hadley, Jennifer; Batts, Melissa; Dhanda, Sandeep; Atkinson, Natasha; Mercer, Kimberly; High, Andy; Wang, Xusheng; Peng, Junmin; Roussel, Martine; Robinson, Giles; Orr, Brent; Northcott, Paul Share Save
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