James R. Woodgett - Publications, H-index & Citations

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James R. Woodgett

university of toronto

118H-index

456Paper Count

5.8WCitation Count

Published Papers 98

Publication Date

GSK3β-Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy

Advanced Science

IF14.1

2025-11-09

OAAI

Peiran Wang; Yedong Tang; Xueling Zhao; Yu Ni; Hualan Zhou; Enhao Zhang; Gaizhen Li; Han Cai; Yinan Wang; James R. Woodgett; Wenbo Deng; Haibin Wang; Zhongxian Lu; Haili Bao; Shuangbo Kong

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Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer

Cell Reports

IF6.9

2025-11-04

OAAI

Jeff C. Liu; Letizia Granieri; Mariusz Shrestha; Dong-Yu Wang; Ioulia Vorobieva; Elizabeth A. Rubie; Rob Jones; YoungJun Ju; Giovanna Pellecchia; Zhe Jiang; Carlo A. Palmerini; Yaacov Ben-David; Sean E. Egan; James R. Woodgett; Gary D. Bader; Alessandro Datti; Eldad Zacksenhaus

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Natural compound screening predicts novel GSK-3 isoform-specific inhibitors

BIOCHIMIE

IF3

2024-10-01

OAAI

Ahmad, Firdos; Gupta, Anamika; Marzook, Hezlin; Woodgett, James R.; Saleh, Mohamed A.; Qaisar, Rizwan

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Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer

NATURE COMMUNICATIONS

IF15.7

2023-07-18

OAAI

Jiang, Zhe; Ju, YoungJun; Ali, Amjad; Chung, Philip E. D.; Skowron, Patryk; Wang, Dong-Yu; Shrestha, Mariusz; Li, Huiqin; Liu, Jeff C.; Vorobieva, Ioulia; Ghanbari-Azarnier, Ronak; Mwewa, Ethel; Koritzinsky, Marianne; Ben-David, Yaacov; Woodgett, James R.; Perou, Charles M.; Dupuy, Adam; Bader, Gary D.; Egan, Sean E.; Taylor, Michael D.; Zacksenhaus, Eldad

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Tissue-specific role of glycogen synthase kinase 3β in glucose homeostasis and insulin action

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

249

OAAI

Patel, Satish; Doble, Bradley W.; MacAulay, Katrina; Sinclair, Elaine M.; Drucker, Daniel J.; Woodgett, James R.

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Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Khan, Kashif Aziz; Do, Florence; Marineau, Alexandre; Doyon, Priscilla; Clement, Jean-Francois; Woodgett, James R.; Doble, Bradley W.; Servant, Marc J.

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Mutational Analysis of Glycogen Synthase Kinase 3β Protein Kinase Together with Kinome-Wide Binding and Stability Studies Suggests Context-Dependent Recognition of Kinases by the Chaperone Heat Shock Protein 90

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Jin, Jing; Tian, Ruijun; Pasculescu, Adrian; Dai, Anna Yue; Williton, Kelly; Taylor, Lorne; Savitski, Mikhail M.; Bantscheff, Marcus; Woodgett, James R.; Pawson, Tony; Colwill, Karen

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Interactomes of Glycogen Synthase Kinase-3 Isoforms

JOURNAL OF PROTEOME RESEARCH

IF3.6

2023-02-13

OAAI

Cormier, Kevin W.; Larsen, Brett; Gingras, Anne-Claude; Woodgett, James R.

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Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart

CIRCULATION RESEARCH

IF16.2

2022-09-16

OAAI

Umbarkar, Prachi; Tousif, Sultan; Singh, Anand P.; Anderson, Joshua C.; Zhang, Qinkun; Tallquist, Michelle D.; Woodgett, James; Lal, Hind

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Specific Role for GSK3α in Limiting Long-Term Potentiation in CA1 Pyramidal Neurons of Adult Mouse Hippocampus

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2022-06-17

OAAI

Amini, Aeen Ebrahim; Miyata, Tsukiko; Lei, Gang; Jin, Fuzi; Rubie, Elizabeth; Bradley, Clarrisa A.; Woodgett, James R.; Collingridge, Graham L.; Georgiou, John

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Novel GSK-3 kinase inhibitor Pym-5 induces GSK-3β rather than GSK-3α-dependent melanogenesis in murine melanoma cells

JOURNAL OF DERMATOLOGICAL SCIENCE

IF4

2022-06-01

PREAI

Jia, Qi; Tao, Li; Zhou, Yinyin; Song, Li; Wei, Zhonghong; Lu, Tao; Woodgett, James R.; Lu, Yin

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GSK-3β Deficiency In Cardiomyocyte Induces Cardiac Progenitor Cell Proliferation In The Ischemic Heart

CIRCULATION RESEARCH

IF16.2

2021-09-03

PREAI

Yusuf, Ayesha; Qaisar, Rizwan; Woodgett, James R.; Ahmad, Firdos

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Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer

NATURE COMMUNICATIONS

IF15.7

2021-09-02

OAAI

Schachter, Nathan F.; Adams, Jessica R.; Skowron, Patryk; Kozma, Katelyn J.; Lee, Christian A.; Raghuram, Nandini; Yang, Joanna; Loch, Amanda J.; Wang, Wei; Kucharczuk, Aaron; Wright, Katherine L.; Quintana, Rita M.; An, Yeji; Dotzko, Daniel; Gorman, Jennifer L.; Wojtal, Daria; Shah, Juhi S.; Leon-Gomez, Paul; Pellecchia, Giovanna; Dupuy, Adam J.; Perou, Charles M.; Ben-Porath, Ittai; Karni, Rotem; Zacksenhaus, Eldad; Woodgett, Jim R.; Done, Susan J.; Garzia, Livia; Morrissy, A. Sorana; Reimand, Juri; Taylor, Michael D.; Egan, Sean E.

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Glycogen synthase kinase-3β inhibits tubular regeneration in acute kidney injury by a FoxM1-dependent mechanism

FASEB JOURNAL

IF4.2

2020-08-19

OAAI

Sinha, Sonali; Dwivedi, Nidhi; Woodgett, James; Tao, Shixin; Howard, Christianna; Fields, Timothy A.; Jamadar, Abeda; Rao, Reena

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GSK-3β Contributes to Parkinsonian Dopaminergic Neuron Death: Evidence From Conditional Knockout Mice and Tideglusib

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2020-06-03

OAAI

Li, Junyu; Ma, Shanshan; Chen, Jingnan; Hu, Kunhua; Li, Yongyi; Zhang, Zeyu; Su, Zixiang; Woodgett, James R.; Li, Mingtao; Huang, Qiaoying

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Molecular stratification within triple-negative breast cancer subtypes

SCIENTIFIC REPORTS

IF3.9

2019-12-13

OAAI

Wang, Dong-Yu; Jiang, Zhe; Ben-David, Yaacov; Woodgett, James R.; Zacksenhaus, Eldad

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A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells

CELLS

IF5.2

2019-10-29

OAAI

Kurgan, Nigel; Whitley, Kennedy C.; Maddalena, Lucas A.; Moradi, Fereshteh; Stoikos, Joshua; Hamstra, Sophie, I; Rubie, Elizabeth A.; Kumar, Megha; Roy, Brian D.; Woodgett, James R.; Stuart, Jeffrey A.; Fajardo, Val A.

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Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2019-05-01

OAAI

Ahmad, Firdos; Singh, Anand P.; Tomar, Dhanendra; Rahmani, Mohamed; Zhang, Qinkun; Woodgett, James R.; Tilley, Douglas G.; Lal, Hind; Force, Thomas

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A subgroup of microRNAs defines PTEN-deficient, triple-negative breast cancer patients with poorest prognosis and alterations in RB1, MYC, and Wnt signaling

BREAST CANCER RESEARCH

IF5.6

2019-01-31

OAAI

Wang, Dong-Yu; Gendoo, Deena M. A.; Ben-David, Yaacov; Woodgett, James R.; Zacksenhaus, Eldad

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Podocyte GSK3 is an evolutionarily conserved critical regulator of kidney function

NATURE COMMUNICATIONS

IF15.7

2019-01-24

OAAI

Hurcombe, J. A.; Hartley, P.; Lay, A. C.; Ni, L.; Bedford, J. J.; Leader, J. P.; Singh, S.; Murphy, A.; Scudamore, C. L.; Marquez, E.; Barrington, A. F.; Pinto, V.; Marchetti, M.; Wong, L. -F.; Uney, J.; Saleem, M. A.; Mathieson, P. W.; Patel, S.; Walker, R. J.; Woodgett, J. R.; Quaggin, S. E.; Welsh, G. I.; Coward, R. J. M.

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Research Directions