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Philipp J. Kahle

Eberhard Karls University Tuebingen

63H-index
172Paper Count
1.5WCitation Count
Published Papers 80
Publication Date
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The PET tracer [11C]MODAG-005 targets alpha-synuclein aggregates in the brain
errScience Translational Medicine
IF14.6
err2026-05-27
err0
PREAI
errRan Sing Saw; Sabrina Haas; Felix Schmidt; Sergey Ryazanov; Andrei Leonov; Daniel Bleher; Ann-Kathrin Grotegerd; Laura Kuebler; Benjamin Roeben; Fabian Schmidt; Matthias Reimold; Federica Bonanno; Viktoria C. Ruf; Bernadette Dahl; Christine M. Sandiego; Kelly E. Henry; Ioannis Papadopoulos; Martin Schaller; Philipp J. Kahle; Johannes Levin; Thomas Gasser; Kathrin Brockmann; Gerald Reischl; Christian la Fougère; Bernd J. Pichler; Andreas Maurer; Christian Griesinger; Armin Giese; Kristina Herfert
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Interactions of Oligodendrocyte Precursor Cells and Dopaminergic Neurons in the Mouse Substantia Nigra
errJOURNAL OF NEUROCHEMISTRY
IF4
err2025-01-27
err0
errOAAI
errFitzgerald, Julia C.; Sun, Ying; Reinecke, Frederek; Bauer, Elisabeth; Garaschuk, Olga; Kahle, Philipp J.
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errSave
Functional screening reveals genetic dependencies and diverging cell cycle control in atypical teratoid rhabdoid tumors
errGENOME BIOLOGY
IF9.4
err2024-12-02
err0
errOAAI
errMerk, Daniel J.; Tsiami, Foteini; Hirsch, Sophie; Walter, Bianca; Haeusser, Lara A.; Maile, Jens D.; Stahl, Aaron; Jarboui, Mohamed A.; Lechado-Terradas, Anna; Klose, Franziska; Babaei, Sepideh; Admard, Jakob; Casadei, Nicolas; Roggia, Cristiana; Spohn, Michael; Schittenhelm, Jens; Singer, Stephan; Schueller, Ulrich; Piccioni, Federica; Persky, Nicole S.; Claassen, Manfred; Tatagiba, Marcos; Kahle, Philipp J.; Root, David E.; Templin, Markus; Tabatabai, Ghazaleh
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errSave
A Novel PINK1 p.F385S Loss-of-Function Mutation in an Indian Family with Parkinson's Disease
errMOVEMENT DISORDERS
IF7.6
err2024-04-08
err1
errOAAI
errSharma, Karan; Kishore, Asha; Lechado-Terradas, Anna; Passannanti, Raffaele; Raimondi, Francesco; Sturm, Marc; Sreelatha, Ashwin Ashok Kumar; Puthenveedu, Divya Kalikavila; Sarma, Gangadhara; Casadei, Nicolas; Krueger, Rejko; Gasser, Thomas; Kahle, Philipp; Riess, Olaf; Fitzgerald, Julia C.; Sharma, Manu
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Proteomics elucidating physiological and pathological functions of TDP-43
errPROTEOMICS
IF3.9
err2023-09-06
err6
errOAAI
errGarcia Morato, Jorge; Gloeckner, Christian Johannes; Kahle, Philipp J.
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Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications (vol 297, 101339, 2021)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2023-08-01
err1
errOAAI
errTerradas, Anna Lechado; Zittlau, Katharina I.; Macek, Boris; Fraiberg, Milana; Elazar, Zvulun; Kahle, Philipp J.
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errSave
Failure of diet-induced transcriptional adaptations in alpha-synuclein transgenic mice
errHUMAN MOLECULAR GENETICS
IF3.2
err2022-08-24
err0
errOAAI
errKilzheimer, Alexander; Hentrich, Thomas; Rotermund, Carola; Kahle, Philipp J.; Schulze-Hentrich, Julia M.
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errSave
Signatures of glial activity can be detected in the CSF proteome
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-06-06
err13
errOAAI
errEninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan, I; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias; Kaeser, Stephan A.
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errSave
Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43
errNATURE COMMUNICATIONS
IF15.7
err2022-03-09
err37
errOAAI
errMorato, Jorge Garcia; Hans, Friederike; von Zweydorf, Felix; Feederle, Regina; Elsasser, Simon J.; Skodras, Angelos A.; Gloeckner, Christian Johannes; Buratti, Emanuele; Neumann, Manuela; Kahle, Philipp J.
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errSave
Temporal Analysis of Protein Ubiquitylation and Phosphorylation During Parkin-Dependent Mitophagy
errMOLECULAR & CELLULAR PROTEOMICS
IF5.5
err2022-02-01
err13
errOAAI
errZittlau, Katharina I.; Lechado-Terradas, Anna; Nalpas, Nicolas; Geisler, Sven; Kahle, Philipp J.; Macek, Boris
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errSave
Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications (vol 297, 101339, 2021 )
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-11-01
err0
errOAAI
errTerradas, Anna Lechado; Zittlau, Katharina I.; Macek, Boris; Fraiberg, Milana; Elazar, Zvulun; Kahle, Philipp J.
errShare
errSave
Intracranial administration of alpha-synuclein fibrils in A30P-synuclein transgenic mice causes robust synucleinopathy and microglial induction
errNEUROBIOLOGY OF AGING
IF3.5
err2021-10-01
err10
PREAI
errGentzel, Renee C.; Toolan, Dawn; Jinn, Sarah; Schachter, Joel B.; Ma, Lei; Kahle, Philipp J.; Smith, Sean M.; Marcus, Jacob N.
errShare
errSave
Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures
errMOLECULAR NEURODEGENERATION
IF17.5
err2021-08-11
err20
errOAAI
errBarth, Melanie; Bacioglu, Mehtap; Schwarz, Niklas; Novotny, Renata; Brandes, Janine; Welzer, Marc; Mazzitelli, Sonia; Haesler, Lisa M.; Schweighauser, Manuel; Wuttke, Thomas, V; Kronenberg-Versteeg, Deborah; Fog, Karina; Ambjorn, Malene; Alik, Ania; Melki, Ronald; Kahle, Philipp J.; Shimshek, Derya R.; Koch, Henner; Jucker, Mathias; Tanrioever, Gaye
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errSave
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
errEMBO MOLECULAR MEDICINE
IF8.3
err2021-07-26
err52
errOAAI
errEmmenegger, Marc; De Cecco, Elena; Hruska-Plochan, Marian; Eninger, Timo; Schneider, Matthias M.; Barth, Melanie; Tantardini, Elena; de Rossi, Pierre; Bacioglu, Mehtap; Langston, Rebekah G.; Kaganovich, Alice; Bengoa-Vergniory, Nora; Gonzalez-Guerra, Andres; Avar, Merve; Heinzer, Daniel; Reimann, Regina; Haesler, Lisa M.; Herling, Therese W.; Matharu, Naunehal S.; Landeck, Natalie; Luk, Kelvin; Melki, Ronald; Kahle, Philipp J.; Hornemann, Simone; Knowles, Tuomas P. J.; Cookson, Mark R.; Polymenidou, Magdalini; Jucker, Mathias; Aguzzi, Adriano
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Chronic-Progressive Dopaminergic Deficiency Does Not Induce Midbrain Neurogenesis
errCELLS
IF5.2
err2021-03-31
err3
errOAAI
errFauser, Mareike; Pan-Montojo, Francisco; Richter, Christian; Kahle, Philipp J.; Schwarz, Sigrid C.; Schwarz, Johannes; Storch, Alexander; Hermann, Andreas
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errSave
Medin aggregation causes cerebrovascular dysfunction in aging wild-type mice
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-09-08
err25
errOAAI
errDegenhardt, Karoline; Wagner, Jessica; Skodras, Angelos; Candlish, Michael; Koppelmann, Anna Julia; Wild, Katleen; Maxwell, Rusheka; Rotermund, Carola; von Zweydorf, Felix; Gloeckner, Christian Johannes; Davies, Hannah A.; Madine, Jillian; Del Turco, Domenico; Feederle, Regina; Lashley, Tammaryn; Deller, Thomas; Kahle, Philipp; Hefendehl, Jasmin K.; Jucker, Mathias; Neher, Jonas J.
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errSave
Prominent microglial inclusions in transgenic mouse models of α-synucleinopathy that are distinct from neuronal lesions
errACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
err2020-08-12
err21
errOAAI
errTanrioever, Gaye; Bacioglu, Mehtap; Schweighauser, Manuel; Mahler, Jasmin; Wegenast-Braun, Bettina M.; Skodras, Angelos; Obermueller, Ulrike; Barth, Melanie; Kronenberg-Versteeg, Deborah; Nilsson, K. Peter R.; Shimshek, Derya R.; Kahle, Philipp J.; Eisele, Yvonne S.; Jucker, Mathias
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errSave
Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2020-01-17
err38
errOAAI
errHans, Friederike; Glasebach, Hanna; Kahle, Philipp J.
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errSave
Ubiquitin-specific protease USP36 knockdown impairs Parkin-dependent mitophagy via downregulation of Beclin-1-associated autophagy-related ATG14L
errEXPERIMENTAL CELL RESEARCH
IF3.5
err2019-11-01
err28
PREAI
errGeisler, Sven; Jaeger, Lea; Golombek, Sonia; Nakanishi, Etsuro; Hans, Friederike; Casadei, Nicolas; Terradas, Anna Lechado; Linnemann, Caren; Kahle, Philipp J.
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Identification and characterization of ubiquitinylation sites in TAR DNA-binding protein of 43 kDa (TDP-43)
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2018-10-01
err35
errOAAI
errHans, Friederike; Eckert, Marita; von Zweydorf, Felix; Gloeckner, Christian Johannes; Kahle, Philipp J.
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Research Directions

No research directions
Co-authors
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