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SaveShare Save A framework for validating AI in precision medicine: considerations from the European ITFoC consortium
Tsopra, Rosy; Fernandez, Xose; Luchinat, Claudio; Alberghina, Lilia; Lehrach, Hans; Vanoni, Marco; Dreher, Felix; Sezerman, O. Ugur; Cuggia, Marc; de Tayrac, Marie; Miklasevics, Edvins; Itu, Lucian Mihai; Geanta, Marius; Ogilvie, Lesley; Godey, Florence; Boldisor, Cristian Nicolae; Campillo-Gimenez, Boris; Cioroboiu, Cosmina; Ciusdel, Costin Florian; Coman, Simona; Cubelos, Oliver Hijano; Itu, Alina; Lange, Bodo; Le Gallo, Matthieu; Lespagnol, Alexandra; Mauri, Giancarlo; Soykam, H. Okan; Rance, Bastien; Turano, Paola; Tenori, Leonardo; Vignoli, Alessia; Wierling, Christoph; Benhabiles, Nora; Burgun, Anita Share Save Treatment of metastatic uveal melanoma (mUM) through genomic profilingLeyvraz, S.; Schuette, M.; Kessler, T.; Risch, T.; Doerpholz, G.; Ochsenreither, S.; Rieke, D. T.; Amstislavskiy, V.; Wierling, C.; Klauschen, F.; Peuker, C. A.; Lamping, M.; Jelas, I.; Burock, S.; Schaefer, R.; Lange, B.; Ulrich, C.; Joussen, A.; Keilholz, U.; Yaspo, M-L. Share Save Unbiased phospho-proteomic profiling of mouse breast cancer models with DIA mass spectrometry refines CanPath prototype, a platform for predictive cancer pathway modelingBober, Magdalena; Banko-Bielecka, Monika; Heinzmann, Daniel; Rinner, Oliver; Dupuis, Nicholas; Wierling, Christoph; Li, Huaibiao; Kessler, Thomas; Muradyan, Artur; Kruetzfeldt, Louisa; Schuette, Moritz; Dreher, Felix; Ploubidou, Aspasia; Lange, Bodo Share Save Efficient Parameter Estimation Enables the Prediction of Drug Response Using a Mechanistic Pan-Cancer Pathway ModelFroehlich, Fabian; Kessler, Thomas; Weindl, Daniel; Shadrin, Alexey; Schmiester, Leonard; Hache, Hendrik; Muradyan, Artur; Schuette, Moritz; Lim, Ji-Hyun; Heinig, Matthias; Theis, Fabian J.; Lehrach, Hans; Wierling, Christoph; Lange, Bodo; Hasenauer, Jan Share Save Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinomaSternberg, Christina; Gruber, Wolfgang; Eberl, Markus; Tesanovic, Suzana; Stadler, Manuela; Elmer, Dominik P.; Schlederer, Michaela; Grund, Sandra; Roos, Simone; Wolff, Florian; Kaur, Supreet; Mangelberger, Doris; Lehrach, Hans; Hache, Hendrik; Wierling, Christoph; Laimer, Josef; Lackner, Peter; Wiederstein, Markus; Kasper, Maria; Risch, Angela; Petzelbauer, Peter; Moriggl, Richard; Kenner, Lukas; Aberger, Fritz Share Save CanPathPro-development of a platform for predictive pathway modelling using genetically engineered mouse modelsWierling, Christoph; Herault, Yann; Jonkers, Jos; Ploubidou, Aspasia; Frappart, Lucien; Hasenauer, Jan; Banga, Julio; Rinner, Oliver; Naumova, Valeriya; Koubi, David; Lange, Bodo Share Save Share Save Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitorsSchuette, Moritz; Risch, Thomas; Abdavi-Azar, Nilofar; Boehnke, Karsten; Schumacher, Dirk; Keil, Marlen; Yildirimman, Reha; Jandrasits, Christine; Borodina, Tatiana; Amstislavskiy, Vyacheslav; Worth, Catherine L.; Schweiger, Caroline; Liebs, Sandra; Lange, Martin; Warnatz, Hans-Joerg; Butcher, Lee M.; Barrett, James E.; Sultan, Marc; Wierling, Christoph; Golob-Schwarzl, Nicole; Lax, Sigurd; Uranitsch, Stefan; Becker, Michael; Welte, Yvonne; Regan, Joseph Lewis; Silvestrov, Maxine; Kehler, Inge; Fusi, Alberto; Kessler, Thomas; Herwig, Ralf; Landegren, Ulf; Wienke, Dirk; Nilsson, Mats; Velasco, Juan A.; Garin-Chesa, Pilar; Reinhard, Christoph; Beck, Stephan; Schaefer, Reinhold; Regenbrecht, Christian R. A.; Henderson, David; Lange, Bodo; Haybaeck, Johannes; Keilholz, Ulrich; Hoffmann, Jens; Lehrach, Hans; Yaspo, Marie-Laure Share Save Share Save Share Save Share Save Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cellsEberl, Markus; Klingler, Stefan; Mangelberger, Doris; Loipetzberger, Andrea; Damhofer, Helene; Zoidl, Kerstin; Schnidar, Harald; Hache, Hendrik; Bauer, Hans-Christian; Solca, Flavio; Hauser-Kronberger, Cornelia; Ermilov, Alexandre N.; Verhaegen, Monique E.; Bichakjian, Christopher K.; Dlugosz, Andrzej A.; Nietfeld, Wilfried; Sibilia, Maria; Lehrach, Hans; Wierling, Christoph; Aberger, Fritz Share Save A systems biology approach to deciphering the etiology of steatosis employing patient-derived dermal fibroblasts and iPS cellsJozefczuk, Justyna; Kashofer, Karl; Ummanni, Ramesh; Henjes, Frauke; Rehman, Samrina; Geenen, Suzanne; Wruck, Wasco; Regenbrecht, Christian; Daskalaki, Andriani; Wierling, Christoph; Turano, Paola; Bertini, Ivano; Korf, Ulrike; Zatloukal, Kurt; Westerhoff, Hans V.; Lehrach, Hans; Adjaye, James Share Save Share Save Share Save PROTEOMER: A workflow-optimized laboratory information management system for 2-D electrophoresis-centered proteomicsNebrich, Grit; Herrmann, Marion; Hartl, Daniela; Diedrich, Madeleine; Kreitler, Thomas; Wierling, Christoph; Klose, Joachim; Giavalisco, Patrick; Zabel, Claus; Mao, Lei Share Save Share Save Primary differentiation in the human blastocyst: Comparative molecular portraits of inner cell mass and trophectoderm cellsAdjaye, J; Huntriss, J; Herwig, R; BenKahla, A; Brink, TC; Wierling, C; Hultschig, C; Groth, D; Yaspo, ML; Picton, HM; Gosden, RG; Lehrach, H Share Save 
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