logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
D

Dennis J. Selkoe

harvard medical school

171H-index
674Paper Count
15.1WCitation Count
Published Papers 238
Publication Date
logo
Immunotherapy with B28, an antibody to Aβ oligomers, potently decreases amyloid plaques, microgliosis, and memory decline in APP knock-in mice
errCell Reports
IF6.9
err2026-06-30
err0
errOAAI
errTing Yang; Yi Ran Xu; Shaomin Li; Jean-Pierre Bellier; Youqi Tao; Anna E. Francis; Andrew M. Stern; Shanxue Jin; Beth L. Ostaszewski; Trebor L. Lawton; Laurent Pradier; David Reczek; Cynthia A. Lemere; Dominic M. Walsh; Dennis J. Selkoe
errShare
errSave
Plasma phosphorylated tau 217 and longitudinal trajectories of Aβ, tau, and cognition in cognitively unimpaired older adults
errNature Communications
IF15.7
err2026-04-14
err0
errOAAI
errHyun-Sik Yang; Juliana A. U. Anzai; Wai-Ying Wendy Yau; Brian C. Healy; Andrea M. Román Viera; Courtney Maa; Dylan Kirn; Michael J. Properzi; Jean-Pierre Bellier; Aaron P. Schultz; Michelle E. Farrell; Heidi I. L. Jacobs; Rachel F. Buckley; Kathryn V. Papp; Gad A. Marshall; Rebecca E. Amariglio; Dorene M. Rentz; Lei Liu; Dennis J. Selkoe; Philip B. Verghese; Joel B. Braunstein; Keith A. Johnson; Reisa A. Sperling; Jasmeer P. Chhatwal
errShare
errSave
Parkinson disease is a fatty acidopathy
errNature Reviews Neurology
IF33.1
err2025-10-01
err0
PREAI
errSaranna Fanning; Dennis Selkoe
errShare
errSave
Parkinson disease-associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neurons
errMOLECULAR BIOLOGY OF THE CELL
IF2.7
err2025-02-01
err0
PREAI
errClark, Karis A.; White, Andrew J.; Paslawski, Wojciech; Alexander, Kellianne D.; Peng, Shaoning; Young-Pearse, Tracy L.; Svenningsson, Per; Selkoe, Dennis J.; Ho, Gary P. H.
errShare
errSave
The pathogenicity of PSEN2 variants is tied to Aβ production and homology to PSEN1
errALZHEIMERS & DEMENTIA
IF11.1
err2024-11-19
err0
errOAAI
errLiu, Lei; Schultz, Stephanie A.; Saba, Adriana; Yang, Hyun-Sik; Li, Amy; Selkoe, Dennis J.; Chhatwal, Jasmeer P.
errShare
errSave
The case for regulatory approval of amyloid-lowering immunotherapies in Alzheimer's disease based on clearcut biomarker evidence
errALZHEIMERS & DEMENTIA
IF11.1
err2024-11-13
err0
errOAAI
errAisen, Paul; Bateman, Randall J.; Crowther, Damian; Cummings, Jeff; Dwyer, John; Iwatsubo, Takeshi; Kosco-Vilbois, Marie; Mcdade, Eric; Mohs, Richard; Scheltens, Philip; Sperling, Reisa; Selkoe, Dennis
errShare
errSave
Identification of fibrinogen as a plasma protein binding partner for lecanemab biosimilar IgG
errANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
IF3.9
err2024-10-30
err0
errOAAI
errBellier, Jean-Pierre; Viera, Andrea M. Roman; Christiano, Caitlyn; Anzai, Juliana A. U.; Moreno, Stephanie; Campbell, Emily C.; Godwin, Lucas; Li, Amy; Chen, Alan Y.; Alam, Sarah M.; Saba, Adriana; Yoo, Han Bin; Yang, Hyun-Sik; Chhatwal, Jasmeer P.; Selkoe, Dennis J.; Liu, Lei
errShare
errSave
Reducing the lipase LIPE in mutant α-synuclein mice improves Parkinson-like deficits and reveals sex differences in fatty acid metabolism
errNEUROBIOLOGY OF DISEASE
IF5.6
err2024-09-01
err2
errOAAI
errAdom, M. A.; Hahn, W. N.; Mccaffery, T. D.; Moors, T. E.; Zhang, X.; Svenningsson, P.; Selkoe, D. J.; Fanning, S.; Nuber, S.
errShare
errSave
RXR nuclear receptor signaling modulates lipid metabolism and triggers lysosomal clearance of alpha-synuclein in neuronal models of synucleinopathy
errCELLULAR AND MOLECULAR LIFE SCIENCES
IF6.2
err2024-08-20
err0
errOAAI
errTripathi, Arati; Alnakhala, Heba; Brontesi, Lisa; Selkoe, Dennis; Dettmer, Ulf
errShare
errSave
A stem cell-based assay platform demonstrates alpha-synuclein dependent synaptic dysfunction in patient-derived cortical neurons
errNPJ PARKINSONS DISEASE
IF8.2
err2024-05-21
err1
errOAAI
errWhite, Andrew J.; Clark, Karis A.; Alexander, Kellianne D.; Ramalingam, Nagendran; Young-Pearse, Tracy L.; Dettmer, Ulf; Selkoe, Dennis J.; Ho, Gary P. H.
errShare
errSave
The advent of Alzheimer treatments will change the trajectory of human aging
errNATURE AGING
IF19.4
err2024-04-19
err1
PREAI
errSelkoe, Dennis J.
errShare
errSave
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes (vol 10, 47, 2024)
errNPJ PARKINSONS DISEASE
IF8.2
err2024-03-12
err0
errOAAI
errNuber, Silke; Zhang, Xiaoqun; Mccaffery, Thomas D.; Moors, Tim E.; Adom, Marie-Alexandre; Hahn, Wolf N.; Martin, Dylan; Ericsson, Maria; Tripathi, Arati; Dettmer, Ulf; Svenningsson, Per; Selkoe, Dennis J.
errShare
errSave
Generation of G51D and 3D mice reveals decreased α-synuclein tetramer-monomer ratios promote Parkinson's disease phenotypes
errNPJ PARKINSONS DISEASE
IF8.2
err2024-02-29
err4
errOAAI
errNuber, Silke; Zhang, Xiaoqun; Mccaffery, Thomas D.; Moors, Tim E.; Adom, Marie-Alexandre; Hahn, Wolf N.; Martin, Dylan; Ericsson, Maria; Tripathi, Arathi; Dettmer, Ulf; Svenningsson, Per; Selkoe, Dennis J.
errShare
errSave
Uncovering elevated tau TPP motif phosphorylation in the brain of Alzheimer's disease patients
errALZHEIMERS & DEMENTIA
IF11.1
err2023-12-02
err1
errOAAI
errBellier, Jean-Pierre; Cai, Yuqi; Alam, Sarah M.; Wiederhold, Thorsten; Aiello, Arica; Vogelgsang, Jonathan S.; Berretta, Sabina; Chhatwal, Jasmeer P.; Selkoe, Dennis J.; Liu, Lei
errShare
errSave
Dynamic reversibility of α-synuclein serine-129 phosphorylation is impaired in synucleinopathy models
errEMBO REPORTS
IF6.2
err2023-10-23
err5
PREAI
errRamalingam, Nagendran; Brontesi, Lisa; Jin, Shan-Xue; Selkoe, Dennis J.; Dettmer, Ulf
errShare
errSave
Soluble oligomers or insoluble fibrils? Scientific commentary on Tau seeding and spreading in vivo is supported by both AD-derived fibrillar and oligomeric tau
errACTA NEUROPATHOLOGICA
IF9.3
err2023-09-21
err4
PREAI
errStern, Andrew M.; Selkoe, Dennis J.
errShare
errSave
Plasma NT1-tau and Aβ42 correlate with age and cognitive function in two large Down syndrome cohorts
errALZHEIMERS & DEMENTIA
IF11.1
err2023-07-12
err0
errOAAI
errStern, Andrew M.; Van Pelt, Kathryn L.; Liu, Lei; Anderson, Amirah K.; Ostaszewski, Beth; Mapstone, Mark; O'Bryant, Sid; Petersen, Melissa E.; Christian, Bradley T.; Handen, Benjamin L.; Selkoe, Dennis J.; Schmitt, Frederick; Head, Elizabeth
errShare
errSave
Abundant Aβ fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains
errNEURON
IF15
err2023-07-01
err30
errOAAI
errStern, Andrew M.; Yang, Yang; Jin, Shanxue; Yamashita, Keitaro; Meunier, Angela L.; Liu, Wen; Cai, Yuqi; Ericsson, Maria; Liu, Lei; Goedert, Michel; Scheres, Sjors H. W.; Selkoe, Dennis J.
errShare
errSave
Activation of ß2-adrenergic receptors prevents AD-type synaptotoxicity via epigenetic mechanisms
errMOLECULAR PSYCHIATRY
IF10.1
err2023-06-26
err1
PREAI
errJin, Ming; Wei, Zhiyun; Ramalingam, Nagendran; Xiao, Meng; Xu, Anqi; Yu, Xiaohan; Song, Qingyang; Liu, Wen; Zhao, Jianhua; Zhang, Dainan; Selkoe, Dennis J.; Li, Shaomin
errShare
errSave
Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer's disease
errTRENDS IN NEUROSCIENCES
IF15.1
err2023-06-01
err31
errOAAI
errYoung-Pearse, Tracy L.; Lee, Hyo; Hsieh, Yi-Chen; Chou, Vicky; Selkoe, Dennis J.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
F
Frank B. Hu
H-index: 244 · Papers: 1.9K
M
Meir J. Stampfer
H-index: 223 · Papers: 1.3K
D
Dennis W. Dickson
H-index: 218 · Papers: 2.3K
K
Kaj Blennow
H-index: 214 · Papers: 3.6K
J
John C. Morris
H-index: 212 · Papers: 2.4K
View more