logo
CanyamAI summaries for academic research
language
MobileMobile
  • Phone FeatureWeChat Mini Program
EnglishEnglish
noticeNotice
BlogBlog
delete
arrow
Back
G

George W. Sledge

caris life sciences

92H-index
1.0KPaper Count
4.5WCitation Count
Published Papers 206
Publication Date
logo
An Artificial Intelligence (AI) model integrating multiscale foundation model histopathology representations with molecular and clinical features predicts early and late distant recurrence in TAILORx
errnpj Breast Cancer
IF7.6
err2026-08-05
err0
errOAAI
errJoseph A. Sparano; Norsang Lama; Robert J. Gray; Md Ashequr Rahman; Victoria Wang; Della F. Makower; Yating Cheng; Sisi Shao; Kathy S. Albain; Eghbal Amidi; Ming Chen; Daniel F. Hayes; Anthony Helmstetter; Charles E. Geyer; Casey Bales; Andrew Hinton; Elizabeth C. Dees; Matthew P. Goetz; John A. Olson; Sunil S. Badve; Thomas J. Saphner; Timothy J. Whelan; Virginia G. Kaklaman; Matthew Oberley; Milan Radovich; David Spetzler; Eleftherios P. Mamounas; Norman Wolmark; George W. Sledge
errShare
errSave
Mechanisms of resistance to trastuzumab deruxtecan in breast cancer elucidated by multi-omic molecular profiling
errnpj Breast Cancer
IF7.6
err2025-12-20
err0
errOAAI
errGeorge W. Sledge; Joanne Xiu; Reshma L. Mahtani; Ana C. Sandoval Leon; Funda Meric-Bernstam; Jennifer R. Ribeiro; Ninad N. Kulkarni; Dileep R. Rampa; Jangsoon Lee; Naoto T. Ueno; Matthew J. Oberley; Milan Radovich; David B. Spetzler
errShare
errSave
EGFR amplification and PI3K pathway mutations identify a subset of breast cancers that synergistically respond to EGFR and PI3K inhibition
errOncogene
IF7.3
err2025-11-25
err0
errOAAI
errDavid J. Wisniewski; Donna Voeller; Yonit A. Addissie; Sachin Kumar Deshmukh; Sharon Wu; Maryam B. Lustberg; Darawalee Wangsa; Danny Wangsa; Kerstin Heselmeyer-Haddad; Yoshimi Endo Greer; George W. Sledge; Stanley Lipkowitz
errShare
errSave
Author Correction: Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer
errCommunications Medicine
IF6.3
err2025-10-24
err0
errOAAI
errYating Cheng; Norsang Lama; Ming Chen; Eghbal Amidi; Mohammadreza Ramzanpour; Md Ashequr Rahman; Joanne Xiu; Anthony Helmstetter; Lauren Dickman; Jennifer R. Ribeiro; Hassan Ghani; Matthew Oberley; David Spetzler; George W. Sledge
errShare
errSave
Comparison of trastuzumab deruxtecan and sacituzumab govitecan in HER2-negative metastatic breast cancer: a large real-world data analysis
errBreast Cancer Research
IF5.6
err2025-08-25
err0
PREAI
errGeorge W. Jr. Sledge; Joanne Xiu; Jeffrey Peter Solzak; Jennifer Ribeiro; Reshma L. Mahtani; Maryam B. Lustberg; Matthew J. Oberley; Milan Radovich; David Spetzler
errShare
errSave
Correction: Natural killer cell infiltration in prostate cancers predict improved patient outcomes
errProstate Cancer and Prostatic Diseases
IF5.8
err2025-08-12
err0
errOAAI
errNicholas A. Zorko; Allison Makovec; Andrew Elliott; Samuel Kellen; John R. Lozada; Ali T. Arafa; Martin Felices; Madison Shackelford; Pedro Barata; Yousef Zakharia; Vivek Narayan; Mark N. Stein; Kevin K. Zarrabi; Akash Patnaik; Mehmet A. Bilen; Milan Radovich; George Sledge; Wafik S. El-Deiry; Elisabeth I. Heath; Dave S. B. Hoon; Chadi Nabhan; Jeffrey S. Miller; Justin H. Hwang; Emmanuel S. Antonarakis
errShare
errSave
Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer
errCommunications Medicine
IF6.3
err2025-08-01
err0
errOAAI
errYating Cheng; Norsang Lama; Ming Chen; Egbhal Amidi; Mohammadreza Ramzanpour; Md Ashequr Rahman; Joanne Xiu; Anthony Helmstetter; Lauren Dickman; Jennifer R. Ribeiro; Hassan Ghani; Matthew Oberley; David Spetzler; George W. Sledge
errShare
errSave
Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach
errnpj Precision Oncology
IF8
err2025-07-30
err0
errOAAI
errEghbal Amidi; Mohammadreza Ramzanpour; Ming Chen; Tommy Boucher; Mukund Varma; Timothy Samec; Brian Lamon; Nicolas Stransky; Mark R. Miglarese; Matthew Oberley; David Spetzler; George W. Sledge
errShare
errSave
A 20-feature radiomic signature of triple-negative breast cancer identifies patients at high risk of death
errnpj Breast Cancer
IF7.6
err2025-07-26
err0
errOAAI
errHumaira Noor; Yuanning Zheng; Adam B. Mantz; Ryle Zhou; Andrew Kozlov; Wendy B. DeMartini; Shu-Tian Chen; Satoko Okamoto; Debra M. Ikeda; Melinda L. Telli; Allison W. Kurian; James M. Ford; Shaveta Vinayak; Mina Satoyoshi; Vishal Joshi; Sarah A. Mattonen; Kevin Lee; Olivier Gevaert; George W. Sledge; Haruka Itakura
errShare
errSave
REFINE: a database of linked clinical data and genomic biomarkers in renal cell carcinoma patients receiving immunotherapy-based treatment regimens
errONCOLOGIST
IF4.2
err2025-06-01
err0
errOAAI
errZhong, Jeffrey; Jang, Albert; Abuqayas, Bashar; Basu, Arnab; Benjamin, David J.; Bhatlapenumarthi, Vineel; Bilen, Mehmet Asim; Buch, Dhvani; Chang, Mark; Chin, Erica; Darabi, Sourat; Dhanikonda, Nagendra; Ghatalia, Pooja; Grigg, Claud M.; Grier, Abby L.; Jindal, Tanya; Jung, Joannah; Kilari, Deepak; Kumar, Hamsa L. S.; Lee, Suzanna; Neelands, Brittany; Pandya, Chinmayi; Pawalek, Jeff; Staggers, Jaimee; Yildirim, Ahmet; Zakharia, Yousef; Zarrabi, Kevin K.; Zimmerman, Michael; Sledge, George; Spetzler, David; Elliott, Andrew; McKay, Rana R.; Barata, Pedro C.
errShare
errSave
Identifying distinct prognostic and predictive contributions of tumor epithelium versus tumor microenvironment in colorectal cancer
errBMC CANCER
IF3.4
err2025-03-12
err0
errOAAI
errYang, Mingli; Nebozhyn, Michael V.; Schell, Michael J.; Gandhi, Nishant; Pflieger, Lance; Loboda, Andrey; Pledger, W. Jack; Soundararajan, Ramani; Maurin, Michelle; Wang, Heiman; Silva, Jetsen Rodriguez; Alden, Ashley; Coppola, Domenico; Elliott, Andrew; Sledge, George; Khushman, Moh'd; Lou, Emil; Goel, Sanjay; Yeatman, Timothy J.
errShare
errSave
Mutation burden and anti-PD-1 outcomes are not universally associated with immune cell infiltration or lymphoid activation
errCANCER CELL
IF44.5
err2024-12-01
err0
PREAI
errHsiehchen, David; Elliott, Andrew; Xiu, Joanne; Seeber, Andreas; El-Deiry, Wafik; Antonarakis, Emmanuel S.; Graff, Stephanie L.; Hall, Michael J.; Borghaei, Hossein; Hoon, Dave S. B.; V. Liu, Stephen; Ma, Patrick C.; Mckay, Rana R.; Wise-Draper, Trisha; Marshall, John; Sledge, George W.; Spetzler, David; Zhu, Hao
errShare
errSave
CYP2D6 activity in patients with metastatic breast cancer treated with single agent tamoxifen: results from ECOG-ACRIN E3108
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-10-21
err0
PREAI
errStearns, Vered; ONeill, Anne; Schneider, Bryan P.; Skaar, Todd C.; Liu, Minetta C.; Lohrisch, Caroline; Goetz, Matthew P.; Vallejos, Carlos S.; Sparano, Joseph A.; Villa, Diego; Silverman, Paula; Cheema, Puneet S.; Moore Jr, Dennis F.; Sledge, George W.
errShare
errSave
Genomic and transcriptomic landscape of HER2-low breast cancer
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-09-20
err0
PREAI
errBansal, Rani; Adeyelu, Tolulope; Elliott, Andrew; Walker, Phillip; Bustos, Matias A.; Rodriguez, Estelamari; Accordino, Melissa K.; Meisel, Jane; Gatti-Mays, Margaret E.; Hsu, Emily; Lathrop, Kate; Kaklamani, Virginia; Oberley, Matthew; Sledge, George; Sammons, Sarah L.; Graff, Stephanie L.
errShare
errSave
Temporal stability and chemotherapy responsiveness of classical and basal transcriptional subtypes of pancreatic cancer
errCANCER RESEARCH
IF16.6
err2024-09-15
err0
PREAI
errSingh, Harshabad; Xiu, Joanne; Kapner, Kevin; Yuan, Chen; Narayan, Raja R.; Oberley, Matthew; Farrell, Alex; Surana, Rishi; Huffmann, Brandon M.; Perez, Kimberly J.; Cleary, James M.; Jordan, Alexander C.; Costa, Andressa Dias; Williams, Hannah L.; Raghavan, Srivatsan; Weinberg, Benjamin; Pishvaian, Michael J.; Shroff, Rachna T.; Goel, Sanjay; Dougan, Stephanie K.; Nowak, Jonathan; Spetzler, David; Sledge, George; Wolpin, Brian M.; Aguirre, Andrew J.
errShare
errSave
Consensus molecular subtyping of metastatic colorectal cancer expands biomarker-directed therapeutic benefit for patients with CMS1 and CMS2 tumors
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-09-04
err0
PREAI
errChowdhury, Saikat; Xiu, Joanne; Ribeiro, Jennifer R.; Nicolaides, Theodore; Zhang, Jian; Korn, W. Michael; Poorman, Kelsey A.; Lenz, Heinz-Josef; Marshall, John L.; Oberley, Matthew J.; Sledge Jr, George W.; Spetzler, David; Kopetz, Scott; Shen, John Paul
errShare
errSave
Atlas of tertiary lymphoid structures in solid tumors: Genomic features and prediction of response to immunotherapy
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err1
PREAI
errItaliano, A.; Trent, J. C.; Sledge, G.; Xiu, J.; Antonarakis, E. S.; D'Amato, G.; Hsieh, D.; Elliott, A.
errShare
errSave
Metastatic hormone receptor-positive breast cancer outcomes in 628 patients with BRCA1, BRCA2, or PALB2 pathogenic variants: Real-world data analysis of genomics and targeted therapy sequencing
errANNALS OF ONCOLOGY
IF65.4
err2024-09-01
err0
PREAI
errParkinson, G.; Lustberg, M.; Nazari, S.; Elliott, A.; Sledge, G.; Jeselsohn, R.; Hsu, E.; Sobol, R. W.; Sandoval-Leon, A.; Gopalakrishnan, R.; Makhoul, I.; Nye, L. E.; Kurian, A.; Lynce, F.; Graff, S.
errShare
errSave
6th and 7th International consensus guidelines for the management of advanced breast cancer (ABC guidelines 6 and 7)
errBREAST
IF7.9
err2024-08-01
err22
errOAAI
errCardoso, Fatima; Paluch-Shimon, Shani; Schumacher-Wulf, Eva; Matos, Leonor; Gelmon, Karen; Aapro, Matti S.; Bajpai, Jyoti; Barrios, Carlos H.; Bergh, Jonas; Bergsten-Nordstrom, Elizabeth; Biganzoli, Laura; Cardoso, Maria Joao; Carey, Lisa A.; Chavez-MacGregor, Mariana; Chidebe, Runcie; Cortes, Javier; Curigliano, Giuseppe; Dent, Rebecca A.; El Saghir, Nagi S.; Eniu, Alexandru; Fallowfield, Lesley; Francis, Prudence A.; Millan, Sandra X. Franco; Gilchrist, Jenny; Gligorov, Joseph; Gradishar, William J.; Haidinger, Renate; Harbeck, Nadia; Hu, Xichun; Kaur, Ranjit; Kiely, Belinda; Kim, Sung-Bae; Koppikar, Smruti; Kuper-Hommel, Marion J. J.; Lecouvet, Frederic E.; Mason, Ginny; Mertz, Shirley A.; Mueller, Volkmar; Myerson, Claire; Neciosup, Silvia; Offersen, Birgitte, V; Ohno, Shinji; Pagani, Olivia; Partridge, Ann H.; Penault-Llorca, Frederique; Prat, Aleix; Rugo, Hope S.; Senkus, Elzbieta; Sledge, George W.; Swain, Sandra M.; Thomssen, Christoph; Vorobiof, Daniel A.; Vuylsteke, Peter; Wiseman, Theresa; Xu, Binghe; Costa, Alberto; Norton, Larry; Winer, Eric P.
errShare
errSave
A randomized phase III double-blind placebo-controlled trial of first-line chemotherapy and trastuzumab with or without bevacizumab for patients with HER2/neu-positive metastatic breast cancer: a trial of the ECOG-ACRIN Cancer Research Group (E1105)
errBREAST CANCER RESEARCH AND TREATMENT
IF3
err2024-07-05
err0
errOAAI
errMezzanotte-Sharpe, Jessica; ONeill, Anne; Mayer, Ingrid A.; Arteaga, Carlos L.; Yang, Ximing J.; Wagner, Lynne I.; Cella, David; Meropol, Neal J.; Alpaugh, R. Katherine; Saphner, Thomas J.; Swaney, Robert E.; Hoelzer, Karen L.; Gradishar, William J.; Abramson, Vandana G.; Sundaram, P. Kothai; Jilani, Shamim Z.; Perez, Edith A.; Lin, Nancy U.; Jahanzeb, Mohammad; Wolff, Antonio C.; Sledge, George W.; Reid, Sonya A.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
A
Adrian L. Harris
H-index: 187 · Papers: 2.1K
D
David Cella
H-index: 184 · Papers: 1.9K
D
Dirk Schadendorf
H-index: 182 · Papers: 2.4K
D
David R. Holmes
H-index: 177 · Papers: 2.1K
E
Eric P. Winer
H-index: 170 · Papers: 1.6K
View more