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Frailty and the risk of ICU-acquired infections in a randomised trial: a protocol and statistical analysis plan Fernando, Shannon M.; Muscedere, John; Rochwerg, Bram; Johnstone, Jennie; Daneman, Nick; Marshall, John C.; Lauzier, Francois; Rudkowski, Jill C.; Arabi, Yaseen M.; Heels-Ansdell, Diane; Sligl, Wendy; Kristof, Arnold S.; Duan, Erick; Dionne, Joanna C.; St-Arnaud, Charles; Reynolds, Steven; Khwaja, Kosar; Cook, Deborah J. Share Save
Coenrollment of critically ill patients in PROSPECT: characteristics and association with treatment efficacy and safety Thabane, Alex; Heels-Ansdell, Diane; Zytaruk, Nicole; Johnstone, Jennie; Lauzier, Francois; Arabi, Yaseen M.; Muscedere, John; Clarke, France; Hand, Lori; Watpool, Irene; Porteous, Rebecca; Sandu, Gyan; Santos, Marlene; Tassy, Danae; Marshall, John; Mcintyre, Lauralyn; Ball, Ian; Rochwerg, Bram; Karachi, Tim; Zarychanski, Ryan; Marquis, Francois; Friedrich, Jan O.; Lysecki, Paul; Cook, Deborah Share Save
Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trial Ong, Sean W. X.; Pinto, Ruxandra; Rishu, Asgar; Tong, Steven Y. C.; Commons, Robert J.; Conly, John M.; Evans, Gerald A.; Fralick, Michael; Kandel, Christopher; Lagace-Wiens, Philippe R. S.; Lee, Todd C.; Lother, Sylvain A.; Macfadden, Derek R.; Marshall, John C.; Martel-Laferriere, Valerie; Mayette, Michael; McDonald, Emily G.; Neary, John D.; Prazak, Josef; Raby, Edward; Regli, Adrian; Rogers, Benjamin A.; Smith, Stephanie; Taggart, Linda R.; Wang, Han Ting; Wuerz, Terence; Yahav, Dafna; Young, Paul J.; Fowler, Robert A.; Daneman, Nick Share Save
Impact of Antibiotic Duration on Gut Microbiome Composition and Antimicrobial Resistance: A Substudy of the BALANCE Randomized Controlled Trial Armstrong, Eric; Kulikova, Maria; Yee, Noelle; Rishu, Asgar; Muscedere, John; Sibley, Stephanie; Maslove, David; Boyd, J. Gordon; Evans, Gerald; Detsky, Michael; Marshall, John; Taggart, Linda R.; Friedrich, Jan O.; Tsang, Jennifer L. Y.; Duan, Erick; Firdous, Karim Ali; McCullagh, David; Findlater, Aidan; Fowler, Rob; Daneman, Nick; Coburn, Bryan Share Save
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Community versus academic hospital community-acquired pneumonia patients: a nested cohort study Tsang, Jennifer L. Y.; Rego, Kian; Binnie, Alexandra; Lee, Terry; Mccarthy, Anne; Cowan, Juthaporn; Archambault, Patrick; Lellouche, Francois; Turgeon, Alexis F.; Yoon, Jennifer; Lamontagne, Francois; Mcgeer, Allison; Douglas, Josh; Daley, Peter; Fowler, Robert; Maslove, David M.; Winston, Brent W.; Lee, Todd C.; Tran, Karen C.; Cheng, Matthew P.; Vinh, Donald C.; Boyd, John H.; Walley, Keith R.; Singer, Joel; Marshall, John C.; Haljan, Gregory; Jain, Fagun; Russell, James A. Share Save
From ICU Syndromes to ICU Subphenotypes Consensus Report and Recommendations for Developing Precision Medicine in the ICU Gordon, Anthony C.; Alipanah-Lechner, Narges; Bos, Lieuwe D.; Dianti, Jose; Diaz, Janet V.; Finfer, Simon; Fujii, Tomoko; Giamarellos-Bourboulis, Evangelos J.; Goligher, Ewan C.; Gong, Michelle Ng; Karakike, Eleni; Liu, Vincent X.; Lumlertgul, Nuttha; Marshall, John C.; Menon, David K.; Meyer, Nuala J.; Munroe, Elizabeth S.; Myatra, Sheila N.; Ostermann, Marlies; Prescott, Hallie C.; Randolph, Adrienne G.; Schenck, Edward J.; Seymour, Christopher W.; Shankar-Hari, Manu; Singer, Mervyn; Smit, Marry R.; Tanaka, Aiko; Taccone, Fabio S.; Thompson, B. Taylor; Torres, Lisa K.; van der Poll, Tom; Vincent, Jean-Louis; Calfee, Carolyn S. Share Save
What to Measure in Aneurysmal Subarachnoid Haemorrhage Research-An International Delphi Survey Andersen, Christopher R.; Presseau, Justin; Shea, Bev; Marti, Maria Luisa; McCoy, Madeline; Fernie, Gordon; McIntyre, Lauralyn; Delaney, Anthony; Chasse, Michael; Saigle, Victoria; Marshall, Shawn; Fergusson, Dean A.; Graham, Ian; Brehaut, Jamie; Turgeon, Alexis F.; Lauzier, Francois; Tugwell, Peter; Zha, Xiaohui; Talbot, Phil; Muscedere, John; Marshall, John C.; Thavorn, Kednapa; Griesdale, Donald; Lucas, Brenda; English, Shane W. Share Save
Stress Ulcer Prophylaxis during Invasive Mechanical Ventilation Cook, D.; Deane, A.; Lauzier, F.; Zytaruk, N.; Guyatt, G.; Saunders, L.; Hardie, M.; Heels-Ansdell, D.; Alhazzani, W.; Marshall, J.; Myburgh, J.; Muscedere, J.; English, S.; Arabi, Y. M.; Ostermann, M.; Knowles, S.; Hammond, N.; Byrne, K. M.; Chapman, M.; Venkatesh, B.; Young, P.; Rajbhandari, D.; Poole, A.; Al-Fares, A.; Reis, G.; Johnson, D.; Iqbal, M.; Hall, R.; Meade, M.; Hand, L.; Duan, E.; Clarke, F.; Dionne, J. C.; Tsang, J. L. Y.; Rochwerg, B.; Karachi, T.; Lamontagne, F.; D'Aragon, F.; St Arnaud, C.; Reeve, B.; Geagea, A.; Niven, D.; Vazquez-Grande, G.; Zarychanski, R.; Ovakim, D.; Wood, G.; Burns, K. E. A.; Goffi, A.; Wilcox, M. E.; Henderson, W.; Forrest, D.; Fowler, R.; Adhikari, N. K. J.; Ball, I; Mele, T.; Binnie, A.; Trop, S.; Mehta, S.; Morgan, I; Loubani, O.; Vanstone, M.; Fiest, K.; Charbonney, E.; Cavayas, Y. A.; Archambault, P.; Rewa, O. G.; Lau, V; Kristof, A. S.; Khwaja, K.; Williamson, D.; Kanji, S.; Sy, E.; Dennis, B.; Reynolds, S.; Marquis, F.; Lellouche, F.; Rahman, A.; Hosek, P.; Barletta, J. F.; Cirrone, R.; Tutschka, M.; Xie, F.; Billot, L.; Thabane, L.; Finfer, S. Share Save
The association of antiplatelet agents with mortality among patients with non-COVID-19 community-acquired pneumonia: a systematic review and meta-analysis Lother, Sylvain A.; Tennenhouse, Lana; Rabbani, Rasheda; Abou-Setta, Ahmed M.; Askin, Nicole; Turgeon, Alexis F.; Murthy, Srinivas; Houston, Brett L.; Houston, Donald S.; Mendelson, Asher A.; Paul, Jonathan D.; Farkouh, Michael E.; Hasmatali, Jovan; Rush, Barret; Nkosi, Joel; Goligher, Ewan C.; Rimmer, Emily; Marshall, John C.; Shaw, Souradet Y.; Lawler, Patrick R.; Keynan, Yoav; Zarychanski, Ryan Share Save
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The response of Canada's clinical health research ecosystem to the COVID-19 pandemic Lamontagne, Francois; Masse, Marie-Helene; Yarnell, Christopher; Camirand-Lemyre, Felix; Levesque, Simon; Domingue, Marie-Pier; O'Hearn, Katie; Watpool, Irene; Hoogenes, Jennifer; Sprague, Sheila; Menard, Julie; Lemaire-Paquette, Samuel; Hebert-Dufresne, Laurent; Cook, Deborah; Hebert, Paul; Rowan, Kathryn; Yada, Nicole; Menon, Kusum; Fowler, Robert; Fox-Robichaud, Alison; Boutin, Denis; Marshall, John; Kho, Michelle E. Share Save
Patient-important upper gastrointestinal bleeding in the ICU: A mixed-methods study of patient and family perspectives Vanstone, Meredith G.; Krewulak, Karla; Taneja, Shipra; Swinton, Marilyn; Fiest, Kirsten; Burns, Karen E. A.; Debigare, Sylvie; Dionne, Joanna C.; Guyatt, Gordon; Marshall, John C.; Muscedere, John G.; Deane, Adam M.; Finfer, Simon; Myburgh, John A.; Gouskos, Audrey; Rochwerg, Bram; Ball, Ian; Mele, Tina; Niven, Daniel J.; English, Shane W.; Verhovsek, Madeleine; Cook, Deborah J. Share Save
Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis Dennis, Brittany; Deane, Adam; Lauzier, Francois; Zytaruk, Nicole; Hardie, Miranda; Hammond, Naomi; Finfer, Simon; Arabi, Yaseen; Marshall, John; Saunders, Lois; Heels-Ansdell, Diane; Myburgh, John; Knowles, Serena; Muscedere, John; Ostermann, Marlies; Rajbhandari, Dorrilyn; English, Shane; Matic, Karlo; Venkatesh, Bala; Al Fares, Abdulrahman; Guyatt, Gordon; Alhazzani, Waleed; Mumtaz, Hassan; Poole, Alexis; Xie, Feng; Thabane, Lehana; Hall, Richard; Cook, Deborah Share Save
Reframing sepsis immunobiology for translation: towards informative subtyping andtargeted immunomodulatory therapies Shankar-Hari, Manu; Calandra, Thierry; Soares, Miguel P.; Bauer, Michael; Wiersinga, W. Joost; Prescott, Hallie C.; Knight, Julian C.; Baillie, Kenneth J.; Bos, Lieuwe D. J.; Derde, Lennie P. G.; Finfer, Simon; Hotchkiss, Richard S.; Marshall, John; Openshaw, Peter J. M.; Seymour, Christopher W.; Venet, Fabienne; Vincent, Jean-Louis; Le Tourneau, Christophe; Maitland-van der Zee, Anke H.; Mcinnes, Iain B.; van der Poll, Tom Share Save
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Efficacy and Safety of Umbilical Cord-Derived Mesenchymal Stromal Cell Therapy in Preclinical Models of Sepsis: A Systematic Review and Meta-analysis Hum, Christine; Tahir, Usama; Mei, Shirley H. J.; Champagne, Josee; Fergusson, Dean A.; Lalu, Manoj; Stewart, Duncan J.; Walley, Keith; Marshall, John; dos Santos, Claudia C.; Winston, Brent W.; Mendelson, Asher A.; Dave, Chintan; McIntyre, Lauralyn Share Save
Clinical phenotypes of cardiogenic shock survivors: insights into late host responses and long-term outcomes Soussi, Sabri; Ahmadiankalati, Mojtaba; Jentzer, Jacob C.; Marshall, John C.; Lawler, Patrick R.; Herridge, Margaret; Mebazaa, Alexandre; Gayat, Etienne; Lu, Zihang; dos Santos, Claudia C. Share Save