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R

Robert A. Hegele

western university (university of western ontario)

118H-index
1.2KPaper Count
7.3WCitation Count
Published Papers 596
Publication Date
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Promise of ANGPTL3 as a therapeutic target for controlling cholesterol levels
errExpert Opinion on Therapeutic Targets
IF4.4
err2026-05-12
err0
PREAI
errRobert A. Hegele
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Integration of a polygenic score into clinical risk prediction of atherosclerotic cardiovascular disease in familial hypercholesterolemia
errEuropean Journal of Preventive Cardiology
IF7.5
err2026-04-15
err0
PREAI
errMartine Paquette, MSc; Mark Trinder, MD, PhD; Isabelle Ruel, PhD; Simon-Pierre Guay, MD, PhD; Robert A Hegele, MD; Jacques Genest, MD; Liam R Brunham, MD, PhD; Alexis Baass, MD, MSc
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Zodasiran for cholesterol and triglyceride lowering in patients with hyperlipidemia: final report of phase 1 basket trial
errNature Medicine
IF50
err2026-04-07
err0
PREAI
errGerald F. Watts; Russell Scott; David Sullivan; John Baker; Peter Clifton; James Hamilton; Bruce Given; Stacey Melquist; Rong Zhou; Daniel Gaudet; Ira J. Goldberg; Joshua W. Knowles; Nicholas J. Leeper; Robert A. Hegele; Christie M. Ballantyne
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Update on familial hypercholesterolemia: an expert clinical consensus from the National Lipid Association
errJournal of Clinical Lipidology
IF4.6
err2026-01-29
err0
errOAAI
errZahid Ahmad; Anandita Agarwala; Marina Cuchel; P. Barton Duell; Robert A. Hegele; Lisa Hudgins; Allison Jamison; Dinesh Kalra; Amit Khera; Joshua W. Knowles; Iftikhar Kullo; Ana Morales; Mark A. Rothstein; Joseph J. Saseen; Daniel Soffer; Bruce A. Warden; William S. Weintraub; Lauren Williams; Anne C. Goldberg
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Nucleic acid based therapies — the next frontier in treating dyslipidemias
errCanadian Journal of Cardiology
IF5.3
err2026-01-23
err0
errOAAI
errRobert A. Hegele
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errSave
Evaluation of Pathogenic Variants Associated With Monogenic Disorders of Dyslipidemia in Patients With Well Characterised MASLD
errLiver International
IF5.2
err2026-01-09
err0
errOAAI
errSchwantes-an, Tae-hwi; Abreu, Marco A.; Neuschwander-tetri, Brent A.; Wang, Jian; Guo, Xiuqing; Tan, Jingyi; Hegele, Robert A.; Davidson, Nicholas O.; Lotta, Luca; Verweij, Niek; Yates, Katherine P.; Rotter, Jerome I.; Chalasani, Naga
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Genetic instruments and drug prediction: will APOC3 silencing reduce cardiovascular end points?
errEuropean Journal of Preventive Cardiology
IF7.5
err2026-01-01
err0
PREAI
errHegele, Robert A.
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errSave
Zodasiran, an RNAi therapeutic targeting ANGPTL3, for treating patients with homozygous familial hypercholesterolaemia (GATEWAY): an open-label, randomised, phase 2 trial
errThe Lancet Diabetes & Endocrinology
IF41.8
err2025-12-18
err0
PREAI
errFrederick J Raal; Jean Bergeron; Daniel Gaudet; Robert S Rosenson; David R Sullivan; Traci Turner; Robert A Hegele; Christie M Ballantyne; Joshua W Knowles; Nicholas J Leeper; Ira J Goldberg; Rong Zhou; Ma'an Muhsin; Jennifer Hellawell; James Hamilton; Gerald F Watts
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Spectrum of DNA Variants in Southwestern Ontario Patients with Familial Hypercholesterolemia
errCJC Open
IF1.9
err2025-12-01
err0
errOAAI
errLordfard, Sanaz; Wang, Jian; McIntyre, Adam D.; Kennedy, Brooke A.; Hegele, Robert A.
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errSave
Canadian Cardiovascular Society Clinical Practice Update on Cardiogenetic Testing
errCANADIAN JOURNAL OF CARDIOLOGY
IF5.3
err2025-12-01
err0
PREAI
errCare, Melanie; Arbour, Laura; Brunham, Liam R.; Christian, Susan; Gagnon, Johannie; Hegele, Robert A.; Jobling, Rebekah; Oudit, Gavin Y.; Roston, Thomas M.; Zahavich, Laura; Laksman, Zachary
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Imputation of Untreated LDL-C in Treated Subjects with Homozygous Familial Hypercholesterolaemia: An International Collaboration
errAtherosclerosis
IF5.7
err2025-11-19
err0
errOAAI
errG.B. John Mancini; Arnold Ryomoto; Isabelle Ruel; Iulia Iatan; Frederick J. Raal; Raul D. Santos; Ana Paula Marte; Robert A. Hegele; Brooke A. Kennedy; Liam R. Brunham; Daniel Gaudet; Miriam Larouche; Diane Brisson; Willemijn Schonck; Laurens F. Reeskamp; Jacques Genest
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errSave
Application of the NAFCS in Monogenic Hypertriglyceridemia Patients: A Single-Center Turkish Cohort Study
errJournal of Clinical Lipidology
IF4.6
err2025-11-08
err0
PREAI
errIlgin YILDIRIM SIMSIR; Oben BELEN; Pinar CIFTCI; Utku Erdem SOYALTIN; Su OZGUR; Ayca AYKUT; Haluk AKIN; Robert A. HEGELE
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The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR
errScience
IF45.8
err2025-10-30
err0
PREAI
errDaniel R. Tabet; Atina G. Coté; Megan C. Lancaster; Jochen Weile; Ashyad Rayhan; Iosifina Fotiadou; Nishka Kishore; Roujia Li; Da Kuang; Jennifer J. Knapp; Carmela S. Carrero; Olivia Taverniti; Anna Axakova; Jack M. P. Castelli; Mohammad M. Islam; Shahin Sowlati-Hashjin; Aanshi Gandhi; Ranim Maaieh; Michael Garton; Kenneth Matreyek; Douglas M. Fowler; Mafalda Bourbon; Simon G. Pfisterer; Andrew M. Glazer; Brett M. Kroncke; Victoria N. Parikh; Euan A. Ashley; Joshua W. Knowles; Melina Claussnitzer; Elizabeth T. Cirulli; Robert A. Hegele; Dan M. Roden; Calum A. MacRae; Frederick P. Roth
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Evolving guidelines on lipoprotein(a)
errCurrent Opinion in Lipidology
IF4.6
err2025-10-22
err0
PREAI
errBoffa, Michael B.a, b; Koschinsky, Marlys L.a, c; Hegele, Robert A.a, b, d
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Metabolic and vascular contributions to dementia: Soluble epoxide hydrolase-derived linoleic acid oxylipins and glycemic status are related to cerebral small vessel disease markers, atrophy, and cognitive performance
errAlzheimer's & Dementia
IF11.1
err2025-10-08
err0
errOAAI
errSi Won Ryoo; William Z. Lin; Alexandra Magliocco; Myuri Ruthirakuhan; Yuen Yan Wong; Sofia E. Perfetto; Celine Huang; Natasha Z. Anita; Stephen R. Arnott; Anthony E. Lang; Sean Symons; Robert A. Hegele; Maged Goubran; Joel Ramirez; Julie Ottoy; Jennifer S. Rabin; Bradley J. MacIntosh; Krista L. Lanctôt; Nuanyi Liang; Hugo Cogo-Moreira; Ameer Y. Taha; Walter Swardfager; the ONDRI Investigators
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P259 FAMILIAL HYPERCHOLESTEROLEMIA IN CANADA: SEX DIFFERENCES IN DIAGNOSIS, MANAGEMENT AND OUTCOMES FROM THE FH CANADA REGISTRY
errCanadian Journal of Cardiology
IF5.3
err2025-10-01
err0
PREAI
errI. Iatan; I. Ruel; L. Cermakova; P. Couture; J. Bergeron; A. Baass; D. Gaudet; B. McCrindle; G. Francis; G. Mancini; R. Hegele; J. Genest; L. Brunham
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P274 SOCIODEMOGRAPHIC AND CLINICAL CHARACTERISTICS ASSOCIATED WITH RECEIPT OF LP(A) TESTING IN ONTARIO: A POPULATION-BASED CROSS-SECTIONAL ANALYSIS
errCanadian Journal of Cardiology
IF5.3
err2025-10-01
err0
PREAI
errL. Colombo Godoy; N. Sule; A. Chu; T. Odugbemi; P. Austin; R. Lu; A. Odutayo; L. Brunham; P. Kavsak; I. Iatan; S. Goodman; G. Lewis; R. Hegele; D. Lee; D. Ko; J. Udell; H. Abdel-Qadir
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errSave
American Association of Clinical Endocrinology Consensus Statement: Algorithm for Management of Adults with Dyslipidemia – 2025 Update
errEndocrine Practice
IF4.6
err2025-09-12
err0
PREAI
errShailendra B. Patel; L. Maria Belalcazar; Samina Afreen; Ramiro Balderas; Robert A. Hegele; Fredrik Karpe; Carlos I. Ponte-Negretti; Aman Rajpal
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In Memoriam: J. David Spence (1944-2025)
errCanadian Journal of Cardiology
IF5.3
err2025-09-03
err0
PREAI
errRobert A. Hegele; Ross D. Feldman
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Brief Communication: Strong Concordance of the North American Familial Chylomicronemia Syndrome Score with a Positive Genetic Diagnosis in Patients from the Balance Study
errJournal of Clinical Lipidology
IF4.6
err2025-07-23
err0
errOAAI
errAlan S. Brown; Philippe Moulin; Andrew Dibble; Veronica J. Alexander; Lu Li; Daniel Gaudet; Joseph L. Witztum; Sotirios Tsimikas; Robert A. Hegele
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Research Directions

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