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Maintenance of neuronal TDP-43 expression requires axonal lysosome transport Ryan, Veronica H.; Lawton, Sydney; Reyes, Joel F.; Hawrot, James; Frankenfield, Ashley M.; Seddighi, Sahba; Ramos, Daniel M.; Epstein, Jacob; Faghri, Faraz; Johnson, Nicholas L.; Zou, Jizhong; Kampmann, Martin; Replogle, John; Qi, Yue Andy; Yuan, Hebao; Johnson, Kory; Maric, Dragan; Hao, Ling; Nalls, Mike A.; Ward, Michael Emmerson Share Save
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Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer's disease Long, Hua; Simmons, Adam; Mayorga, Arthur; Burgess, Brady; Nguyen, Tuan; Budda, Balasubrahmanyam; Rychkova, Anna; Rhinn, Herve; Tassi, Ilaria; Ward, Michael; Yeh, Felix; Schwabe, Tina; Paul, Robert; Kenkare-Mitra, Sara; Rosenthal, Arnon Share Save
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases (vol 19, 29, 2024) Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; DeTure, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjorn; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard Share Save
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes Pasquini, Lorenzo; Pereira, Felipe L.; Seddighi, Sahba; Zeng, Yi; Wei, Yongbin; Illan-Gala, Ignacio; Vatsavayai, Sarat C.; Friedberg, Adit; Lee, Alex J.; Brown, Jesse A.; Spina, Salvatore; Grinberg, Lea T.; Sirkis, Daniel W.; Bonham, Luke W.; Yokoyama, Jennifer S.; Boxer, Adam L.; Kramer, Joel H.; Rosen, Howard J.; Humphrey, Jack; Gitler, Aaron D.; Miller, Bruce L.; Pollard, Katherine S.; Ward, Michael E.; Seeley, William W. Share Save
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome Snyder, Allison; Ryan, Veronica H.; Hawrot, James; Lawton, Sydney; Ramos, Daniel M.; Qi, Y. Andy; Johnson, Kory R.; Reed, Xylena; Johnson, Nicholas L.; Kollasch, Aaron W.; Duffy, Megan F.; VandeVrede, Lawren; Cochran, J. Nicholas; Miller, Bruce L.; Toro, Camilo; Bielekova, Bibiana; Marks, Debora S.; Yokoyama, Jennifer S.; Kwan, Justin Y.; Cookson, Mark R.; Ward, Michael E. Share Save
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases Calliari, Anna; Daughrity, Lillian M.; Albagli, Ellen A.; Otero, Paula Castellanos; Yue, Mei; Jansen-West, Karen; Islam, Naeyma N.; Caulfield, Thomas; Rawlinson, Bailey; Deture, Michael; Cook, Casey; Graff-Radford, Neill R.; Day, Gregory S.; Boeve, Bradley F.; Knopman, David S.; Petersen, Ronald C.; Josephs, Keith A.; Oskarsson, Bjoern; Gitler, Aaron D.; Dickson, Dennis W.; Gendron, Tania F.; Prudencio, Mercedes; Ward, Michael E.; Zhang, Yong-Jie; Petrucelli, Leonard Share Save
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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD Seddighi, Sahba; Qi, Yue A.; Brown, Anna-Leigh; Wilkins, Oscar G.; Bereda, Colleen; Belair, Cedric; Zhang, Yong-Jie; Prudencio, Mercedes; Keuss, Matthew J.; Khandeshi, Aditya; Pickles, Sarah; Kargbo-Hill, Sarah E.; Hawrot, James; Ramos, Daniel M.; Yuan, Hebao; Roberts, Jessica; Sacramento, Erika Kelmer; Shah, Syed I.; Nalls, Mike A.; Colon-Mercado, Jennifer M.; Reyes, Joel F.; Ryan, Veronica H.; Nelson, Matthew P.; Cook, Casey N.; Li, Ziyi; Screven, Laurel; Kwan, Justin Y.; Mehta, Puja R.; Zanovello, Matteo; Hallegger, Martina; Shantaraman, Anantharaman; Ping, Lingyan; Koike, Yuka; Oskarsson, Bjorn; Staff, Nathan P.; Duong, Duc M.; Ahmed, Aisha; Secrier, Maria; Ule, Jernej; Jacobson, Steven; Reich, Daniel S.; Rohrer, Jonathan D.; Malaspina, Andrea; Dickson, Dennis W.; Glass, Jonathan D.; Ori, Alessandro; Seyfried, Nicholas T.; Maragkakis, Manolis; Petrucelli, Leonard; Fratta, Pietro; Ward, Michael E. Share Save
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia Marks, Jordan D.; Ayuso, Virginia Estades; Carlomagno, Yari; Yue, Mei; Todd, Tiffany W.; Hao, Ying; Li, Ziyi; McEachin, Zachary T.; Shantaraman, Anantharaman; Duong, Duc M.; Daughrity, Lillian M.; Jansen-West, Karen; Shao, Wei; Calliari, Anna; Bejarano, Jesus Gonzalez; DeTure, Michael; Rawlinson, Bailey; Casey, Monica Castanedes; Lilley, Meredith T.; Donahue, Megan H.; Jawahar, Vidhya Maheswari; Boeve, Bradley F.; Petersen, Ronald C.; Knopman, David S.; Oskarsson, Bjoern; Graff-Radford, Neill R.; Wszolek, Zbigniew K.; Dickson, Dennis W.; Josephs, Keith A.; Qi, Yue A.; Seyfried, Nicholas T.; Ward, Michael E.; Zhang, Yong-Jie; Prudencio, Mercedes; Petrucelli, Leonard; Cook, Casey N. Share Save
Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons (vol 18, 87, 2023) Hasan, Saadia; Fernandopulle, Michael S.; Humble, Stewart W.; Frankenfield, Ashley M.; Li, Haorong; Prestil, Ryan; Johnson, Kory R.; Ryan, Brent J.; Wade-Martins, Richard; Ward, Michael E.; Hao, Ling Share Save
A reproducible signature of cytoskeletal and ALS-related genes in human motoneurons Yadav, Archana; Matson, Kaya J. E.; Lee, Dylan; Alkaslasi, Mor R.; Roome, R. Brian; Ward, Michael E.; Phatnani, Hemali; Le Pichon, Claire E.; Menon, Vilas; Levine, Ariel J. Share Save
Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons Hasan, Saadia; Fernandopulle, Michael S.; Humble, Stewart W.; Frankenfield, Ashley M.; Li, Haorong; Prestil, Ryan; Johnson, Kory R.; Ryan, Brent J.; Wade-Martins, Richard; Ward, Michael E.; Hao, Ling Share Save
A fully automated FAIMS-DIA mass spectrometry-based proteomic pipeline Reilly, Luke; Lara, Erika; Ramos, Daniel; Li, Ziyi; Pantazis, Caroline B.; Stadler, Julia; Santiana, Marianita; Roberts, Jessica; Faghri, Faraz; Hao, Ying; Nalls, Mike A.; Narayan, Priyanka; Liu, Yansheng; Singleton, Andrew B.; Cookson, Mark R.; Ward, Michael E.; Qi, Yue A. Share Save
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