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An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function Kambali, Maltesh; Li, Yan; Unichenko, Petr; Pliego, Jessica A. Feria; Yadav, Rachita; Liu, Jing; McGuinness, Patrick; Cobb, Johanna G.; Wang, Muxiao; Nagarajan, Rajasekar; Lyu, Jinrui; Vongsouthi, Vanessa; Jackson, Colin J.; Engin, Elif; Coyle, Joseph T.; Shin, Jaeweon; Hodgson, Nathaniel W.; Hensch, Takao K.; Talkowski, Michael E.; Homanics, Gregg E.; Bolshakov, Vadim Y.; Henneberger, Christian; Rudolph, Uwe Share Save
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Impact of schizophrenia GWAS loci converge onto distinct pathways in cortical interneurons vs glutamatergic neurons during development Liu, Dongxin; Zinski, Amy; Mishra, Akanksha; Noh, Haneul; Park, Gun-Hoo; Qin, Yiren; Olorife, Oshoname; Park, James M.; Abani, Chiderah P.; Park, Joy S.; Fung, Janice; Sawaqed, Farah; Coyle, Joseph T.; Stahl, Eli; Bendl, Jaroslav; Fullard, John F.; Roussos, Panos; Zhang, Xiaolei; Stanton, Patric K.; Yin, Changhong; Huang, Weihua; Kim, Hae-Young; Won, Hyejung; Cho, Jun-Hyeong; Chung, Sangmi Share Save
Clinical evidence that a dysregulated master neural network modulator may aid in diagnosing schizophrenia Nomoto, Munetaka; Konopaske, Glenn T.; Yamashita, Naoya; Aoki, Reina; Jitsuki-Takahashi, Aoi; Nakamura, Haruko; Makihara, Hiroko; Saito, Mari; Saigusa, Yusuke; Nakamura, Fumio; Watanabe, Keisuke; Baba, Toshihiko; Benes, Francine M.; Tobe, Brian T. D.; Pernia, Cameron D.; Coyle, Joseph T.; Sidman, Richard L.; Hirayasu, Yoshio; Snyder, Evan Y.; Goshima, Yoshio Share Save
Dopaminergic neuromodulation of prefrontal cortex the NMDA D-serine Dallerac, Glenn; Li, Xia; Lecouflet, Pierre; Morisot, Nadege; Sacchi, Silvia; Asselot, Rachel; Thu Ha Pham; Potier, Brigitte; Watson, David J. G.; Schmidt, Staffan; Levasseur, Gregoire; Fossat, Pascal; Besedin, Andrey; Rivet, Jean-Michel; Coyle, Joseph T.; Collo, Ginetta; Pollegioni, Loredano; Kehr, Jan; Galante, Micaela; Fone, Kevin C.; Gardier, Alain M.; Freret, Thomas; Contarino, Angelo; Millan, Mark J.; Mothet, Jean-Pierre Share Save
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Targeted Treatment of Individuals With Psychosis Carrying a Copy Number Variant Containing a Genomic Triplication of the Glycine Decarboxylase Gene Bodkin, J. Alexander; Coleman, Michael J.; Godfrey, Laura J.; Carvalho, Claudia M. B.; Morgan, Charity J.; Suckow, Raymond F.; Anderson, Thea; Ongur, Dost; Kaufman, Marc J.; Lewandowski, Kathryn E.; Siegel, Arthur J.; Waldstreicher, Elliot; Grochowski, Christopher M.; Javitt, Daniel C.; Rujescu, Dan; Hebbring, Scott; Weinshilboum, Richard; Rodriguez, Stephanie Burgos; Kirchhoff, Colette; Visscher, Timothy; Vuckovic, Alexander; Fialkowski, Allison; McCarthy, Shane; Malhotra, Dheeraj; Sebat, Jonathan; Goff, Donald C.; Hudson, James I.; Lupski, James R.; Coyle, Joseph T.; Rudolph, Uwe; Levy, Deborah L. Share Save
Neurotoxic astrocytes express the D-serine synthesizing enzyme, serine racemase, in Alzheimer's disease Balu, Darrick T.; Pantazopoulos, Harry; Huang, Cathy C. Y.; Muszynski, Kevin; Harvey, Theresa Lynn; Uno, Yota; Rorabaugh, Jacki M.; Galloway, Claire R.; Botz-Zapp, Christian; Berretta, Sabina; Weinshenker, David; Coyle, Joseph T. Share Save
iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function (vol 25, pg 2873, 2020) Ni, Peiyan; Noh, Haneul; Park, Gun-Hoo; Shao, Zhicheng; Guan, Youxin; Park, James M.; Yu, Sophy; Park, Joy S.; Coyle, Joseph T.; Weinberger, Daniel R.; Straub, Richard E.; Cohen, Bruce M.; McPhie, Donna L.; Yin, Changhong; Huang, Weihua; Kim, Hae-Young; Chung, Sangmi Share Save
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