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Mikäel J. Pittet

agora cancer research center
H-index:92
Citation Count:5.0万
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Dendritic cells as programmable platforms for cancer immunotherapy

树突状细胞作为癌症免疫治疗的编程平台

Trends in Immunology
IF13.9
2026-09-160
OAAI
Yuchen Liu; Elodie Marcandalli; Yang Liu; Felix Bayerl; Mikael J. Pittet; Michele De Palma
Perioperative myeloid cell remodeling shapes CAR-T cell efficacy in glioblastoma

围术期髓系细胞重塑影响CAR-T细胞在胶质母细胞瘤中的疗效

Nature Communications
IF15.7
2026-07-310
OA
Martin Pedard; Luis Castillo Cantero; Ali Ghasemi; Eliana Marinari; Caterina Mollica; Suzel Davanture; Julie Pernot; Valérie Widmer; Doron Merkler; Kristof Egervari; Kark Schaller; Philippe Bijlenga; Andrea Bartoli; Shahan Momjian; Mikael J. Pittet; Valérie Dutoit; Denis Migliorini
Driving tumor-associated macrophages to a CXCL9Hi/SPP1Low phenotype eliminates pancreatic cancer

将肿瘤相关巨噬细胞驱动至CXCL9高表达/SPP1低表达表型可消除胰腺癌

Cell Reports Medicine
IF10.6
2026-07-230
OA
Yen T.M. Nguyen; Marc Pfefferlé; Juhyun Oh; Grant G. Simpson; Sierra A. Walker; Shingo Noguchi; Christopher S. Garris; Riley J. Deutsch-Williams; Pratyaksha Wirapati; Federico De Stefano; Marie Goemans; Rui Dai; Claudio Vinegoni; Carlos Fernández del Castillo; Andrew S. Liss; Mikael J. Pittet; Ralph Weissleder
Integrative analysis of transcriptomic data reveals a predictive gene signature for chemoradiotherapy response in rectal cancer

转录组数据的整合分析揭示了预测直肠癌化疗放疗反应的基因特征

iScience
IF4.1
2025-12-170
OAAI
Claudia Corrò; Joao Victor Machado Carvalho; Melivoia Rapti; Paolo Angelino; Matthieu Tihy; Arnaud Bakaric; Giacomo Puppa; Pratyaksha Wirapati; André Durham; Frederic Ris; Stephanie Tissot; Jonathan Thevenet; Inti Zlobec; Valérie Dutoit; Mikael Pittet; Petros Tsantoulis; Thibaud Koessler
Targeting cancer-associated fibroblasts for real-time intraoperative tumor identification with a spray-on fluorescent probe

靶向肿瘤相关成纤维细胞，利用喷洒式荧光探针实现实时术中肿瘤识别

Science Advances
IF12.5
2025-11-190
PRE
Riley J. Deutsch-Williams; Yuxuan Xie; Zachary Rabinowitz; Marie Goemans; Pratyaksha Wirapati; Claudio Vinegoni; Jonathan CT Carlson; Mikael Pittet; Ralph Weissleder
From complexity to consensus: A roadmap for neutrophil classification

从复杂性到共识：中性粒细胞分类的道路图

Immunity
IF26.3
2025-08-040
PRE
Lai Guan Ng; Ivan Ballesteros; Marco A. Cassatella; Mikala Egeblad; Zvi G. Fridlender; Dmitry Gabrilovich; Qiang Gao; Zvi Granot; Ricardo Grieshaber-Bouyer; H. Leighton Grimes; Catherine C. Hedrick; Andrés Hidalgo; Mariana J. Kaplan; Paul Kubes; Guang Sheng Ling; Liming Lu; Hongbo R. Luo; Tanya N. Mayadas; Niki M. Moutsopoulos; Melissa Ng; Peter A. Nigrovic; Renato Ostuni; Mikael J. Pittet; Daniela F. Quail; Carlos Silvestre-Roig; Oliver Soehnlein; Irina A. Udalova; Ruidong Xue; Ning Zhang; Immanuel Kwok
Myeloid cell networks govern re-establishment of original immune landscapes in recurrent ovarian cancer

髓系细胞网络调控复发性卵巢癌中原有免疫景观的重新建立

Cancer Cell
IF44.5
2025-07-310
OAAI
Eleonora Ghisoni; Fabrizio Benedetti; Aspram Minasyan; Mathieu Desbuisson; Paula Cunnea; Alizée J. Grimm; Noémie Fahr; Charlotte Capt; Nicolas Rayroux; Flavia De Carlo; Doga C. Gulhan; Julien Dagher; David Barras; Matteo Morotti; Juan A. Marín-Jiménez; Bovannak Stewen Chap; Tania Santoro; Giulia Spagnol; Mapi Fleury; Katerina Fortis; Julien Dorier; Mary K. Townsend; Stephanie Tissot; Sylvie Rusakiewicz; Humberto J. Ferreira; Anne I. Kraemer; Michal Bassani-Stenberg; Elizabeth M. Swisher; Lana A. Kandalaft; Spyridon A. Mastroyannis; Kathleen T. Montone; Daniel J. Powell; Susana Banerjee; Kathryn L. Terry; Shelley S. Tworoger; Mikaël J. Pittet; Janos L. Tanyi; George Coukos; Melissa A. Merritt; Christina Fotopoulou; Jose R. Conejo-Garcia; Denarda Dangaj Laniti
IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity

IL-1β阻断可预防肥胖小鼠模型中胰腺癌的化疗和免疫检查点阻断剂的心脏毒性，并提高其疗效。

JOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
2025-05-240
OA
Talele, Nilesh P.; Kumra, Heena; Gomes-Santos, Igor L.; Ho, William W.; Andersson, Patrik; Siwicki, Marie; Huang, Peigen; Duda, Dan G.; Pittet, Mikael J.; Fukumura, Dai; Jain, Rakesh K.
Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference

推动放射疗法-免疫疗法组合的界限: 第7届immunorad会议的亮点

ONCOIMMUNOLOGY
IF6.3
2024-12-180
OAAI
Laurent, Pierre-Antoine; Andre, Fabrice; Bobard, Alexandre; Deandreis, Desiree; Demaria, Sandra; Depil, Stephane; Eichmueller, Stefan B.; Fernandez-Palomo, Cristian; Foijer, Floris; Galluzzi, Lorenzo; Galon, Jerome; Guckenberger, Matthias; Harrington, Kevin J.; Herrera, Fernanda G.; Huber, Peter E.; Italiano, Antoine; Karam, Sana D.; Kroemer, Guido; Lambin, Philippe; Leuschner, Carola; Mantovani, Alberto; Meylan, Etienne; Mondini, Michele; Pittet, Mikael J.; Pouget, Jean-Pierre; Remon, Jordi; Sorensen, Claus S.; Sotiriou, Christos; Vanpouille-Box, Claire; Weichselbaum, Ralph R.; Welsh, James W.; Zitvogel, Laurence; Formenti, Silvia C.; Deutsch, Eric
Deep profiling of gene expression across 18 human cancers
NATURE BIOMEDICAL ENGINEERING
IF26.6
2024-12-171
PRE
Qiu, Wei; Dincer, Ayse B.; Janizek, Joseph D.; Celik, Safiye; Pittet, Mikael J.; Naxerova, Kamila; Lee, Su-In
Targeted SPP1 Inhibition of Tumor-Associated Myeloid Cells Effectively Decreases Tumor Sizes

靶向SPP1抑制肿瘤相关髓系细胞有效减小肿瘤大小

ADVANCED SCIENCE
IF14.1
2024-12-050
OA
Kartal, Benan; Garris, Christopher S.; Kim, Hyung Shik; Kohler, Rainer H.; Carrothers, Jasmine; Halabi, Elias A.; Iwamoto, Yoshiko; Goubet, Anne-Gaelle; Xie, Yuxuan; Wirapati, Pratyaksha; Pittet, Mikael J.; Weissleder, Ralph
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment

肿瘤微环境中T细胞麻痹的趋同诱导剂和效应物

NATURE REVIEWS CANCER
IF66.8
2024-10-240
PRE
Hanahan, Douglas; Michielin, Olivier; Pittet, Mikael J.
Epigenetic therapy modulates the tumor microenvironment to sensitize anti-PD-1 refractory head and neck cancers to immunotherapy

表观遗传疗法通过调节肿瘤微环境，使对PD-1耐药的头颈癌对免疫治疗更敏感。

ANNALS OF ONCOLOGY
IF65.4
2024-09-010
PRE
Pai, S.; Qin, T.; Mattox, A.; Campbell, J.; Park, J. C.; Shin, K-Y.; Sadow, P.; Faquin, W.; Haddad, R.; Pittet, M.; Garris, C.; Mempel, T.; Oneill, A.; Sartor, M.
GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model
FRONTIERS IN IMMUNOLOGY
IF5.9
2024-08-190
OAAI
Boersma, Bart; Puddinu, Viola; Huard, Arnaud; Fauteux-Daniel, Sebastien; Wirapati, Pratyaksha; Guedri, Sofia; Tille, Jean-Christophe; Mckee, Thomas; Pittet, Mikael; Palmer, Gaby; Bourquin, Carole
Unveiling the antitumor function of ID3 in liver macrophages
NATURE IMMUNOLOGY
IF27.6
2024-03-010
PRE
Goubet, Anne-Gaelle; Pittet, Mikael J.
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype
ADVANCED SCIENCE
IF14.1
2024-02-114
OAAI
Enbergs, Noah; Halabi, Elias A.; Goubet, Anne-Gaelle; Schleyer, Kelton; Fredrich, Ina R.; Kohler, Rainer H.; Garris, Christopher S.; Pittet, Mikael J.; Weissleder, Ralph
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanoma

对肿瘤浸润淋巴细胞过继治疗的反应与黑色素瘤中预先存在的CD8 T髓样细胞网络有关

SCIENCE IMMUNOLOGY
IF16.3
2024-02-0216
OA
Barras, David; Ghisoni, Eleonora; Chiffelle, Johanna; Orcurto, Angela; Dagher, Julien; Fahr, Noemie; Benedetti, Fabrizio; Crespo, Isaac; Grimm, Alizee J.; Morotti, Matteo; Zimmermann, Stefan; Duran, Rafael; Imbimbo, Martina; de Olza, Maria Ochoa; Navarro, Blanca; Homicsko, Krisztian; Bobisse, Sara; Labes, Danny; Tsourti, Zoe; Andriakopoulou, Charitini; Herrera, Fernanda; Petremand, Remy; Dummer, Reinhard; Berthod, Gregoire; Kraemer, Anne I.; Huber, Florian; Thevenet, Jonathan; Bassani-Sternberg, Michal; Schaefer, Niklaus; Prior, John O.; Matter, Maurice; Aedo, Veronica; Dromain, Clarisse; Corria-Osorio, Jesus; Tissot, Stephanie; Kandalaft, Lana E.; Gottardo, Raphael; Pittet, Mikael; Sempoux, Christine; Michielin, Olivier; Dafni, Urania; Trueb, Lionel; Harari, Alexandre; Laniti, Denarda Dangaj; Coukos, George
IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer
CANCER RESEARCH
IF16.6
2024-01-160
PRE
Talele, Nilesh P.; Kumra, Heena; Gomes-Santos, Igor L.; Roberge, Sylvie; Ho, William W.; Andersson, Patrick; Chatterjee, Sampurna; Siwicki, Marie; Duda, Dan G.; Pittet, Mikael J.; Fukumura, Dai; Jain, Rakesh K.
Review Dendritic cells as shepherds of T cell immunity in cancer

树突状细胞作为癌症T细胞免疫的牧羊人

IMMUNITY
IF26.3
2023-10-0147
OAAI
Pittet, Mikael J.; Di Pilato, Mauro; Garris, Christopher; Mempel, Thorsten R.
Clonal expansion of intra-epithelial T cells in breast cancer revealed by spatial transcriptomics
INTERNATIONAL JOURNAL OF CANCER
IF4.7
2023-06-126
OA
Romanens, Lou; Chaskar, Prasad; Marcone, Rachel; Ryser, Stephan; Tille, Jean-Christophe; Genolet, Raphael; Heimgartner-Hu, Ketty; Heimgartner, Killian; Moore, Jonathan S.; Liaudet, Nicolas; Kaya, Guerkan; Pittet, Mikael J.; Dietrich, Pierre-Yves; Delorenzi, Mauro; Speiser, Daniel E.; Harari, Alexandre; Tsantoulis, Petros; Labidi-Galy, Sana Intidhar

Research Directions

The data has not been retrieved yet.
R
Ralph Weissleder
H-index:200Papers:1,599Citations:17.1万
F
Filip K. Świrski
H-index:100Papers:275Citations:3.9万
M
Matthias Nahrendorf
H-index:119Papers:468Citations:5.1万
P
Pedro Romero
H-index:101Papers:676Citations:3.7万
C
Camilla Engblom
H-index:29Papers:80Citations:1.1万
R
Rainer H. Köhler
H-index:50Papers:184Citations:1.4万
C
Christina Pfirschke
H-index:27Papers:84Citations:1.1万
V
Virna Cortez‐Retamozo
H-index:24Papers:59Citations:7,999
J
Jean‐Charles Cerottini
H-index:63Papers:239Citations:1.3万
A
Alfred Zippelius
H-index:74Papers:551Citations:2.6万