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Lo-Yun Chen

chang gung university of science & technology

7H-index
43Paper Count
156Citation Count
Published Papers 22
Publication Date
Stereoselective AChE/BChE/BACE1 inhibition by enantiomeric norsesquiterpenoids with an unprecedented oxatricyclo[7.2.1.01,9]dodecane scaffold from the soft coral Sclerophytum humesi
err2026-05-23
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PREAI
errLuu, Phuong Vu; Nguyen, Cuong-Quoc; Ton-Nu, Huong Lien; Phan, Thuy-Tien Thi; Huynh, Quoc-Dung Tran; Pham, Ngoc-Thac; Le, Huong-Giang; Chen, Lo-Yun; Chang, Yu-Chia; Su, Jui-Hsin; Peng, Bo-Rong; Lai, Kuei-Hung
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UPLC-qToF-MS/MS analysis and anti-inflammatory activities of the soft coral Litophyton savignyi supported by bioactive molecular networking; network pharmacology; and molecular docking
err2026-03-04
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errOAAI
errShaimaa Fayez; Karim Abed; Mostafa S. Moussa; Lo-Yun Chen; Ting-Wei Liao; Tsong-Long Hwang; Po-Jen Chen; Mohamed El-Shazly; Kuei-Hung Lai
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Cembranoids from the cultured soft coral Sinularia sandensis
err2026-03-03
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errLai, Kuei-Hung; Liang, Chih-Yuan; Chen, You-Ying; Liao, Ting-Wei; Chen, Lo-Yun; Peng, Bo-Rong; Su, Jui-Hsin; El-Shazly, Mohamed
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Tissue-specific distribution of cytotoxic triterpene saponins in three Red Sea sea cucumbers
err2026-02-09
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errOAAI
errShaimaa Fayez; Karim Abed; Mostafa S. Moussa; Mennatallah N. Zohdy; Amira M. Ali; Miral A. El-Gohary; Mennatallah M. Awaad; Noura M. Alshawarby; Rana I. Sedky; Myar E. Taha; Toqa H. El-Sayed; Esraa M. Abd Elhamied; Nouran G. Mahmoud; Trivina E. Serafeem; Po-Jen Chen; Hui-Chi Huang; Lo-Yun Chen; Kuei-Hung Lai; Mohamed El-Shazly
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Briarane-Type Diterpenes from a Closed-System Cultured Soft Coral Briareum stechei
err2025-12-24
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PREAI
errLo-Yun Chen; Bo-Rong Peng; Thanh Hao Huynh; You-Ying Chen; Yu-Cheng Chen; Ngoc-Thac Pham; Huong-Giang Le; Quoc Vu Pham; Luu Vu Phuong; Ying-Mi Lai; Mohamed El-Shazly; Tsong-Long Hwang; Kuei-Hung Lai
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Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi
err2025-12-17
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PREAI
errPhuong Vu Luu; Thuy-Tien Thi Phan; Ngoc-Thac Pham; Huong-Giang Le; Lo-Yun Chen; Huong Lien Ton-Nu; Mei-Hsien Lee; Yao-An Shen; Yu-Jui Fan; Yu-Chia Chang; Jui-Hsin Su; Bo-Rong Peng; Kuei-Hung Lai
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SMART-assisted discovery of scalaranes from the marine sponge Lendenfeldia sp. and its anti-osteoclastogenesis activity
err2025-12-01
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PREAI
errPham, Quoc-Vu; Chang, Yu-Chia; Cheng, You-Song; Chen, Yun-Shiuan; Chen, Lo-Yun; Lee, Mei-Hsien; Su, Jui-Hsin; Peng, Bo-Rong; Lai, Kuei-Hung; Hwang, Tsong-Long
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Unusual diterpenoids featuring a 4/9-fused ring system from Sclerophytum humesi trigger intrinsic apoptosis via caspase-dependent PARP cleavage in pancreatic cancer
err2025-11-14
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PREAI
errPhuong Vu Luu; Bo-Rong Peng; Thuy-Tien Thi Phan; Cuong-Quoc Nguyen; Quoc-Dung Tran Huynh; Ngoc-Thac Pham; Huong-Giang Le; Lo-Yun Chen; Yao-An Shen; Yu-Jui Fan; Kuei-Hung Lai
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Rare and Underexplored Lobane- and Prenyleudesmane-Type Diterpenes Primarily from Corals with Additional Plant Sources—Biosynthesis and Pharmacological Perspectives
err2025-11-07
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PREAI
errLo-Yun Chen; Bo-Rong Peng; You-Ying Chen; Huong-Giang Le; Ngoc-Thac Pham; Yi-Ying Lin; Hung-Yi Chen; Pei-Jhen Hsieh; Mohamed El-Shazly; Kuei-hung Lai
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Bioassay-guided isolation of terpenoids from the soft coral Sclerophytum humesi and assessment of their antidiabetic and cytotoxic activities
err2025-09-22
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errOAAI
errPhuong Vu Luu; Quoc-Dung Tran Huynh; Ngoc-Thac Pham; Huong-Giang Le; Lo-Yun Chen; Cuong-Quoc Nguyen; Huong Lien Ton-Nu; Mei-Hsien Lee; Yu-Chia Chang; Jui-Hsin Su; Bo-Rong Peng; Kuei-Hung Lai
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Computational analysis of zoanthamine alkaloids from Zoanthus sp. as potential DKK1 and GSK-3β inhibitors for osteoporosis therapy via Wnt signaling
err2025-04-24
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errOAAI
errPham, Ngoc-Thac; Le, Huong-Giang; Peng, Bo-Rong; Chen, Lo-Yun; El-Shazly, Mohamed; Su, Jui-Hsin; Lee, Mei-Hsien
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Investigating the therapeutic potential of terpene metabolites in hot-natured herbal medicines and their mechanistic impact on circulatory disorders
err2025-02-01
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PREAI
errLe, Huong-Giang; Huynh, Thanh Hao; Peng, Bo-Rong; Pham, Ngoc-Thac; El-Shazly, Mohamed; Chen, Lo-Yun; Wang, Lung-Shuo; Yen, Pei-Tzu; Lai, Kuei-Hung
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Secondary metabolites of Alternaria alternate appraisal of their SARS-CoV-2 inhibitory and anti-inflammatory potentials
err2025-01-24
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errOAAI
errMoharram, Fatma A.; Ibrahim, Reham R.; Mahgoub, Shahenda; Abdel-Aziz, Mohamed S.; Said, Ahmed M.; Huang, Hui-Chi; Chen, Lo-Yun; Lai, Kuei-Hung; Hashad, Nashwa; Mady, Mohamed S.
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Unprecedented anti-inflammatory biscembranoids with 3-hydroperoxy-3-methylcyclohex-1-ene moiety isolated from aquaculture Sarcophyton trocheliophorum
err2023-12-01
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errPeng, Bo-Rong; Nguyen, Ngoc Bao An; Chen, Lo-Yun; El-Shazly, Mohamed; Hwang, Tsong-Long; Su, Jui-Hsin; Lai, Kuei-Hung
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Nor-24-homoscalaranes, Neutrophilic Inflammatory Mediators from the Marine Sponge Lendenfeldia sp.
err2023-09-06
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errOAAI
errPeng, Bo-Rong; Zheng, Li-Guo; Chen, Lo-Yun; El-Shazly, Mohamed; Hwang, Tsong-Long; Su, Jui-Hsin; Lee, Mei-Hsien; Lai, Kuei-Hung; Sung, Ping-Jyun
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Unlocking the Potential of Octocoral-Derived Secondary Metabolites against Neutrophilic Inflammatory Response
err2023-08-18
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errNguyen, Ngoc Bao An; El-Shazly, Mohamed; Chen, Po-Jen; Peng, Bo-Rong; Chen, Lo-Yun; Hwang, Tsong-Long; Lai, Kuei-Hung
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Quercus coccinea??????? Munchh leaves polyphenols: Appraisal acute lung injury induced by lipopolysaccharide in mice
err2023-08-01
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errEl-Sayed, Elsayed K.; Ibrahim, Reham R.; Ahmed, Asmaa A.; Khattab, Mohamed A.; Chen, Lo-Yun; Lai, Kuei-Hung; El Shaarawy, Fatheya S.; Tawfik, Nashwa F.; Moharram, Fatma A.
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Chemometric-guided chemical marker selection: A case study of the heat-clearing herb Scrophularia ningpoensis
err2023-03-17
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errWang, Lung-Shuo; Chen, Po-Jen; Cheng, Wen-Chi; Chang, Yu-Chia; El-Shazly, Mohamed; Chen, Lo-Yun; Peng, Bo-Rong; Su, Chun-Han; Yen, Pei-Tzu; Hwang, Tsong-Long; Lai, Kuei-Hung
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Towards Sustainable Medicinal Resources through Marine Soft Coral Aquaculture: Insights into the Chemical Diversity and the Biological Potential
err2022-10-14
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errNgoc Bao An Nguyen; Chen, Lo-Yun; El-Shazly, Mohamed; Peng, Bo-Rong; Su, Jui-Hsin; Wu, Ho-Cheng; Lee, I-Ta; Lai, Kuei-Hung
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Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte
err2022-09-05
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errOAAI
errWang, Shih-Han; Chen, Yi-Siao; Lai, Kuei-Hung; Lu, Chung-Kuang; Chang, Hsun-Shuo; Wu, Ho-Cheng; Yen, Feng-Lin; Chen, Lo-Yun; Lee, Jin-Ching; Yen, Chia-Hung
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