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Vahram Haroutunian

Icahn School of Medicine at Mount Sinai

107H-index
584Paper Count
7.6WCitation Count
Published Papers 138
Publication Date
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Single-nucleus atlas of cell-type specific genetic regulation in the human brain
errNature Genetics
IF29
err2026-09-23
err0
errOAAI
errBiao Zeng; Hui Yang; Prashant N. M; Sanan Venkatesh; Deepika Mathur; Pavan Auluck; David A. Bennett; Stefano Marenco; Vahram Haroutunian; Georgios Voloudakis; Donghoon Lee; John F. Fullard; Jaroslav Bendl; Kiran Girdhar; Gabriel E. Hoffman; Panos Roussos
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Single-nucleus transcriptome-wide association study of human brain disorders
errNature
IF48.5
err2026-09-23
err0
errOAAI
errSanan Venkatesh; Roman Kosoy; Zhenyi Wu; Marios Anyfantakis; Christian Dillard; Prashant N. M.; David Burstein; Deepika Mathur; Chris Chatzinakos; Bukola Ajanaku; Fotis Tsetsos; Biao Zeng; Sonali Gupta; Rachel Bercovitch; Aram Hong; Clara Casey; Marcela Alvia; Zhiping Shao; Stathis Argyriou; Karen Therrien; Tim Bigdeli; Pavan Auluck; David A. Bennett; Stefano Marenco; Vahram Haroutunian; Kiran Girdhar; Jaroslav Bendl; Donghoon Lee; John F. Fullard; Gabriel E. Hoffman; Georgios Voloudakis; Panos Roussos
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errSave
Single-cell atlas of transcriptomic vulnerability across brain disorders
errNature
IF48.5
err2026-09-23
err0
errOAAI
errDonghoon Lee; Mikaela Koutrouli; Nicolas Y. Masse; Gabriel E. Hoffman; Seon Kinrot; Xinyi Wang; Prashant N. M.; Milos Pjanic; Tereza Clarence; Fotios Tsetsos; Deepika Mathur; David Burstein; Karen Therrien; Aram Hong; Clara Casey; Zhiping Shao; Marcela Alvia; Stathis Argyriou; Jennifer Monteiro Fortes; Sarah R. Murphy; Pavel Katsel; Pavan K. Auluck; Lisa L. Barnes; Stefano Marenco; David A. Bennett; Lars Juhl Jensen; Kiran Girdhar; Georgios Voloudakis; Vahram Haroutunian; Jaroslav Bendl; John F. Fullard; Panos Roussos
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errSave
Lifespan single-cell transcriptomic atlas of the human prefrontal cortex
errNature
IF48.5
err2026-09-23
err0
errOAAI
errHui Yang; Tereza Clarence; Madeline R. Scott; Xinyi Wang; Prashant N. M.; Milos Pjanic; Sanan Venkatesh; Aram Hong; Clara Casey; Sarah R. Murphy; Zhiping Shao; Marcela Alvia; Stathis Argyriou; Alexander Kawah Yu; Nadejda M. Tsankova; Pavan K. Auluck; Stefano Marenco; Vahram Haroutunian; Georgios Voloudakis; Jaroslav Bendl; Colleen A. McClung; Donghoon Lee; John F. Fullard; Gabriel E. Hoffman; Kiran Girdhar; Panos Roussos
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errSave
Efficient differential expression analysis of large-scale single-cell transcriptomics data using Dreamlet
errNature Communications
IF15.7
err2026-09-23
err0
errOAAI
errGabriel E. Hoffman; Donghoon Lee; Jaroslav Bendl; N. M. Prashant; Aram Hong; Clara Casey; Marcela Alvia; Zhiping Shao; Stathis Argyriou; Karen Therrien; Sanan Venkatesh; Georgios Voloudakis; Vahram Haroutunian; John F. Fullard; Panos Roussos
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errSave
Plasticity of human microglia and brain perivascular macrophages in aging and Alzheimer’s disease
errNature Genetics
IF29
err2026-08-11
err0
PREAI
errDonghoon Lee; James M. Vicari; Christian Porras; Collin Spencer; Milos Pjanic; Xinyi Wang; Seon Kinrot; Philipp Weiler; Roman Kosoy; Jaroslav Bendl; Prashant N M; Konstantina Psychogyiou; Periklis Malakates; Evelyn Hennigan; Jennifer Monteiro Fortes; Shiwei Zheng; Karen Therrien; Deepika Mathur; Steven P. Kleopoulos; Zhiping Shao; Stathis Argyriou; Marcela Alvia; Clara Casey; Aram Hong; Kristin G. Beaumont; Robert Sebra; Christopher P. Kellner; David A. Bennett; Guo-Cheng Yuan; Georgios Voloudakis; Fabian J. Theis; Vahram Haroutunian; Gabriel E. Hoffman; John F. Fullard; Panos Roussos
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errSave
SECmeres outperform extracellular vesicles as potential blood RNA biomarkers for Alzheimer’s disease
errNature Communications
IF15.7
err2026-06-22
err0
errOAAI
errEdgar Gonzalez-Kozlova; Swapnil Tichkule; Yohei Nose; Tzu-Yi Chen; Eduard Reznik; Juliet V. Santiago; Anish Korrapati; Taliah Soleymani; Roman Kosoy; Igor Figueiredo; Donghoon Lee; Gabriel E. Hoffman; Natasha Kyprianou; Ronald E. Gordon; Carlos Cordon-Cardo; Srikant Rangaraju; Nicholas T. Seyfried; Vahram Haroutunian; John F. Fullard; Panos Roussos; Navneet Dogra
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errSave
Multi-omic expression of the VEGF family relates to Alzheimer's disease across diverse populations
erralzheimer's & dementia
IF0
err2026-01-28
err0
errOAAI
errJulia B. Libby; Kacie D. Deters; Nilüfer Ertekin-Taner; Minerva M. Carrasquillo; Mariet Allen; Philip De Jager; Vilas Menon; Bin Zhang; Vahram Haroutunian; Allan I. Levey; Nicholas T. Seyfried; Rima Kaddurah-Daouk; Steve Finkbeiner; Daifeng Wang; Anna K. Greenwood; Abby Vander Linden; Laura Heath; William L. Poehlman; Logan Dumitrescu; Vladislav A. Petyuk; David A. Bennett; Julie A. Schneider; Lisa L. Barnes; Timothy J. Hohman
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errSave
The neuronal chromatin landscape in brains from individuals with schizophrenia is linked to early fetal development
errNature Neuroscience
IF20
err2025-10-27
err0
PREAI
errKiran Girdhar; Jaroslav Bendl; Andrew Baumgartner; Karen Therrien; Sanan Venkatesh; Rachel Bercovitch; Deepika Mathur; Pengfei Dong; Samir Rahman; Steven P. Kleopoulos; Ruth Misir; Sarah M. Reach; Pavan K. Auluck; Stefano Marenco; David A. Lewis; Vahram Haroutunian; Cory C. Funk; Georgios Voloudakis; Gabriel E. Hoffman; John F. Fullard; Panos Roussos
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errSave
Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis
errCell
IF42.5
err2025-09-25
err0
errOAAI
errErming Wang; Kaiwen Yu; Jiqing Cao; Minghui Wang; Pavel Katsel; Won-min Song; Zhen Wang; Yuxin Li; Xusheng Wang; Qian Wang; Peng Xu; Gefei Yu; Li Zhu; Jia Geng; Parnian Habibi; Lu Qian; Tony Tuck; Aiqun Li; Julia TCW; Panos Roussos; Kristen J. Brennand; Vahram Haroutunian; Erik C.B. Johnson; Nicholas T. Seyfried; Allan I. Levey; David A. Bennett; Junmin Peng; Dongming Cai; Bin Zhang
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errSave
A multi-regional human brain atlas of chromatin accessibility and gene expression facilitates promoter-isoform resolution genetic fine-mapping
errNATURE COMMUNICATIONS
IF15.7
err2024-11-22
err0
errOAAI
errDong, Pengfei; Song, Liting; Bendl, Jaroslav; Misir, Ruth; Shao, Zhiping; Edelstien, Jonathan; Davis, David A.; Haroutunian, Vahram; Scott, William K.; Acker, Susanne; Lawless, Nathan; Hoffman, Gabriel E.; Fullard, John F.; Roussos, Panos
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CELL-TYPE SPECIFIC TRANSCRIPTOMIC PROFILING IN SCHIZOPHRENIA IDENTIFIES CHANGES IN GABAERGIC NEURONS AND OLIGODENDROCYTES AT TRANSCRIPT LEVEL
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2023-10-01
err0
PREAI
errMahoney, Rebecca; Bendl, Jaroslav; Kozlenkov, Alexey; Micallef, Courtney; Shao, Zhiping; Edelstien, Jonathan; Hoffman, Gabriel E.; Seoighe, Cathal; Morris, Derek W.; Haroutunian, Vahram; Dracheva, Stella; Fullard, John F.; Roussos, Panos
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Sex specific molecular networks and key drivers of Alzheimer's disease
errMOLECULAR NEURODEGENERATION
IF17.5
err2023-06-20
err18
errOAAI
errGuo, Lei; Cao, Jiqing; Hou, Jianwei; Li, Yonghe; Huang, Min; Zhu, Li; Zhang, Larry; Lee, Yeji; Duarte, Mariana Lemos; Zhou, Xianxiao; Wang, Minghui; Liu, Chia-Chen; Martens, Yuka; Chao, Michael; Goate, Alison; Bu, Guojun; Haroutunian, Vahram; Cai, Dongming; Zhang, Bin
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errSave
Lower levels of cortical [3H]pirenzepine binding to postmortem tissue defines a sub-group of older people with schizophrenia with less severe cognitive deficits
errSCHIZOPHRENIA RESEARCH
IF3.5
err2023-05-01
err7
PREAI
errDean, Brian; Haroutunian, Vahram; Scarr, Elizabeth
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Up-Regulation of S100 Gene Family in Brain Samples of a Subgroup of Individuals with Schizophrenia: Meta-analysis
errNEUROMOLECULAR MEDICINE
IF3.9
err2023-04-02
err2
PREAI
errShamir, Anat; Yitzhaky, Assif; Segev, Aviv; Haroutunian, Vahram; Katsel, Pavel; Hertzberg, Libi
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errSave
Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations
errNATURE GENETICS
IF31.8
err2023-03-13
err21
errOAAI
errLiu, Dongjing; Meyer, Dara; Fennessy, Brian; Feng, Claudia; Cheng, Esther; Johnson, Jessica; Park, You Jeong; Rieder, Marysia-Kolbe; Ascolillo, Steven; de Pins, Agathe; Dobbyn, Amanda; Lebovitch, Dannielle; Moya, Emily; Nguyen, Tan-Hoang; Wilkins, Lillian; Hassan, Arsalan; Aghanwa, Henry; Burdick, Katherine E.; Buxbaum, Joseph D.; Domenici, Enrico; Frangou, Sophia; Hartmann, Annette M.; Laurent-Levinson, Claudine; Malhotra, Dheeraj; Pato, Carlos N.; Pato, Michele T.; Ressler, Kerry; Roussos, Panos; Rujescu, Dan; Arango, Celso; Bertolino, Alessandro; Blasi, Giuseppe; Bocchio-Chiavetto, Luisella; Campion, Dominique; Carr, Vaughan; Fullerton, Janice M.; Gennarelli, Massimo; Gonzalez-Penas, Javier; Levinson, Douglas F.; Mowry, Bryan; Nimgaokar, Vishwajit L.; Pergola, Giulio; Rampino, Antonio; Cervilla, Jorge A.; Rivera, Margarita; Schwab, Sibylle G.; Wildenauer, Dieter B.; Daly, Mark; Neale, Benjamin; Singh, Tarjinder; O'Donovan, Michael C.; Owen, Michael J.; Walters, James T.; Ayub, Muhammad; Malhotra, Anil K.; Lencz, Todd; Sullivan, Patrick F.; Sklar, Pamela; Stahl, Eli A.; Huckins, Laura M.; Charney, Alexander W.; Aghanwa, Henry S.; Ansari, Moin; Asif, Aftab; Aslam, Rubina; Ayuso, Jose L.; Bigdeli, Tim; Bignotti, Stefano; Bobes, Julio; Bradley, Bekh; Buckley, Peter; Cairns, Murray J.; Catts, Stanley V.; Chaudhry, Abdul Rashid; Cohen, David; Collins, Brett L.; Consoli, Angele; Costas, Javier; Crespo-Facorro, Benedicto; Daskalakis, Nikolaos P.; Davidson, Michael; Davis, Kenneth L.; Dickerson, Faith; Dogar, Imtiaz A.; Drapeau, Elodie; Fananas, Lourdes; Fanous, Ayman; Fatima, Warda; Fatjo, Mar; Filippich, Cheryl; Friedman, Joseph; Fullard, John F.; Georgakopoulos, Penelope; Giannitelli, Marianna; Giegling, Ina; Green, Melissa J.; Guillin, Olivier; Gutierrez, Blanca; Handoko, Herlina Y.; Hansen, Stella Kim; Haroon, Maryam; Haroutunian, Vahram; Henskens, Frans A.; Hussain, Fahad; Jablensky, Assen V.; Junejo, Jamil; Kelly, Brian J.; Khan, Shams-Ud-Din A.; Khan, Muhammad N. S.; Khan, Anisuzzaman; Khawaja, Hamid R.; Khizar, Bakht; Kleopoulos, Steven P.; Knowles, James; Konte, Bettina; Kusumawardhani, Agung A. A. A.; Leghari, Naeemullah; Liu, Xudong; Lori, Adriana; Loughland, Carmel M.; Mahmood, Khalid; Mahmood, Saqib; Malaspina, Dolores; Malik, Danish; McNaughton, Amy; Michie, Patricia T.; Michopolous, Vasiliki; Molina, Esther; Molto, Maria D.; Munir, Asim; Muntane, Gerard; Naeem, Farooq; Nancarrow, Derek J.; Nasar, Amina; Nasr, Tanvir; Ohaeri, Jude U.; Ott, Jurg; Pantelis, Christos; Periyasamy, Sathish; Pinto, Ana G.; Powers, Abigail; Ramos, Belen; Rana, Nusrat H.; Rapaport, Mark; Reichenberg, Abraham; Saker-Delye, Safaa; Schall, Ulrich; Schofield, Peter R.; Scott, Rodney J.; Shanahan, Megan; Weickert, Cynthia Shannon; Sjaarda, Calvin; Smith, Heather J.; Suarez-Rama, Jose Javier; Tariq, Muhammad; Thibaut, Florence; Tooney, Paul A.; Umar, Muhammad; Vilella, Elisabet; Weiser, Mark; Wu, Jin Qin; Yolken, Robert
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Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease
errALZHEIMERS & DEMENTIA
IF11.1
err2023-02-22
err11
errOAAI
errWang, Erming; Wang, Minghui; Guo, Lei; Fullard, John F.; Micallef, Courtney; Bendl, Jaroslav; Song, Won-min; Ming, Chen; Huang, Yong; Li, Yuxin; Yu, Kaiwen; Peng, Junmin; Bennett, David A.; De Jager, Philip L.; Roussos, Panos; Haroutunian, Vahram; Zhang, Bin
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errSave
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
errNATURE GENETICS
IF31.8
err2022-09-26
err20
errOAAI
errDong, Pengfei; Hoffman, Gabriel E.; Apontes, Pasha; Bendl, Jaroslav; Rahman, Samir; Fernando, Michael B.; Zeng, Biao; Vicari, James M.; Zhang, Wen; Girdhar, Kiran; Townsley, Kayla G.; Misir, Ruth; Brennand, Kristen J.; Haroutunian, Vahram; Voloudakis, Georgios; Fullard, John F.; Roussos, Panos
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errSave
Brain atlas for glycoprotein hormone receptors at single-transcript level
errELIFE
IF0
err2022-09-02
err14
errOAAI
errRyu, Vitaly; Gumerova, Anisa; Korkmaz, Funda; Kang, Seong Su; Katsel, Pavel; Miyashita, Sari; Kannangara, Hasni; Cullen, Liam; Chan, Pokman; Kuo, TanChun; Padilla, Ashley; Sultana, Farhath; Wizman, Soleil A.; Kramskiy, Natan; Zaidi, Samir; Kim, Se-Min; New, Maria, I; Rosen, Clifford J.; Goosens, Ki A.; Frolinger, Tal; Haroutunian, Vahram; Ye, Keqiang; Lizneva, Daria; Davies, Terry F.; Yuen, Tony; Zaidi, Mone
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errSave
Genetics of the human microglia regulome refines Alzheimer's disease risk loci
errNATURE GENETICS
IF31.8
err2022-08-05
err49
errOAAI
errKosoy, Roman; Fullard, John F.; Zeng, Biao; Bendl, Jaroslav; Dong, Pengfei; Rahman, Samir; Kleopoulos, Steven P.; Shao, Zhiping; Humphrey, Jack; Lopes, Katia de Paiva; Charney, Alexander W.; Kopell, Brian H.; Raj, Towfique; Bennett, David; Kellner, Christopher P.; Haroutunian, Vahram; Hoffman, Gabriel E.; Roussos, Panos
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Research Directions

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Co-authors
Cooperation Journals
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John Q. Trojanowski
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Dennis W. Dickson
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John C. Morris
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Paul Greengard
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