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J

John M. Kirkwood

UPMC Hillman Cancer Center

137H-index
1.3KPaper Count
9.1WCitation Count
Published Papers 301
Publication Date
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Years of life lost in patients with a false-negative diagnosis of primary melanoma. A prospective study of the German Central Malignant Melanoma Registry involving 9063 patients over 28 years
errNature Communications
IF15.7
err2026-07-02
err0
errOAAI
errClaus Garbe; Ulrike Keim; Teresa Amaral; Paolo A. Ascierto; Jürgen Bauer; Reinhard Dummer; Alexander M. M. Eggermont; Thomas K. Eigentler; Lukas Flatz; Stephan Forchhammer; Andrea Forschner; Sara Gandini; Jeffrey E. Gershenwald; Axel Hauschild; Christoph Hoeller; John M. Kirkwood; Celeste Lebbe; Georgina V. Long; Paul Lorigan; Jason J. Luke; Friedegund Meier; Gisela Metzler; Paul Nathan; Michael A. Postow; Caroline Robert; Martin Röcken; Dirk Schadendorf; Benjamin Weide; David Whiteman; Ulrike Leiter; Peter Martus
errShare
errSave
Purinergic activity of circulating extracellular vesicles associates with disease progression in melanoma
errOncoImmunology
IF6.3
err2026-06-21
err0
errOAAI
errYana G. Najjar; Chang Sook Hong; Elizabeth V. Menshikova; John M. Kirkwood; Brenda Diergaarde; Edwin K. Jackson; Theresa L. Whiteside
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errSave
Serum Arginase-1 is a predictive biomarker for melanoma patients and a surrogate indicator of systemic myeloid cell fitness
errONCOIMMUNOLOGY
IF6.3
err2025-12-31
err0
PREAI
errBrand, Matthias; Adamik, Juraj; Wang, Hong; Sember, Sharon E.; Muzzio, Jennifer L.; Buffo, Mary J.; Sander, Cindy A.; Kirkwood, John M.; Ferris, Robert L.; Butterfield, Lisa H.; Vujanovic, Lazar
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errSave
A phase Ib/II study of modakafusp alfa alone and in combination with pembrolizumab in patients with advanced or metastatic solid tumors
errFrontiers in Oncology
IF3.3
err2025-12-09
err0
errOAAI
errDavid Gill; Charles L. Cowey; Gregory A. Daniels; David Sommerhalder; Raghad Abdul-Karim; John M. Kirkwood; Joanna Kolodney; Inderjit Mehmi; Rachel Roberts-Thomson; James Strauss; Sajeve Thomas; Eric Whitman; Yan Xing; Meredith McKean; Sabrina Collins; Cheryl Li; Gurpanna Saggu; Tian Chen; Shining Wang; Marina Lewis; Xavier Parot; Melissa Johnson
errShare
errSave
Image Biomarkers for Predicting Immunotherapy Response in Advanced Melanoma
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errKokenberger, Grant; Singh, Jatin; Yu, Tong; Meng, Xin; Hurd, Drew; Nguyen, Madison; McKay, William; Kirkwood, John M.; Zarour, Hassane M.; Davar, Diwakar; Pu, Jiantao
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errSave
Combination therapy with anti-LAG3 and anti-PD1 modulates immunosuppressive intratumoral CD4+regulatory T cells in metastatic melanoma
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errChukwuemeka, Prosper Obed; Karapetyan, Lilit; Sander, Cindy; Rush, Elizabeth; Rohatgi, Anjali; Bruno, Tullia Carmela; Workman, Creg; Kirkwood, John M.; Cillo, Anthony Richard; Vignali, Dario
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errSave
NK receptor signaling lowers the TCR activation threshold: role in selective recognition of cancer cells, but not healthy tissues, by TAA-specific CTLs
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errDong, Bowen; Obermajer, Natasa; Tsuji, Takemasa; Matsuzaki, Junko; Bonura, Cindy; Sander, Cindy; Withers, Henry; Long, Mark; Chavel, Colin A.; Olejniczak, Scott H.; Minderman, Hans; Kirkwood, John M.; Edwards, Robert P.; Storkus, Walter J.; Romero, Pedro; Kalinski, Pawel
errShare
errSave
Combinatorial therapy regimens targeting preclinical models of melanoma resistant to immune checkpoint blockade
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2025-09-16
err0
errOAAI
errKhan, Imran; Rodriguez-Brotons, Aida; Bhattacharjee, Anukana; Bezrookove, Vladimir; Dar, Altaf; De Semir, David; Nosrati, Mehdi; Ice, Ryan; Soroceanu, Liliana; Leong, Stanley P.; Kim, Kevin B.; Shi, Yihui; Cleaver, James E.; Iii, James R. Miller; Desprez, Pierre-Yves; Kirkwood, John M.; Bosenberg, Marcus; Salomonis, Nathan; McAllister, Sean; Kashani-Sabet, Mohammed
errShare
errSave
Surprising role of CMV in shaping outcomes of immunotherapy for melanoma — chronic infection yields favourable survival
errNature Reviews Clinical Oncology
IF82.2
err2025-08-05
err0
PREAI
errAnthony R. Cillo; John M. Kirkwood
errShare
errSave
Intratumoral vidutolimod as monotherapy or in combination with pembrolizumab in patients with programmed cell death 1 blockade–resistant melanoma: Final analysis from a phase 1b study
errCancer
IF5.1
err2025-08-03
err0
errOAAI
errMohammed M. Milhem MD; Yousef Zakharia MD; Diwakar Davar MD, MSc; Elizabeth I. Buchbinder MD; Theresa Medina MD; Adil Daud MD; Antoni Ribas MD, PhD; Bartosz Chmielowski MD, PhD; Jiaxin Niu MD, PhD; Geoffrey T. Gibney MD; Kim Margolin MD, FASCO; Anthony J. Olszanski RPh, MD; Inderjit Mehmi MD; Takami Sato MD, PhD; Montaser Shaheen MD; Luping Zhao PhD; Heather Kelley MA; Hong Liu PhD; Sujatha Kumar PhD; Dmitri Bobilev MD; Arthur M. Krieg MD; James E. Wooldridge MD; John M. Kirkwood MD
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errSave
Response to letter to the editor on “Patient-reported outcomes with adjuvant nivolumab versus placebo after complete resection of stage IIB/C melanoma in the randomized phase 3 CheckMate 76K trial”
errEuropean Journal of Cancer
IF7.1
err2025-07-13
err0
PREAI
errJohn M. Kirkwood
errShare
errSave
Patient-reported outcomes with adjuvant nivolumab versus placebo after complete resection of stage IIB/C melanoma in the randomized phase 3 CheckMate 76 K trial
errEUROPEAN JOURNAL OF CANCER
IF7.1
err2025-05-01
err0
errOAAI
errKirkwood, John M.; Mohr, Peter; Hoeller, Christoph; Grob, Jean-Jacques; Del Vecchio, Michele; Lord-Bessen, Jennifer; Srinivasan, Swetha; Nassar, Ayman; Campigotto, Federico; Fairbanks, Hannah; Taylor, Fiona; Lawrance, Rachael; Long, Georgina, V; Weber, Jeffrey
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errSave
Dysfunctional CD11c-CD21- extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-02-19
err0
PREAI
errRuffin, Ayana T.; Casey, Allison N.; Kunning, Sheryl R.; Macfawn, Ian P.; Liu, Zhentao; Arora, Charu; Rohatgi, Anjali; Kemp, Felicia; Lampenfeld, Caleb; Somasundaram, Ashwin; Rappocciolo, Giovanna; Kirkwood, John M.; Duvvuri, Umamaheswar; Seethala, Raja; Bao, Riyue; Huang, Yufei; Cillo, Anthony R.; Ferris, Robert L.; Bruno, Tullia C.
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errSave
Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma: Outcomes in histopathologic subgroups from the randomized, double-blind, phase 3 KEYNOTE-716 trial
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2024-03-13
err1
errOAAI
errSchadendorf, Dirk; Luke, Jason John; Ascierto, Paolo A.; Long, Georgina, V; Rutkowski, Piotr; Khattak, Adnan; Del Vecchio, Michele; de la Cruz-Merino, Luis; Mackiewicz, Jacek; Sileni, Vanna Chiarion; Kirkwood, John M.; Robert, Caroline; Grob, Jean-Jacques; Dummer, Reinhard; Carlino, Matteo S.; Zhao, Yujie; Kalabis, Mizuho; Krepler, Clemens; Eggermont, Alexander; Scolyer, Richard A.
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errSave
Plain language summary of the CheckMate 76K study results: nivolumab given after stage 2B/2C melanoma is removed by surgery
errFUTURE ONCOLOGY
IF2.6
err2024-02-23
err1
errOAAI
errKirkwood, John M.; Del Vecchio, Michele; Weber, Jeffrey; Hoeller, Christoph; Grob, Jean-Jacques; Mohr, Peter; Loquai, Carmen; Dutriaux, Caroline; Chiarion-Sileni, Vanna; Mackiewicz, Jacek; Rutkowski, Piotr; Arenberger, Petr; Quereux, Gaelle; Meniawy, Tarek M.; Ascierto, Paolo A.; Menzies, Alexander M.; Durani, Piyush; Lobo, Maurice; Campigotto, Federico; Gastman, Brian; Long, Georgina, V
errShare
errSave
Adjuvant nivolumab in resected stage IIB/C melanoma: primary results from the randomized, phase 3 CheckMate 76K trial (vol 29, pg 2835, 2023)
errNATURE MEDICINE
IF50
err2024-01-04
err0
errOAAI
errKirkwood, John M.; Del Vecchio, Michele; Weber, Jeffrey; Hoeller, Christoph; Grob, Jean-Jacques; Mohr, Peter; Loquai, Carmen; Dutriaux, Caroline; Chiarion-Sileni, Vanna; Mackiewicz, Jacek; Rutkowski, Piotr; Arenberger, Petr; Quereux, Gaelle; Meniawy, Tarek M.; Ascierto, Paolo A.; Menzies, Alexander M.; Durani, Piyush; Lobo, Maurice; Campigotto, Federico; Gastman, Brian; Long, Georgina V.
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errSave
Three-Year Overall Survival with Tebentafusp in Metastatic Uveal Melanoma
errNEW ENGLAND JOURNAL OF MEDICINE
IF78.5
err2023-12-14
err49
errOAAI
errHassel, Jessica C.; Piperno-Neumann, Sophie; Rutkowski, Piotr; Baurain, Jean-Francois; Schlaak, Max; Butler, Marcus O.; Sullivan, Ryan J.; Dummer, Reinhard; Kirkwood, John M.; Orloff, Marlana; Sacco, Joseph J.; Ochsenreither, Sebastian; Joshua, Anthony M.; Gastaud, Lauris; Curti, Brendan; Piulats, Josep M.; Salama, April K. S.; Shoushtari, Alexander N.; Demidov, Lev; Milhem, Mohammed; Chmielowski, Bartosz; Kim, Kevin B.; Carvajal, Richard D.; Hamid, Omid; Collins, Laura; Ranade, Koustubh; Holland, Chris; Pfeiffer, Constance; Nathan, Paul
errShare
errSave
Adjuvant nivolumab in resected stage IIB/C melanoma: primary results from the randomized, phase 3 CheckMate 76K trial (16 OCT, 10.1038/s41591-023-02583-2, 2023 )
errNATURE MEDICINE
IF50
err2023-11-03
err0
errOAAI
errKirkwood, John M.; Del Vecchio, Michele; Weber, Jeffrey; Hoeller, Christoph; Grob, Jean-Jacques; Mohr, Peter; Loquai, Carmen; Dutriaux, Caroline; Chiarion-Sileni, Vanna; Mackiewicz, Jacek; Rutkowski, Piotr; Arenberger, Petr; Quereux, Gaelle; Meniawy, Tarek M.; Ascierto, Paolo A.; Menzies, Alexander M.; Durani, Piyush; Lobo, Maurice; Campigotto, Federico; Gastman, Brian; Long, Georgina V.
errShare
errSave
Adjuvant nivolumab in resected stage IIB/C melanoma: primary results from the randomized, phase 3 CheckMate 76K trial
errNATURE MEDICINE
IF50
err2023-10-16
err53
errOAAI
errKirkwood, John; Del Vecchio, Michele; Weber, Jeffrey; Hoeller, Christoph; Grob, Jean-Jacques; Mohr, Peter; Loquai, Carmen; Dutriaux, Caroline; Chiarion-Sileni, Vanna; Mackiewicz, Jacek; Rutkowski, Piotr; Arenberger, Petr; Quereux, Gaelle; Meniawy, Tarek M.; Ascierto, Paolo A.; Menzies, Alexander M.; Durani, Piyush; Lobo, Maurice; Campigotto, Federico; Gastman, Brian; Long, Georgina V.
errShare
errSave
Pathologic response and exploratory analyses of neoadjuvant-adjuvant versus adjuvant pembrolizumab (PEM) for resectable stage IIIb-IV melanoma from SWOG S1801
errANNALS OF ONCOLOGY
IF65.4
err2023-10-01
err5
PREAI
errPatel, S.; Othus, M.; Wright, P.; Hyngstrom, J.; Lao, C. D.; Truong, T-G.; Chandra, S.; Kendra, K.; Devoe, C.; Hegde, A.; Mangla, A.; Lowe, M.; Buchbinder, E.; Kirkwood, J. M.; Sharon, E.; Korde, L.; Moon, J.; Sondak, V. K.; Ribas, A.; Prieto, V.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Dirk Schadendorf
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Jedd D. Wolchok
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Georgina V. Long
H-index: 169 · Papers: 1.8K
D
Drew M. Pardoll
H-index: 164 · Papers: 892
J
Jean‐Yves Blay
H-index: 158 · Papers: 2.4K
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