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Thomas Klein

apomedica pharmazeutische produkte gmbh

73H-index
730Paper Count
2.0WCitation Count
Published Papers 122
Publication Date
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Hepatic GCGR is required for the superior weight loss and metabolic effects of a structurally related analogue of the dual GCGR/GLP-1R agonist survodutide in mice
err2025-12-01
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PREAI
errLong, Fen; Challa, Tenagne D.; Efthymiou, Vissarion; Klug, Manuel; Klein, Thomas; Neubauer, Heike; Wolfrum, Christian; Horvath, Carla
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Pre-stroke weight loss by glucagon-like peptide 1 receptor and neuropeptide Y receptor Y2 activation improves post-stroke functional recovery in male diabetic mouse models
err2025-10-15
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errOAAI
errEllen Vercalsteren; Dimitra Karampatsi; Maria Neicu; Mihaela Oana Romanitan; Peter Haebel; Katherin Bleymehl; Thomas Nyström; Thomas Klein; Vladimer Darsalia; Cesare Patrone
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Empagliflozin reduces left ventricular mass increase and improves cardiomyocyte hypertrophy after 5/6 nephrectomy
err2025-08-28
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PREAI
errXin Chen; Christian T. Wohnhaas; Denis Delić; Nicolas Schommer; Daniel Duerschmied; Yaochen Cao; Zeyu Zhang; Christoph Reichetzeder; Mohamed M.S. Gaballa; Bernhard K. Krämer; Thomas Klein; Ben He; Linghong Shen; Berthold Hocher
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AAV Capsid Variant Screen for Diabetes Research: Building a Scalable Methodology for Modification of Human Islet Gene Expression
err2025-03-01
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PREAI
errGrepper, Susan; Jawurek, Sayro F.; Forschler, Felix; Rufer, Chantal; Nag, Madhu; Mir-Coll, Joan; Title, Alexandra C.; Lamla, Thorsten; Strobel, Benjamin; Klein, Thomas F.; Yesildag, Burcak
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The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
err2024-02-29
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errOAAI
errVercalsteren, Ellen; Karampatsi, Dimitra; Buizza, Carolina; Nystrom, Thomas; Klein, Thomas; Paul, Gesine; Patrone, Cesare; Darsalia, Vladimer
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Perspectives in weight control in diabetes - Survodutide
err2024-01-01
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PREAI
errKlein, Thomas; Augustin, Robert; Hennige, Anita M.
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Socio-economic inequalities in body mass index among preschool children: do sports programs in early childhood education and care centers make a difference?
err2023-06-22
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errOAAI
errMayer, Alena; Herr, Raphael M.; Klein, Thomas; Wiedemann, Eva; Diehl, Katharina; Hoffmann, Stephanie; Blume, Miriam; Jepsen, Dennis; Sundmacher, Leonie; Andreas, Marike; Schneider, Sven
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Renoprotective effects of empagliflozin are linked to activation of the tubuloglomerular feedback mechanism and blunting of the complement system
err2023-04-01
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errOAAI
errChen, Xin; Delic, Denis; Cao, Yaochen; Shen, Linghong; Shao, Qin; Zhang, Zheyu; Wu, Hongwei; Hasan, Ahmed A.; Reichetzeder, Christoph; Gaballa, Mohamed M. S.; Kraemer, Bernhard K.; Klein, Thomas; Yin, Lianghong; He, Ben; Morgera, Stanislao; Hocher, Berthold
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Linagliptin treatment is associated with altered cobalamin (VitB12) homeostasis in mice and humans
err2023-01-12
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errOAAI
errTammen, Harald; Koemhoff, Martin; Delic, Denis; Lund, Soren S.; Hocher, Berthold; Frankenreiter, Sandra; Hess, Ruediger; von Eynatten, Maximilian; Mark, Michael; Klein, Thomas
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Fibroblast Activation Protein Activates Macrophages and Promotes Parenchymal Liver Inflammation and Fibrosis
err2023-01-01
err49
errOAAI
errYang, Ai-Ting; Kim, Yong-Ook; Yan, Xu-Zhen; Abe, Hiroyuki; Aslam, Misbah; Park, Kyoung-Sook; Zhao, Xin-Yan; Jia, Ji-Dong; Klein, Thomas; You, Hong; Schuppan, Detlef
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Empagliflozin reduces kidney fibrosis and improves kidney function by alternative macrophage activation in rats with 5/6-nephrectomy
err2022-12-01
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errOAAI
errLu, Yong-Ping; Wu, Hong-Wei; Zhu, Ting; Li, Xi -Tong; Zuo, Jiao; Hasan, Ahmed A.; Reichetzeder, Christoph; Delic, Denis; Yard, Benito; Klein, Thomas; Kramer, Bernhard K.; Zhang, Ze-Yu; Wang, Xiao-Hua; Yin, Liang-Hong; Dai, Yong; Zheng, Zhi-Hua; Hocher, Berthold
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DPP-4 Inhibitor and Sulfonylurea Differentially Reverse Type 2 Diabetes-Induced Blood-Brain Barrier Leakage and Normalize Capillary Pericyte Coverage
err2022-11-30
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errOAAI
errElabi, Osama F.; Karampatsi, Dimitra; Vercalsteren, Ellen; Lietzau, Grazyna; Nystroem, Thomas; Klein, Thomas; Darsalia, Vladimer; Patrone, Cesare; Paul, Gesine
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Head-to-head comparison of two SGLT-2 inhibitors on AKI outcomes in a rat ischemia-reperfusion model
err2022-09-01
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errOAAI
errChu, Chang; Delic, Denis; Alber, Jana; Feger, Martina; Xiong, Yingquan; Luo, Ting; Hasan, Ahmed A.; Zeng, Shufei; Gaballa, Mohamed M. S.; Chen, Xin; Yin, Lianghong; Klein, Thomas; Elitok, Saban; Kraemer, Bernhard K.; Foeller, Michael; Hocher, Berthold
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Evaluation of the Effects of Harmine on β-cell Function and Proliferation in Standardized Human Islets Using 3D High-Content Confocal Imaging and Automated Analysis
err2022-07-04
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errTitle, Alexandra C.; Karsai, Maria; Mir-Coll, Joan; Grining, Oezlem Yavas; Rufer, Chantal; Sonntag, Sebastian; Forschler, Felix; Jawurek, Sayro; Klein, Thomas; Yesildag, Burcak
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Antifibrotic effects of low dose SGLT2 Inhibition with empagliflozin in comparison to Ang II receptor blockade with telmisartan in 5/6 nephrectomised rats on high salt diet
err2022-02-01
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errOAAI
errZeng, Shufei; Delic, Denis; Chu, Chang; Xiong, Yingquan; Luo, Ting; Chen, Xiaoyi; Gaballa, Mohamed M. S.; Xue, Yao; Chen, Xin; Cao, Yaochen; Hasan, Ahmed A.; Stadermann, Kai; Frankenreiter, Sandra; Yin, Lianghong; Kraemer, Bernhard K.; Klein, Thomas; Hocher, Berthold
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Mutations and variants of ONECUT1 in diabetes
err2021-10-18
err30
errOAAI
errPhilippi, Anne; Heller, Sandra; Costa, Ivan G.; Senee, Valerie; Breunig, Markus; Li, Zhijian; Kwon, Gino; Russell, Ronan; Illing, Anett; Lin, Qiong; Hohwieler, Meike; Degavre, Anne; Zalloua, Pierre; Liebau, Stefan; Schuster, Michael; Krumm, Johannes; Zhang, Xi; Geusz, Ryan; Benthuysen, Jacqueline R.; Wang, Allen; Chiou, Joshua; Gaulton, Kyle; Neubauer, Heike; Simon, Eric; Klein, Thomas; Wagner, Martin; Nair, Gopika; Besse, Celine; Dandine-Roulland, Claire; Olaso, Robert; Deleuze, Jean-Francois; Kuster, Bernhard; Hebrok, Matthias; Seufferlein, Thomas; Sander, Maike; Boehm, Bernhard O.; Oswald, Franz; Nicolino, Marc; Julier, Cecile; Kleger, Alexander
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GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk
err2021-07-05
err12
errOAAI
errHe, Wei; Rebello, Osmond D.; Henne, Antonia; Nikolka, Fabian; Klein, Thomas; Maedler, Kathrin
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