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Microfluidic vessel-on-chip platform for investigation of cellular defects in venous malformations and responses to various shear stress and flow conditions Ansarizadeh, Mohammadhassan; Nguyen, Hoang-Tuan; Lazovic, Bojana; Kettunen, Jere; De Silva, Laknee; Sivakumar, Ragul; Junttila, Pauliina; Rissanen, Siiri-Liisa; Hicks, Ryan; Singh, Prateek; Eklund, Lauri Share Save
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Human iPSC and CRISPR targeted gene knock-in strategy for studying the somatic TIE2L914F mutation in endothelial cells (May, 10.1007/s10456-024-09925-9, 2024) Lazovic, Bojana; Nguyen, Hoang-Tuan; Ansarizadeh, Mohammadhassan; Wigge, Leif; Kohl, Franziska; Li, Songyuan; Carracedo, Miguel; Kettunen, Jere; Krimpenfort, Luc; Elgendy, Ramy; Richter, Kati; De Silva, Laknee; Bilican, Bilada; Singh, Prateek; Saxena, Pratik; Jakobsson, Lars; Hong, Xuechong; Eklund, Lauri; Hicks, Ryan Share Save
Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema Brouillard, Pascal; Murtomaki, Aino; Leppanen, Veli-Matti; Hyytiainen, Marko; Mestre, Sandrine; Potier, Lucas; Boon, Laurence M.; Revencu, Nicole; Greene, Arin; Anisimov, Andrey; Salo, Miia H.; Hinttala, Reetta; Eklund, Lauri; Quere, Isabelle; Alitalo, Kari; Vikkula, Miikka Share Save
Contribution of VEGF-B-Induced Endocardial Endothelial Cell Lineage in Physiological Versus Pathological Cardiac Hypertrophy Sultan, Ibrahim; Ramste, Markus; Peletier, Pim; Hemanthakumar, Karthik Amudhala; Ramanujam, Deepak; Tirronen, Annakaisa; von Wright, Ylva; Antila, Salli; Saharinen, Pipsa; Eklund, Lauri; Mervaala, Eero; Yla-Herttuala, Seppo; Engelhardt, Stefan; Kivelae, Riikka; Alitalo, Kari Share Save
Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer's disease-related amyloid pathology Antila, Salli; Chilov, Dmitri; Nurmi, Harri; Li, Zhilin; Nasi, Anni; Gotkiewicz, Maria; Sitnikova, Valeriia; Jaentti, Henna; Acosta, Natalia; Koivisto, Hennariikka; Ray, Jonathan; Keuters, Meike Hedwig; Sultan, Ibrahim; Scoyni, Flavia; Trevisan, Davide; Wojciechowski, Sara; Kaakinen, Mika; Dvorakova, Lenka; Singh, Abhishek; Jukkola, Jari; Korvenlaita, Nea; Eklund, Lauri; Koistinaho, Jari; Karaman, Sinem; Malm, Tarja; Tanila, Heikki; Alitalo, Kari Share Save
Synchronous functional magnetic resonance eye imaging, video ophthalmoscopy, and eye surface imaging reveal the human brain and eye pulsation mechanisms Ebrahimi, Seyed-Mohsen; Tuunanen, Johanna; Saarela, Ville; Honkamo, Marja; Huotari, Niko; Raitamaa, Lauri; Korhonen, Vesa; Helakari, Heta; Jarvela, Matti; Kaakinen, Mika; Eklund, Lauri; Kiviniemi, Vesa Share Save
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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika; Giese, Wolfgang; Baumann, Elisabeth; Szymborska, Anna; Rosa, Andre; Nordling, Sofia; Schimmel, Lilian; Akmeric, Emir Bora; Pena, Andreia; Nwadozi, Emmanuel; Jamalpour, Maria; Holstein, Katrin; Sainz-Jaspeado, Miguel; Bernabeu, Miguel O.; Welsh, Michael; Gordon, Emma; Franco, Claudio A.; Vestweber, Dietmar; Eklund, Lauri; Gerhardt, Holger; Claesson-Welsh, Lena Share Save
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Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression Korhonen, Emilia A.; Murtomaki, Aino; Jha, Sawan Kumar; Anisimov, Andrey; Pink, Anne; Zhang, Yan; Stritt, Simon; Liaqat, Inam; Stanczuk, Lukas; Alderfer, Laura; Sun, Zhiliang; Kapiainen, Emmi; Singh, Abhishek; Sultan, Ibrahim; Lantta, Anni; Leppanen, Veli-Matti; Eklund, Lauri; He, Yulong; Augustin, Hellmut G.; Vaahtomeri, Kari; Saharinen, Pipsa; Makinen, Taija; Alitalo, Kari Share Save
Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner Richards, Mark; Nwadozi, Emmanuel; Pal, Sagnik; Martinsson, Pernilla; Kaakinen, Mika; Gloger, Marleen; Sjoberg, Elin; Koltowska, Katarzyna; Betsholtz, Christer; Eklund, Lauri; Nordling, Sofia; Claesson-Welsh, Lena Share Save
PHD2 deletion in endothelial or arterial smooth muscle cells reveals vascular cell type-specific responses in pulmonary hypertension and fibrosis Elamaa, Harri; Kaakinen, Mika; Natynki, Marjut; Szabo, Zoltan; Ronkainen, Veli-Pekka; Aijala, Ville; Maki, Joni M.; Kerkela, Risto; Myllyharju, Johanna; Eklund, Lauri Share Save
Computer extracted gland features from H&E predicts prostate cancer recurrence comparably to a genomic companion diagnostic test: a large multi-site study Leo, Patrick; Janowczyk, Andrew; Elliott, Robin; Janaki, Nafiseh; Bera, Kaustav; Shiradkar, Rakesh; Farre, Xavier; Fu, Pingfu; El-Fahmawi, Ayah; Shahait, Mohammed; Kim, Jessica; Lee, David; Yamoah, Kosj; Rebbeck, Timothy R.; Khani, Francesca; Robinson, Brian D.; Eklund, Lauri; Jambor, Ivan; Merisaari, Harri; Ettala, Otto; Taimen, Pekka; Aronen, Hannu J.; Bostrom, Peter J.; Tewari, Ashutosh; Magi-Galluzzi, Cristina; Klein, Eric; Purysko, Andrei; NC Shih, Natalie; Feldman, Michael; Gupta, Sanjay; Lal, Priti; Madabhushi, Anant Share Save
The Amino-Terminal Oligomerization Domain of Angiopoietin-2 Affects Vascular Remodeling, Mammary for Gland Tumor Growth, and Lung Metastasis in Mice Kapiainen, Emmi; Kihlstrom, Minna K.; Pietila, Riikka; Kaakinen, Mika; Ronkainen, Veli-Pekka; Tu, Hongmin; Heikkinen, Anne; Devarajan, Raman; Miinalainen, Ilkka; Laitakari, Anna; Ansarizadeh, Mohammadhassan; Zhang, Qin; Wei, Gong-Hong; Ruddock, Lloyd; Pihlajaniemi, Taina; Elamaa, Harri; Eklund, Lauri Share Save
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