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Patrizia Agostinis

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H-index:99
Citation Count:6.1万
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An iron logic unites bacterial and cancer persister cells

铁逻辑统一了细菌和癌症持久性细胞

Nature Reviews Molecular Cell Biology
IF90.2
2026-08-110
PRE
Raphaël Rodriguez; Patrizia Agostinis
Autophagy maintains high endothelial venule identity and function during inflammation

自噬在炎症期间维持高内皮静脉的表型和功能

Immunity
IF26.3
2026-07-170
OAAI
Kathryn A. Jacobs; Yichao Hua; Apostolos Panagiotis Nikolakopoulos; Swati Gupta; Gerlanda Vella; Ana Filipa Domingues Laranjeiro; Julie Bonnereau; Mélanie Guyot; Maria Livia Sassano; Larissa Mourao; Feyza Cansiz; Gabriele Allies; Nicolas Van Baren; Sophie Lucas; Hiroto Kawashima; Wiebke Sondermann; Florian Rambow; Alpaslan Tasdogan; Colinda Scheele; Patrizia Agostinis
Stress granules shape ferroptosis in cancer

应激小体塑造癌症中的铁死亡

Nature Cell Biology
IF19.1
2026-05-220
PRE
Maria Livia Sassano; Patrizia Agostinis
ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbances

ADA2缺陷细胞表现出细胞死亡和代谢紊乱水平升高

Cell Death Discovery
IF7
2026-03-230
PRE
Ehlers, Lisa; Wouters, Marjon; Pillay, Bethany; Delafontaine, Selket; Bucciol, Giorgia; Baggio, Marco; Dzhus, Mariia; Hombrouck, Anneleen; Damerau, Alexandra; De Somer, Lien; Schrijvers, Rik; Vanderschueren, Steven; Jacquemyn, Maarten; Kallinich, Tilmann; Daelemans, Dirk; Ghesquiere, Bart; Agostinis, Patrizia; Moens, Leen; Meyts, Isabelle
AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis

AMP激活蛋白激酶驱动的脂滴动力学调控黑素瘤对多不饱和脂肪酸和铁诱导的铁死亡敏感性

Nature Communications
IF15.7
2025-12-170
OAAI
Sahar Motamedi; Nina Ravoet; Jonas Dehairs; Frank Vanderhoydonc; Abril Escamilla-Ayala; Malgorzata A. Sliwinska; Shuncong Wang; Jakub Idkowiak; Stefaan Soenen; Patrizia Agostinis; Jean-Christophe Marine; Johannes V. Swinnen
BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states

BDH2驱动的溶酶体到线粒体的铁转移塑造了黑色素瘤细胞状态的铁死亡易感性。

Nature Metabolism
IF20.8
2025-09-160
OAAI
Francesca Rizzollo; Abril Escamilla-Ayala; Nicola Fattorelli; Natalia Barbara Lysiak; Sanket More; Pablo Hernández Varas; Lucia Barazzuol; Chris Van den Haute; Joris Van Asselberghs; David Nittner; Jonathan Coene; Vivek Venkataramani; Bernhard Michalke; Christine Gaillet; Tatiana Cañeque; Irwin Davidson; Steven H. L. Verhelst; Peter Vangheluwe; Tito Calì; Jean-Christophe Marine; Raphaël Rodriguez; Julie Bonnereau; Patrizia Agostinis
Author Correction: Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis

作者更正: 内质网-线粒体接触是磷脂过氧化驱动铁死亡的主要热点

Nature Cell Biology
IF19.1
2025-08-040
OAAI
Maria Livia Sassano; Yulia Y. Tyurina; Antigoni Diokmetzidou; Ellen Vervoort; Vladimir A. Tyurin; Sanket More; Rita La Rovere; Francesca Giordano; Geert Bultynck; Benjamin Pavie; Johan V. Swinnen; Hülya Bayir; Valerian E. Kagan; Luca Scorrano; Patrizia Agostinis
Inhibition of lysosomal degradation increases expression of mutant ADA2 in DADA2 monocytes

溶酶体降解的抑制增加了DADA2单核细胞中突变型ADA2的表达

Journal of Allergy and Clinical Immunology
IF11.2
2025-06-200
OAAI
Lisa Ehlers; Marjon Wouters; Bethany Pillay; Selket Delafontaine; Mariia Dzhus; Marco Baggio; Tim Niehues; Gregor Dückers; Lieve Sevenants; Kristina Casteels; Lien De Somer; Rik Schrijvers; Steven Vanderschueren; Maarten Jacquemyn; Dirk Daelemans; Anneleen Hombrouck; Eugene P. Chambers; Thomas Tousseyn; Giorgia Bucciol; Patrizia Agostinis; Leen Moens; Isabelle Meyts
Endoplasmic reticulum–mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosis

内质网-线粒体接触是磷脂过氧化驱动铁死亡的主要热点

Nature Cell Biology
IF19.1
2025-06-130
OA
Maria Livia Sassano; Yulia Y. Tyurina; Antigoni Diometzidou; Ellen Vervoort; Vladimir A. Tyurin; Sanket More; Rita La Rovere; Francesca Giordano; Geert Bultynck; Benjamin Pavie; Johan V. Swinnen; Hülya Bayir; Valerian E. Kagan; Luca Scorrano; Patrizia Agostinis
NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis (vol 24, pg 269, 2019)

Nf-κb有助于Smac模拟物赋予的保护作用免受衣霉素诱导的细胞凋亡 (第24卷，269页，2019)

APOPTOSIS
IF8.1
2025-03-010
PRE
Abhari, Behnaz Ahangarian; Mccarthy, Nicole; Agostinis, Patrizia; Fulda, Simone
STIMulating IRE1: How store-operated Ca2+entry intersects with ER proteostasis

刺激IRE1: 商店经营的Ca2入口如何与ER蛋白平衡相交

CELL CALCIUM
IF4
2025-01-010
PRE
Sassano, Maria Livia; Van Gorp, Robbe; Bultynck, Geert; Agostinis, Patrizia
Secreted Apoe rewires melanoma cell state vulnerability to ferroptosis

分泌的Apoe重新连接黑色素瘤细胞状态对铁死亡的脆弱性

SCIENCE ADVANCES
IF12.5
2024-10-181
OAAI
More, Sanket; Bonnereau, Julie; Wouters, David; Spotbeen, Xander; Karras, Panagiotis; Rizzollo, Francesca; Killian, Theo; Venken, Tom; Naulaerts, Stefan; Vervoort, Ellen; Ganne, Maarten; Nittner, David; Verhoeven, Jelle; Bechter, Oliver; Bosisio, Francesca; Lambrechts, Diether; Sifrim, Alejandro; Stockwell, Brent R.; Swinnen, Johannes V.; Marine, Jean Christophe; Agostinis, Patrizia
Missense variants in CMS22 patients reveal that PREPL has both enzymatic and nonenzymatic functions

CMS22患者的错义变异表明PREPL具有酶和非酶功能

JCI INSIGHT
IF6.1
2024-09-100
OA
Monnens, Yenthe; Theodoropoulou, Anastasia; Rosier, Karen; Bhalla, Kritika; Mahy, Alexia; Vanhoutte, Roeland; Meulemans, Sandra; Cavani, Edoardo; Antanasijevic, Aleksandar; Lemmens, Irma; Lee, Jennifer A.; Spellicy, Catherine J.; Schroer, Richard J.; Maselli, Ricardo A.; Laverty, Chamindra G.; Agostinis, Patrizia; Pagliarini, David J.; Verhelst, Steven; Marcaida, Maria J.; Rochtus, Anne; Dal Peraro, Matteo; Creemers, John W. M.
A deep phenotyping study in mouse and iPSC models to understand the role of oligodendroglia in optic neuropathy in Wolfram syndrome
ACTA NEUROPATHOLOGICA COMMUNICATIONS
IF5.7
2024-08-280
OAAI
Ahuja, K.; Vandenabeele, M.; Nami, F.; Lefevere, E.; Van Hoecke, J.; Bergmans, S.; Claes, M.; Vervliet, T.; Neyrinck, K.; Burg, T.; De Herdt, D.; Bhaskar, P.; Zhu, Y.; Looser, Z. J.; Loncke, J.; Gsell, W.; Plaas, M.; Agostinis, P.; Swinnen, J. V.; van den Bosch, L.; Bultynck, G.; Saab, A. S.; Wolfs, E.; Chai, Y. C.; Himmelreich, U.; Verfaillie, C.; Moons, L.; De Groef, L.
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs (vol 147, 6, 2024)

来自hipsc的突变FUS少突胶质祖细胞中MAM完整性的破坏 (147卷，6，2024)

ACTA NEUROPATHOLOGICA
IF9.3
2024-06-130
OAAI
Zhu, Yingli; Burg, Thibaut; Neyrinck, Katrien; Vervliet, Tim; Nami, Fatemeharefeh; Vervoort, Ellen; Ahuja, Karan; Sassano, Maria Livia; Chai, Yoke Chin; Tharkeshwar, Arun Kumar; De Smedt, Jonathan; Hu, Haibo; Bultynck, Geert; Agostinis, Patrizia; Swinnen, Johannes V.; van den Bosch, Ludo; da Costa, Rodrigo Furtado Madeiro; Verfaillie, Catherine
Antioxidant network-based signatures cluster glioblastoma into distinct redox-resistant phenotypes

基于抗氧化剂网络的特征将胶质母细胞瘤聚类为不同的氧化还原抗性表型

FRONTIERS IN IMMUNOLOGY
IF5.9
2024-04-180
OAAI
Yang, Yihan; More, Sanket; De Smet, Frederik; De Vleeschouwer, Steven; Agostinis, Patrizia
An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

促进T细胞从淋巴结流出的自噬程序控制对免疫检查点阻断的反应

CELL REPORTS
IF6.9
2024-04-011
OA
Houbaert, Diede; Nikolakopoulos, Apostolos Panagiotis; Jacobs, Kathryn A.; Mece, Odeta; Roels, Jana; Shankar, Gautam; Agrawal, Madhur; More, Sanket; Ganne, Maarten; Rillaerts, Kristine; Boon, Louis; Swoboda, Magdalena; Nobis, Max; Mourao, Larissa; Bosisio, Francesca; Vandamme, Niels; Bergers, Gabriele; Scheele, Colinda L. G. J.; Agostinis, Patrizia
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs

来自hipsc的突变FUS少突胶质祖细胞中MAM完整性的破坏

ACTA NEUROPATHOLOGICA
IF9.3
2024-01-033
OAAI
Zhu, Yingli; Burg, Thibaut; Neyrinck, Katrien; Vervliet, Tim; Nami, Fatemeharefeh; Vervoort, Ellen; Ahuja, Karan; Sassano, Maria Livia; Chai, Yoke Chin; Tharkeshwar, Arun Kumar; De Smedt, Jonathan; Hu, Haibo; Bultynck, Geert; Agostinis, Patrizia; Swinnen, Johannes V.; Van den Bosch, Ludo; da Costa, Rodrigo Furtado Madeiro; Verfaillie, Catherine
Decoding immunogenic cell death from a dendritic cell perspective

从树突状细胞的角度解码免疫原性细胞死亡

IMMUNOLOGICAL REVIEWS
IF8.3
2023-12-138
OAAI
Janssens, Sophie; Rennen, Sofie; Agostinis, Patrizia
Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma

肿瘤内皮细胞自噬是黑色素瘤中关键的血管免疫检查点

EMBO MOLECULAR MEDICINE
IF8.3
2023-11-277
OAAI
Verhoeven, Jelle; Jacobs, Kathryn A.; Rizzollo, Francesca; Lodi, Francesca; Hua, Yichao; Pozniak, Joanna; Srinivasan, Adhithya Narayanan; Houbaert, Diede; Shankar, Gautam; More, Sanket; Schaaf, Marco B.; Lakic, Nikolina Dubroja; Ganne, Maarten; Lamote, Jochen; Van Weyenbergh, Johan; Boon, Louis; Bechter, Oliver; Bosisio, Francesca; Uchiyama, Yasuo; Bertrand, Mathieu J. M.; Marine, Jean Christophe; Lambrechts, Diether; Bergers, Gabriele; Agrawal, Madhur; Agostinis, Patrizia

Research Directions

The data has not been retrieved yet.
A
Abhishek D. Garg
H-index:70Papers:334Citations:3.8万
P
Peter Vandenabeele
H-index:154Papers:670Citations:10.7万
J
Johannes V. Swinnen
H-index:76Papers:608Citations:2.0万
M
Maria Livia Sassano
H-index:12Papers:23Citations:2,009
D
Dmitri V. Krysko
H-index:63Papers:173Citations:2.1万
G
Geert Bultynck
H-index:76Papers:357Citations:2.9万
M
Marjan Garmyn
H-index:37Papers:163Citations:8,376
H
Hannelore Maes
H-index:19Papers:56Citations:7,816
S
Sanket More
H-index:10Papers:19Citations:1,705
G
Guido Kroemer
H-index:283Papers:2,326Citations:36.9万