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J

John Rex

f2g inc.

101H-index
544Paper Count
4.4WCitation Count
Published Papers 79
Publication Date
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Paradoxical worsening on olorofim in patients undergoing treatment for invasive fungal diseases
errClinical Microbiology and Infection
IF8.5
err2025-12-29
err0
PREAI
errGeorge R. Thompson; Anke H.W. Bruns; Jannik Helweg-Larsen; Philipp Koehler; Jeffrey D. Jenks; Bennett Penn; Martin Hoenigl; Johan Maertens; Andrej Spec; Thomas J. Walsh; Mark Bresnik; John H. Rex
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errSave
Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study
errThe Lancet Infectious Diseases
IF0
err2025-06-18
err0
PREAI
errJohan A Maertens; George R Thompson; Andrej Spec; Fariba M Donovan; Sarah P Hammond; Anke H W Bruns; Galia Rahav; Shmuel Shoham; Royce Johnson; Bart Rijnders; Joanna Schaenman; Martin Hoenigl; C Orla Morrissey; Sanjay R Mehta; Christopher H Heath; Philipp Koehler; David L Paterson; Monica A Slavin; Jesus Fortún; M Hong Nguyen; Thomas F Patterson; Olga Uspenskaya; Frank L Van de Veerdonk; Paul E Verweij; Mickael Aoun; Aspasia Georgala; Barbara D Alexander; Methee Chayakulkeeree; Varun Mehra; Marisa H Miceli; Monica K Sikka; Amparo Solé; Thomas J Walsh; Jose Maria Aguado; Steven M Holland; Mohamed Moussa; Riina Rautemaa-Richardson; Rohit Bazaz; Stefan Schwartz; Stephen R Walsh; Markus Plate; Dana Yehudai-Ofir; Roger J Brüggemann; Oliver A Cornely; Luis Ostrosky-Zeichner; Jose A Vazquez; P Lewis White; Karen Cornelissen; Geoffrey G Ross; Lesley Fitton; Aaron Dane; Daniela Zinzi; John H Rex; Sharon C-A Chen
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Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-08-07
err3
errOAAI
errGigante, Valeria; Alm, Richard A.; Melchiorri, Daniela; Rocke, Tamarie; Arias, Cesar A.; Czaplewski, Lloyd; Fernandes, Prabhavathi; Franceschi, Francois; Harbarth, Stephan; Kozlov, Roman; Lienhardt, Christian; Ohmagari, Norio; Ogilvie, Lesley A.; Paul, Mical; Rex, John H.; Silver, Lynn L.; Spigelman, Melvin; Sati, Hatim; Cameron, Alexandra M.
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Food and Drug Administration Public Workshop Summary-Development Considerations of Antifungal Drugs to Address Unmet Medical Need
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2023-04-06
err4
errOAAI
errYasinskaya, Yuliya; Bala, Shukal; Waack, Ursula; Dixon, Cheryl; Higgins, Karen; Moore, Jason N.; Jjingo, Caroline J.; O'Shaughnessy, Elizabeth; Colangelo, Philip; Botgros, Radu; Nambiar, Sumathi; Angulo, David; Dane, Aaron; Chiller, Tom; Hodges, Michael R.; Sandison, Taylor; Hope, William; Walsh, Thomas J.; Pappas, Peter; Katragkou, Aspasia; Kovanda, Laura; Rex, John H.; Marr, Kieren A.; Ostrosky-Zeichner, Luis; Sekine, Shohko; Deshpande, Monika; Shukla, Sunita J.; Farley, John
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errSave
Global Pull Incentives for Better Antibacterials: The UK Leads the Way
errAPPLIED HEALTH ECONOMICS AND HEALTH POLICY
IF3.3
err2023-02-11
err6
errOAAI
errOutterson, Kevin; Rex, John H.
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errSave
The Value of the Information That Can Be Generated: Optimizing Study Design to Enable the Study of Treatments Addressing an Unmet Need for Rare Pathogens
errOPEN FORUM INFECTIOUS DISEASES
IF3.8
err2022-05-27
err0
errOAAI
errDane, Aaron; Rex, John H.; Newell, Paul; Stallard, Nigel
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errSave
Reply to Kaye and Belley, Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too! REPLY
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2022-04-19
err0
errOAAI
errButler, Mark S.; Gigante, Valeria; Sati, Hatim; Paulin, Sarah; Al-Sulaiman, Laila; Rex, John H.; Fernandes, Prabhavathi; Arias, Cesar A.; Paul, Mical; Thwaites, Guy E.; Czaplewski, Lloyd; Alm, Richard A.; Lienhardt, Christian; Spigelman, Melvin; Silver, Lynn L.; Ohmagari, Norio; Kozlov, Roman; Harbarth, Stephan; Beyer, Peter
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errSave
Antimicrobial Resistance: Is Health Technology Assessment Part of the Solution or Part of the Problem?
errVALUE IN HEALTH
IF6
err2021-12-01
err22
errOAAI
errColson, Abigail R.; Morton, Alec; Ardal, Christine; Chalkidou, Kalipso; Davies, Sally C.; Garrison, Louis P.; Jit, Mark; Laxminarayan, Ramanan; Megiddo, Itamar; Morel, Chantal; Nonvignon, Justice; Outterson, Kevin; Rex, John H.; Sarker, Abdur Razzaque; Sculpher, Mark; Woods, Beth; Xiao, Yue
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errSave
FDA Public Workshop Summary-Coccidioidomycosis (Valley Fever): Considerations for Development of Antifungal Drugs
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2021-10-15
err9
PREAI
errO'Shaughnessy, Elizabeth; Yasinskaya, Yuliya; Dixon, Cheryl; Higgins, Karen; Moore, Jason; Reynolds, Kellie; Ampel, Neil M.; Angulo, David; Blair, Janis E.; Catanzaro, Antonino; Galgiani, John N.; Garvey, Edward; Johnson, Royce; Larwood, David J.; Lewis, Gareth; Purdie, Rob; Rex, John H.; Shubitz, Lisa F.; Stevens, David A.; Page, Stephen J.; Shukla, Sunita J.; Farley, John J.; Nambiar, Sumathi
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errSave
In Vivo Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2021-09-17
err28
errOAAI
errSeyedmousavi, S.; Chang, Y. C.; Youn, J. H.; Law, D.; Birch, M.; Rex, J. H.; Kwon-Chung, K. J.
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errSave
When to change treatment of acute invasive aspergillosis: an expert viewpoint
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2021-09-11
err19
errOAAI
errSlavin, Monica A.; Chen, Yee-Chun; Cordonnier, Catherine; Cornely, Oliver A.; Cuenca-Estrella, Manuel; Donnelly, J. Peter; Groll, Andreas H.; Lortholary, Olivier; Marty, Francisco M.; Nucci, Marcio; Rex, John H.; Rijnders, Bart J. A.; Thompson, George R.; Verweij, Paul E.; White, P. Lewis; Hargreaves, Ruth; Harvey, Emma; Maertens, Johan A.
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errSave
Patient Access in 14 High-Income Countries to New Antibacterials Approved by the US Food and Drug Administration, European Medicines Agency, Japanese Pharmaceuticals and Medical Devices Agency, or Health Canada, 2010-2020
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2021-07-12
err36
errOAAI
errOutterson, Kevin; Orubu, Ebiowei S. F.; Rex, John; Ardal, Christine; Zaman, Muhammad H.
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errSave
Antibiotic Development Incentives That Reflect Societal Value of Antibiotics
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2021-01-30
err0
PREAI
errBoucher, Helen W.; File, Thomas M.; Fowler, Vance G.; Jezek, Amanda; Rex, John H.; Outterson, Kevin
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errSave
Antibacterial R&D at a Crossroads: We've Pushed as Hard as We Can... Now We Need to Start Pulling! COMMENT
errCLINICAL INFECTIOUS DISEASES
IF7.3
err2020-06-25
err12
PREAI
errRex, John H.; Outterson, Kevin
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errSave
Evaluating for-profit public benefit corporations as an additional structure for antibiotic development and commercialization
errTRANSLATIONAL RESEARCH
IF5.9
err2020-06-01
err29
errOAAI
errOutterson, Kevin; Rex, John H.
errShare
errSave
Critical analysis of antibacterial agents in clinical development
errNATURE REVIEWS MICROBIOLOGY
IF103.3
err2020-03-09
err243
errOAAI
errTheuretzbacher, Ursula; Bush, Karen; Harbarth, Stephan; Paul, Mical; Rex, John H.; Tacconelli, Evelina; Thwaites, Guy E.
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errSave
Antibiotic development - economic, regulatory and societal challenges
errNATURE REVIEWS MICROBIOLOGY
IF103.3
err2019-11-19
err260
errOAAI
errArdal, Christine; Balasegaram, Manica; Laxminarayan, Ramanan; McAdams, David; Outterson, Kevin; Rex, John H.; Sumpradit, Nithima
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errSave
Designing development programs for non-traditional antibacterial agents
errNATURE COMMUNICATIONS
IF15.7
err2019-07-31
err54
errOAAI
errRex, John H.; Lynch, Holly Fernandez; Cohen, I. Glenn; Darrow, Jonathan J.; Outterson, Kevin
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errSave
Pharmacokinetic-Pharmacodynamic Evaluation of Ertapenem for Patients with Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2019-06-01
err8
errOAAI
errBader, J. C.; Lakota, E. A.; Dale, G. E.; Sader, H. S.; Rex, J. H.; Ambrose, P. G.; Bhavnani, S. M.
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errSave
Efficacy of Olorofim (F901318) against Aspergillus fumigatus, A. nidulans, and A. tanneri in Murine Models of Profound Neutropenia and Chronic Granulomatous Disease
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2019-06-01
err42
errOAAI
errSeyedmousavi, S.; Chang, Y. C.; Law, D.; Birch, M.; Rex, J. H.; Kwon-Chung, K. J.
errShare
errSave

Research Directions

No research directions
Co-authors
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