Brooke M. Emerling - Publications, H-index & Citations

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Brooke M. Emerling

Sanford Burnham Prebys Medical Discovery Institute

23H-index

78Paper Count

5.4KCitation Count

Published Papers 42

Publication Date

Sulfotransferase signaling sustains fibroblast identity and antagonizes therapeutic cardiac reprogramming

Nature Communications

IF15.7

2026-07-17

OAAI

Michaela R. Romero; Sean Murphy; Yu-Ling Chang; Aashna Lamba; Sara Ancel; Alicia Llorente; James Marchant; Chun-Teng Huang; Caroline Kumsta; Peter Andersen; Sanjeev Ranade; Ahmed I. Mahmoud; Chulan Kwon; Hudson H. Freeze; Peter D. Adams; Alessandra Sacco; Mark J. Ranek; Brooke M. Emerling; Yu Xin Wang; Alexandre R. Colas

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Noncanonical PI(4; 5)P2 coordinates lysosome positioning through cholesterol trafficking

Science Advances

IF12.5

2026-05-22

OAAI

Ryan M. Loughran; Gurpreet K. Arora; Jiachen Sun; Alicia Llorente; Sophia Crabtree; Cynthia Y. Zhang; Kyanh Ly; Ren-Li Huynh; Wonhwa Cho; Brooke M. Emerling

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A proximity-labeling map of PI5P4K phosphoinositide kinases interaction networks

Journal of Biological Chemistry

IF3.9

2026-04-25

OAAI

Alicia Llorente; Gurpreet K. Arora; Ryan M. Loughran; Rabi Murad; Svetlana Maurya; Sophia Crabtree; Benji Portillo; Pratima Chapagain; Hundaol Huluka; Scott Eron; Krista Goodman; Guosen Ye; Raymond D. Blind; Brooke M. Emerling

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PI5P4Kα promotes glucose and iron acquisition to support metabolic fitness in pancreatic cancer

Cell Reports

IF6.9

2025-08-29

PREAI

Gurpreet K. Arora; Ryan M. Loughran; Kyanh Ly; Cheska Marie Galapate; Alicia Llorente; Taylor R. Anderson; Cynthia Y. Zhang; Shea F. Grenier; Li Ling; Sophia Crabtree; Guillem Lambies; Chantal Pauli; David A. Scott; Yoav Altman; Benji Portillo; Rabi Murad; Cosimo Commisso; Brooke M. Emerling

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Loss of PI5P4Kα Slows the Progression of a Pten Mutant Basal Cell Model of Prostate Cancer

MOLECULAR CANCER RESEARCH

IF4.7

2024-10-09

OAAI

Triscott, Joanna; Lehner, Marika; Benjak, Andrej; Reist, Matthias; Emerling, Brooke M.; Ng, Charlotte K. Y.; de Brot, Simone; Rubin, Mark A.

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PI5P4Kα regulates cell fitness through iron homeostasis in pancreatic cancer

CANCER RESEARCH

IF16.6

2024-09-15

PREAI

Arora, Gurpreet Kaur; Loughran, Ryan; Ly, Kyanh; Galapate, Cheska Marie; Llorente, Alicia; Anderson, Taylor R.; Pauli, Chantal; Scott, David A.; Altman, Yoav; Commisso, Cosimo; Emerling, Brooke M.

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Hippo and PI5P4K signaling intersect to control the transcriptional activation of YAP

SCIENCE SIGNALING

IF6.6

2024-05-28

OAAI

Palamiuc, Lavinia; Johnson, Jared L.; Haratipour, Zeinab; Loughran, Ryan M.; Choi, Woong Jae; Arora, Gurpreet K.; Tieu, Vivian; Ly, Kyanh; Llorente, Alicia; Crabtree, Sophia; Wong, Jenny C. Y.; Ravi, Archna; Wiederhold, Thorsten; Murad, Rabi; Blind, Raymond D.; Emerling, Brooke M.

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PIKfyve as a potential therapeutic target in pancreatic cancer

CANCER RESEARCH

IF16.6

2024-01-16

PREAI

Grenier, Shea; Galapate, Cheska; Zhang, Yijuan; Arora, Gurpreet; Olson, Steven; Emerling, Brooke; Commisso, Cosimo

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Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

254

OAAI

Emerling, BM; Platanias, LC; Black, E; Nebreda, AR; Davis, RJ; Chandel, NS

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PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition

SCIENCE ADVANCES

IF12.5

2023-02-03

OAAI

Triscott, Joanna; Reist, Matthias; King, Lukas; Moselle, Francielle C.; Lehner, Marika; Gallon, John; Ravi, Archna; Arora, Gurpreet K.; de Brot, Simone; Lundquist, Mark; Gallart-Ayala, Hector; Ivanisevic, Julijana; Piscuoglio, Salvatore; Cantley, Lewis C.; Emerling, Brooke M.; Rubin, Mark A.

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Beyond PI3Ks: targeting phosphoinositide kinases in disease

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2022-11-14

OAAI

Burke, John E.; Triscott, Joanna; Emerling, Brooke M.; Hammond, Gerald R., V

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Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi

CELL REPORTS METHODS

IF4.5

2022-07-01

OAAI

Amen, Alexandra M.; Loughran, Ryan M.; Huang, Chun-Hao; Lew, Rachel J.; Ravi, Archna; Guan, Yuanzhe; Schatoff, Emma M.; Dow, Lukas E.; Emerling, Brooke M.; Fellmann, Christof

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Expanding role of PI5P4Ks in cancer: A promising druggable target

FEBS LETTERS

IF3

2021-12-07

OAAI

Arora, Gurpreet K.; Palamiuc, Lavinia; Emerling, Brooke M.

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A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients

MOLECULAR CANCER RESEARCH

IF4.7

2021-11-02

OAAI

Pauli, Chantal; De Boni, Lamberto; Pauwels, Jonathan E.; Chen, Yanjiang; Planas-Paz, Lara; Shaw, Reid; Emerling, Brooke M.; Grandori, Carla; Hopkins, Benjamin D.; Rubin, Mark A.

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PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay

DEVELOPMENTAL CELL

IF8.7

2021-06-01

OAAI

Ravi, Archna; Palamiuc, Lavinia; Loughran, Ryan M.; Triscott, Joanna; Arora, Gurpreet K.; Kumar, Avi; Tieu, Vivian; Pauli, Chantal; Reist, Matthias; Lew, Rachel J.; Houlihan, Shauna L.; Fellmann, Christof; Metallo, Christian; Rubin, Mark A.; Emerling, Brooke M.

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ORP5 regulates PI(4)P on the lipid droplet: Novel players on the monolayer

JOURNAL OF CELL BIOLOGY

IF6.4

2019-12-23

OAAI

Renne, Mike F.; Emerling, Brooke M.

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Phosphoinositides in autophagy: current roles and future insights

FEBS JOURNAL

IF4.2

2019-11-21

OAAI

Palamiuc, Lavinia; Ravi, Archna; Emerling, Brooke M.

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Towards understanding noncanonical phosphatidylinositol kinases in the maintenance of prostate metabolism.

CANCER RESEARCH

IF16.6

2018-08-14

PREAI

Triscott, Joanna; Benelli, Matteo; Sailer, Verena; Prandi, Davide; Emerling, Brooke; Demichelis, Francesca; Cantley, Lewis; Rubin, Mark A.

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Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy

MOLECULAR CELL

IF16.6

2018-05-01

OAAI

Lundquist, Mark R.; Goncalves, Marcus D.; Loughran, Ryan M.; Possik, Elite; Vijayaraghavan, Tarika; Yang, Annan; Pauli, Chantal; Ravi, Archna; Verma, Akanksha; Yang, Zhiwei; Johnson, Jared L.; Wong, Jenny C. Y.; Ma, Yilun; Hwang, Katie Seo-Kyoung; Weinkove, David; Divecha, Nullin; Asara, John M.; Elemento, Olivier; Rubin, Mark A.; Kimmelman, Alec C.; Pause, Arnim; Cantley, Lewis C.; Emerling, Brooke M.

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Fenofibrate prevents skeletal muscle loss in mice with lung cancer (vol 115, pg E743, 2018)

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-02-20

OAAI

Goncalves, Marcus D.; Hwang, Seo-Kyoung; Pauli, Chantal; Murphy, Charles J.; Cheng, Zhe; Hopkins, Benjamin D.; Wu, David; Loughran, Ryan M.; Emerling, Brooke M.; Zhang, Guoan; Fearon, Douglas T.; Cantley, Lewis C.

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Research Directions