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SaveNewly identified properties of known pharmaceuticals and myxobacterial small molecules revealed by screening for autophagy modulators
Fichtner, Janine; Beer, Yan Yan; Ramm, H. G. Mauricio; Muhlen, Sabrina; Surup, Frank; Herrmann, Jennifer; Meister, Toni Luise; Pfaender, Stephanie; Bilitewski, Ursula; Bronstrup, Mark; Mueller, Rolf; Wirth, Manfred; Eskelinen, Eeva-Liisa; Schmitz, Ingo Share Save Accumulation of APP C-terminal fragments causes endolysosomal dysfunction through the dysregulation of late endosome to lysosome-ER contact sitesBretou, Marine; Sannerud, Ragna; Escamilla-Ayala, Abril; Leroy, Tom; Vrancx, Celine; Van Acker, Zoe P.; Perdok, Anika; Vermeire, Wendy; Vorsters, Inge; Van Keymolen, Sophie; Maxson, Michelle; Pavie, Benjamin; Wierda, Keimpe; Eskelinen, Eeva-Liisa; Annaert, Wim Share Save Share Save The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extensionSporbeck, Katharina; Haas, Maximilian L.; Pastor-Maldonado, Carmen J.; Schuessele, David S.; Hunter, Catherine; Takacs, Zsuzsanna; de Oliveira, Ana L. Diogo; Franz-Wachtel, Mirita; Charsou, Chara; Pfisterer, Simon G.; Gubas, Andrea; Haller, Patricia K.; Knorr, Roland L.; Kaulich, Manuel; Macek, Boris; Eskelinen, Eeva-Liisa; Simonsen, Anne; Proikas-Cezanne, Tassula Share Save Share Save Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTsJaved, Ruheena; Jain, Ashish; Duque, Thabata; Hendrix, Emily; Paddar, Masroor Ahmad; Khan, Sajjad; Claude-Taupin, Aurore; Jia, Jingyue; Allers, Lee; Wang, Fulong; Mudd, Michal; Timmins, Graham; Lidke, Keith; Rusten, Tor Erik; Akepati, Prithvi Reddy; He, Yi; Reggiori, Fulvio; Eskelinen, Eeva-Liisa; Deretic, Vojo Share Save Share Save Share Save Share Save Share Save Mitochondrial hyperfusion via metabolic sensing of regulatory amino acidsAbdullah, Mahmud O.; Zeng, Run X.; Margerum, Chelsea L.; Papadopoli, David; Monnin, Cian; Punter, Kaylee B.; Chu, Charles; Al-Rofaidi, Mohammad; Al-Tannak, Naser F.; Berardi, Domenica; Rattray, Zahra; Rattray, Nicholas J. W.; Abraham, Sheela A.; Eskelinen, Eeva-Liisa; Watson, David G.; Avizonis, Daina; Topisirovic, Ivan; Chan, Edmond Y. W. Share Save Share Save Share Save Share Save Synergistic combination of cytotoxic chemotherapy and cyclin-dependent kinase 4/6 inhibitors in biliary tract cancersArora, Mansi; Bogenberger, James M.; Abdelrahman, Amro M.; Yonkus, Jennifer; Alva-Ruiz, Roberto; Leiting, Jennifer L.; Chen, Xianfeng; Uson, Pedro Luiz Serrano, Jr.; Dumbauld, Chelsae R.; Baker, Alexander T.; Gamb, Scott, I; Egan, Jan B.; Zhou, Yumei; Nagalo, Bolni Marius; Meurice, Nathalie; Eskelinen, Eeva-Liisa; Salomao, Marcela A.; Kosiorek, Heidi E.; Braggio, Esteban; Barrett, Michael T.; Buetow, Kenneth H.; Sonbol, Mohamad B.; Mansfield, Aaron S.; Roberts, Lewis R.; Bekaii-Saab, Tanios S.; Ahn, Daniel H.; Truty, Mark J.; Borad, Mitesh J. Share Save Autophagy in major human diseasesKlionsky, Daniel J.; Petroni, Giulia; Amaravadi, Ravi K.; Baehrecke, Eric H.; Ballabio, Andrea; Boya, Patricia; Bravo-San Pedro, Jose Manuel; Cadwell, Ken; Cecconi, Francesco; Choi, Augustine M. K.; Choi, Mary E.; Chu, Charleen T.; Codogno, Patrice; Colombo, Maria Isabel; Cuervo, Ana Maria; Deretic, Vojo; Dikic, Ivan; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fimia, Gian Maria; Gewirtz, David A.; Green, Douglas R.; Hansen, Malene; Jaattela, Marja; Johansen, Terje; Juhasz, Gabor; Karantza, Vassiliki; Kraft, Claudine; Kroemer, Guido; Ktistakis, Nicholas T.; Kumar, Sharad; Lopez-Otin, Carlos; Macleod, Kay F.; Madeo, Frank; Martinez, Jennifer; Melendez, Alicia; Mizushima, Noboru; Munz, Christian; Penninger, Josef M.; Perera, Rushika M.; Piacentini, Mauro; Reggiori, Fulvio; Rubinsztein, David C.; Ryan, Kevin M.; Sadoshima, Junichi; Santambrogio, Laura; Scorrano, Luca; Simon, Hans-Uwe; Simon, Anna Katharina; Simonsen, Anne; Stolz, Alexandra; Tavernarakis, Nektarios; Tooze, Sharon A.; Yoshimori, Tamotsu; Yuan, Junying; Yue, Zhenyu; Zhong, Qing; Galluzzi, Lorenzo; Pietrocola, Federico Share Save The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagyDeneubourg, Celine; Ramm, Mauricio; Smith, Luke J.; Baron, Olga; Singh, Kritarth; Byrne, Susan C.; Duchen, Michael R.; Gautel, Mathias; Eskelinen, Eeva-Liisa; Fanto, Manolis; Jungbluth, Heinz Share Save Share Save Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancerQiao, Yuanyuan; Choi, Jae Eun; Tien, Jean C.; Simko, Stephanie A.; Rajendiran, Thekkelnaycke; Vo, Josh N.; Delekta, Andrew D.; Wang, Lisha; Xiao, Lanbo; Hodge, Nathan B.; Desai, Parth; Mendoza, Sergio; Juckette, Kristin; Xu, Alice; Soni, Tanu; Su, Fengyun; Wang, Rui; Cao, Xuhong; Yu, Jiali; Kryczek, Ilona; Wang, Xiao-Ming; Wang, Xiaoju; Siddiqui, Javed; Wang, Zhen; Bernard, Amelie; Fernandez-Salas, Ester; Navone, Nora M.; Ellison, Stephanie J.; Ding, Ke; Eskelinen, Eeva-Liisa; Heath, Elisabeth I.; Klionsky, Daniel J.; Zou, Weiping; Chinnaiyan, Arul M. Share Save 
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