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FRONTIER-3: a randomised phase 2a study to investigate tozorakimab, an anti-interleukin-33 monoclonal antibody, in early-onset asthma Corren, Jonathan; Reid, Fred; Moate, Rachel; Jimenez, Eulalia; Sadiq, Muhammad Waqas; Williams, Adam; Rytelewski, Mateusz; Cameron-Christie, Sophia; Muthas, Daniel; Georgi, Benjamin; Brooks, Dennis; Lindqvist, Eva; Kell, Chris; Platt, Adam; Belvisi, Maria G.; Pandya, Hitesh Share Save
A novel SPECT-CT imaging platform for quantifying in vivo lung cytokine signals in COPD Welham, Benjamin; Bennett, Michael; Ostridge, Kristoffer; Guy, Matthew; Zvavamwe, Clint; Chilcott, Anna; Johns, Sandra; Sundram, Francis; Spalluto, Cosma M.; Shaw, Emily; Harden, Stephen; Alzetani, Aiman; Lee, Paul; Lawson, Matthew; Lackie, Peter; Michopoulou, Sofia; Henley, Darren; Kong, Alex; Fazleen, Aishath; Cellura, Doriana; Mccrae, Christopher; Platt, Adam; Belvisi, Maria G.; Staples, Karl J.; Wilkinson, Tom Share Save
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NTHi killing activity is reduced in COPD patients and is associated with a differential microbiome Gopalakrishnan, Vancheswaran; Sparklin, Ben; Kim, Jung Hwan; Bouquet, Jerome; Kehl, Margaret; Kenny, Tara; Morehouse, Christopher; Caceres, Carolina; Warrener, Paul; Hristova, Ventzislava A.; Wilson, Susan; Shandilya, Harini; Barnes, Arnita; Ruzin, Alexey; Wang, Junmin; Oberg, Lisa; Angermann, Bastian; Mccrae, Christopher; Platt, Adam; Muthas, Daniel; Hess, Sonja; Tkaczyk, Christine; Sellman, Bret R.; Ostridge, Kristoffer; Belvisi, Maria G.; Wilkinson, Tom M. A.; Staples, Karl J.; Digiandomenico, Antonio; MICA II Study Grp, Vancheswaran Share Save
AZD7798, a monoclonal antibody depleting CCR9+T cells, with the potential to target hard-to-treat small bowel Crohn's disease Powell, N.; Hedin, C.; Harper, A. R.; Mackay, J.; Lundin, P.; Bock, D.; Spata, E.; Bouma, G.; Tian, S.; Lundahl, A.; Lund, J.; Eck, S.; Popinska, A.; Strombeck, A.; Fowler, A.; Eberhardson, M.; Belvisi, M.; Marks, D. J. B. Share Save
Imaging of CCR9 in the small bowel of patients with Crohn's disease: effects of the CCR9-depleting monoclonal antibody AZD7798 Hedin, C. R.; Creignou, M.; Mackay, J.; Jucaite, A.; Cselenyi, Z.; Johnstrom, P.; Dahl, K.; Schou, M.; Cortes Gonzalez, M. A.; Hognasbacka, A.; Stenkrona, P.; Blomqvist, L. K.; Cananau, C.; Palmer, E.; Bouma, G.; Eck, S.; Lund, J.; Lundahl, A.; Kiraga, J.; Popinska, A.; Eberhardson, M.; Belvisi, M. G.; Marks, D. J. B. Share Save
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Plasma and bronchoalveolar lavage ATP in refractory/unexplained chronic cough Digby, James Wingfield; Wortley, Michael; Bonvini, Sara; Dockry, Rachel; Issop, Sabina; King, Jenny; Massey, Bethany; Stephan, Simon; Dubois, Eric; Galgani, Shannon; Holt, Kimberley; Sen, Shilpi; Mitchell, Joanne; Al-Sheklly, Bashar; Belvisi, Maria; Smith, Jacky; Marsden, Paul Share Save
Percentage Ciliation in Bronchiectasis Patient Upper and Lower Airways Cant, Erin; Shuttleworth, Morven; Johnson, Emma; Pembridge, Thomas; Bidgood, Lucy; Lind, Holly; Crichton, Megan L.; Viligorska, Kateryna; Connell, David W.; Liddicoat, Helen; Long, Merete; Platt, Adam; Belvisi, Maria; Ostridge, Kristoffer; Chalmers, James; Shoemark, Amelia Share Save
CD39L1 levels in refractory/unexplained chronic cough patients, and relationship to cough counts Wortley, Michael A.; Digby, James Wingfield; Issop, Sabina; Bonvini, Sara J.; Dockry, Rachel; King, Jenny; Massey, Beth; Stephan, Simon; Al-Sheklly, Bashar; Belvisi, Maria G.; Dubuis, Eric D.; Galgani, Shannon; Holt, Kimberley; Sen, Shilpi; Marsden, Paul; Smith, Jacky A. Share Save
Clinical trial interest from patients with COPD approached after Lung Cancer Screening Patrick, Tanya; Aboelhassan, Arafa; Parenti, Marta; Mugambwa, Alice; Moody, Jayce; Voase, Nia; Blackstone, Katherine; Macwan, Anika; Scully, Kim; Cano, Silvia; Doffman, Sarah; Maria, Doffman; Belvisi, Maria; Bhamani, Amyn; Janes, Sam M.; Hurst, John R. Share Save
Evaluation of rapid multiplex PCR for investigation of lung microbiology in bronchiectasis - preliminary data from the BRILLIANT study Bidgood, Lucy; Richardson, Hollian; Headley, Daniela Alferes De Lima; Hennayake, Chandani; Pembridge, Thomas; Johnson, Emma; Lind, Holly; Shuttleworth, Morven; Viligorska, Kateryna; Cant, Erin; Crichton, Megan; Liddicoat, Helen; Connell, David; Shoemark, Amelia; Mcintosh, Eve; Ostridge, Kris; Platt, Adam; Belvisi, Maria; Long, Merete; Dicker, Alison J.; Chalmers, James Share Save
ARTEMISIA: A JAK1 inhibitor mechanistic study to advance molecular understanding and precision medicine in respiratory diseases Rojnik, Zala Jevnikar; Dosanjh, Davinder P. S.; Jensen, Tina Jellesmark; Darrah, Erika; Torell, Jenny; Halvorson, Alese; Cardner, Mathias; Riff, Camille; Muthas, Daniel; Chamberlain, Chris; Platt, Adam; Belvisi, Maria; Hughes, Rod; Konstantinidis, Kyriakos, V; Brightling, Christopher E. Share Save
Airway neutrophils are primed for neutrophil extracellular trap formation in bronchiectasis: preliminary data from the BRILLIANT cohort study Pembridge, Thomas; Johnson, Emma; Lind, Holly; Mcintosh, Eve; Shuttleworth, Morven; Viligorska, Kateryna; Crichton, Megan; Liddicoat, Helen; Connell, Dave; Shoemark, Amelia; Dicker, Alison; Bidgood, Lucy; Cant, Erin; Ostridge, Kris; Belvisi, Maria; Platt, Adam; Long, Merete; Chalmers, James Share Save
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APATURA: a Phase 2a study of elarekibep, an inhaled IL-4 receptor alpha inhibitor, in moderate-to-severe asthma Hugo, Tania; Harper, Andrew R.; Leander, Jacob; Lundin, Pa; Bock, David; Zhou, Xiao-Hong; Bondarenko, Irina; Burns, Steve; Wiegert, Erol; Fitzgerald, Mary F.; Close, David R.; Keeling, David J.; Pandya, Hitesh; Belvisi, Maria G.; O'Byrne, Paul M. Share Save
Deep Learning-based Segmentation of Computed Tomography Scans Predicts Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis Thillai, Muhunthan; Oldham, Justin M.; Ruggiero, Alessandro; Kanavati, Fahdi; McLellan, Tom; Saini, Gauri; Johnson, Simon R.; Ble, Francois-Xavier; Azim, Adnan; Ostridge, Kristoffer; Platt, Adam; Belvisi, Maria; Maher, Toby M.; Molyneaux, Philip L. Share Save
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