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J

J. Wade Harper

harvard medical school

141H-index
461Paper Count
9.9WCitation Count
Published Papers 198
Publication Date
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Membrane bridges and nanodomain partitioning govern membrane protein targeting to lipid droplets
errNature Cell Biology
IF19.1
err2026-05-26
err0
errOAAI
errArda Mizrak; Jacob Kæstel-Hansen; Jessica Matthias; J. Wade Harper; Nikos S. Hatzakis; Robert V. Farese; Tobias C. Walther
errShare
errSave
Publisher Correction: Multimodal cell maps as a foundation for structural and functional genomics
errNature
IF48.5
err2025-10-02
err0
errOAAI
errLeah V. Schaffer; Mengzhou Hu; Gege Qian; Kyung-Mee Moon; Abantika Pal; Neelesh Soni; Andrew P. Latham; Laura Pontano Vaites; Dorothy Tsai; Nicole M. Mattson; Katherine Licon; Robin Bachelder; Anthony Cesnik; Ishan Gaur; Trang Le; William Leineweber; Aji Palar; Ernst Pulido; Yue Qin; Xiaoyu Zhao; Christopher Churas; Joanna Lenkiewicz; Jing Chen; Keiichiro Ono; Dexter Pratt; Peter Zage; Ignacia Echeverria; Andrej Sali; J. Wade Harper; Steven P. Gygi; Leonard J. Foster; Edward L. Huttlin; Emma Lundberg; Trey Ideker
errShare
errSave
α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation
errMolecular Cell
IF16.6
err2025-09-10
err0
errOAAI
errCole S. Sitron; Victoria A. Trinkaus; Ana Galesic; Maximilian Garhammer; Patricia Yuste-Checa; Ulrich Dransfeld; Dennis Feigenbutz; Jiuchun Zhang; Larysa Ivashko; Irina Dudanova; J. Wade Harper; F. Ulrich Hartl
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errSave
Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation
errCell
IF42.5
err2025-08-27
err0
errOAAI
errJingchuan Luo; Stuti Khandwala; Jingjie Hu; Song-Yi Lee; Kelsey L. Hickey; Zebulon G. Levine; J. Wade Harper; Alice Y. Ting; Jonathan S. Weissman
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errSave
EndoMAP.v1 charts the structural landscape of human early endosome complexes
errNATURE
IF48.5
err2025-05-28
err0
errOAAI
errGonzalez-Lozano, Miguel A.; Schmid, Ernst W.; Whelan, Enya Miguel; Jiang, Yizhi; Paulo, Joao A.; Walter, Johannes C.; Harper, J. Wade
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errSave
Combinatorial selective ER-phagy remodels the ER during neurogenesis (vol 26, pg 378, 2024)
errNATURE CELL BIOLOGY
IF19.1
err2025-04-15
err0
errOAAI
errHoyer, Melissa J.; Capitanio, Cristina; Smith, Ian R.; Paoli, Julia C.; Bieber, Anna; Jiang, Yizhi; Paulo, Joao A.; Gonzalez-Lozano, Miguel A.; Baumeister, Wolfgang; Wilfling, Florian; Schulman, Brenda A.; Harper, J. Wade
errShare
errSave
ARMC1 partitions between distinct complexes and assembles MIRO with MTFR to control mitochondrial distribution
errSCIENCE ADVANCES
IF12.5
err2025-04-11
err0
PREAI
errMcKenna, Michael J.; Kraus, Felix; Coelho, Joao P. L.; Vasandani, Muskaan; Zhang, Jiuchun; Adams, Benjamin M.; Paulo, Joao A.; Harper, J. Wade
errShare
errSave
The network response to Egf is tissue-specific
errISCIENCE
IF4.1
err2025-04-01
err0
errOAAI
errAwasthi, Beatrice W.; Paulo, Joao A.; Burkhart, Deborah L.; Smith, Ian R.; Collins, Ryan L.; Harper, J. Wade; Gygi, Steven P.; Haigis, Kevin M.
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errSave
Temporal control of acute protein aggregate turnover by UBE3C and NRF1-dependent proteasomal pathways
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-12-05
err0
errOAAI
errHickey, Kelsey L.; Panov, Alexandra; Whelan, Enya Miguel; Schaefer, Tillman; Mizrak, Arda; Kopito, Ron R.; Baumeister, Wolfgang; Fernandez-Busnadiego, Ruben; Harper, J. Wade
errShare
errSave
Endo- IP and lyso- IP toolkit for endolysosomal profiling of human- induced neurons
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-12-05
err0
errOAAI
errHundley, Frances, V; Gonzalez-Lozano, Miguel A.; Gottschalk, Lena M.; Cook, Aslan N. K.; Zhang, Jiuchun; Paulo, Joao A.; Harper, J. Wade
errShare
errSave
Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases
errNATURE COMMUNICATIONS
IF15.7
err2024-11-15
err0
errOAAI
errScott, Daniel C.; Chittori, Sagar; Purser, Nicholas; King, Moeko T.; Maiwald, Samuel A.; Churion, Kelly; Nourse, Amanda; Lee, Chan; Paulo, Joao A.; Miller, Darcie J.; Elledge, Stephen J.; Harper, J. Wade; Kleiger, Gary; Schulman, Brenda A.
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errSave
Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2
errNATURE COMMUNICATIONS
IF15.7
err2024-10-12
err0
errOAAI
errScott, Daniel C.; Dharuman, Suresh; Griffith, Elizabeth; Chai, Sergio C.; Ronnebaum, Jarrid; King, Moeko T.; Tangallapally, Rajendra; Lee, Chan; Gee, Clifford T.; Yang, Lei; Li, Yong; Loudon, Victoria C.; Lee, Ha Won; Ochoada, Jason; Miller, Darcie J.; Jayasinghe, Thilina; Paulo, Joao A.; Elledge, Stephen J.; Harper, J. Wade; Chen, Taosheng; Lee, Richard E.; Schulman, Brenda A.
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errSave
Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2024-04-10
err4
errOAAI
errAdolf, Frank; Du, Jiale; Goodall, Ellen A.; Walsh Jr, Richard M.; Rawson, Shaun; von Gronau, Susanne; Harper, J. Wade; Hanna, John; Schulman, Brenda A.
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errSave
A global multiscale map of protein assemblies from integration of protein interactions and images
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errSchaffer, Leah V.; Hu, Mengzhou; Huttlin, Edward L.; Qian, Gege; Pal, Abantika; Soni, Neelesh; Latham, Andrew; Vaites, Laura Pontano; Trang Le; Qin, Yue; Churas, Christopher; Pratt, Dexter; Echeverria, Ignacia; Sali, Andrej; Harper, J. Wade; Gygi, Steven P.; Lundberg, Emma; Ideker, Trey
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errSave
A map of osteosarcoma cell architecture reveals convergence of pediatric cancer mutations on protein assemblies
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHu, Mengzhou; Schaffer, Leah V.; Huttlin, Edward L.; Qian, Gege; Latham, Andrew; Pal, Abantika; Vaites, Laura Pontano; Le, Trang; Qin, Yue; Churas, Christopher; Pratt, Dexter; Bachelder, Robin; Zage, Peter; Echeverria, Ignacia; Sali, Andrej; Harper, J. Wade; Gygi, Steven P.; Lundberg, Emma; Ideker, Trey
errShare
errSave
Combinatorial selective ER-phagy remodels the ER during neurogenesis
errNATURE CELL BIOLOGY
IF19.1
err2024-03-01
err5
errOAAI
errHoyer, Melissa J.; Capitanio, Cristina; Smith, Ian R.; Paoli, Julia C.; Bieber, Anna; Jiang, Yizhi; Paulo, Joao A.; Gonzalez-Lozano, Miguel A.; Baumeister, Wolfgang; Wilfling, Florian; Schulman, Brenda A.; Harper, J. Wade
errShare
errSave
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons (vol 110, pg 967, 2022)
errNEURON
IF15
err2024-02-01
err1
errOAAI
errGoldsmith, Juliet; Ordureau, Alban; Harper, J. Wade; Holzbaur, Erika L. F.
errShare
errSave
Systematic analysis of nonprogrammed frameshift suppression in E. coli via translational tiling proteomics
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-01-30
err0
errOAAI
errSpringstein, Benjamin L.; Paulo, Joao A.; Park, Hankum; Henry, Kemardo; Fleming, Eleanor; Feder, Zoe; Harper, J. Wade; Hochschild, Ann; Zaher, Hani S.
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errSave
Analyzing the ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets
errFRONTIERS IN CELLULAR NEUROSCIENCE
IF4
err2024-01-19
err0
errOAAI
errWatts, Michelle E.; Giadone, Richard M.; Ordureau, Alban; Holton, Kristina M.; Harper, J. Wade; Rubin, Lee L.
errShare
errSave
ER membrane curvature and ubiquitin as drivers of ER-phagy
errDEVELOPMENTAL CELL
IF8.7
err2023-07-01
err0
errOAAI
errHoyer, Melissa J.; Harper, J. Wade
errShare
errSave

Research Directions

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