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Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases Zheng, Bang; Campbell, Jacqueline; Carr, Edward J.; Tazare, John; Nab, Linda; Mahalingasivam, Viyaasan; Mehrkar, Amir; Santhakumaran, Shalini; Steenkamp, Retha; Loud, Fiona; Lyon, Susan; Scanlon, Miranda; Hulme, William J.; Green, Amelia C. A.; Curtis, Helen J.; Fisher, Louis; Parker, Edward; Ben Goldacre; Douglas, Ian; Evans, Stephen; MacKenna, Brian; Bell, Samira; Tomlinson, Laurie A.; Nitsch, Dorothea Share Save
Challenges in Estimating the Effectiveness of COVID-19 Vaccination Using Observational Data Hulme, William J.; Williamson, Elizabeth; Horne, Elsie M. F.; Green, Amelia; McDonald, Helen I. I.; Walker, Alex J. J.; Curtis, Helen J. J.; Morton, Caroline E.; MacKenna, Brian; Croker, Richard; Mehrkar, Amir; Bacon, Seb; Evans, David; Inglesby, Peter; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T.; Tomlinson, Laurie; Douglas, Ian J.; Evans, Stephen J. W.; Smeeth, Liam; Palmer, Tom; Goldacre, Ben; Hernan, Miguel A.; Sterne, Jonathan A. C. Share Save
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY Green, Amelia C. A.; Curtis, Helen J.; Higgins, Rose; Nab, Linda; Mahalingasivam, Viyaasan; Smith, Rebecca M.; Mehrkar, Amir; Inglesby, Peter; Drysdale, Henry; Devito, Nicholas J.; Croker, Richard; Rentsch, Christopher T.; Bhaskaran, Krishnan; Tazare, John; Zheng, Bang; Andrews, Colm D.; Bacon, Sebastian C. J.; Davy, Simon; Dillingham, Iain; Evans, David; Fisher, Louis; Hickman, George; Hopcroft, Lisa E. M.; Hulme, William J.; Massey, Jon; Macdonald, Orla; Morley, Jessica; Morton, Caroline E.; Park, Robin Y.; Walker, Alex J.; Ward, Tom; Wiedemann, Milan; Bates, Christopher; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J.; Evans, Stephen J. W.; Goldacre, Ben; Tomlinson, Laurie A.; Mackenna, Brian Share Save
Identifying Patterns of Clinical Interest in Clinicians? Treatment Preferences: Hypothesis-free Data Science Approach to Prioritizing Prescribing Outliers for Clinical Review MacKenna, Brian; Curtis, Helen J.; Hopcroft, Lisa E. M.; Walker, Alex J.; Croker, Richard; Macdonald, Orla; Evans, Stephen J. W.; Inglesby, Peter; Evans, David; Morley, Jessica; Bacon, Sebastian C. J.; Goldacre, Ben Share Save
Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform Zheng, Bang; Green, Amelia C. A.; Tazare, John; Curtis, Helen J.; Fisher, Louis; Nab, Linda; Schultze, Anna; Mahalingasivam, Viyaasan; Parker, Edward P. K.; Hulme, William J.; Bacon, Sebastian C. J.; DeVito, Nicholas J.; Bates, Christopher; Evans, David; Inglesby, Peter; Drysdale, Henry; Davy, Simon; Cockburn, Jonathan; Morton, Caroline E.; Hickman, George; Ward, Tom; Smith, Rebecca M.; Parry, John; Hester, Frank; Harper, Sam; Mehrkar, Amir; Eggo, Rosalind M.; Walker, Alex J.; Evans, Stephen J. W.; Douglas, Ian J.; MacKenna, Brian; Goldacre, Ben; Tomlinson, Laurie A. Share Save
Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY Hulme, William J.; Williamson, Elizabeth J.; Green, Amelia C. A.; Bhaskaran, Krishnan; McDonald, Helen, I; Rentsch, Christopher T.; Schultze, Anna; Tazare, John; Curtis, Helen J.; Walker, Alex J.; Tomlinson, Laurie A.; Palmer, Tom; Horne, Elsie M. F.; MacKenna, Brian; Morton, Caroline E.; Mehrkar, Amir; Morley, Jessica; Fisher, Louis; Bacon, Sebastian C. J.; Evans, David; Inglesby, Peter; Hickman, George; Davy, Simon; Ward, Tom; Croker, Richard; Eggo, Rosalind M.; Wong, Angel Y. S.; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Grint, Daniel J.; Douglas, Ian J.; Evans, Stephen J. W.; Smeeth, Liam; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Sterne, Jonathan A. C.; Hernan, Miguel A.; Goldacre, Ben Share Save
Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY Green, Amelia; Curtis, Helen; Hulme, William; Williamson, Elizabeth; McDonald, Helen; Bhaskaran, Krishnan; Rentsch, Christopher; Schultze, Anna; MacKenna, Brian; Mahalingasivam, Viyaasan; Tomlinson, Laurie; Walker, Alex; Fisher, Louis; Massey, Jon; Andrews, Colm; Hopcroft, Lisa; Morton, Caroline; Croker, Richard; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Evans, David; Inglesby, Peter; Hickman, George; Ward, Tom; Davy, Simon; Mathur, Rohini; Tazare, John; Eggo, Rosalind; Wing, Kevin; Wong, Angel; Forbes, Harriet; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Evans, Stephen; Smeeth, Liam; Goldacre, Ben Share Save
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform MacKenna, Brian; Kennedy, Nicholas A.; Mehrkar, Amir; Rowan, Anna; Galloway, James; Matthewman, Julian; Mansfield, Kathryn E.; Bechman, Katie; Yates, Mark; Brown, Jeremy; Schultze, Anna; Norton, Sam; Walker, Alex J.; Morton, Caroline E.; Harrison, David; Bhaskaran, Krishnan; Rentsch, Christopher T.; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hickman, George; Ward, Tom; Davy, Simon; Green, Amelia; Fisher, Louis; Hulme, William; Bates, Chris; Curtis, Helen J.; Tazare, John; Eggo, Rosalind M.; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen, I; Tomlinson, Laurie A.; Mathur, Rohini; Wong, Angel Y. S.; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J.; Smeeth, Liam; Lees, Charlie W.; Evans, Stephen J. W.; Goldacre, Ben; Smith, Catherine H.; Langan, Sinead M. Share Save
Potentially inappropriate prescribing of DOACs to people with mechanical heart valves: A federated analysis of 57.9 million patients' primary care records in situ using OpenSAFELY Fisher, Louis; Speed, Victoria; Curtis, Helen J.; Rentsch, Christopher T.; Wong, Angel Y. S.; Schultze, Anna; Massey, Jon; Inglesby, Peter; Morton, Caroline E.; Wood, Marion; Walker, Alex J.; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Smith, Becky; Williamson, Elizabeth; Hulme, William; Green, Amelia; Eggo, Rosalind M.; Forbes, Harriet; Tazare, John; Parry, John; Hester, Frank; Harper, Sam; Meadows, Jonathan; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J.; Evans, Stephen J. W.; Smeeth, Liam; MacKenna, Brian; Tomlinson, Laurie; Goldacre, Ben Share Save
Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65 Schultze, Anna; Nightingale, Emily; Evans, David; Hulme, William; Rosello, Alicia; Bates, Chris; Cockburn, Jonathan; MacKenna, Brian; Curtis, Helen J.; Morton, Caroline E.; Croker, Richard; Bacon, Seb; McDonald, Helen, I; Rentsch, Christopher T.; Bhaskaran, Krishnan; Mathur, Rohini; Tomlinson, Laurie A.; Williamson, Elizabeth J.; Forbes, Harriet; Tazare, John; Grint, Daniel; Walker, Alex J.; Inglesby, Peter; DeVito, Nicholas J.; Mehrkar, Amir; Hickman, George; Davy, Simon; Ward, Tom; Fisher, Louis; Green, Amelia C. A.; Wing, Kevin; Wong, Angel Y. S.; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen J. W.; Douglas, Ian J.; Smeeth, Liam; Eggo, Rosalind M.; Goldacre, Ben; Leon, David A. Share Save
Association between oral anticoagulants and COVID-19-related outcomes: a population-based cohort study Wong, Angel Y. S.; Tomlinson, Laurie; Brown, Jeremy P.; Elson, William; Walker, Alex J.; Schultze, Anna; Morton, Caroline E.; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J.; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen, I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M.; Evans, Stephen J. W.; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J. Share Save
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform Bhaskaran, Krishnan; Rentsch, Christopher T.; Hickman, George; Hulme, William J.; Schultze, Anna; Curtis, Helen J.; Wing, Kevin; Warren-Gash, Charlotte; Tomlinson, Laurie; Bates, Chris J.; Mathur, Rohini; MacKenna, Brian; Mahalingasivam, Viyaasan; Wong, Angel; Walker, Alex J.; Morton, Caroline E.; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M.; Inglesby, Peter; Douglas, Ian J.; McDonald, Helen I.; Cockburn, Jonathan; Williamson, Elizabeth J.; Evans, David; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen J. W.; Bacon, Sebastian; Smeeth, Liam; Goldacre, Ben Share Save
Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study Wong, Angel Y. S.; Tomlinson, Laurie A.; Brown, Jeremy P.; Elson, William; Walker, Alex J.; Schultze, Anna; Morton, Caroline E.; Evans, David; Inglesby, Peter; MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T.; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J.; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I.; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M.; Evans, Stephen J. W.; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J. Share Save
Trends and clinical characteristics of 57.9 million COVID-19 vaccine recipients: a federated analysis of patients' primary care records in situ using OpenSAFELY Curtis, Helen J.; Inglesby, Peter; Morton, Caroline E.; MacKenna, Brian; Green, Amelia; Hulme, William; Walker, Alex J.; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T.; Williamson, Elizabeth J.; Rowan, Anna; Fisher, Louis; McDonald, Helen, I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M.; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J.; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben Share Save
OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19 Curtis, Helen J.; MacKenna, Brian; Croker, Richard; Inglesby, Peter; Walker, Alex J.; Morley, Jessica; Mehrkar, Amir; Morton, Caroline E.; Bacon, Seb; Hickman, George; Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T.; Williamson, Elizabeth J.; Hulme, William J.; McDonald, Helen, I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M.; Wing, Kevin; Wong, Angel Y. S.; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen J. W.; Douglas, Ian J.; Smeeth, Liam; Goldacre, Ben Share Save
Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England Grint, Daniel J.; Wing, Kevin; Houlihan, Catherine; Gibbs, Hamish P.; Evans, Stephen J. W.; Williamson, Elizabeth; McDonald, Helen, I; Bhaskaran, Krishnan; Evans, David; Walker, Alex J.; Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T.; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J.; Morton, Caroline E.; Bacon, Sebastian; Davy, Simon; Wong, Angel Y. S.; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J.; Mathur, Rohini; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J.; Hulme, Will; Tazare, John; Smeeth, Liam; Goldacre, Ben; Eggo, Rosalind M. Share Save
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