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The role of MLH1, MSH2 and MSH6 in the development of colorectal cancer in Uganda Wismayer, Richard; Matthews, Rosie; Whalley, Celina; Kiwanuka, Julius; Kakembo, Fredrick Elishama; Thorn, Steve; Wabinga, Henry; Odida, Michael; Tomlinson, Ian Share Save
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis Schoenpflug, Lydia A.; Chatzipli, Aikaterini; Sirinukunwattana, Korsuk; Richman, Susan; Blake, Andrew; Robineau, James; Mertz, Kirsten D.; Verrill, Clare; Leedham, Simon J.; Hardy, Claire; Whalley, Celina; Redmond, Keara; Dunne, Philip; Walker, Steven; Beggs, Andrew D.; Mcdermott, Ultan; Murray, Graeme, I; Samuel, Leslie M.; Seymour, Matthew; Tomlinson, Ian; Quirke, Philip; S CORT Consortium, Jens; Rittscher, Jens; Maughan, Tim; Domingo, Enric; Koelzer, Viktor H. Share Save
Germline copy number variants and endometrial cancer risk Stylianou, Cassie E.; Wiggins, George A. R.; Lau, Vanessa L.; Dennis, Joe; Shelling, Andrew N.; Wilson, Michelle; Sykes, Peter; Amant, Frederic; Annibali, Daniela; De Wispelaere, Wout; Easton, Douglas F.; Fasching, Peter A.; Glubb, Dylan M.; Goode, Ellen L.; Lambrechts, Diether; Pharoah, Paul D. P.; Scott, Rodney J.; Tham, Emma; Tomlinson, Ian; Bolla, Manjeet K.; Couch, Fergus J.; Czene, Kamila; Doerk, Thilo; Dunning, Alison M.; Fletcher, Olivia; Garcia-Closas, Montserrat; Hoppe, Reiner; Jernstrom, Helena; Kaaks, Rudolf; Michailidou, Kyriaki; Obi, Nadia; Southey, Melissa C.; Stone, Jennifer; Wang, Qin; Spurdle, Amanda B.; O'Mara, Traacy A.; Pearson, John; Walker, Logan C. Share Save
Determination of the frequency and distribution of APC, PIK3CA, and SMAD4 gene mutations in Ugandan patients with colorectal cancer Wismayer, Richard; Matthews, Rosie; Whalley, Celina; Kiwanuka, Julius; Kakembo, Fredrick Elishama; Thorn, Steve; Wabinga, Henry; Odida, Michael; Tomlinson, Ian Share Save
Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes Chen, Zhishan; Guo, Xingyi; Tao, Ran; Huyghe, Jeroen R.; Law, Philip J.; Fernandez-Rozadilla, Ceres; Ping, Jie; Jia, Guochong; Long, Jirong; Li, Chao; Shen, Quanhu; Xie, Yuhan; Timofeeva, Maria N.; Thomas, Minta; Schmit, Stephanie L.; Diez-Obrero, Virginia; Devall, Matthew; Moratalla-Navarro, Ferran; Fernandez-Tajes, Juan; Palles, Claire; Sherwood, Kitty; Briggs, Sarah E. W.; Svinti, Victoria; Donnelly, Kevin; Farrington, Susan M.; Blackmur, James; Vaughan-Shaw, Peter G.; Shu, Xiao-Ou; Lu, Yingchang; Broderick, Peter; Studd, James; Harrison, Tabitha A.; Conti, David V.; Schumacher, Fredrick R.; Melas, Marilena; Rennert, Gad; Obon-Santacana, Mireia; Martin-Sanchez, Vicente; Oh, Jae Hwan; Kim, Jeongseon; Jee, Sun Ha; Jung, Keum Ji; Kweon, Sun-Seog; Shin, Min-Ho; Shin, Aesun; Ahn, Yoon-Ok; Kim, Dong-Hyun; Oze, Isao; Wen, Wanqing; Matsuo, Keitaro; Matsuda, Koichi; Tanikawa, Chizu; Ren, Zefang; Gao, Yu-Tang; Jia, Wei-Hua; Hopper, John L.; Jenkins, Mark A.; Win, Aung Ko; Pai, Rish K.; Figueiredo, Jane C.; Haile, Robert W.; Gallinger, Steven; Woods, Michael O.; Newcomb, Polly A.; Duggan, David; Cheadle, Jeremy P.; Kaplan, Richard; Kerr, Rachel; Kerr, David; Kirac, Iva; Bohm, Jan; Mecklin, Jukka-Pekka; Jousilahti, Pekka; Knekt, Paul; Aaltonen, Lauri A.; Rissanen, Harri; Pukkala, Eero; Eriksson, Johan G.; Cajuso, Tatiana; Hanninen, Ulrika; Kondelin, Johanna; Palin, Kimmo; Tanskanen, Tomas; Renkonen-Sinisalo, Laura; Mannisto, Satu; Albanes, Demetrius; Weinstein, Stephanie J.; Ruiz-Narvaez, Edward; Palmer, Julie R.; Buchanan, Daniel D.; Platz, Elizabeth A.; Visvanathan, Kala; Ulrich, Cornelia M.; Siegel, Erin; Brezina, Stefanie; Gsur, Andrea; Campbell, Peter T.; Chang-Claude, Jenny; Hoffmeister, Michael; Brenner, Hermann; Slattery, Martha L.; Potter, John D.; Tsilidis, Kostas K.; Schulze, Matthias B.; Gunter, Marc J.; Murphy, Neil; Castells, Antoni; Castellvi-Bel, Sergi; Moreira, Leticia; Arndt, Volker; Shcherbina, Anna; Bishop, D. Timothy; Giles, Graham G.; Southey, Melissa C.; Idos, Gregory E.; McDonnell, Kevin J.; Abu-Ful, Zomoroda; Greenson, Joel K.; Shulman, Katerina; Lejbkowicz, Flavio; Offit, Kenneth; Su, Yu-Ru; Steinfelder, Robert; Keku, Temitope O.; van Guelpen, Bethany; Hudson, Thomas J.; Hampel, Heather; Pearlman, Rachel; Berndt, Sonja I.; Hayes, Richard B.; Martinez, Marie Elena; Thomas, Sushma S.; Pharoah, Paul D. P.; Larsson, Susanna C.; Yen, Yun; Lenz, Heinz-Josef; White, Emily; Li, Li; Doheny, Kimberly F.; Pugh, Elizabeth; Shelford, Tameka; Chan, Andrew T.; Cruz-Correa, Marcia; Lindblom, Annika; Hunter, David J.; Joshi, Amit D.; Schafmayer, Clemens; Scacheri, Peter C.; Kundaje, Anshul; Schoen, Robert E.; Hampe, Jochen; Stadler, Zsofia K.; Vodicka, Pavel; Vodickova, Ludmila; Vymetalkova, Veronika; Edlund, Christopher K.; Gauderman, W. James; Shibata, David; Toland, Amanda; Markowitz, Sanford; Kim, Andre; Chanock, Stephen J.; van Duijnhoven, Franzel; Feskens, Edith J. M.; Sakoda, Lori C.; Gago-Dominguez, Manuela; Wolk, Alicja; Pardini, Barbara; FitzGerald, Liesel M.; Lee, Soo Chin; Ogino, Shuji; Bien, Stephanie A.; Kooperberg, Charles; Li, Christopher I.; Lin, Yi; Prentice, Ross; Qu, Conghui; Bezieau, Stephane; Yamaji, Taiki; Sawada, Norie; Iwasaki, Motoki; Le Marchand, Loic; Wu, Anna H.; Qu, Chenxu; McNeil, Caroline E.; Coetzee, Gerhard; Hayward, Caroline; Deary, Ian J.; Harris, Sarah E.; Theodoratou, Evropi; Reid, Stuart; Walker, Marion; Ooi, Li Yin; Lau, Ken S.; Zhao, Hongyu; Hsu, Li; Cai, Qiuyin; Dunlop, Malcolm G.; Gruber, Stephen B.; Houlston, Richard S.; Moreno, Victor; Casey, Graham; Peters, Ulrike; Tomlinson, Ian; Zheng, Wei Share Save
Population screening requires robust evidence-genomics is no exception Turnbull, Clare; Firth, Helen, V; Wilkie, Andrew O. M.; Newman, William; Raymond, F. Lucy; Tomlinson, Ian; Lachmann, Robin; Wright, Caroline F.; Wordsworth, Sarah; George, Angela; Mccartney, Margaret; Lucassen, Anneke Share Save
Adult stem cell activity in naked mole rats for long-term tissue maintenance Montazid, Shamir; Bandyopadhyay, Sheila; Hart, Daniel W.; Gao, Nan; Johnson, Brian; Thrumurthy, Sri G.; Penn, Dustin J.; Wernisch, Bettina; Bansal, Mukesh; Altrock, Philipp M.; Rost, Fabian; Gazinska, Patrycja; Ziolkowski, Piotr; Hayee, Bu Hussain; Liu, Yue; Han, Jiangmeng; Tessitore, Annamaria; Koth, Jana; Bodmer, Walter F.; East, James E.; Bennett, Nigel C.; Tomlinson, Ian; Irshad, Shazia Share Save
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations Thomas, Minta; Su, Yu-Ru; Rosenthal, Elisabeth A.; Sakoda, Lori C.; Schmit, Stephanie L.; Timofeeva, Maria N.; Chen, Zhishan; Fernandez-Rozadilla, Ceres; Law, Philip J.; Murphy, Neil; Carreras-Torres, Robert; Diez-Obrero, Virginia; van Duijnhoven, Franzel J. B.; Jiang, Shangqing; Shin, Aesun; Wolk, Alicja; Phipps, Amanda I.; Burnett-Hartman, Andrea; Gsur, Andrea; Chan, Andrew T.; Zauber, Ann G.; Wu, Anna H.; Lindblom, Annika; Um, Caroline Y.; Tangen, Catherine M.; Gignoux, Chris; Newton, Christina; Haiman, Christopher A.; Qu, Conghui; Bishop, D. Timothy; Buchanan, Daniel D.; Crosslin, David R.; Conti, David V.; Kim, Dong-Hyun; Hauser, Elizabeth; White, Emily; Siegel, Erin; Schumacher, Fredrick R.; Rennert, Gad; Giles, Graham G.; Hampel, Heather; Brenner, Hermann; Oze, Isao; Oh, Jae Hwan; Lee, Jeffrey K.; Schneider, Jennifer L.; Chang-Claude, Jenny; Kim, Jeongseon; Huyghe, Jeroen R.; Zheng, Jiayin; Hampe, Jochen; Greenson, Joel; Hopper, John L.; Palmer, Julie R.; Visvanathan, Kala; Matsuo, Keitaro; Matsuda, Koichi; Jung, Keum Ji; Li, Li; Le Marchand, Loic; Vodickova, Ludmila; Bujanda, Luis; Gunter, Marc J.; Matejcic, Marco; Jenkins, Mark A.; Slattery, Martha L.; D'Amato, Mauro; Wang, Meilin; Hoffmeister, Michael; Woods, Michael O.; Kim, Michelle; Song, Mingyang; Iwasaki, Motoki; Du, Mulong; Udaltsova, Natalia; Sawada, Norie; Vodicka, Pavel; Campbell, Peter T.; Newcomb, Polly A.; Cai, Qiuyin; Pearlman, Rachel; Pai, Rish K.; Schoen, Robert E.; Steinfelder, Robert S.; Haile, Robert W.; Vandenputtelaar, Rosita; Prentice, Ross L.; Kuery, Sebastien; Castellvi-Bel, Sergi; Tsugane, Shoichiro; Berndt, Sonja I.; Lee, Soo Chin; Brezina, Stefanie; Weinstein, Stephanie J.; Chanock, Stephen J.; Jee, Sun Ha; Kweon, Sun-Seog; Vadaparampil, Susan; Harrison, Tabitha A.; Yamaji, Taiki; Keku, Temitope O.; Vymetalkova, Veronika; Arndt, Volker; Jia, Wei-Hua; Shu, Xiao-Ou; Lin, Yi; Ahn, Yoon-Ok; Stadler, Zsofia K.; Van Guelpen, Bethany; Ulrich, Cornelia M.; Platz, Elizabeth A.; Potter, John D.; Li, Christopher I.; Meester, Reinier; Moreno, Victor; Figueiredo, Jane C.; Casey, Graham; Lansdorp Vogelaar, Iris; Dunlop, Malcolm G.; Gruber, Stephen B.; Hayes, Richard B.; Pharoah, Paul D. P.; Houlston, Richard S.; Jarvik, Gail P.; Tomlinson, Ian P.; Zheng, Wei; Corley, Douglas A.; Peters, Ulrike; Hsu, Li Share Save
The impact of alterations in cancer driver genes and other potentially targetable mutations on progression and overall survival in patients with biliary tract cancer treated on the randomised phase III multicentre BILCAP clinical trial Crolley, V. E.; Guest, R.; Beggs, A. D.; Jaynes, E.; Thorn, S.; Herrero, J.; Tomlinson, I.; Valle, J. W.; Primrose, J. N.; Bridgewater, J. A. Share Save
Accounting for intensity variation in image analysis of large-scale multiplexed clinical trial datasets Frei, Anja L.; McGuigan, Anthony; Sinha, Ritik R. A. K.; Glaire, Mark A.; Jabbar, Faiz; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim J.; Saunders, Mark; Oein, Karin; Maka, Noori; Pezella, Francesco; Campo, Leticia; Hay, Jennifer; Edwards, Joanne; Sansom, Owen J.; Kelly, Caroline; Tomlinson, Ian; Kildal, Wanja; Kerr, Rachel S.; Kerr, David J.; Danielsen, Havard E.; Domingo, Enric; TransSCOT Consortium, David N.; Church, David N.; Koelzer, Viktor H. Share Save
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis Brown, Matthew; Leon, Alicia; Kedzierska, Katarzyna; Moore, Charlotte; Belnoue-Davis, Hayley L.; Flach, Susanne; Lydon, John P.; DeMayo, Francesco J.; Lewis, Annabelle; Bosse, Tjalling; Tomlinson, Ian; Church, David N. Share Save
Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair (vol 14, 3636, 2023) Sherwood, Kitty; Ward, Joseph C.; Soriano, Ignacio; Martin, Lynn; Campbell, Archie; Rahbari, Raheleh; Kafetzopoulos, Ioannis; Sproul, Duncan; Green, Andrew; Sampson, Julian R.; Donaldson, Alan; Ong, Kai-Ren; Heinimann, Karl; Nielsen, Maartje; Thomas, Huw; Latchford, Andrew; Palles, Claire; Tomlinson, Ian Share Save
Germline de novo mutations in families with Mendelian cancer syndromes caused by defects in DNA repair Sherwood, Kitty; Ward, Joseph C.; Soriano, Ignacio; Martin, Lynn; Campbell, Archie; Rahbari, Raheleh; Kafetzopoulos, Ioannis; Sproul, Duncan; Green, Andrew; Sampson, Julian R.; Donaldson, Alan; Ong, Kai-Ren; Heinimann, Karl; Nielsen, Maartje; Thomas, Huw; Latchford, Andrew; Palles, Claire; Tomlinson, Ian Share Save
Exploring the Complex Relationship between Gut Microbiota and Risk of Colorectal Neoplasia Using Bidirectional Mendelian Randomization Analysis Li, Wanxin; Zhou, Xuan; Yuan, Shuai; Wang, Lijuan; Yu, Lili; Sun, Jing; Chen, Jie; Xiao, Qian; Wan, Zhongxiao; Zheng, Ju-Sheng; Zhang, Cai-Xia; Larsson, Susanna C.; Farrington, Susan M.; Law, Philip; Houlston, Richard S.; Tomlinson, Ian; Ding, Ke-Feng; Dunlop, Malcolm G.; Theodoratou, Evropi; Li, Xue Share Save
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