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Disease coverage of human genome-wide association studies and pharmaceutical research and development Gordillo-Maranon, Maria; Schmidt, Amand F.; Warwick, Alasdair; Tomlinson, Chris; Ytsma, Cai; Engmann, Jorgen; Torralbo, Ana; Maclean, Rory; Sofat, Reecha; Langenberg, Claudia; Shah, Anoop D.; Denaxas, Spiros; Pirmohamed, Munir; Hemingway, Harry; Hingorani, Aroon D.; Finan, Chris Share Save
Communicating exploratory unsupervised machine learning analysis in age clustering for paediatric disease Spear, Joshua William; Pissaridou, Eleni; Bowyer, Stuart; Bryant, William A.; Key, Daniel; Booth, John; Spiridou, Anastasia; Denaxas, Spiros; Pope, Rebecca; Taylor, Andrew M.; Hemingway, Harry; Sebire, Neil J. Share Save
Proteomic signatures improve risk prediction for common and rare diseases Carrasco-Zanini, Julia; Pietzner, Maik; Davitte, Jonathan; Surendran, Praveen; Croteau-Chonka, Damien C.; Robins, Chloe; Torralbo, Ana; Tomlinson, Christopher; Gruenschlaeger, Florian; Fitzpatrick, Natalie; Ytsma, Cai; Kanno, Tokuwa; Gade, Stephan; Freitag, Daniel; Ziebell, Frederik; Haas, Simon; Denaxas, Spiros; Betts, Joanna C.; Wareham, Nicholas J.; Hemingway, Harry; Scott, Robert A.; Langenberg, Claudia Share Save
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Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats Steinfeldt, Jakob; Wild, Benjamin; Buergel, Thore; Pietzner, Maik; Upmeier zu Belzen, Julius; Vauvelle, Andre; Hegselmann, Stefan; Denaxas, Spiros; Hemingway, Harry; Langenberg, Claudia; Landmesser, Ulf; Deanfield, John; Eils, Roland Share Save
Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog Hingorani, Aroon D.; Gratton, Jasmine; Finan, Chris; Schmidt, A. Floriaan; Patel, Riyaz; Sofat, Reecha; Kuan, Valerie; Langenberg, Claudia; Hemingway, Harry; Morris, Joan K.; Wald, Nicholas J. Share Save
ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon Hartmann, Sylvia; Yasmeen, Summaira; Jacobs, Benjamin M.; Denaxas, Spiros; Pirmohamed, Munir; Gamazon, Eric R.; Caulfield, Mark J.; Hemingway, Harry; Pietzner, Maik; Langenberg, Claudia Share Save
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Identifying subtypes of heart failure from three electronic health record sources with machine learning: an external, prognostic, and genetic validation study Banerjee, Amitava; Dashtban, Ashkan; Chen, Suliang; Pasea, Laura; Thygesen, Johan H.; Fatemifar, Ghazaleh; Tyl, Benoit; Dyszynski, Tomasz; Asselbergs, Folkert W.; Lund, Lars H.; Lumbers, Tom; Denaxas, Spiros; Hemingway, Harry Share Save
Determining cardiovascular risk in patients with unattributed chest pain in UK primary care: an electronic health record study Jordan, Kelvin P.; Rathod-Mistry, Trishna; van der Windt, Danielle A.; Bailey, James; Chen, Ying; Clarson, Lorna; Denaxas, Spiros; Hayward, Richard A.; Hemingway, Harry; Kyriacou, Theocharis; Mamas, Mamas A. Share Save
Identifying subtypes of chronic kidney disease with machine learning: development, internal validation and prognostic validation using linked electronic health records in 350,067 individuals Dashtban, Ashkan; Mizani, Mehrdad A.; Pasea, Laura; Denaxas, Spiros; Corbett, Richard; Mamza, Jil B.; Gao, He; Morris, Tamsin; Hemingway, Harry; Banerjee, Amitava Share Save
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry Mueller, Stefanie H.; Lai, Alvina G.; Valkovskaya, Maria; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Qin; Dennis, Joe; Lush, Michael; Abu-Ful, Zomoruda; Ahearn, Thomas U.; Andrulis, Irene L.; Anton-Culver, Hoda; Antonenkova, Natalia N.; Arndt, Volker; Aronson, Kristan J.; Augustinsson, Annelie; Baert, Thais; Freeman, Laura E. Beane; Beckmann, Matthias W.; Behrens, Sabine; Benitez, Javier; Bermisheva, Marina; Blomqvist, Carl; Bogdanova, Natalia, V; Bojesen, Stig E.; Bonanni, Bernardo; Brenner, Hermann; Brucker, Sara Y.; Buys, Saundra S.; Castelao, Jose E.; Chan, Tsun L.; Chang-Claude, Jenny; Chanock, Stephen J.; Choi, Ji-Yeob; Chung, Wendy K.; Colonna, Sarah, V; Cornelissen, Sten; Couch, Fergus J.; Czene, Kamila; Daly, Mary B.; Devilee, Peter; Dork, Thilo; Dossus, Laure; Dwek, Miriam; Eccles, Diana M.; Ekici, Arif B.; Eliassen, A. Heather; Engel, Christoph; Evans, D. Gareth; Fasching, Peter A.; Fletcher, Olivia; Flyger, Henrik; Gago-Dominguez, Manuela; Gao, Yu-Tang; Garcia-Closas, Montserrat; Garcia-Saenz, Jose A.; Genkinger, Jeanine; Gentry-Maharaj, Aleksandra; Grassmann, Felix; Guenel, Pascal; Gundert, Melanie; Haeberle, Lothar; Hahnen, Eric; Haiman, Christopher A.; Hakansson, Niclas; Hall, Per; Harkness, Elaine F.; Harrington, Patricia A.; Hartikainen, Jaana M.; Hartman, Mikael; Hein, Alexander; Ho, Weang-Kee; Hooning, Maartje J.; Hoppe, Reiner; Hopper, John L.; Houlston, Richard S.; Howell, Anthony; Hunter, David J.; Huo, Dezheng; Investigators, Abctb; Ito, Hidemi; Iwasaki, Motoki; Jakubowska, Anna; Janni, Wolfgang; John, Esther M.; Jones, Michael E.; Jung, Audrey; Kaaks, Rudolf; Kang, Daehee; Khusnutdinova, Elza K.; Kim, Sung-Won; Kitahara, Cari M.; Koutros, Stella; Kraft, Peter; Kristensen, Vessela N.; Kubelka-Sabit, Katerina; Kurian, Allison W.; Kwong, Ava; Lacey, James, V; Lambrechts, Diether; Le Marchand, Loic; Li, Jingmei; Linet, Martha; Lo, Wing-Yee; Long, Jirong; Lophatananon, Artitaya; Mannermaa, Arto; Manoochehri, Mehdi; Margolin, Sara; Matsuo, Keitaro; Mavroudis, Dimitrios; Menon, Usha; Muir, Kenneth; Murphy, Rachel A.; Nevanlinna, Heli; Newman, William G.; Niederacher, Dieter; O'Brien, Katie M.; Obi, Nadia; Offit, Kenneth; Olopade, Olufunmilayo, I; Olshan, Andrew F.; Olsson, Hakan; Park, Sue K.; Patel, Alpa, V; Patel, Achal; Perou, Charles M.; Peto, Julian; Pharoah, Paul D. P.; Plaseska-Karanfilska, Dijana; Presneau, Nadege; Rack, Brigitte; Radice, Paolo; Ramachandran, Dhanya; Rashid, Muhammad U.; Rennert, Gad; Romero, Atocha; Ruddy, Kathryn J.; Ruebner, Matthias; Saloustros, Emmanouil; Sandler, Dale P.; Sawyer, Elinor J.; Schmidt, Marjanka K.; Schmutzler, Rita K.; Schneider, Michael O.; Scott, Christopher; Shah, Mitul; Sharma, Priyanka; Shen, Chen-Yang; Shu, Xiao-Ou; Simard, Jacques; Surowy, Harald; Tamimi, Rulla M.; Tapper, William J.; Taylor, Jack A.; Teo, Soo Hwang; Teras, Lauren R.; Toland, Amanda E.; Tollenaar, Rob A. E. M.; Torres, Diana; Torres-Mejia, Gabriela; Troester, Melissa A.; Truong, Therese; Vachon, Celine M.; Vijai, Joseph; Weinberg, Clarice R.; Wendt, Camilla; Winqvist, Robert; Wolk, Alicja; Wu, Anna H.; Yamaji, Taiki; Yang, Xiaohong R.; Yu, Jyh-Cherng; Zheng, Wei; Ziogas, Argyrios; Ziv, Elad; Dunning, Alison M.; Easton, Douglas F.; Hemingway, Harry; Hamann, Ute; Kuchenbaecker, Karoline B. Share Save
Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study Kuan, Valerie; Denaxas, Spiros; Patalay, Praveetha; Nitsch, Dorothea; Mathur, Rohini; Gonzalez-Izquierdo, Arturo; Sofat, Reecha; Partridge, Linda; Roberts, Amanda; Wong, Ian C. K.; Hingorani, Melanie; Chaturvedi, Nishi; Hemingway, Harry; Hingorani, Aroon; MMTRC Share Save
Using national electronic health records for pandemic preparedness: validation of a parsimonious model for predicting excess deaths among those with COVID-19-a data-driven retrospective cohort study Mizani, Mehrdad A.; Dashtban, Ashkan; Pasea, Laura; Lai, Alvina G.; Thygesen, Johan; Tomlinson, Chris; Handy, Alex; Mamza, Jil B.; Morris, Tamsin; Khalid, Sara; Zaccardi, Francesco; Macleod, Mary Joan; Torabi, Fatemeh; Canoy, Dexter; Akbari, Ashley; Berry, Colin; Bolton, Thomas; Nolan, John; Khunti, Kamlesh; Denaxas, Spiros; Hemingway, Harry; Sudlow, Cathie; Banerjee, Amitava; CVD COVID UK Consortium, C. V. D. C. O. V. I. D. U. K. Consortium Share Save
Rare and common genetic determinants of metabolic individuality and their effects on human health Surendran, Praveen; Stewart, Isobel D.; Yeung, Victoria P. W. Au; Pietzner, Maik; Raffler, Johannes; Worheide, Maria A.; Li, Chen; Smith, Rebecca F.; Wittemans, Laura B. L.; Bomba, Lorenzo; Menni, Cristina; Zierer, Jonas; Rossi, Niccolo; Sheridan, Patricia A.; Watkins, Nicholas A.; Mangino, Massimo; Hysi, Pirro G.; Di Angelantonio, Emanuele; Falchi, Mario; Spector, Tim D.; Soranzo, Nicole; Michelotti, Gregory A.; Arlt, Wiebke; Lotta, Luca A.; Denaxas, Spiros; Hemingway, Harry; Gamazon, Eric R.; Howson, Joanna M. M.; Wood, Angela M.; Danesh, John; Wareham, Nicholas J.; Kastenmueller, Gabi; Fauman, Eric B.; Suhre, Karsten; Butterworth, Adam S.; Langenberg, Claudia Share Save
CODE-EHR best-practice framework for the use of structured electronic health-care records in clinical research Kotecha, Dipak; Asselbergs, Folkert W.; Achenbach, Stephan; Anker, Stefan D.; Atar, Dan; Baigent, Colin; Banerjee, Amitava; Beger, Birgit; Brobert, Gunnar; Casadei, Barbara; Ceccarelli, Cinzia; Cowie, Martin R.; Crea, Filippo; Cronin, Maureen; Denaxas, Spiros; Derix, Andrea; Fitzsimons, Donna; Fredriksson, Martin; Gale, Chris P.; Gkoutos, Georgios, V; Goettsch, Wim; Hemingway, Harry; Ingvar, Martin; Jonas, Adrian; Kazmierski, Robert; Logstrup, Susanne; Lumbers, R. Thomas; Luescher, Thomas F.; McGreavy, Paul; Pina, Ileana L.; Roessig, Lothar; Steinbeisser, Carl; Sundgren, Mats; Tyl, Benoit; van Thiel, Ghislaine; van Bochove, Kees; Vardas, Panos E.; Villanueva, Tiago; Vrana, Marilena; Weber, Wim; Weidinger, Franz; Windecker, Stephan; Wood, Angela; Grobbee, Diederick E. Share Save
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