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Brian J.P. Huntly

university of cambridge

64H-index
331Paper Count
2.3WCitation Count
Published Papers 89
Publication Date
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The RNA helicase domain of NAT10 promotes the biogenesis of hypomodified ribosomes to enhance cancer cell proliferation
errNature Communications
IF15.7
err2026-08-08
err0
errOAAI
errMahmood H. Dalhat; Sharath Narayan; Maria Eleftheriou; James Russell; James Heslop; Hannah Serio; Khulood A. Alzahrani; Adam Suh; Ajay Edakkara; Sweta Raikundalia; Lea Landmann; Ryan Asby; Evangelia Stamou; Judith López; Yogeshkumar Malam; Demetrios Aspris; Emmely A. Patrasso; Stephanie Mou; George Giotopoulos; Walid T. Khaled; Brian J. P. Huntly; Fotios Sampaziotis; Konstantinos Tzelepis; Daniel Arango
errShare
errSave
Prognostic impact of myelodysplasia-related gene mutations in FLT3-ITD-mutated acute myeloid leukemia
errLeukemia
IF13.4
err2026-02-09
err0
errOAAI
errRabea Mecklenbrauck; Angela Villaverde Ramiro; Eric Sträng; Razif Gabdoulline; Javier Martinez Elicegui; Marta Sobas; Lisa Pleyer; Amin Turki; Maria Teresa Voso; Axel Benner; Alberto Hernández-Sánchez; Jesse M. Tettero; Laura Tur Gimenez; Klaus H. Metzeler; Guadalupe Oñate; Sören Lehmann; Brian JP Huntly; Ian Thomas; Felicitas R. Thol; Florian H. Heidel; Peter JM Valk; Konstanze Döhner; Torsten Haferlach; Kenneth I. Mills; Hartmut Döhner; Gastone Castellani; Gert J. Ossenkoppele; Jesus María Hernández-Rivas; Lars Bullinger; Michael Heuser
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errSave
Unravelling co-mutational patterns with prognostic implications in NPM1 mutated adult acute myeloid leukemia – a HARMONY study
errLeukemia
IF13.4
err2026-01-14
err0
errOAAI
errAlberto Hernández-Sánchez; Ángela Villaverde Ramiro; Eric Sträng; Amin T. Turki; María Abáigar; Jurjen Versluis; Ian Thomas; Marta Sobas; Javier Martínez Elicegui; Gastone Castellani; Axel Benner; Raúl Azibeiro; Jesse M. Tettero; Rabea Mecklenbrauck; Joaquín Martínez-López; Marta Pratcorona; Ken I. Mills; Guillermo Sanz; Maria Teresa Voso; Lehmann Sören; Christoph Röllig; Christian Thiede; Klaus H. Metzeler; Konstanze Döhner; Michael Heuser; Torsten Haferlach; Peter JM Valk; Nigel Russell; Jesús María Hernández-Rivas; Brian Huntly; Gert Ossenkoppele; Hartmut Döhner; Lars Bullinger
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errSave
Identification of epigenetic regulators of fibrotic transformation in cardiac fibroblasts through bulk and single-cell CRISPR screens
errNature Communications
IF15.7
err2025-11-26
err0
errOAAI
errLaura Pilar Aguado-Alvaro; Nerea Garitano; Wolfgang Esser-Skala; Judy Sayers; Cynthia del Valle; Daniel Alameda; Julen Mendieta-Esteban; Maria Erendira Calleja-Cervantes; Ainhoa Goñi-Salaverri; Jon Zazpe; Anna Rosaria de Vito; Francesco Marchese; Diego Alignani; Juliana Cudini; Torsten Gross; Gregorio Rábago; Nisha Narayan; Laura Martinez; Sonia Martinez; Brian Huntly; Paul Riley; Arantxa Gonzalez; Jake P. Taylor-King; Nikolaus Fortelny; Beatriz Pelacho; David Lara-Astiaso
errShare
errSave
Post-transcriptional depletion of ribosome biogenesis factors engenders therapeutic vulnerabilities in NPM1-mutant AML
errBlood
IF23.1
err2025-06-27
err0
errOAAI
errAristi Damaskou; Rachael Wilson; Malgorzata Gozdecka; George Giotopoulos; Ryan Asby; Maria Eleftheriou; Muxin Gu; Christian Récher; Véronique De Mas; Francois Vergez; Ambrine Sahal; Binje Vick; Evangelia K. Papachristou; Ashley Sawle; Eliza Yankova; Monika Dudek; Xiaoxuan Liu; James Russell; Justyna Rak; Christine Hilcenko; Clive D’ Santos; Irmela Jeremias; Jean-Emmanuel Sarry; Konstantinos Tzelepis; Brian J. P. Huntly; Alan J. Warren; Omid Tavana; George S. Vassiliou
errShare
errSave
Epigenetic Dysregulation in Acute Myeloid Leukemia
errSeminars in Hematology
IF4.1
err2025-06-19
err0
errOAAI
errJens Schrezenmeier; B.J.P. Huntly
errShare
errSave
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
errNATURE COMMUNICATIONS
IF15.7
err2025-05-20
err0
errOAAI
errGarcia-Gimenez, Alicia; Ditcham, Jonathan E.; Azazi, Dhoyazan M. A.; Giotopoulos, George; Asby, Ryan; Meduri, Eshwar; Bagri, Jaana; Sakakini, Nathalie; Lopez, Cecile K.; Narayan, Nisha; Beinortas, Tumas; Agrawal-Singh, Shuchi; Fung, Kent; O'Connor, David; Mansour, Marc R.; Alabed, Husam B. R.; Jenkins, Benjamin; Koulman, Albert; Murphy, Michael P.; Horton, Sarah J.; Huntly, Brian J. P.
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errSave
Treatment of acute myeloid leukemia models by targeting a cell surface RNA-binding protein
errNATURE BIOTECHNOLOGY
IF41.7
err2025-04-23
err0
errOAAI
errGeorge, Benson M.; Eleftheriou, Maria; Yankova, Eliza; Perr, Jonathan; Chai, Peiyuan; Nestola, Gianluca; Almahayni, Karim; Evans, Sian; Damaskou, Aristi; Hemberger, Helena; Lebedenko, Charlotta G.; Rak, Justyna; Yu, Qi; Bapcum, Ece; Russell, James; Bagri, Jaana; Volk, Regan F.; Spiekermann, Malte; Stone, Richard M.; Giotopoulos, George; Huntly, Brian J. P.; Baxter, Joanna; Camargo, Fernando; Liu, Jie; Zaro, Balyn W.; Vassiliou, George S.; Moeckl, Leonhard; de la Rosa, Jorge; Tzelepis, Konstantinos
errShare
errSave
Timing and trajectory of BCR::ABL1-driven chronic myeloid leukaemia
errNATURE
IF48.5
err2025-04-09
err0
errOAAI
errKamizela, Aleksandra E.; Leongamornlert, Daniel; Williams, Nicholas; Wang, Xin; Nyamondo, Kudzai; Dawson, Kevin; Chapman, Michael Spencer; Guo, Jing; Lee, Joe; Mane, Karim; Milne, Kate; Green, Anthony R.; Chevassut, Timothy; Campbell, Peter J.; Ellinor, Patrick T.; Huntly, Brian J. P.; Baxter, E. Joanna; Nangalia, Jyoti
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errSave
Interim Analysis of Promise, a Clinical Study Combining the BET Inhibitor OPN-2853 with Ruxolitinib in Patients with Advanced Myelofibrosis Experiencing an Inadequate Response to Ruxolitinib
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMead, Adam J.; Huntly, Brian J. P.; Psaila, Bethan; Harrison, Claire; Boucher, Rebecca; Wang, Jiayi; Collings, Rebecca; Nagy, Zsofia; Record, Rebecca
errShare
errSave
Acute Resistance to BET Inhibitors Remodels Compensatory Transcriptional Programs Via p300 Co-Activation
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errShah, Viral; Giotopoulos, George; Osaki, Hikari; Meyerhoefer, Markus; Meduri, Eshwar; Gallego-Crespo, Aaron; Behrendt, Malte Andreas; Saura-Panella, Maria; Schubert, Benedict; Yun, Haiyang; Horton, Sarah J.; Singh, Shuchi Agrawal; Haehnel, Patricia S.; Basheer, Faisal; Lugo, Dave; Kuehn, Michael; Guezguez, Borhane; Theobald, Matthias; Kindler, Thomas; Gallipoli, Paolo; Yeh, Paul; Dawson, Mark A.; Prinjha, Rab; Huntly, Brian J. P.; Sasca, Daniel
errShare
errSave
The Prognostic Impact of Myelodysplasia-Related Gene Mutations in Acute Myeloid Leukemia with FLT3-ITD Mutations
errBLOOD
IF23.1
err2024-11-05
err0
PREAI
errMecklenbrauck, Rabea; Ramiro, Angela Villaverde; Straeng, Eric; Gabdoulline, Razif; Elicegui, Javier Martinez; Sobas, Marta; Pleyer, Lisa; Voso, Maria Teresa; Benner, Axel; Sanchez, Alberto Hernandez; Tettero, Jesse M.; Tur, Laura; Metzeler, Klaus H.; Onate, Guadalupe; Lehmann, Soren; Huntly, Brian J. P.; Thomas, Ian; Thol, Felicitas R.; Heidel, Florian; Valk, Peter J. M.; Doehner, Konstanze; Haferlach, Torsten; Mills, Ken, I; Doehner, Hartmut; Castellani, Gastone; Ossenkoppele, Gert; Rivas, Jesus Maria Hernandez; Bullinger, Lars; Heuser, Michael
errShare
errSave
Novel immunotherapeutics against LGR5 to target multiple cancer types (vol 16, pg 2233, 2024)
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-09-25
err1
errOAAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Fard, Amir Rafati; Ghodsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
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errSave
Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression
errBLOOD ADVANCES
IF7.1
err2024-09-25
err2
errOAAI
errMinciacchi, Valentina R.; Karantanou, Christina; Bravo, Jimena; Pereira, Raquel S.; Zanetti, Costanza; Krack, Theresa; Kumar, Rahul; Bankov, Katrin; Hartmann, Sylvia; Huntly, Brian J. P.; Meduri, Eshwar; Ruf, Wolfram; Krause, Daniela S.
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errSave
Impact of BCR::ABL1 single nucleotide variants on asciminib efficacy
errLEUKEMIA
IF13.4
err2024-09-17
err0
errOAAI
errInnes, Andrew J.; Hayden, Chloe; Orovboni, Victoria; Claudiani, Simone; Fernando, Fiona; Khan, Afzal; Rees, David; Byrne, Jennifer; Gallipoli, Paolo; Francis, Sebastian; Copland, Mhairi; Horne, Gillian; Raghavan, Manoj; Arnold, Claire; Collins, Angela; Cranfield, Tanya; Cunningham, Nicholas; Danga, Akila; Forsyth, Peter; Frewin, Rebecca; Garland, Paula; Hannah, Guy; Avenoso, Daniele; Hassan, Sandra; Huntly, Brian J. P.; Husain, Jissan; Makkuni, Sudhakaran; Rothwell, Kate; Khorashad, Jamshid; Apperley, Jane F.; Milojkovic, Dragana
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errSave
Novel immunotherapeutics against LGR5 to target multiple cancer types
errEMBO MOLECULAR MEDICINE
IF8.3
err2024-08-21
err1
PREAI
errChen, Hung-Chang; Mueller, Nico; Stott, Katherine; Kapeni, Chrysa; Rivers, Eilidh; Sauer, Carolin M.; Beke, Flavio; Walsh, Stephen J.; Ashman, Nicola; O'Brien, Louise; Rafati Fard, Amir; Godsinia, Arman; Li, Changtai; Joud, Fadwa; Giger, Olivier; Zlobec, Inti; Olan, Ioana; Aitken, Sarah J.; Hoare, Matthew; Mair, Richard; Serrao, Eva; Brenton, James D.; Garcia-Gimenez, Alicia; Richardson, Simon E.; Huntly, Brian; Spring, David R.; Skjoedt, Mikkel-Ole; Skjodt, Karsten; de la Roche, Marc; de la Roche, Maike
errShare
errSave
Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study
errLEUKEMIA
IF13.4
err2024-07-04
err3
errOAAI
errHernandez-Sanchez, Alberto; Gonzalez, Teresa; Sobas, Marta; Straeng, Eric; Castellani, Gastone; Abaigar, Maria; Valk, Peter J. M.; Ramiro, Angela Villaverde; Benner, Axel; Metzeler, Klaus H.; Azibeiro, Raul; Tettero, Jesse M.; Martinez-Lopez, Joaquin; Pratcorona, Marta; Elicegui, Javier Martinez; Mills, Ken I.; Thiede, Christian; Sanz, Guillermo; Doehner, Konstanze; Heuser, Michael; Haferlach, Torsten; Turki, Amin T.; Reinhardt, Dirk; Schulze-Rath, Renate; Barbus, Martje; Hernandez-Rivas, Jesus Maria; Huntly, Brian; Ossenkoppele, Gert; Doehner, Hartmut; Bullinger, Lars
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errSave
Integrated functional genomic screening to bypass TKI resistance in chronic myeloid leukemia
errCELL REPORTS MEDICINE
IF10.6
err2024-05-01
err0
errOAAI
errBeinortas, Tumas; Huntly, Brian J. P.
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errSave
Precision hematology: Navigating the evolution of diagnostic classifications in the era of globalized medicine
errHEMASPHERE
IF14.6
err2024-04-04
err0
errOAAI
errMacintyre, Elizabeth; Doehner, Konstanze; Gronbaek, Kirsten; Dreyling, Martin; Huntly, Brian; Almeida, Antonio; Gribben, John
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errSave
Genetic or pharmacological inactivation of CREBBP sensitizes B-cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errGimenez, Alicia Garcia; Ditcham, Jonathan; Azazi, Dhoyazan M.; Meduri, Eshwar; Asby, Ryan; Sakakini, Nathalie; Lopez, Cecile K.; Narayan, Nisha; Bagri, Jaana; Beinortas, Tumas; Singh, Shuchi Agrawal; Giotopoulos, George; Murphy, Michael P.; Horton, Sarah J.; Huntly, Brian J.; Richardson, Simon E.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
M
Michael R. Stratton
H-index: 179 · Papers: 644
P
Pier Paolo Pandolfi
H-index: 160 · Papers: 818
P
Peter J. Campbell
H-index: 159 · Papers: 747
H
Hartmut Döhner
H-index: 146 · Papers: 1.4K
M
Michael P. Murphy
H-index: 142 · Papers: 777
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