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Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib (vol 14, 4444, 2023 Coombes, R. C.; Howell, Sacha; Lord, Simon R.; Kenny, Laura; Mansi, Janine; Mitri, Zahi; Chap, Linnea I.; Richards, Paul; Gradishar, William; Sardesai, Sagar; Melear, Jason; O'Shaughnessy, Joyce; Ward, Patrick; Chalasani, Pavani; Arkenau, Tobias; Baird, Richard D.; Jeselsohn, Rinath; Clack, Glen; Bahl, Ashwani; Mcintosh, Stuart; Krebs, Matthew G. Share Save
Induction of the TEAD Coactivator VGLL1 by Estrogen Receptor-Targeted Therapy Drives Resistance in Breast Cancer Gemma, Carolina; Lai, Chun-Fui; Singh, Anup K.; Belfiore, Antonino; Portman, Neil; Milioli, Heloisa Z.; Periyasamy, Manikandan; Raafat, Sara; Nicholls, Alyssa J.; Davies, Claire M.; Patel, Naina R.; Simmons, Georgia M.; Fan, Hailing; Nguyen, Van T. M.; Magnani, Luca; Rakha, Emad; Martin, Lesley-Ann; Lim, Elgene; Coombes, R. Charles; Pruneri, Giancarlo; Buluwela, Laki; Ali, Simak Share Save
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Performance of a novel spectroscopy-based tool for adjuvant therapy decision-making in hormone receptor-positive breast cancer: a validation study (Jan, 10.1007/s10549-023-07229-y, 2024) Coombes, R. Charles; Angelou, Christina; Al-Khalili, Zamzam; Hart, William; Francescatti, Darius; Wright, Nicholas; Ellis, Ian; Green, Andrew; Rakha, Emad; Shousha, Sami; Amrania, Hemmel; Phillips, Chris C.; Palmieri, Carlo Share Save
Extracellular vesicles as a promising source of lipid biomarkers for breast cancer detection in blood plasma Dorado, Erika; Doria, Maria Luisa; Nagelkerke, Anika; Mckenzie, James S.; Maneta-Stavrakaki, Stefania; Whittaker, Thomas E.; Nicholson, Jeremy K.; Coombes, Raoul Charles; Stevens, Molly M.; Takats, Zoltan Share Save
Performance of a novel spectroscopy-based tool for adjuvant therapy decision-making in hormone receptor-positive breast cancer: a validation study Coombes, Charles; Angelou, Christina; Al-Khalili, Zamzam; Hart, William; Francescatti, Darius; Wright, Nicholas; Ellis, Ian; Green, Andrew; Rakha, Emad; Shousha, Sami; Amrania, Hemmel; Phillips, Chris C.; Palmieri, Carlo Share Save
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Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib Coombes, R. Charles; Howell, Sacha; Lord, Simon R.; Kenny, Laura; Mansi, Janine; Mitri, Zahi; Palmieri, Carlo; Chap, Linnea I.; Richards, Paul; Gradishar, William; Sardesai, Sagar; Melear, Jason; O'Shaughnessy, Joyce; Ward, Patrick; Chalasani, Pavani; Arkenau, Tobias; Baird, Richard D.; Jeselsohn, Rinath; Ali, Simak; Clack, Glen; Bahl, Ashwani; McIntosh, Stuart; Krebs, Matthew G. Share Save
A Rapid, Shallow Whole Genome Sequencing Workflow Applicable to Limiting Amounts of Cell-Free DNA Allsopp, Rebecca C.; Page, Karen; Ambasager, Bana; Wadsley, Marc K.; Acheampong, Emmanuel; Ntereke, Tumisang P.; Guo, Qi; Lall, Gurdeep Matharu; Gleason, Kelly L. T.; Wren, Evie; Nteliopoulos, Georgios; Rushton, Amelia J.; Coombes, R. Charles; Shaw, Jacqueline A. Share Save
Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer (vol 13, 3246, 2022) Coombes, R. C.; Badman, P. D.; Lozano-Kuehne, J. P.; Liu, X.; Macpherson, I. R.; Zubairi, I.; Baird, R. D.; Rosenfeld, N.; Garcia-Corbacho, J.; Cresti, N.; Plummer, R.; Armstrong, A.; Allerton, R.; Landers, D.; Nicholas, H.; McLellan, L.; Lim, A.; Mouliere, F.; Pardo, O. E.; Ferguson, V.; Seckl, M. J. Share Save
Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer Harrod, Alison; Lai, Chun-Fui; Goldsbrough, Isabella; Simmons, Georgia M.; Oppermans, Natasha; Santos, Daniela B.; Gyorffy, Balazs; Allsopp, Rebecca C.; Toghill, Bradley J.; Balachandran, Kirsty; Lawson, Mandy; Morrow, Christopher J.; Surakala, Manasa; Carnevalli, Larissa S.; Zhang, Pei; Guttery, David S.; Shaw, Jacqueline A.; Coombes, R. Charles; Buluwela, Lakjaya; Ali, Simak Share Save
Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer Fernandez-Garcia, Daniel; Nteliopoulos, Georgios; Hastings, Robert K.; Rushton, Amelia; Page, Karen; Allsopp, Rebecca C.; Ambasager, Bana; Gleason, Kelly; Guttery, David S.; Ali, Simak; Coombes, R. Charles; Shaw, Jacqueline A. Share Save
Results of the phase IIa RADICAL trial of the FGFR inhibitor AZD4547 in endocrine resistant breast cancer Coombes, R. C.; Badman, P. D.; Lozano-Kuehne, J. P.; Liu, X.; Macpherson, I. R.; Zubairi, I; Baird, R. D.; Rosenfeld, N.; Garcia-Corbacho, J.; Cresti, N.; Plummer, R.; Armstrong, A.; Allerton, R.; Landers, D.; Nicholas, H.; McLellan, L.; Lim, A.; Mouliere, F.; Pardo, O. E.; Seckl, M. J. Share Save
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Study of samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in combination with fulvestrant in patients with advanced hormone receptor positive HER2 negative breast cancer (HR plus BC) Coombes, Charles; Howell, Sasha J.; Krebs, Matthew G.; Lord, Simon; Kenny, Laura M.; Bahl, Ash; Clack, Glen; Ainscow, Edward; Dickinson, Paul A.; Fostea, Raluca; Mansi, Janine; Palmieri, Carlo; Bertelli, Gianflippo; Jeselsohn, Rinath; Mitri, Zahi; Gradishar, William J.; Sardesai, Sagar; O'Shaughnessy, Joyce; Ward, Patrick; Chalasani, Pavani; Lehnert, Manfred; Ali, Simak; McIntosh, Stuart Share Save
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A clinical study of samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in patients with advanced triple negative breast cancer (TNBC) Howell, Sacha J.; Kenny, Laura M.; Lord, Simon; Krebs, Matthew G.; Arkenau, Tobias; Baird, Richard; MacPherson, Iain R.; Bahl, Ash; Clack, Glen; Ainscow, Edward; Barrett, Anthony G. M.; Dickinson, Paul A.; Fuchter, Matthew J.; Lehnert, Manfred; Ali, Simak; McIntosh, Stuart; Coombes, Charles Share Save
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