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Robert E. MacLaren

Oxford University Hospitals NHS Foundation Trust

67H-index
652Paper Count
1.9WCitation Count
Published Papers 181
Publication Date
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Progress in gene therapy for RPGR-associated X-linked retinitis pigmentosa
errExpert Opinion on Biological Therapy
IF4
err2026-09-27
err0
errOAAI
errMaram E. A. Abdalla Elsayed; Robert E. MacLaren
errShare
errSave
Quantification of Ocular Gene Therapy-Related Inflammation Using the VRMACS Grading System
errOphthalmology Science
IF4.6
err2026-08-01
err0
PREAI
errElsayed, Maram E. A. Abdalla; MacLaren, Robert E.
errShare
errSave
Efficacy of anti-VEGF single-chain variable fragment AAV-based gene therapy in a laser-induced choroidal neovascularisation mouse model
errMOLECULAR THERAPY ADVANCES
IF0
err2026-05-01
err0
PREAI
errSalman, Ahmed; Griffiths, Helen; Garba, Kamaluddeen; Lynn, Savannah A.; Cree, Angela J.; Szczepan, Manon; Jashal, Charnitkaur B.; Chozhavel, T. M. Rajanathan; Rao, Poornima; Modi, Kush; MacLaren, Robert E.; Yuen, Ho Ming; Lotery, Andrew J.
errShare
errSave
Ophthalmic manifestations of mitochondrial disorders
errProgress in Retinal and Eye Research
IF14.7
err2026-04-03
err0
PREAI
errMegan F. Baxter; Grace A. Borchert; Emma L. Blakely; Claire W. Ruan; Robert E. MacLaren; Robert McFarland; Robert W. Taylor
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errSave
Precision Is Not Enough: When Tools Outpace Translation in Ocular Gene Therapy
errGenes
IF2.8
err2026-02-27
err0
errOAAI
errMaram E. A. Abdalla Elsayed; Robert E. MacLaren
errShare
errSave
IMPG2-associated retinal dystrophy with a novel missense variant and therapeutic options via adenine base editing
errOphthalmic Genetics
IF1
err2026-01-01
err0
PREAI
errAbdalla Elsayed, Maram E. A.; Barone, Vincenzo; Kaukonen, Maria; Raybould, Matthew I. J.; MacLaren, Robert E.
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errSave
Expanding the Genetic Spectrum in IMPG1 and IMPG2 Retinopathy
errGenes 2025, Vol. 16, Page 1474
IF2.8
err2025-12-09
err0
errOAAI
errSaoud Al-Khuzaei; Ahmed K. Shalaby; Jing Yu; Morag Shanks; Penny Clouston; Robert E. MacLaren; Stephanie Halford; Samantha R. De Silva; Susan M. Downes
errShare
errSave
Central Retinal Sensitivity Decline in RPGR-related Retinal Phenotypes
errAmerican Journal of Ophthalmology
IF4.2
err2025-11-12
err0
errOAAI
errAmandeep Singh Josan; Laura J Taylor; Shabnam Raji; Jasmina Cehajic-Kapetanovic; Robert E MacLaren
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errSave
Gene Therapy Strategies for the Treatment of Bestrophinopathies
errInternational Journal of Molecular Sciences 2025, Vol. 26, Page 9421
IF4.9
err2025-09-28
err0
errOAAI
errSilja B. Haldrup; Michelle E. McClements; Jasmina Cehajic-Kapetanovic; Thomas J. Corydon; Robert E. MacLaren
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errSave
Multimodal imaging and electrophysiological features in bradyopsia associated with homozygous variants (c.895T>C) in Regulator of G-protein Signaling 9 (RGS9)
errOPHTHALMIC GENETICS
IF0
err2025-09-01
err0
PREAI
errBorchert, Grace A.; Heath Jeffery, Rachael C.; Sperring, Sian; Shanks, Morag; Whitfield, Jennifer; Clouston, Penny; Lamey, Tina; Thompson, Jennifer A.; Roshandel, Danial; Chelva, Enid S.; Cottriall, Charles; Xue, Kanmin; De Silva, Samantha R.; Cehajic-Kapetanovic, Jasmina; MacLaren, Robert E.; McLaren, Terri; Nemeth, Andrea H.; Downes, Susan M.; Chen, Fred K.
errShare
errSave
Genotype–Phenotype Correlations in PRPH2 Retinopathies: A Comprehensive Analysis of 36 Patients from the Oxford Eye Hospital, UK
errGenes 2025, Vol. 16, Page 1016
IF2.8
err2025-08-28
err0
errOAAI
errSaoud Al-Khuzaei; Mital Shah; Arun Reginald; Edna Baba; Morag Shanks; Penny Clouston; Robert E. MacLaren; Stephanie Halford; Samantha R. De Silva; Susan M. Downes
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errSave
Exploring standard and low luminance visual acuity and the Moorfields Acuity Chart as outcome measures in inherited retinal disease
errOphthalmic and Physiological Optics
IF2.4
err2025-06-02
err0
errOAAI
errLaura J. Taylor; Amandeep S. Josan; Robert E. MacLaren
errShare
errSave
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy
errPROGRESS IN RETINAL AND EYE RESEARCH
IF14.7
err2025-05-01
err1
errOAAI
errPurdy, Ryan; John, Molly; Bray, Alissa; Clare, Alison J.; Copland, David A.; Chan, Ying Kai; Henderson, Robert H.; Nerinckx, Fanny; Leroy, Bart P.; Yang, Paul; Pennesi, Mark E.; Maclaren, Robert E.; Fischer, M. Dominik; Dick, Andrew D.
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errSave
Gene therapy for choroideremia: progress, potential and pitfalls
errEXPERT OPINION ON BIOLOGICAL THERAPY
IF4
err2025-02-23
err0
PREAI
errAbdalla Elsayed, Maram E. A.; Cehajic-Kepetanovic, Jasmina; Maclaren, Robert E.
errShare
errSave
Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration
errCOMMUNICATIONS BIOLOGY
IF5.1
err2025-02-08
err0
errOAAI
errFry, Lewis E.; Major, Lauren; Salman, Ahmed; Mcdermott, Lucy A.; Yang, Jun; King, Andrew J.; Mcclements, Michelle E.; Maclaren, Robert E.
errShare
errSave
XOLARIS: A 24-Month, Prospective, Natural History Study of 201 Participants with Retinitis Pigmentosa GTPase Regulator-Associated X-Linked Retinitis Pigmentosa
errOPHTHALMOLOGY SCIENCE
IF4.6
err2025-01-01
err0
PREAI
errMacLaren, Robert E.; Duncan, Jacque L.; Fischer, M. Dominik; Lam, Byron L.; Meunier, Isabelle; Pennesi, Mark E.; Sankila, Eeva-Marja K.; Gow, James A.; Li, Jiang; Tsang, So-Fai
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errSave
Ranked Importance of Visual Function Outcome Measures in Choroideremia Clinical Trials
errINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
err2024-11-27
err0
errOAAI
errJosan, Amandeep Singh; Taylor, Laura Jayne; Xue, Kanmin; Cehajic-Kapetanovic, Jasmina; Maclaren, Robert Edward
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errSave
Assessment of Visual Function with Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa in the Randomized XIRIUS Phase 2/3 Study
errOPHTHALMOLOGY
IF9.5
err2024-09-01
err5
PREAI
errLam, Byron L.; Pennesi, Mark E.; Kay, Christine N.; Panda, Sushil; Gow, James A.; Zhao, Guolin; MacLaren, Robert E.
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errSave
Single-cell transcriptomic analysis of retinal immune regulation and blood-retinal barrier function during experimental autoimmune uveitis
errSCIENTIFIC REPORTS
IF3.9
err2024-08-28
err5
errOAAI
errQuinn, Joel; Salman, Ahmed; Paluch, Christopher; Jackson-Wood, Matthew; McClements, Michelle E.; Luo, Jian; Davis, Simon J.; Cornall, Richard J.; MacLaren, Robert E.; Dendrou, Calliope A.; Xue, Kanmin
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errSave
Longitudinal assessment of female carriers of choroideremia using multimodal retinal imaging
errBRITISH JOURNAL OF OPHTHALMOLOGY
IF3.5
err2024-08-09
err0
errOAAI
errGocuk, Sena A.; Ayton, Lauren N.; Edwards, Thomas L.; McGuinness, Myra B.; Maclaren, Robert E.; Taylor, Laura J.; Jolly, Jasleen K.
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errSave

Research Directions

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Co-authors
Cooperation Journals
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H
Hugh S. Markus
H-index: 138 · Papers: 873
P
Patrick F. Chinnery
H-index: 128 · Papers: 939
R
Richard C. Trembath
H-index: 118 · Papers: 586
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