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D

David L. Spector

cold spring harbor

92H-index
332Paper Count
3.9WCitation Count
Published Papers 101
Publication Date
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A dependency map enhanced with next-generation 3D cancer models
errNature
IF48.5
err2026-08-05
err0
errOAAI
errJames V. Neiswender; Samuel Maffa; Lisa Brenan; Dina ElHarouni; Yejie Yun; Isabella Boyle; Kirsty Wienand; Haider Inam; Tate Bertea; Ashley Anderson; Megan Wong; Matias Enriquez; Evan Lenz; Beatriz Villafranca; Nora Shanks; Mary Hager; Nia Lloyd; Hannah Shadmany; Sarah J. Wie; Harry Liang; Konnor Yunghans; Xiaomeng Zhang; Lauren Golden; Hannah Harris; Serena Day; Philip Montgomery; Samantha Stokes; Ross M. Giglio; Cynthia Hajal; James R. Whittle; Guadalupe Garcia; Caitlin E. Mills; Mehdi Touat; Kristine Pelton; Hongyu Li; Prem Sai Prabhakar; Sonja Herter; Zoe Hoffmann Kamrat; Dan Gui; Julien Dilly; Chen Khuan Wong; Jimmy A. Guo; Sangita Pal; Yossef Baidi; Ryan Johnston; Daniel D. Brown; Sonam Bhatia; Peter S. Winter; Srivatsan Raghavan; Rameen Beroukhim; Eva Colas; David L. Spector; Adam J. Bass; Peter K. Sorger; Yu Chen; Sarah J. Hill; Steffi Oesterreich; Adrian V. Lee; Himisha Beltran; Jesse S. Boehm; Yuen-Yi Tseng; David E. Root; William C. Hahn; Andrew J. Aguirre; Catarina D. Campbell; Keith L. Ligon; Joshua M. Dempster; Tsukasa Shibue; Francisca Vazquez
errShare
errSave
A compendium of next-generation patient-derived models for diverse cancers
errNature
IF48.5
err2026-08-05
err0
errOAAI
errDina ElHarouni; Mushriq Al-Jazrawe; Seongmin Choi; Merve Dede; Toshinori Hinoue; Sean A. Misek; Heeju Noh; Luca Zanella; Yuen-Yi Tseng; Hayley E. Francies; Dennis Plenker; Cindy W. Kyi; Julyann Perez-Mayoral; Megan J. Stine; Eva Tonsing-Carter; Rachana Agarwal; Jean Claude Zenklusen; James M. Clinton; Jennifer M. Shelton; Timothy R. Chu; William F. Hooper; Xavi Loinaz; Paula Keskula; Jordan Tagle; Peyton C. Kuhlers; Bahar Tercan; Sylvia F. Boj; Alessandro Vasciaveo; Lorenzo Tomassoni; James M. Crawford; Shawna Walsh; Claire Sinai; Sonam Bhatia; Priya Sridevi; Hardik Patel; Maria Antonietta Cerone; Kyle Ellrott; Calvin J. Kuo; Olivier Elemento; Semir Beyaz; Vincenzo Corbo; David L. Spector; Rameen Beroukhim; Martin L. Ferguson; Andrew D. Cherniack; Peter W. Laird; Nicolas Robine; Andrew McPherson; Katherine A. Hoadley; Mathew J. Garnett; David A. Tuveson; Andrea Califano; Paul T. Spellman; Keith L. Ligon; Daniela S. Gerhard; Louis M. Staudt; Jesse S. Boehm
errShare
errSave
Safety and Effectiveness of Metabolic and Bariatric Procedures in Heart Failure: A Multicenter Retrospective Cohort Study
errObesity
IF4.7
err2026-03-19
err0
PREAI
errJohn W. Ostrominski; Madeleine Schwede; Jenna Lodi; Pichamol Jirapinyo; David Spector; Eric G. Sheu; Elke Platz
errShare
errSave
A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear lamin B1 region
errCellular and Molecular Life Sciences
IF6.2
err2026-01-03
err0
errOAAI
errGayan I. Balasooriya; Payal Naik; Tse-Luen Wee; David L. Spector
errShare
errSave
Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumors
errNature Communications
IF15.7
err2025-10-15
err0
errOAAI
errMichael F. Ciccone; Dhivyaa Anandan; Deeptiman Chatterjee; Chen Chen; Marygrace C. Trousdell; Rebecca Anderson; Steven M. Lewis; Mackenzie K. Callaway; Chris Z. Zhao; Amritha Varshini Hanasoge Somasundara; Suzanne Russo; Shih-Ting Yang; Yixin Zhao; Julie Ostrander; John E. Wilkinson; William C. K. Pomerantz; Adam Siepel; David L. Spector; Jessica Tollkuhn; Camila O. dos Santos
errShare
errSave
Longitudinal tracking of MALAT1 level over a breast cancer patient's course of treatment and disease
errMolecular Therapy Oncology
IF5.3
err2025-10-01
err0
errOAAI
errAggarwal, Disha; Wee, Tse-Luen; Satpathy, Shuchismita; Russo, Suzanne; Spector, David L.
errShare
errSave
The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade
errNATURE METABOLISM
IF20.8
err2024-08-27
err1
PREAI
errQiu, Yijian; Stamatatos, Olivia T.; Hu, Qingting; Swain, Jed Ruiter; Russo, Suzanne; Sann, Ava; Costa, Ana S. H.; Violante, Sara; Spector, David L.; Cross, Justin R.; Lukey, Michael J.
errShare
errSave
MARK2/MARK3 Kinases Are Catalytic Codependencies of YAP/TAZ in Human Cancer
errCANCER DISCOVERY
IF33.3
err2024-07-25
err0
errOAAI
errKlingbeil, Olaf; Skopelitis, Damianos; Tonelli, Claudia; Yoshimoto, Toyoki; Alpsoy, Aktan; Panepinto, Maria C.; Minicozzi, Francesca; Merrill, Joseph R.; Cafiero, Amanda M.; Aggarwal, Disha; Russo, Suzanne; Ha, Taehoon; Demerdash, Osama E.; Wee, Tse-Luen; Spector, David L.; Lyons, Scott K.; Tuveson, David A.; Cifani, Paolo; Vakoc, Christopher R.
errShare
errSave
Chronic stress causes metastasis via neutrophil-mediated changes to the microenvironment
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errHe, Xue-Yan; Gao, Yuan; Ng, David; Michalopoulou, Evdokia; George, Shanu; Adrover, Jose M.; Sun, Lijuan; Albrengues, Jean; Dassler-Plenker, Juliane; Han, Xiao; Wan, Ledong; Wu, Xiaoli S.; Shui, Longling S.; Huang, Yu-Han; Liu, Bodu; Su, Chang; Spector, David L.; Vakoc, Christopher R.; VanAelst, Linda; Egeblad, Mikala
errShare
errSave
Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA sequencing datasets
errSTEM CELL REPORTS
IF5.1
err2023-11-01
err2
errOAAI
errHazra, Rasmani; Utama, Raditya; Naik, Payal; Dobin, Alexander; Spector, David L.
errShare
errSave
Long non-coding RNAs: definitions, functions, challenges and recommendations
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2023-01-03
err711
errOAAI
errMattick, John S. S.; Amaral, Paulo P. P.; Carninci, Piero; Carpenter, Susan; Chang, Howard Y. Y.; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E. E.; Fitzgerald, Katherine A. A.; Gingeras, Thomas R. R.; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B. B.; Lee, Jeannie T. T.; Mendell, Joshua T. T.; Mercer, Timothy R. R.; Moore, Kathryn J. J.; Nakagawa, Shinichi; Rinn, John L. L.; Spector, David L. L.; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E. E.; Wu, Mian
errShare
errSave
Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment
errDEVELOPMENTAL CELL
IF8.7
err2022-11-01
err11
errOAAI
errHazra, Rasmani; Brine, Lily; Garcia, Libia; Benz, Brian; Chirathivat, Napon; Shen, Michael M.; Wilkinson, John Erby; Lyons, Scott K.; Spector, David L.
errShare
errSave
Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage
errNATURE COMMUNICATIONS
IF15.7
err2022-10-10
err1
errOAAI
errBalasooriya, Gayan, I; Spector, David L.
errShare
errSave
Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics
errCANCER RESEARCH
IF16.6
err2022-02-18
err31
errOAAI
errBhatia, Sonam; Kramer, Melissa; Russo, Suzanne; Naik, Payal; Arun, Gayatri; Brophy, Kyle; Andrews, Peter; Fan, Cheng; Perou, Charles M.; Preall, Jonathan; Ha, Taehoon; Plenker, Dennis; Tuveson, David A.; Rishi, Arvind; Wilkinson, John E.; McCombie, W. Richard; Kostroff, Karen; Spector, David L.
errShare
errSave
Safety and effectiveness of 1-stage conversion of adjustable gastric band-to-sleeve gastrectomy: a single-institution case-control study
errSURGERY FOR OBESITY AND RELATED DISEASES
IF3.8
err2022-01-01
err3
PREAI
errSenturk, James Clark; Sharma, Ragini; Tavakkoli, Ali; Vernon, Ashley; Spector, David; Robinson, Malcolm; Sheu, Eric; Shikora, Scott
errShare
errSave
Noncoding RNAs: biology and applications-a Keystone Symposia report
errANNALS OF THE NEW YORK ACADEMY OF SCIENCES
IF4.8
err2021-11-17
err16
errOAAI
errCable, Jennifer; Heard, Edith; Hirose, Tetsuro; Prasanth, Kannanganattu, V; Chen, Ling-Ling; Henninger, Jonathan E.; Quinodoz, Sofia A.; Spector, David L.; Diermeier, Sarah D.; Porman, Allison M.; Kumar, Dhiraj; Feinberg, Mark W.; Shen, Xiaohua; Unfried, Juan Pablo; Johnson, Rory; Chen, Chun-Kan; Wilusz, Jeremy E.; Lempradl, Adelheid; McGeary, Sean E.; Wahba, Lamia; Pyle, Anna Marie; Hargrove, Amanda E.; Simon, Matthew D.; Marcia, Marco; Przanowska, Roza K.; Chang, Howard Y.; Jaffrey, Samie R.; Contreras, Lydia M.; Chen, Qi; Shi, Junchao; Mendell, Joshua T.; He, Lin; Song, Erwei; Rinn, John L.; Lalwani, Mukesh Kumar; Kalem, Murat Can; Chuong, Edward B.; Maquat, Lynne E.; Liu, Xuhang
errShare
errSave
PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR
errELIFE
IF0
err2021-05-18
err17
errOAAI
errYu, Allen T.; Berasain, Carmen; Bhatia, Sonam; Rivera, Keith; Liu, Bodu; Rigo, Frank; Pappin, Darryl J.; Spector, David L.
errShare
errSave
MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression
errNATURE COMMUNICATIONS
IF15.7
err2020-12-22
err64
errOAAI
errChang, Kung-Chi; Diermeier, Sarah D.; Yu, Allen T.; Brine, Lily D.; Russo, Suzanne; Bhatia, Sonam; Alsudani, Habeeb; Kostroff, Karen; Bhuiya, Tawfiqul; Brogi, Edi; Pappin, Darryl J.; Bennett, C. Frank; Rigo, Frank; Spector, David L.
errShare
errSave
Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing
errGENOME RESEARCH
IF5.5
err2020-09-04
err69
errOAAI
errAganezov, Sergey; Goodwin, Sara; Sherman, Rachel M.; Sedlazeck, Fritz J.; Arun, Gayatri; Bhatia, Sonam; Lee, Isac; Kirsche, Melanie; Wappel, Robert; Kramer, Melissa; Kostroff, Karen; Spector, David L.; Timp, Winston; McCombie, W. Richard; Schatz, Michael C.
errShare
errSave
MALAT1 Long Non-Coding RNA: Functional Implications
errnon coding rna research
IF3
err2020-06-03
err188
errOAAI
errArun, Gayatri; Aggarwal, Disha; Spector, David L.
errShare
errSave

Research Directions

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Co-authors
Cooperation Journals
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H-index: 164 · Papers: 433
H
Howard Y. Chang
H-index: 162 · Papers: 736
R
Richard A. Young
H-index: 158 · Papers: 702
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