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Design of sensitive monospecific and bispecific synthetic chimeric T cell receptors for cancer therapy Simon, Sylvain; Bugos, Grace; Prins, Rachel; Rajan, Anusha; Palani, Arulmozhi; Heyer, Kersten; Stevens, Andrew; Zeng, Longhui; Thompson, Kirsten A.; Atilla, Pinar A.; Price, Jason P.; Kluesner, Mitchell G.; Jaeger-Ruckstuhl, Carla A.; Shabaneh, Tamer B.; Olson, James M.; Su, Xiaolei; Riddell, Stanley R. Share Save
Histone marks identify novel transcription factors that parse CAR-T subset-of-origin, clinical potential and expansion Fiorenza, S.; Zheng, Y.; Purushe, J.; Bock, T. J.; Sarthy, J.; Janssens, D. H.; Sheih, A. S.; Kimble, E. L.; Kirchmeier, D.; Phi, T. D.; Gauthier, J.; Hirayama, A. V.; Riddell, S. R.; Wu, Q.; Gottardo, R.; Maloney, D. G.; Yang, J. Y. H.; Henikoff, S.; Turtle, C. J. Share Save
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target (vol 132, e157101, 2022) Le, Quy; Hadland, Brandon; Smith, Jenny L.; Leonti, Amanda; Huang, Benjamin J.; Ries, Rhonda; Hylkema, Tiffany A.; Castro, Sommer; Tang, Thao T.; Mckay, Cyd N.; Perkins, Lakeisha; Pardo, Laura; Sarthy, Jay; Beckman, Amy K.; Williams, Robin; Idemmili, Rhonda; Furlan, Scott; Ishida, Takashi; Call, Lindsey; Srivastava, Shivani; Loeb, Anisha M.; Milano, Filippo; Imren, Suzan; Morris, Shelli M.; Pakiam, Fiona; Olson, Jim M.; Loken, Michael R.; Brodersen, Lisa; Riddell, Stanley R.; Tarlock, Katherine; Bernstein, Irwin D.; Loeb, Keith R.; Meshinchi, Soheil Share Save
CD8 T cells with an exhaustion-like phenotype remain highly functional in hematologic tumors Minnie, Simone; Waltner, Olivia; Zhang, Ping; Takahashi, Shuichiro; Nemychenkov, Nicole; Ensbey, Kathleen; Legg, Samuel; Comstock, Melissa; Boiko, Julie; Bhise, Shruti; Wilkens, Alec; Koyama, Motoko; Dhodapkar, Madhav; Chesi, Marta; Riddell, Stanley; Green, Damian; Spencer, Andrew Share Save
CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells Schreiber, Sophia; Dressler, Lisa S.; Loffredo-Verde, Eva; Asen, Theresa; Faerber, Stephanie; Wang, Wenshi; Groll, Tanja; Chakraborty, Anindita; Kolbe, Fenna; Kreer, Christoph; Kosinska, Anna D.; Simon, Sylvain; Urban, Stephan; Klein, Florian; Riddell, Stanley R.; Protzer, Ulrike Share Save
TIM-3+ CD8 T cells with a terminally exhausted phenotype retain functional capacity in hematological malignancies Minnie, Simone A.; Waltner, Olivia G.; Zhang, Ping; Takahashi, Shuichiro; Nemychenkov, Nicole S.; Ensbey, Kathleen S.; Schmidt, Christine R.; Legg, Samuel R. W.; Comstock, Melissa; Boiko, Julie R.; Nelson, Ethan; Bhise, Shruti S.; Wilkens, Alec B.; Koyama, Motoko; Dhodapkar, Madhav V.; Chesi, Marta; Riddell, Stanley R.; Green, Damian J.; Spencer, Andrew; Furlan, Scott N.; Hill, Geoffrey R. Share Save
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks Jaeger-Ruckstuhl, Carla A.; Lo, Yun; Fulton, Elena; Waltner, Olivia G.; Shabaneh, Tamer B.; Simon, Sylvain; Muthuraman, Pranav V.; Correnti, Colin E.; Newsom, Oliver J.; Engstrom, Ian A.; Kanaan, Sami B.; Bhise, Shruti S.; Peralta, Jobelle M. C.; Ruff, Raymond; Price, Jason P.; Stull, Sylvia M.; Stevens, Andrew R.; Bugos, Grace; Kluesner, Mitchell G.; Voillet, Valentin; Muhunthan, Vishaka; Morrish, Fionnuala; Olson, James M.; Gottardo, Raphaeeurol; Sarthy, Jay F.; Henikoff, Steven; Sullivan, Lucas B.; Furlan, Scott N.; Riddell, Stanley R. Share Save
Timing of anti-PD-L1 antibody initiation affects efficacy/toxicity of CD19 CAR T-cell therapy for large B-cell lymphoma Hirayama, Alexandre V.; Kimble, Erik L.; Wright, Jocelyn H.; Fiorenza, Salvatore; Gauthier, Jordan; Voutsinas, Jenna M.; Wu, Qian; Yeung, Cecilia C. S.; Gazeau, Nicolas; Pender, Barbara S.; Kirchmeier, Delaney R.; Torkelson, Aiko; Chutnik, Abigail N.; Cassaday, Ryan D.; Chapuis, Aude G.; Green, Damian J.; Kiem, Hans -Peter; Milano, Filippo; Shadman, Mazyar; Till, Brian G.; Riddell, Stanley R.; Maloney, David G.; Turtle, Cameron J. Share Save
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Factors associated with long-term outcomes of CD19 CAR T-cell therapy for relapsed/refractory CLL Liang, Emily C.; Albittar, Aya; Huang, Jennifer J.; Hirayama, Alexandre, V; Kimble, Erik L.; Portuguese, Andrew J.; Chapuis, Aude; Shadman, Mazyar; Till, Brian G.; Cassaday, Ryan D.; Milano, Filippo; Kiem, Hans -Peter; Riddell, Stanley R.; Turtle, Cameron J.; Maloney, David G.; Gauthier, Jordan Share Save
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Compromised antigen binding and signaling interfere with bispecific CD19 and CD79a chimeric antigen receptor function Leung, Isabel; Templeton, Megan L.; Lo, Yun; Rajan, Anusha; Stull, Sylvia M.; Garrison, Sarah M.; Salter, Alexander I.; Smythe, Kimberly S.; Correnti, Colin E.; Srivastava, Shivani; Yeung, Cecilia C. S.; Riddell, Stanley R. Share Save
A novel polymer-conjugated human IL-15 improves efficacy of CD19-targeted CAR T-cell immunotherapy Hirayama, Alexandre, V; Chou, Cassie K.; Miyazaki, Takahiro; Steinmetz, Rachel N.; Di, Henna A.; Fraessle, Simon P.; Gauthier, Jordan; Fiorenza, Salvatore; Hawkins, Reed M.; Overwijk, Willem W.; Riddell, Stanley R.; Marcondes, Mario Q.; Turtle, Cameron J. Share Save
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CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target Le, Quy; Hadland, Brandon; Smith, Jenny L.; Leonti, Amanda; Huang, Benjamin J.; Ries, Rhonda; Hylkema, Tiffany A.; Castro, Sommer; Tang, Thao T.; McKay, Cyd N.; Perkins, LaKeisha; Pardo, Laura; Sarthy, Jay; Beckman, Amy K.; Williams, Robin; Idemmili, Rhonda; Furlan, Scott; Ishida, Takashi; Call, Lindsey; Srivastava, Shivani; Loeb, Anisha M.; Milano, Filippo; Imren, Suzan; Morris, Shelli M.; Pakiam, Fiona; Olson, Jim M.; Loken, Michael R.; Brodersen, Lisa; Riddell, Stanley R.; Tarlock, Katherine; Bernstein, Irwin D.; Loeb, Keith R.; Meshinchi, Soheil Share Save
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy Quijano-Rubio, Alfredo; Bhuiyan, Aladdin M.; Yang, Huilin; Leung, Isabel; Bello, Elisa; Ali, Lestat R.; Zhangxu, Kevin; Perkins, Jilliane; Chun, Jung-Ho; Wang, Wentao; Lajoie, Marc J.; Ravichandran, Rashmi; Kuo, Yun-Huai; Dougan, Stephanie K.; Riddell, Stanley R.; Spangler, Jamie B.; Dougan, Michael; Silva, Daniel-Adriano; Baker, David Share Save
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activity Guener, Goekhan; Assfalg, Marlene; Zhao, Kai; Dreyer, Tobias; Lahiri, Shibojyoti; Lo, Yun; Slivinschi, Bianca Ionela; Imhof, Axel; Jocher, Georg; Strohm, Laura; Behrends, Christian; Langosch, Dieter; Bronger, Holger; Nimsky, Christopher; Bartsch, Joerg W.; Riddell, Stanley R.; Steiner, Harald; Lichtenthaler, Stefan F. Share Save
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